TY  - JOUR
AU  - Živković, Ivana
AU  - Šavikin, Katarina
AU  - Živković, Jelena
AU  - Zdunić, Gordana
AU  - Janković, Teodora
AU  - Lazić, Dejan
AU  - Radin, Dragoslava
PY  - 2021
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/5834
AB  - Human noroviruses (HuNoV) are the dominant cause of viral gastroenteritis in all age groups worldwide. In this study, we investigated the effects of pomegranate peel extract (PPE) on the reduction of HuNoV in different food models, on surfaces of fresh produce (green onion and cherry tomato), in low-fat milk, and simulated gastrointestinal fluids. The antiviral efficacy of PPE against HuNoV was evaluated by quantifying the number of residual virus genomes using a quantitative reverse transcription PCR (qRT-PCR) assay. Pomegranate peel, considered as a waste product of industrial processing, is known for beneficial health effects and broad antimicrobial activity due to the high content of phenolic compounds and tannins. PPE showed significant antiviral properties against HuNoV both in phosphate-buffered saline (PBS) and simulated gastric fluid. The reduction of HuNoV by pomegranate juice was lower than with PPE, which could be attributed to the lower content of antimicrobial compounds. A pretreatment of cherry tomato and green onion surfaces with PPE significantly reduced the amount of HuNoV particles that adhered to those surfaces during subsequent virus suspension treatment. A detrimental effect of PPE on HuNoV structure was confirmed by transmission electron microscopy. Our results indicate that PPE is a natural antiviral agent effective against food-borne noroviruses.
PB  - Springer
T2  - Plant Foods for Human Nutrition
T1  - Antiviral Effects of Pomegranate Peel Extracts on Human Norovirus in Food Models and Simulated Gastrointestinal Fluids
DO  - 10.1007/s11130-021-00895-7
ER  - 

@article{
author = "Živković, Ivana and Šavikin, Katarina and Živković, Jelena and Zdunić, Gordana and Janković, Teodora and Lazić, Dejan and Radin, Dragoslava",
year = "2021",
abstract = "Human noroviruses (HuNoV) are the dominant cause of viral gastroenteritis in all age groups worldwide. In this study, we investigated the effects of pomegranate peel extract (PPE) on the reduction of HuNoV in different food models, on surfaces of fresh produce (green onion and cherry tomato), in low-fat milk, and simulated gastrointestinal fluids. The antiviral efficacy of PPE against HuNoV was evaluated by quantifying the number of residual virus genomes using a quantitative reverse transcription PCR (qRT-PCR) assay. Pomegranate peel, considered as a waste product of industrial processing, is known for beneficial health effects and broad antimicrobial activity due to the high content of phenolic compounds and tannins. PPE showed significant antiviral properties against HuNoV both in phosphate-buffered saline (PBS) and simulated gastric fluid. The reduction of HuNoV by pomegranate juice was lower than with PPE, which could be attributed to the lower content of antimicrobial compounds. A pretreatment of cherry tomato and green onion surfaces with PPE significantly reduced the amount of HuNoV particles that adhered to those surfaces during subsequent virus suspension treatment. A detrimental effect of PPE on HuNoV structure was confirmed by transmission electron microscopy. Our results indicate that PPE is a natural antiviral agent effective against food-borne noroviruses.",
publisher = "Springer",
journal = "Plant Foods for Human Nutrition",
title = "Antiviral Effects of Pomegranate Peel Extracts on Human Norovirus in Food Models and Simulated Gastrointestinal Fluids",
doi = "10.1007/s11130-021-00895-7"
}

Živković, I., Šavikin, K., Živković, J., Zdunić, G., Janković, T., Lazić, D.,& Radin, D.. (2021). Antiviral Effects of Pomegranate Peel Extracts on Human Norovirus in Food Models and Simulated Gastrointestinal Fluids. in Plant Foods for Human Nutrition
Springer..
https://doi.org/10.1007/s11130-021-00895-7

Živković I, Šavikin K, Živković J, Zdunić G, Janković T, Lazić D, Radin D. Antiviral Effects of Pomegranate Peel Extracts on Human Norovirus in Food Models and Simulated Gastrointestinal Fluids. in Plant Foods for Human Nutrition. 2021;.
doi:10.1007/s11130-021-00895-7 .

Živković, Ivana, Šavikin, Katarina, Živković, Jelena, Zdunić, Gordana, Janković, Teodora, Lazić, Dejan, Radin, Dragoslava, "Antiviral Effects of Pomegranate Peel Extracts on Human Norovirus in Food Models and Simulated Gastrointestinal Fluids" in Plant Foods for Human Nutrition (2021),
https://doi.org/10.1007/s11130-021-00895-7 . .

TY  - JOUR
AU  - Živković, Jelena
AU  - Jadranin, Milka
AU  - Pržić, Zoran
AU  - Marković, Nebojša
AU  - Sokolović, Danijel
AU  - Šavikin, Katarina
AU  - Menković, Nebojša
PY  - 2021
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/5830
AB  - In this study, we have analyzed the anthocyanin composition of skin extracts of three red grape varieties Prokupac, Evita and Čokot Zemun in order to distinguish these cultivars based on their anthocyanin profile. Also, mechanical analysis of grape bunches and berries was performed. According to our results, seventeen anthocyanins were identified using LC/MS technique and quantitative differences were recorded using HPLC-DAD method. The highest content of total anthocyanins was obtained for Evita variety and the lowest one was recorded in Prokupac. Also, clear differences were observed in anthocyanins ratios. In comparison to Prokupac and Evita varieties, Čokot Zemun was characterized with a high content of coumaroyl derivatives of anthocyanin compounds, while high levels of acetylated derivatives were recorded in Prokupac. Data reported in this study represent a certain contribution to a database of mechanical properties and chemical composition of grape varieties originating from Balkan.
PB  - John Wiley and Sons Inc
T2  - Chemistry and Biodiversity
T1  - Varietal Differences of Prokupac, Evita and Čokot Zemun Based onTheir Anthocyanins Content in Grape Skin Extract
DO  - 10.1002/cbdv.202000858
ER  - 

@article{
author = "Živković, Jelena and Jadranin, Milka and Pržić, Zoran and Marković, Nebojša and Sokolović, Danijel and Šavikin, Katarina and Menković, Nebojša",
year = "2021",
abstract = "In this study, we have analyzed the anthocyanin composition of skin extracts of three red grape varieties Prokupac, Evita and Čokot Zemun in order to distinguish these cultivars based on their anthocyanin profile. Also, mechanical analysis of grape bunches and berries was performed. According to our results, seventeen anthocyanins were identified using LC/MS technique and quantitative differences were recorded using HPLC-DAD method. The highest content of total anthocyanins was obtained for Evita variety and the lowest one was recorded in Prokupac. Also, clear differences were observed in anthocyanins ratios. In comparison to Prokupac and Evita varieties, Čokot Zemun was characterized with a high content of coumaroyl derivatives of anthocyanin compounds, while high levels of acetylated derivatives were recorded in Prokupac. Data reported in this study represent a certain contribution to a database of mechanical properties and chemical composition of grape varieties originating from Balkan.",
publisher = "John Wiley and Sons Inc",
journal = "Chemistry and Biodiversity",
title = "Varietal Differences of Prokupac, Evita and Čokot Zemun Based onTheir Anthocyanins Content in Grape Skin Extract",
doi = "10.1002/cbdv.202000858"
}

Živković, J., Jadranin, M., Pržić, Z., Marković, N., Sokolović, D., Šavikin, K.,& Menković, N.. (2021). Varietal Differences of Prokupac, Evita and Čokot Zemun Based onTheir Anthocyanins Content in Grape Skin Extract. in Chemistry and Biodiversity
John Wiley and Sons Inc..
https://doi.org/10.1002/cbdv.202000858

Živković J, Jadranin M, Pržić Z, Marković N, Sokolović D, Šavikin K, Menković N. Varietal Differences of Prokupac, Evita and Čokot Zemun Based onTheir Anthocyanins Content in Grape Skin Extract. in Chemistry and Biodiversity. 2021;.
doi:10.1002/cbdv.202000858 .

Živković, Jelena, Jadranin, Milka, Pržić, Zoran, Marković, Nebojša, Sokolović, Danijel, Šavikin, Katarina, Menković, Nebojša, "Varietal Differences of Prokupac, Evita and Čokot Zemun Based onTheir Anthocyanins Content in Grape Skin Extract" in Chemistry and Biodiversity (2021),
https://doi.org/10.1002/cbdv.202000858 . .

TY  - JOUR
AU  - Kokina, Mariia
AU  - Salević, Ana
AU  - Kalušević, Ana
AU  - Lević, Steva
AU  - Pantić, Milena
AU  - Pljevljakusić, Dejan
AU  - Savikin, Katarina
AU  - Shamtsyan, Mark
AU  - Nikšić, Miomir
AU  - Nedović, Viktor
PY  - 2019
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4930
AB  - The study assessed the antimicrobial and antioxidant activities of commonly used and commercially available essential oils as an alternative to synthetic preservatives. The plant sources were as follows: lavender (Lavandula angustifolia), tea tree (Melaleuca alternifolia), bergamot (Citrus bergamia) and peppermint (Mentha piperita). The antioxidant activity of essential oils was tested by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) methods. The microdilution broth susceptibility assay revealed that lavender and bergamot essential oils were more efficient in inhibiting the bacterial growth than other tested oils, with the minimum inhibitory concentration of 5 mu g/mL. This study also reports the successful implementation of an electrostatic extrusion technique for encapsulating essential oils into alginate beads, which enables the essential oils to maintain their free radical scavenging ability over time.
PB  - Faculty Food Technology Biotechnology, Zagreb
T2  - Food Technology and Biotechnology
T1  - Characterization, Antioxidant and Antibacterial Activity of Essential Oils and Their Encapsulation into Biodegradable Material Followed by Freeze Drying
EP  - 289
IS  - 2
SP  - 282
VL  - 57
DO  - 10.17113/ftb.57.02.19.5957
ER  - 

@article{
author = "Kokina, Mariia and Salević, Ana and Kalušević, Ana and Lević, Steva and Pantić, Milena and Pljevljakusić, Dejan and Savikin, Katarina and Shamtsyan, Mark and Nikšić, Miomir and Nedović, Viktor",
year = "2019",
abstract = "The study assessed the antimicrobial and antioxidant activities of commonly used and commercially available essential oils as an alternative to synthetic preservatives. The plant sources were as follows: lavender (Lavandula angustifolia), tea tree (Melaleuca alternifolia), bergamot (Citrus bergamia) and peppermint (Mentha piperita). The antioxidant activity of essential oils was tested by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) methods. The microdilution broth susceptibility assay revealed that lavender and bergamot essential oils were more efficient in inhibiting the bacterial growth than other tested oils, with the minimum inhibitory concentration of 5 mu g/mL. This study also reports the successful implementation of an electrostatic extrusion technique for encapsulating essential oils into alginate beads, which enables the essential oils to maintain their free radical scavenging ability over time.",
publisher = "Faculty Food Technology Biotechnology, Zagreb",
journal = "Food Technology and Biotechnology",
title = "Characterization, Antioxidant and Antibacterial Activity of Essential Oils and Their Encapsulation into Biodegradable Material Followed by Freeze Drying",
pages = "289-282",
number = "2",
volume = "57",
doi = "10.17113/ftb.57.02.19.5957"
}

Kokina, M., Salević, A., Kalušević, A., Lević, S., Pantić, M., Pljevljakusić, D., Savikin, K., Shamtsyan, M., Nikšić, M.,& Nedović, V.. (2019). Characterization, Antioxidant and Antibacterial Activity of Essential Oils and Their Encapsulation into Biodegradable Material Followed by Freeze Drying. in Food Technology and Biotechnology
Faculty Food Technology Biotechnology, Zagreb., 57(2), 282-289.
https://doi.org/10.17113/ftb.57.02.19.5957

Kokina M, Salević A, Kalušević A, Lević S, Pantić M, Pljevljakusić D, Savikin K, Shamtsyan M, Nikšić M, Nedović V. Characterization, Antioxidant and Antibacterial Activity of Essential Oils and Their Encapsulation into Biodegradable Material Followed by Freeze Drying. in Food Technology and Biotechnology. 2019;57(2):282-289.
doi:10.17113/ftb.57.02.19.5957 .

Kokina, Mariia, Salević, Ana, Kalušević, Ana, Lević, Steva, Pantić, Milena, Pljevljakusić, Dejan, Savikin, Katarina, Shamtsyan, Mark, Nikšić, Miomir, Nedović, Viktor, "Characterization, Antioxidant and Antibacterial Activity of Essential Oils and Their Encapsulation into Biodegradable Material Followed by Freeze Drying" in Food Technology and Biotechnology, 57, no. 2 (2019):282-289,
https://doi.org/10.17113/ftb.57.02.19.5957 . .

TY  - JOUR
AU  - Ćujić-Nikolić, Nada
AU  - Stanisavljević, Nemanja
AU  - Savikin, Katarina
AU  - Kalušević, Ana
AU  - Nedović, Viktor
AU  - Samardzić, Jelena
AU  - Janković, Teodora
PY  - 2019
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4910
AB  - Aim: Microencapsulation of chokeberry extracts was performed in order to improve functionality, stability, and bioavailability of extracted polyphenols. Methods: Chokeberry fruits and juice by-product (waste) extracts were spray-dried by using two carriers, maltodextrin and skimmed milk. Morphological and physicochemical characteristics of the obtained powders were analysed. In vitro simulated digestion model was used as an indicator of polyphenolics bioavailability. Results: The moisture content varied between 3.39 and 4.61%, zeta potential had negative values (35-39 mV), maltodetrin powders were smaller (4.27-5.12 mu m) compared to skimmed ones (8.50-11.01 mu m). All microparticles exhibited high encapsulation efficiency of total polyphenols and anthocyanins (73-97% and 63-96%, respectively). For both extract types, maltodextrin powders released higher phenolics content compared to skimmed milk. During in vitro digestion, maltodextrin exhibited a higher protective effect on both active compounds. Conclusion: Taking into account the obtained results, chokeberry polyphenols stability might be improved using spray drying technique, and maltodextrin showed better properties.
PB  - Taylor & Francis Ltd, Abingdon
T2  - Journal of Microencapsulation
T1  - Chokeberry polyphenols preservation using spray drying: effect of encapsulation using maltodextrin and skimmed milk on their recovery following in vitro digestion
EP  - 703
IS  - 8
SP  - 693
VL  - 36
DO  - 10.1080/02652048.2019.1667448
ER  - 

@article{
author = "Ćujić-Nikolić, Nada and Stanisavljević, Nemanja and Savikin, Katarina and Kalušević, Ana and Nedović, Viktor and Samardzić, Jelena and Janković, Teodora",
year = "2019",
abstract = "Aim: Microencapsulation of chokeberry extracts was performed in order to improve functionality, stability, and bioavailability of extracted polyphenols. Methods: Chokeberry fruits and juice by-product (waste) extracts were spray-dried by using two carriers, maltodextrin and skimmed milk. Morphological and physicochemical characteristics of the obtained powders were analysed. In vitro simulated digestion model was used as an indicator of polyphenolics bioavailability. Results: The moisture content varied between 3.39 and 4.61%, zeta potential had negative values (35-39 mV), maltodetrin powders were smaller (4.27-5.12 mu m) compared to skimmed ones (8.50-11.01 mu m). All microparticles exhibited high encapsulation efficiency of total polyphenols and anthocyanins (73-97% and 63-96%, respectively). For both extract types, maltodextrin powders released higher phenolics content compared to skimmed milk. During in vitro digestion, maltodextrin exhibited a higher protective effect on both active compounds. Conclusion: Taking into account the obtained results, chokeberry polyphenols stability might be improved using spray drying technique, and maltodextrin showed better properties.",
publisher = "Taylor & Francis Ltd, Abingdon",
journal = "Journal of Microencapsulation",
title = "Chokeberry polyphenols preservation using spray drying: effect of encapsulation using maltodextrin and skimmed milk on their recovery following in vitro digestion",
pages = "703-693",
number = "8",
volume = "36",
doi = "10.1080/02652048.2019.1667448"
}

Ćujić-Nikolić, N., Stanisavljević, N., Savikin, K., Kalušević, A., Nedović, V., Samardzić, J.,& Janković, T.. (2019). Chokeberry polyphenols preservation using spray drying: effect of encapsulation using maltodextrin and skimmed milk on their recovery following in vitro digestion. in Journal of Microencapsulation
Taylor & Francis Ltd, Abingdon., 36(8), 693-703.
https://doi.org/10.1080/02652048.2019.1667448

Ćujić-Nikolić N, Stanisavljević N, Savikin K, Kalušević A, Nedović V, Samardzić J, Janković T. Chokeberry polyphenols preservation using spray drying: effect of encapsulation using maltodextrin and skimmed milk on their recovery following in vitro digestion. in Journal of Microencapsulation. 2019;36(8):693-703.
doi:10.1080/02652048.2019.1667448 .

Ćujić-Nikolić, Nada, Stanisavljević, Nemanja, Savikin, Katarina, Kalušević, Ana, Nedović, Viktor, Samardzić, Jelena, Janković, Teodora, "Chokeberry polyphenols preservation using spray drying: effect of encapsulation using maltodextrin and skimmed milk on their recovery following in vitro digestion" in Journal of Microencapsulation, 36, no. 8 (2019):693-703,
https://doi.org/10.1080/02652048.2019.1667448 . .

TY  - JOUR
AU  - Zdunić, Gordana
AU  - Godjevac, Dejan
AU  - Savikin, Katarina
AU  - Krivokuca, Dragana
AU  - Mihailović, Milica
AU  - Pržić, Zoran
AU  - Marković, Nebojša
PY  - 2019
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4936
AB  - Grape pomace (grape skin, seeds, and stems) represents a valuable source of bioactive compounds, thus the interest in making use of these wine waste products is increasing. Prokupac is an autochthonous Serbian variety of black grape with a long tradition in production of red wine. Identification of the superficial polyphenolic compounds by LC/MS revealed presence of 19 compounds including hydroxybenzoic acid derivatives, ellagic acid derivatives, flavan-3-ol monomers, proanthocyanidins, and flavonols. Catechin and epicatechin together with proanthocyanidins were the most abundant compounds and the highest content of phenolic compounds was determined in Prokupac clones 43/1, 40/1, and 40/2. Grape seed oil consisted of dominantly UFA (87-95 %) where methyl linoleate was the most abundant in all samples (69-81 %). Palmitic (3-8 %) and stearic acid (2-4 %) methyl esters were dominant SFA. Prokupac clone 43/3 was the most abundant in UFA (95 %) with the lowest percentage of SFA (5 %), while clones 41/1 and 43/5 had the lowest percentage of UFA (87 %) and the highest content of SFA (13 %). Favorable chemical profile of Prokupac clone seeds implicates its potential to be used as a raw material in further processing and possibility to be included as one of the quality parameters in further selection of the most interesting Prokupac clone.
PB  - Wiley-V C H Verlag Gmbh, Weinheim
T2  - Chemistry & Biodiversity
T1  - Grape Seed Polyphenols and Fatty Acids of Autochthonous Prokupac Vine Variety from Serbia
IS  - 7
VL  - 16
DO  - 10.1002/cbdv.201900053
ER  - 

@article{
author = "Zdunić, Gordana and Godjevac, Dejan and Savikin, Katarina and Krivokuca, Dragana and Mihailović, Milica and Pržić, Zoran and Marković, Nebojša",
year = "2019",
abstract = "Grape pomace (grape skin, seeds, and stems) represents a valuable source of bioactive compounds, thus the interest in making use of these wine waste products is increasing. Prokupac is an autochthonous Serbian variety of black grape with a long tradition in production of red wine. Identification of the superficial polyphenolic compounds by LC/MS revealed presence of 19 compounds including hydroxybenzoic acid derivatives, ellagic acid derivatives, flavan-3-ol monomers, proanthocyanidins, and flavonols. Catechin and epicatechin together with proanthocyanidins were the most abundant compounds and the highest content of phenolic compounds was determined in Prokupac clones 43/1, 40/1, and 40/2. Grape seed oil consisted of dominantly UFA (87-95 %) where methyl linoleate was the most abundant in all samples (69-81 %). Palmitic (3-8 %) and stearic acid (2-4 %) methyl esters were dominant SFA. Prokupac clone 43/3 was the most abundant in UFA (95 %) with the lowest percentage of SFA (5 %), while clones 41/1 and 43/5 had the lowest percentage of UFA (87 %) and the highest content of SFA (13 %). Favorable chemical profile of Prokupac clone seeds implicates its potential to be used as a raw material in further processing and possibility to be included as one of the quality parameters in further selection of the most interesting Prokupac clone.",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "Chemistry & Biodiversity",
title = "Grape Seed Polyphenols and Fatty Acids of Autochthonous Prokupac Vine Variety from Serbia",
number = "7",
volume = "16",
doi = "10.1002/cbdv.201900053"
}

Zdunić, G., Godjevac, D., Savikin, K., Krivokuca, D., Mihailović, M., Pržić, Z.,& Marković, N.. (2019). Grape Seed Polyphenols and Fatty Acids of Autochthonous Prokupac Vine Variety from Serbia. in Chemistry & Biodiversity
Wiley-V C H Verlag Gmbh, Weinheim., 16(7).
https://doi.org/10.1002/cbdv.201900053

Zdunić G, Godjevac D, Savikin K, Krivokuca D, Mihailović M, Pržić Z, Marković N. Grape Seed Polyphenols and Fatty Acids of Autochthonous Prokupac Vine Variety from Serbia. in Chemistry & Biodiversity. 2019;16(7).
doi:10.1002/cbdv.201900053 .

Zdunić, Gordana, Godjevac, Dejan, Savikin, Katarina, Krivokuca, Dragana, Mihailović, Milica, Pržić, Zoran, Marković, Nebojša, "Grape Seed Polyphenols and Fatty Acids of Autochthonous Prokupac Vine Variety from Serbia" in Chemistry & Biodiversity, 16, no. 7 (2019),
https://doi.org/10.1002/cbdv.201900053 . .

TY  - JOUR
AU  - Jovanović, Aleksandra A.
AU  - Balanc, Bojana
AU  - Djordjević, Verica B.
AU  - Ota, Ajda
AU  - Skrt, Mihaela
AU  - Savikin, Katarina
AU  - Bugarski, Branko
AU  - Nedović, Viktor
AU  - Ulrih, Nataša Poklar
PY  - 2019
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4992
AB  - Multifunctional liposomes incorporating beta-sitosterol were developed for delivery of gentisic acid (GA). The interactions of both compounds with phospholipid bilayer were interpreted viaeffects of different beta-sitosterol content (0, 20 and 50 mol %) and different gentisic acid to lipid ratio (n(GA)/n(lip) from 10(-5) to 1) on membrane fluidity and thermotropic properties. Multilamellar vesicles of phosphatidylcholines (with size range between 1350 and 1900 nm) effectively encapsulated GA (54%) when n(GA)/n(lip) was higher than 0.01. Suppression of lipid peroxidation was directly related to concentration of GA. The resistance to diffusion of gentisic acid from liposomes increased for (similar to)50% in samples incorporating 50 mol % beta-sitosterol compared to sterol-free liposomes. Finally, simulated in vitro gastrointestinal conditions showed that the release was mainly affected by low pH of simulated gastric fluid and the presence of cholates in simulated intestinal fluid, rather than by enzymes activity.
PB  - Elsevier, Amsterdam
T2  - Colloids and Surfaces B-Biointerfaces
T1  - Effect of gentisic acid on the structural-functional properties of liposomes incorporating beta-sitosterol
VL  - 183
DO  - 10.1016/j.colsurfb.2019.110422
ER  - 

@article{
author = "Jovanović, Aleksandra A. and Balanc, Bojana and Djordjević, Verica B. and Ota, Ajda and Skrt, Mihaela and Savikin, Katarina and Bugarski, Branko and Nedović, Viktor and Ulrih, Nataša Poklar",
year = "2019",
abstract = "Multifunctional liposomes incorporating beta-sitosterol were developed for delivery of gentisic acid (GA). The interactions of both compounds with phospholipid bilayer were interpreted viaeffects of different beta-sitosterol content (0, 20 and 50 mol %) and different gentisic acid to lipid ratio (n(GA)/n(lip) from 10(-5) to 1) on membrane fluidity and thermotropic properties. Multilamellar vesicles of phosphatidylcholines (with size range between 1350 and 1900 nm) effectively encapsulated GA (54%) when n(GA)/n(lip) was higher than 0.01. Suppression of lipid peroxidation was directly related to concentration of GA. The resistance to diffusion of gentisic acid from liposomes increased for (similar to)50% in samples incorporating 50 mol % beta-sitosterol compared to sterol-free liposomes. Finally, simulated in vitro gastrointestinal conditions showed that the release was mainly affected by low pH of simulated gastric fluid and the presence of cholates in simulated intestinal fluid, rather than by enzymes activity.",
publisher = "Elsevier, Amsterdam",
journal = "Colloids and Surfaces B-Biointerfaces",
title = "Effect of gentisic acid on the structural-functional properties of liposomes incorporating beta-sitosterol",
volume = "183",
doi = "10.1016/j.colsurfb.2019.110422"
}

Jovanović, A. A., Balanc, B., Djordjević, V. B., Ota, A., Skrt, M., Savikin, K., Bugarski, B., Nedović, V.,& Ulrih, N. P.. (2019). Effect of gentisic acid on the structural-functional properties of liposomes incorporating beta-sitosterol. in Colloids and Surfaces B-Biointerfaces
Elsevier, Amsterdam., 183.
https://doi.org/10.1016/j.colsurfb.2019.110422

Jovanović AA, Balanc B, Djordjević VB, Ota A, Skrt M, Savikin K, Bugarski B, Nedović V, Ulrih NP. Effect of gentisic acid on the structural-functional properties of liposomes incorporating beta-sitosterol. in Colloids and Surfaces B-Biointerfaces. 2019;183.
doi:10.1016/j.colsurfb.2019.110422 .

Jovanović, Aleksandra A., Balanc, Bojana, Djordjević, Verica B., Ota, Ajda, Skrt, Mihaela, Savikin, Katarina, Bugarski, Branko, Nedović, Viktor, Ulrih, Nataša Poklar, "Effect of gentisic acid on the structural-functional properties of liposomes incorporating beta-sitosterol" in Colloids and Surfaces B-Biointerfaces, 183 (2019),
https://doi.org/10.1016/j.colsurfb.2019.110422 . .

TY  - JOUR
AU  - Jovanović, Aleksandra A.
AU  - Balanc, Bojana
AU  - Djordjević, Verica B.
AU  - Savikin, Katarina
AU  - Nedović, Viktor
AU  - Bugarski, Branko
AU  - Poklar-Ulrih, Nataša
PY  - 2019
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/5187
AB  - The present study provides insight into changes in the liposomal membrane fluidity as a result of variation of structural components (two types of standard phospholipids - 1,2-dipalmitoyl-sn-glycerero3-phosphocholine, i.e. DPPC and 1-palmitoyl-2-oleoylglycerol-3-phosphocholine, i.e. POPC, one type of phospholipid mixture - Lipoid H and sterols - cholesterol and b-sitosterol), as well as variation in sterol concentration (5-50%). Fluorescence spectroscopy (anisotropy, r) has shown that DPPC liposomal membranes were more rigid compared to POPC and Lipoid H lipid bilayers. Furthermore, the increment of sterol concentration has caused a decrease in the membrane fluidity in all liposomal samples. On the other hand, phospholipid bilayers containing b-sitosterol has possessed better fluidity in comparison to their cholesterol parallels. Higher permeability of b-sitosterol liposomal membranes, as well as the beneficial effects of phytosterol on human health, favor the use of b-sitosterol in the preparation of liposomes as components of food, pharmaceutical and cosmetic products.
AB  - Prikazana studija daje uvid u promene fluidnosti lipozomalne membrane koje nastaju kao posledica promene strukturnih komponenata lipozoma (dve vrste standardnih fosfolipida - 1,2-dipalmitoil-snglicero-3-fosfoholin, odnosno DPPC i 1-palmitoil-2-oleoil-sn-glicero-3-fosfoholin, odnosno POPC, jedne vrste komercijalne fosfolipidne smeše - Lipoid H i sterola - holesterol i b-sitosterol), kao i promene udela sterola (0-50 mol %). Fluorimetrijska spektrofotometrija (anizotropija, r) pokazala je da su DPPC lipozomalne membrane bile rigidnije u poređenju sa POPC i Lipoid H lipidnim dvoslojima. Pored toga, povećenje koncentracije sterola prouzrokovalo je smanjenje permeabilnosti membrane u svim lipozomima. Sa druge strane, fosfolipidni dvosloji koji su sadržali b-sitosterol pokazali su veću fluidnost u poređenju sa njihovim paralelama sa holesterolom. Bolja permeabilnost b-sitosterol lipozomalnih membrana, kao i blagotvorni uticaji fitosterola na zdravlje ljudi favorizuju primenu b-sitosterola u pripremi lipozoma kao sastavnih delova prehrambenih, farmaceutskih i kozmetičkih proizvoda.
PB  - Savez inženjera i tehničara Srbije, Beograd
T2  - Tehnika
T1  - Fluorescence analysis of liposomal membranes permeability
T1  - Fluorimetrijska analiza permeabilnosti lipozomalnih membrana
EP  - 498
IS  - 4
SP  - 493
VL  - 74
DO  - 10.5937/tehnika1904493J
ER  - 

@article{
author = "Jovanović, Aleksandra A. and Balanc, Bojana and Djordjević, Verica B. and Savikin, Katarina and Nedović, Viktor and Bugarski, Branko and Poklar-Ulrih, Nataša",
year = "2019",
abstract = "The present study provides insight into changes in the liposomal membrane fluidity as a result of variation of structural components (two types of standard phospholipids - 1,2-dipalmitoyl-sn-glycerero3-phosphocholine, i.e. DPPC and 1-palmitoyl-2-oleoylglycerol-3-phosphocholine, i.e. POPC, one type of phospholipid mixture - Lipoid H and sterols - cholesterol and b-sitosterol), as well as variation in sterol concentration (5-50%). Fluorescence spectroscopy (anisotropy, r) has shown that DPPC liposomal membranes were more rigid compared to POPC and Lipoid H lipid bilayers. Furthermore, the increment of sterol concentration has caused a decrease in the membrane fluidity in all liposomal samples. On the other hand, phospholipid bilayers containing b-sitosterol has possessed better fluidity in comparison to their cholesterol parallels. Higher permeability of b-sitosterol liposomal membranes, as well as the beneficial effects of phytosterol on human health, favor the use of b-sitosterol in the preparation of liposomes as components of food, pharmaceutical and cosmetic products., Prikazana studija daje uvid u promene fluidnosti lipozomalne membrane koje nastaju kao posledica promene strukturnih komponenata lipozoma (dve vrste standardnih fosfolipida - 1,2-dipalmitoil-snglicero-3-fosfoholin, odnosno DPPC i 1-palmitoil-2-oleoil-sn-glicero-3-fosfoholin, odnosno POPC, jedne vrste komercijalne fosfolipidne smeše - Lipoid H i sterola - holesterol i b-sitosterol), kao i promene udela sterola (0-50 mol %). Fluorimetrijska spektrofotometrija (anizotropija, r) pokazala je da su DPPC lipozomalne membrane bile rigidnije u poređenju sa POPC i Lipoid H lipidnim dvoslojima. Pored toga, povećenje koncentracije sterola prouzrokovalo je smanjenje permeabilnosti membrane u svim lipozomima. Sa druge strane, fosfolipidni dvosloji koji su sadržali b-sitosterol pokazali su veću fluidnost u poređenju sa njihovim paralelama sa holesterolom. Bolja permeabilnost b-sitosterol lipozomalnih membrana, kao i blagotvorni uticaji fitosterola na zdravlje ljudi favorizuju primenu b-sitosterola u pripremi lipozoma kao sastavnih delova prehrambenih, farmaceutskih i kozmetičkih proizvoda.",
publisher = "Savez inženjera i tehničara Srbije, Beograd",
journal = "Tehnika",
title = "Fluorescence analysis of liposomal membranes permeability, Fluorimetrijska analiza permeabilnosti lipozomalnih membrana",
pages = "498-493",
number = "4",
volume = "74",
doi = "10.5937/tehnika1904493J"
}

Jovanović, A. A., Balanc, B., Djordjević, V. B., Savikin, K., Nedović, V., Bugarski, B.,& Poklar-Ulrih, N.. (2019). Fluorescence analysis of liposomal membranes permeability. in Tehnika
Savez inženjera i tehničara Srbije, Beograd., 74(4), 493-498.
https://doi.org/10.5937/tehnika1904493J

Jovanović AA, Balanc B, Djordjević VB, Savikin K, Nedović V, Bugarski B, Poklar-Ulrih N. Fluorescence analysis of liposomal membranes permeability. in Tehnika. 2019;74(4):493-498.
doi:10.5937/tehnika1904493J .

Jovanović, Aleksandra A., Balanc, Bojana, Djordjević, Verica B., Savikin, Katarina, Nedović, Viktor, Bugarski, Branko, Poklar-Ulrih, Nataša, "Fluorescence analysis of liposomal membranes permeability" in Tehnika, 74, no. 4 (2019):493-498,
https://doi.org/10.5937/tehnika1904493J . .

TY  - JOUR
AU  - Pljevljakusić, Dejan
AU  - Bigović, Dubravka
AU  - Janković, Teodora
AU  - Jelačić, Slavica
AU  - Savikin, Katarina
PY  - 2018
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4770
AB  - Sandy everlasting [Helichrysum arenarium (L.) Moench] is herbaceous perennial plant belonging to Asteraceae family and it is native to Europe, Central Asia, and China. It belongs to the section HELICHRYSUM (Asteraceae family, genus Helichrysum) along with H. plicatum DC. Prodr., which very similar phenolic profile and H. italicum (Roth), which is widely used for essential oil extraction. Its flowers have a long tradition in European ethnomedicine as a cholagogue, choleretic, hepatoprotective, and detoxifying herbal drug. The flowers are rich in phenolic compounds including flavonoids, chalcones, phenolic acids, coumarins, and pyrones. Apart frompolyphenols, other compounds such as sterols, lignans, and glycosides of aromatic compounds have been also isolated from H. arenarium. The majority of authors confirm that the most important group of compounds responsible for biological activities is flavonoids. Moreover, significant activities of naringenin, one of the main flavonoids of H. arenarium, were reported. On the other hand, there are no clinical data about testing the extracts or preparations based on H. arenarium. Although H. arenarium is well known in phytotherapy for its potential in the treatment of gallbladder disease and are classified as endangered species in a number of European countries, very few data about its cultivation are available in the literature.
PB  - Frontiers Media Sa, Lausanne
T2  - Frontiers in Plant Science
T1  - Sandy Everlasting (Helichrysum arenarium (L.) Moench): Botanical, Chemical and Biological Properties
VL  - 9
DO  - 10.3389/fpls.2018.01123
ER  - 

@article{
author = "Pljevljakusić, Dejan and Bigović, Dubravka and Janković, Teodora and Jelačić, Slavica and Savikin, Katarina",
year = "2018",
abstract = "Sandy everlasting [Helichrysum arenarium (L.) Moench] is herbaceous perennial plant belonging to Asteraceae family and it is native to Europe, Central Asia, and China. It belongs to the section HELICHRYSUM (Asteraceae family, genus Helichrysum) along with H. plicatum DC. Prodr., which very similar phenolic profile and H. italicum (Roth), which is widely used for essential oil extraction. Its flowers have a long tradition in European ethnomedicine as a cholagogue, choleretic, hepatoprotective, and detoxifying herbal drug. The flowers are rich in phenolic compounds including flavonoids, chalcones, phenolic acids, coumarins, and pyrones. Apart frompolyphenols, other compounds such as sterols, lignans, and glycosides of aromatic compounds have been also isolated from H. arenarium. The majority of authors confirm that the most important group of compounds responsible for biological activities is flavonoids. Moreover, significant activities of naringenin, one of the main flavonoids of H. arenarium, were reported. On the other hand, there are no clinical data about testing the extracts or preparations based on H. arenarium. Although H. arenarium is well known in phytotherapy for its potential in the treatment of gallbladder disease and are classified as endangered species in a number of European countries, very few data about its cultivation are available in the literature.",
publisher = "Frontiers Media Sa, Lausanne",
journal = "Frontiers in Plant Science",
title = "Sandy Everlasting (Helichrysum arenarium (L.) Moench): Botanical, Chemical and Biological Properties",
volume = "9",
doi = "10.3389/fpls.2018.01123"
}

Pljevljakusić, D., Bigović, D., Janković, T., Jelačić, S.,& Savikin, K.. (2018). Sandy Everlasting (Helichrysum arenarium (L.) Moench): Botanical, Chemical and Biological Properties. in Frontiers in Plant Science
Frontiers Media Sa, Lausanne., 9.
https://doi.org/10.3389/fpls.2018.01123

Pljevljakusić D, Bigović D, Janković T, Jelačić S, Savikin K. Sandy Everlasting (Helichrysum arenarium (L.) Moench): Botanical, Chemical and Biological Properties. in Frontiers in Plant Science. 2018;9.
doi:10.3389/fpls.2018.01123 .

Pljevljakusić, Dejan, Bigović, Dubravka, Janković, Teodora, Jelačić, Slavica, Savikin, Katarina, "Sandy Everlasting (Helichrysum arenarium (L.) Moench): Botanical, Chemical and Biological Properties" in Frontiers in Plant Science, 9 (2018),
https://doi.org/10.3389/fpls.2018.01123 . .

TY  - JOUR
AU  - Ćujić-Nikolić, Nada
AU  - Stanisavljević, Nemanja
AU  - Šavikin, Katarina
AU  - Kalušević, Ana
AU  - Nedović, Viktor
AU  - Bigović, Dubravka
AU  - Janković, Teodora
PY  - 2018
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4827
AB  - Due to its high content of phenolics, black chokeberry has been proposed as a health-promoting material, especially use of chokeberry extract as a food or pharmaceuticals. Chokeberry extract was spray-dried using gum Arabic as a carrier. The optimal conditions for the efficient microencapsulation of chokeberry extract using spray-drying technique have been investigated. The aim of our study was to obtain microparticles with the best potential to improve functionality and stability of extracted chokeberry polyphenols, and to investigate the possibility of microbeads to protect active compounds during simulated digestion process. Morphological characteristics of microbeads were analyzed using FTIR and SEM techniques. Zeta potential, particle size and moisture content were determined. Released total phenolics and total anthocyanins content as well as concentration of individual anthocyanins were quantified before and after digestion process. Microparticles exhibited high encapsulation efficiency up to 87%, and high content of released polyphenols was achieved. After in vitro simulated digestion phenolic compounds decreased by 11-24%, exhibited higher protective effect of gum Arabic. Our results showed that chokeberry microparticles obtained by spray drying method could be useful supplements or functional food. .
PB  - Institut za proučavanje lekovitog bilja Dr Josif Pančić, Beograd
T2  - Lekovite sirovine
T1  - Application of gum Arabic in the production of spray-dried chokeberry polyphenols, microparticles characterisation and in vitro digestion method
EP  - 16
IS  - 38
SP  - 9
DO  - 10.5937/leksir1838009C
ER  - 

@article{
author = "Ćujić-Nikolić, Nada and Stanisavljević, Nemanja and Šavikin, Katarina and Kalušević, Ana and Nedović, Viktor and Bigović, Dubravka and Janković, Teodora",
year = "2018",
abstract = "Due to its high content of phenolics, black chokeberry has been proposed as a health-promoting material, especially use of chokeberry extract as a food or pharmaceuticals. Chokeberry extract was spray-dried using gum Arabic as a carrier. The optimal conditions for the efficient microencapsulation of chokeberry extract using spray-drying technique have been investigated. The aim of our study was to obtain microparticles with the best potential to improve functionality and stability of extracted chokeberry polyphenols, and to investigate the possibility of microbeads to protect active compounds during simulated digestion process. Morphological characteristics of microbeads were analyzed using FTIR and SEM techniques. Zeta potential, particle size and moisture content were determined. Released total phenolics and total anthocyanins content as well as concentration of individual anthocyanins were quantified before and after digestion process. Microparticles exhibited high encapsulation efficiency up to 87%, and high content of released polyphenols was achieved. After in vitro simulated digestion phenolic compounds decreased by 11-24%, exhibited higher protective effect of gum Arabic. Our results showed that chokeberry microparticles obtained by spray drying method could be useful supplements or functional food. .",
publisher = "Institut za proučavanje lekovitog bilja Dr Josif Pančić, Beograd",
journal = "Lekovite sirovine",
title = "Application of gum Arabic in the production of spray-dried chokeberry polyphenols, microparticles characterisation and in vitro digestion method",
pages = "16-9",
number = "38",
doi = "10.5937/leksir1838009C"
}

Ćujić-Nikolić, N., Stanisavljević, N., Šavikin, K., Kalušević, A., Nedović, V., Bigović, D.,& Janković, T.. (2018). Application of gum Arabic in the production of spray-dried chokeberry polyphenols, microparticles characterisation and in vitro digestion method. in Lekovite sirovine
Institut za proučavanje lekovitog bilja Dr Josif Pančić, Beograd.(38), 9-16.
https://doi.org/10.5937/leksir1838009C

Ćujić-Nikolić N, Stanisavljević N, Šavikin K, Kalušević A, Nedović V, Bigović D, Janković T. Application of gum Arabic in the production of spray-dried chokeberry polyphenols, microparticles characterisation and in vitro digestion method. in Lekovite sirovine. 2018;(38):9-16.
doi:10.5937/leksir1838009C .

Ćujić-Nikolić, Nada, Stanisavljević, Nemanja, Šavikin, Katarina, Kalušević, Ana, Nedović, Viktor, Bigović, Dubravka, Janković, Teodora, "Application of gum Arabic in the production of spray-dried chokeberry polyphenols, microparticles characterisation and in vitro digestion method" in Lekovite sirovine, no. 38 (2018):9-16,
https://doi.org/10.5937/leksir1838009C . .

TY  - JOUR
AU  - Živković, Ivana
AU  - Šavikin, Katarina
AU  - Zdunić, Gordana
AU  - Živković, Jelena
AU  - Bigović, Dubravka
AU  - Menković, Nebojša
AU  - Radin, Dragoslava
PY  - 2018
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4828
AB  - Medicinal plant extracts (MPE) have a broad antimicrobial activity, including antiviral effects. In our study, eleven dry extract of ten different medicinal plant prepared with two solvents (5%, dimethyl sulfoxide (DMSO) and 30% ethanol in 5% DMSO) in different concentrations have been examined for anti-noroviral activity. The reduction of norovirus > 1 log10 genome equivalents (GE) has been obtained with 1 mg/mL of Aronia melanocarpa leaf extract (AMLE), dried wine Prokupac (WPE) and Hypericum perforatum extract (HyPE). Some of MPE i.e. HyPE, Aronia melanocarpa fruit extract (AMFE) and Punica granatum (PPE) showed better activity when dissolved in 30% ethanol with 5% DMSO. All results of anti-noroviral activity of tested MPE which achieve  lt  0.5 log10 GE are considered as not effective.
PB  - Institut za proučavanje lekovitog bilja Dr Josif Pančić, Beograd
T2  - Lekovite sirovine
T1  - Antiviral activity of medicinal plants extracts against foodborne norovirus
EP  - 34
IS  - 38
SP  - 31
DO  - 10.5937/leksir1838031Z
ER  - 

@article{
author = "Živković, Ivana and Šavikin, Katarina and Zdunić, Gordana and Živković, Jelena and Bigović, Dubravka and Menković, Nebojša and Radin, Dragoslava",
year = "2018",
abstract = "Medicinal plant extracts (MPE) have a broad antimicrobial activity, including antiviral effects. In our study, eleven dry extract of ten different medicinal plant prepared with two solvents (5%, dimethyl sulfoxide (DMSO) and 30% ethanol in 5% DMSO) in different concentrations have been examined for anti-noroviral activity. The reduction of norovirus > 1 log10 genome equivalents (GE) has been obtained with 1 mg/mL of Aronia melanocarpa leaf extract (AMLE), dried wine Prokupac (WPE) and Hypericum perforatum extract (HyPE). Some of MPE i.e. HyPE, Aronia melanocarpa fruit extract (AMFE) and Punica granatum (PPE) showed better activity when dissolved in 30% ethanol with 5% DMSO. All results of anti-noroviral activity of tested MPE which achieve  lt  0.5 log10 GE are considered as not effective.",
publisher = "Institut za proučavanje lekovitog bilja Dr Josif Pančić, Beograd",
journal = "Lekovite sirovine",
title = "Antiviral activity of medicinal plants extracts against foodborne norovirus",
pages = "34-31",
number = "38",
doi = "10.5937/leksir1838031Z"
}

Živković, I., Šavikin, K., Zdunić, G., Živković, J., Bigović, D., Menković, N.,& Radin, D.. (2018). Antiviral activity of medicinal plants extracts against foodborne norovirus. in Lekovite sirovine
Institut za proučavanje lekovitog bilja Dr Josif Pančić, Beograd.(38), 31-34.
https://doi.org/10.5937/leksir1838031Z

Živković I, Šavikin K, Zdunić G, Živković J, Bigović D, Menković N, Radin D. Antiviral activity of medicinal plants extracts against foodborne norovirus. in Lekovite sirovine. 2018;(38):31-34.
doi:10.5937/leksir1838031Z .

Živković, Ivana, Šavikin, Katarina, Zdunić, Gordana, Živković, Jelena, Bigović, Dubravka, Menković, Nebojša, Radin, Dragoslava, "Antiviral activity of medicinal plants extracts against foodborne norovirus" in Lekovite sirovine, no. 38 (2018):31-34,
https://doi.org/10.5937/leksir1838031Z . .

TY  - JOUR
AU  - Jovanović, Aleksandra A.
AU  - Balanc, Bojana
AU  - Ota, Ajda
AU  - Grabnar, Pegi Ahlin
AU  - Djordjević, Verica B.
AU  - Savikin, Katarina
AU  - Bugarski, Branko
AU  - Nedović, Viktor
AU  - Ulrih, Nataša Poklar
PY  - 2018
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4666
AB  - The influence of different phospholipid types (pure phospholipids 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, POPC, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, DPPC, and one commercial phospholipid mixture, Lipoid H100), sterol types (cholesterol vs. -sitosterol), and various sterol concentrations (5-50mol%) on liposomal membrane fluidity, thermotropic properties, liposome size, zeta potential, and lipid oxidation kinetics using fluorescent lipid probe BODIPY 581/591 C-11 (4,4-difluoro-5-[4-phenyl-1,3-butadienyl]-4-bora-3a,4a-diaza-s-indacene-3-undecanoic acid) are investigated. DPPC bilayer is more rigid than POPC and phospholipids mixture membranes. Pure DPPC gives the smallest liposomes, while liposomes of Lipoid H100 have the largest diameter. Both sterols reduce membrane fluidity of all liposomes, increase absolute zeta potential, cause significant changes in particle size, and decrease phase transition temperature (T-m) and enthalpy of DPPC. POPC/-sitosterol liposomes exhibit the most significant lipid oxidation of the lipophilic probe. Along with beneficial effects of phytosterols on human health, better membrane fluidity, more favorable and stabilizing interactions with phospholipids, smaller vesicle size, and enhanced physical stability in comparison to cholesterol are some of the encouraging results for the use of -sitosterol in liposome formulations for potential application in foods, pharmaceutics, and cosmetics.Practical Applications: Adjusting the composition of liposomal membrane (lipid type, sterol type, and concentration) can be used as a tool to control membrane fluidity, permeability, and thermotropic properties, and thus predict release properties, physical, thermal, and oxidative stability. A commercial phospholipid mixture of different natural phospholipids with impurities creates less uniform liposomal membrane that is characterized by higher fluidity in comparison to DPPC. The type of phospholipid has huge influence on MLVs size. -sitosterol, which is a phytosterol with beneficial effects on human health can be used as a replacement for cholesterol in liposomal formulations, but with the following in mind: -sitosterol reduces fluidity of the phospholipid bilayer to a lesser extent than cholesterol, -sitosterol gives smaller MLVs than cholesterol, DPPC/-sitosterol SUVs are bigger than 100nm in diameter (relevant for intravenous administration), MLVs with 30mol% of -sitosterol can be considered as physically stable (unlike those with cholesterol), irrespective to the phospholipid type.
PB  - Wiley, Hoboken
T2  - European Journal of Lipid Science and Technology
T1  - Comparative Effects of Cholesterol and -Sitosterol on the Liposome Membrane Characteristics
IS  - 9
VL  - 120
DO  - 10.1002/ejlt.201800039
ER  - 

@article{
author = "Jovanović, Aleksandra A. and Balanc, Bojana and Ota, Ajda and Grabnar, Pegi Ahlin and Djordjević, Verica B. and Savikin, Katarina and Bugarski, Branko and Nedović, Viktor and Ulrih, Nataša Poklar",
year = "2018",
abstract = "The influence of different phospholipid types (pure phospholipids 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, POPC, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine, DPPC, and one commercial phospholipid mixture, Lipoid H100), sterol types (cholesterol vs. -sitosterol), and various sterol concentrations (5-50mol%) on liposomal membrane fluidity, thermotropic properties, liposome size, zeta potential, and lipid oxidation kinetics using fluorescent lipid probe BODIPY 581/591 C-11 (4,4-difluoro-5-[4-phenyl-1,3-butadienyl]-4-bora-3a,4a-diaza-s-indacene-3-undecanoic acid) are investigated. DPPC bilayer is more rigid than POPC and phospholipids mixture membranes. Pure DPPC gives the smallest liposomes, while liposomes of Lipoid H100 have the largest diameter. Both sterols reduce membrane fluidity of all liposomes, increase absolute zeta potential, cause significant changes in particle size, and decrease phase transition temperature (T-m) and enthalpy of DPPC. POPC/-sitosterol liposomes exhibit the most significant lipid oxidation of the lipophilic probe. Along with beneficial effects of phytosterols on human health, better membrane fluidity, more favorable and stabilizing interactions with phospholipids, smaller vesicle size, and enhanced physical stability in comparison to cholesterol are some of the encouraging results for the use of -sitosterol in liposome formulations for potential application in foods, pharmaceutics, and cosmetics.Practical Applications: Adjusting the composition of liposomal membrane (lipid type, sterol type, and concentration) can be used as a tool to control membrane fluidity, permeability, and thermotropic properties, and thus predict release properties, physical, thermal, and oxidative stability. A commercial phospholipid mixture of different natural phospholipids with impurities creates less uniform liposomal membrane that is characterized by higher fluidity in comparison to DPPC. The type of phospholipid has huge influence on MLVs size. -sitosterol, which is a phytosterol with beneficial effects on human health can be used as a replacement for cholesterol in liposomal formulations, but with the following in mind: -sitosterol reduces fluidity of the phospholipid bilayer to a lesser extent than cholesterol, -sitosterol gives smaller MLVs than cholesterol, DPPC/-sitosterol SUVs are bigger than 100nm in diameter (relevant for intravenous administration), MLVs with 30mol% of -sitosterol can be considered as physically stable (unlike those with cholesterol), irrespective to the phospholipid type.",
publisher = "Wiley, Hoboken",
journal = "European Journal of Lipid Science and Technology",
title = "Comparative Effects of Cholesterol and -Sitosterol on the Liposome Membrane Characteristics",
number = "9",
volume = "120",
doi = "10.1002/ejlt.201800039"
}

Jovanović, A. A., Balanc, B., Ota, A., Grabnar, P. A., Djordjević, V. B., Savikin, K., Bugarski, B., Nedović, V.,& Ulrih, N. P.. (2018). Comparative Effects of Cholesterol and -Sitosterol on the Liposome Membrane Characteristics. in European Journal of Lipid Science and Technology
Wiley, Hoboken., 120(9).
https://doi.org/10.1002/ejlt.201800039

Jovanović AA, Balanc B, Ota A, Grabnar PA, Djordjević VB, Savikin K, Bugarski B, Nedović V, Ulrih NP. Comparative Effects of Cholesterol and -Sitosterol on the Liposome Membrane Characteristics. in European Journal of Lipid Science and Technology. 2018;120(9).
doi:10.1002/ejlt.201800039 .

Jovanović, Aleksandra A., Balanc, Bojana, Ota, Ajda, Grabnar, Pegi Ahlin, Djordjević, Verica B., Savikin, Katarina, Bugarski, Branko, Nedović, Viktor, Ulrih, Nataša Poklar, "Comparative Effects of Cholesterol and -Sitosterol on the Liposome Membrane Characteristics" in European Journal of Lipid Science and Technology, 120, no. 9 (2018),
https://doi.org/10.1002/ejlt.201800039 . .

TY  - JOUR
AU  - Zivković, Jelena
AU  - Savikin, Katarina
AU  - Zdunić, Gordana
AU  - Godjevac, Dejan
AU  - Marković, Nebojša
AU  - Pržić, Zoran
AU  - Menković, Nebojša
PY  - 2016
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4083
AB  - Wine quality depends mainly on the characteristics of the grape it is made of, and one of the attributes affecting wine composition is cluster and berry morphology. The aim of this study was to represent variability of the morphological characteristics between different clones of the autochthonous grape variety Prokupac and to perform chemical evaluation of wines obtained from them. Total phenolic content was generally low and it ranged from 33.0 to 114.5 mg GAE/100 mL. Six main anthocyanin compounds including malvidin as the main anthocyanidin were detected. Malvidin 3-O-glucoside was the most abundant anthocyanin with concentration of 59.8 to 101.7 mu g/mL. Clones 43/5 and 43/4 yielded highest quality wines. According to the results, clonal selection makes a significant difference in Prokupac wine quality. On the other hand, there is a minor dependance of wine quality parameters to variation in morphological attributes of clusters and berries (bunch weight, proportion of stem, berry and seed weight, skin, pulp and seed weight per berry).
PB  - Srpsko hemijsko društvo, Beograd
T2  - JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
T1  - Influence of bunch morphology on quality of wines produced from clones of grape variety Prokupac
EP  - 896
IS  - 8
SP  - 883
VL  - 81
DO  - 10.2298/JSC151114033Z
ER  - 

@article{
author = "Zivković, Jelena and Savikin, Katarina and Zdunić, Gordana and Godjevac, Dejan and Marković, Nebojša and Pržić, Zoran and Menković, Nebojša",
year = "2016",
abstract = "Wine quality depends mainly on the characteristics of the grape it is made of, and one of the attributes affecting wine composition is cluster and berry morphology. The aim of this study was to represent variability of the morphological characteristics between different clones of the autochthonous grape variety Prokupac and to perform chemical evaluation of wines obtained from them. Total phenolic content was generally low and it ranged from 33.0 to 114.5 mg GAE/100 mL. Six main anthocyanin compounds including malvidin as the main anthocyanidin were detected. Malvidin 3-O-glucoside was the most abundant anthocyanin with concentration of 59.8 to 101.7 mu g/mL. Clones 43/5 and 43/4 yielded highest quality wines. According to the results, clonal selection makes a significant difference in Prokupac wine quality. On the other hand, there is a minor dependance of wine quality parameters to variation in morphological attributes of clusters and berries (bunch weight, proportion of stem, berry and seed weight, skin, pulp and seed weight per berry).",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "JOURNAL OF THE SERBIAN CHEMICAL SOCIETY",
title = "Influence of bunch morphology on quality of wines produced from clones of grape variety Prokupac",
pages = "896-883",
number = "8",
volume = "81",
doi = "10.2298/JSC151114033Z"
}

Zivković, J., Savikin, K., Zdunić, G., Godjevac, D., Marković, N., Pržić, Z.,& Menković, N.. (2016). Influence of bunch morphology on quality of wines produced from clones of grape variety Prokupac. in JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
Srpsko hemijsko društvo, Beograd., 81(8), 883-896.
https://doi.org/10.2298/JSC151114033Z

Zivković J, Savikin K, Zdunić G, Godjevac D, Marković N, Pržić Z, Menković N. Influence of bunch morphology on quality of wines produced from clones of grape variety Prokupac. in JOURNAL OF THE SERBIAN CHEMICAL SOCIETY. 2016;81(8):883-896.
doi:10.2298/JSC151114033Z .

Zivković, Jelena, Savikin, Katarina, Zdunić, Gordana, Godjevac, Dejan, Marković, Nebojša, Pržić, Zoran, Menković, Nebojša, "Influence of bunch morphology on quality of wines produced from clones of grape variety Prokupac" in JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 81, no. 8 (2016):883-896,
https://doi.org/10.2298/JSC151114033Z . .

TY  - JOUR
AU  - Djordjević, Boban
AU  - Savikin, Katarina
AU  - Djurović, Dejan
AU  - Veberić, Robert
AU  - Mikulić-Petkovsek, Maja
AU  - Zdunić, Gordana
AU  - Vulić, Todor
PY  - 2015
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6053
AB  - BACKGROUND: Changes of environmental factors, created under the influence of various shading nets, could significantly affect the biological characteristics of plants grown in such conditions as well as biosynthesis of primary metabolites and ascorbic acid. Five blackcurrant cultivars - 'Ben Sarek', 'Ben Nevis', 'Ben Lomond', 'Ometa' and 'aanska Crna' - were cultivated in the shade of two green polyethylene nets and exposed to direct sunlight during two experimental seasons. RESULTSIn the control treatment, all cultivars contained the highest amounts of soluble solid content and number of flower buds per shoot in both years of cultivation. The bushes exposed to direct sunlight had the highest sunburn damage to the berries and leaves, and loss of yield. The greatest yield loss caused by berry damage in the present study during the experimental period was in cultivar 'Ben Sarek': 9.0% in 2010 and 15.4% in 2011. Growing in the shade of light-green net contributed the highest content of ascorbic acid. Control bushes and those shaded by light-green net had significantly higher radical scavenging activity, with values between 1.15 and 1.22 mg mL(-1). CONCLUSIONPlants shaded by nets in both years of cultivation had lower damage to leaves and berries and percentage of loss of yield, and usage of the net would be economically advantageous to growers. Fruit of blackcurrant cultivars grown in shading conditions still represent a good source of valuable nutritive and biologically active compounds.
PB  - Wiley, Hoboken
T2  - Journal of the Science of Food and Agriculture
T1  - Biological and nutritional properties of blackcurrant berries (Ribes nigrum L.) under conditions of shading nets
EP  - 2423
IS  - 12
SP  - 2416
VL  - 95
DO  - 10.1002/jsfa.6962
ER  - 

@article{
author = "Djordjević, Boban and Savikin, Katarina and Djurović, Dejan and Veberić, Robert and Mikulić-Petkovsek, Maja and Zdunić, Gordana and Vulić, Todor",
year = "2015",
abstract = "BACKGROUND: Changes of environmental factors, created under the influence of various shading nets, could significantly affect the biological characteristics of plants grown in such conditions as well as biosynthesis of primary metabolites and ascorbic acid. Five blackcurrant cultivars - 'Ben Sarek', 'Ben Nevis', 'Ben Lomond', 'Ometa' and 'aanska Crna' - were cultivated in the shade of two green polyethylene nets and exposed to direct sunlight during two experimental seasons. RESULTSIn the control treatment, all cultivars contained the highest amounts of soluble solid content and number of flower buds per shoot in both years of cultivation. The bushes exposed to direct sunlight had the highest sunburn damage to the berries and leaves, and loss of yield. The greatest yield loss caused by berry damage in the present study during the experimental period was in cultivar 'Ben Sarek': 9.0% in 2010 and 15.4% in 2011. Growing in the shade of light-green net contributed the highest content of ascorbic acid. Control bushes and those shaded by light-green net had significantly higher radical scavenging activity, with values between 1.15 and 1.22 mg mL(-1). CONCLUSIONPlants shaded by nets in both years of cultivation had lower damage to leaves and berries and percentage of loss of yield, and usage of the net would be economically advantageous to growers. Fruit of blackcurrant cultivars grown in shading conditions still represent a good source of valuable nutritive and biologically active compounds.",
publisher = "Wiley, Hoboken",
journal = "Journal of the Science of Food and Agriculture",
title = "Biological and nutritional properties of blackcurrant berries (Ribes nigrum L.) under conditions of shading nets",
pages = "2423-2416",
number = "12",
volume = "95",
doi = "10.1002/jsfa.6962"
}

Djordjević, B., Savikin, K., Djurović, D., Veberić, R., Mikulić-Petkovsek, M., Zdunić, G.,& Vulić, T.. (2015). Biological and nutritional properties of blackcurrant berries (Ribes nigrum L.) under conditions of shading nets. in Journal of the Science of Food and Agriculture
Wiley, Hoboken., 95(12), 2416-2423.
https://doi.org/10.1002/jsfa.6962

Djordjević B, Savikin K, Djurović D, Veberić R, Mikulić-Petkovsek M, Zdunić G, Vulić T. Biological and nutritional properties of blackcurrant berries (Ribes nigrum L.) under conditions of shading nets. in Journal of the Science of Food and Agriculture. 2015;95(12):2416-2423.
doi:10.1002/jsfa.6962 .

Djordjević, Boban, Savikin, Katarina, Djurović, Dejan, Veberić, Robert, Mikulić-Petkovsek, Maja, Zdunić, Gordana, Vulić, Todor, "Biological and nutritional properties of blackcurrant berries (Ribes nigrum L.) under conditions of shading nets" in Journal of the Science of Food and Agriculture, 95, no. 12 (2015):2416-2423,
https://doi.org/10.1002/jsfa.6962 . .

TY  - JOUR
AU  - Djordjević, Boban
AU  - Savikin, Katarina
AU  - Djurović, Dejan
AU  - Veberić, Robert
AU  - Mikulić-Petkovsek, Maja
AU  - Zdunić, Gordana
AU  - Vulić, Todor
PY  - 2015
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3676
AB  - BACKGROUND: Changes of environmental factors, created under the influence of various shading nets, could significantly affect the biological characteristics of plants grown in such conditions as well as biosynthesis of primary metabolites and ascorbic acid. Five blackcurrant cultivars - 'Ben Sarek', 'Ben Nevis', 'Ben Lomond', 'Ometa' and 'aanska Crna' - were cultivated in the shade of two green polyethylene nets and exposed to direct sunlight during two experimental seasons. RESULTSIn the control treatment, all cultivars contained the highest amounts of soluble solid content and number of flower buds per shoot in both years of cultivation. The bushes exposed to direct sunlight had the highest sunburn damage to the berries and leaves, and loss of yield. The greatest yield loss caused by berry damage in the present study during the experimental period was in cultivar 'Ben Sarek': 9.0% in 2010 and 15.4% in 2011. Growing in the shade of light-green net contributed the highest content of ascorbic acid. Control bushes and those shaded by light-green net had significantly higher radical scavenging activity, with values between 1.15 and 1.22 mg mL(-1). CONCLUSIONPlants shaded by nets in both years of cultivation had lower damage to leaves and berries and percentage of loss of yield, and usage of the net would be economically advantageous to growers. Fruit of blackcurrant cultivars grown in shading conditions still represent a good source of valuable nutritive and biologically active compounds.
PB  - Wiley, Hoboken
T2  - Journal of the Science of Food and Agriculture
T1  - Biological and nutritional properties of blackcurrant berries (Ribes nigrum L.) under conditions of shading nets
EP  - 2423
IS  - 12
SP  - 2416
VL  - 95
DO  - 10.1002/jsfa.6962
ER  - 

@article{
author = "Djordjević, Boban and Savikin, Katarina and Djurović, Dejan and Veberić, Robert and Mikulić-Petkovsek, Maja and Zdunić, Gordana and Vulić, Todor",
year = "2015",
abstract = "BACKGROUND: Changes of environmental factors, created under the influence of various shading nets, could significantly affect the biological characteristics of plants grown in such conditions as well as biosynthesis of primary metabolites and ascorbic acid. Five blackcurrant cultivars - 'Ben Sarek', 'Ben Nevis', 'Ben Lomond', 'Ometa' and 'aanska Crna' - were cultivated in the shade of two green polyethylene nets and exposed to direct sunlight during two experimental seasons. RESULTSIn the control treatment, all cultivars contained the highest amounts of soluble solid content and number of flower buds per shoot in both years of cultivation. The bushes exposed to direct sunlight had the highest sunburn damage to the berries and leaves, and loss of yield. The greatest yield loss caused by berry damage in the present study during the experimental period was in cultivar 'Ben Sarek': 9.0% in 2010 and 15.4% in 2011. Growing in the shade of light-green net contributed the highest content of ascorbic acid. Control bushes and those shaded by light-green net had significantly higher radical scavenging activity, with values between 1.15 and 1.22 mg mL(-1). CONCLUSIONPlants shaded by nets in both years of cultivation had lower damage to leaves and berries and percentage of loss of yield, and usage of the net would be economically advantageous to growers. Fruit of blackcurrant cultivars grown in shading conditions still represent a good source of valuable nutritive and biologically active compounds.",
publisher = "Wiley, Hoboken",
journal = "Journal of the Science of Food and Agriculture",
title = "Biological and nutritional properties of blackcurrant berries (Ribes nigrum L.) under conditions of shading nets",
pages = "2423-2416",
number = "12",
volume = "95",
doi = "10.1002/jsfa.6962"
}

Djordjević, B., Savikin, K., Djurović, D., Veberić, R., Mikulić-Petkovsek, M., Zdunić, G.,& Vulić, T.. (2015). Biological and nutritional properties of blackcurrant berries (Ribes nigrum L.) under conditions of shading nets. in Journal of the Science of Food and Agriculture
Wiley, Hoboken., 95(12), 2416-2423.
https://doi.org/10.1002/jsfa.6962

Djordjević B, Savikin K, Djurović D, Veberić R, Mikulić-Petkovsek M, Zdunić G, Vulić T. Biological and nutritional properties of blackcurrant berries (Ribes nigrum L.) under conditions of shading nets. in Journal of the Science of Food and Agriculture. 2015;95(12):2416-2423.
doi:10.1002/jsfa.6962 .

Djordjević, Boban, Savikin, Katarina, Djurović, Dejan, Veberić, Robert, Mikulić-Petkovsek, Maja, Zdunić, Gordana, Vulić, Todor, "Biological and nutritional properties of blackcurrant berries (Ribes nigrum L.) under conditions of shading nets" in Journal of the Science of Food and Agriculture, 95, no. 12 (2015):2416-2423,
https://doi.org/10.1002/jsfa.6962 . .

TY  - JOUR
AU  - Trifković, Kata
AU  - Milasinović, Nikola
AU  - Djordjević, Verica B.
AU  - Zdunić, Gordana
AU  - Kalagasidis-Krusić, Melina T.
AU  - Knežević-Jugović, Zorica
AU  - Savikin, Katarina
AU  - Nedović, Viktor
AU  - Bugarski, Branko
PY  - 2015
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3751
AB  - Chitosan-glutaraldehyde microparticles were produced by emulsion crosslinking method to be used as drug delivery system for polyphenols from Thymus serpyllum L. aqueous extract. The effect of preparation conditions, chitosan concentration (1.5-3% w/v), and glutaraldehyde/chitosan (GA/Ch) mass ratio (0.15-1.20) on water and polyphenols transport properties was investigated. Swelling ratio of dry particles (68-230 mm) in water ranged from 280% to 530%, depending on the formulation. The decrease in swelling was observed with increased GA/Ch mass ratio (i.e. crosslinking degree) at the same chitosan concentration, or with increased chitosan concentration at the same GA/Ch mass ratio. The increase in GA/Ch mass ratio was also manifested by increased particle compactness i.e. decreased size and reduced surface roughness. The sorption capacity for polyphenols seems to be a complex interplay of swelling behaviour and interactions chitosan-glutaraldehyde-polyphenols identified by Fourier transmission infrared analysis. An increase in crystallinity of chitosan was observed upon crosslinking with glutaraldehyde and encapsulation of polyphenols, as observed by X-ray diffraction analysis. The results obtained from release kinetics of selected polyphenolic compounds (caffeic acid, rosmarinic acid, total flavonoids, and total phenol content) showed that polyphenols were released at a lower amount (2-4 times) in water, but more rapidly (45-120 min) in comparison with the release in gastric followed by intestinal simulated fluid (SGF-SIF) (120-240 min). The experimental results of the time-dependent swelling in water and polyphenols release in both, water and SGF-SIF, were analyzed with several mathematical models. The results depicted Fickian diffusion as the water transport mechanism. In the case of polyphenols, only empirical Weibull model could be suggested for describing release kinetics.
PB  - Sage Publications Ltd, London
T2  - Journal of Biomaterials Applications
T1  - Chitosan crosslinked microparticles with encapsulated polyphenols: Water sorption and release properties
EP  - 631
IS  - 5
SP  - 618
VL  - 30
DO  - 10.1177/0885328215598940
ER  - 

@article{
author = "Trifković, Kata and Milasinović, Nikola and Djordjević, Verica B. and Zdunić, Gordana and Kalagasidis-Krusić, Melina T. and Knežević-Jugović, Zorica and Savikin, Katarina and Nedović, Viktor and Bugarski, Branko",
year = "2015",
abstract = "Chitosan-glutaraldehyde microparticles were produced by emulsion crosslinking method to be used as drug delivery system for polyphenols from Thymus serpyllum L. aqueous extract. The effect of preparation conditions, chitosan concentration (1.5-3% w/v), and glutaraldehyde/chitosan (GA/Ch) mass ratio (0.15-1.20) on water and polyphenols transport properties was investigated. Swelling ratio of dry particles (68-230 mm) in water ranged from 280% to 530%, depending on the formulation. The decrease in swelling was observed with increased GA/Ch mass ratio (i.e. crosslinking degree) at the same chitosan concentration, or with increased chitosan concentration at the same GA/Ch mass ratio. The increase in GA/Ch mass ratio was also manifested by increased particle compactness i.e. decreased size and reduced surface roughness. The sorption capacity for polyphenols seems to be a complex interplay of swelling behaviour and interactions chitosan-glutaraldehyde-polyphenols identified by Fourier transmission infrared analysis. An increase in crystallinity of chitosan was observed upon crosslinking with glutaraldehyde and encapsulation of polyphenols, as observed by X-ray diffraction analysis. The results obtained from release kinetics of selected polyphenolic compounds (caffeic acid, rosmarinic acid, total flavonoids, and total phenol content) showed that polyphenols were released at a lower amount (2-4 times) in water, but more rapidly (45-120 min) in comparison with the release in gastric followed by intestinal simulated fluid (SGF-SIF) (120-240 min). The experimental results of the time-dependent swelling in water and polyphenols release in both, water and SGF-SIF, were analyzed with several mathematical models. The results depicted Fickian diffusion as the water transport mechanism. In the case of polyphenols, only empirical Weibull model could be suggested for describing release kinetics.",
publisher = "Sage Publications Ltd, London",
journal = "Journal of Biomaterials Applications",
title = "Chitosan crosslinked microparticles with encapsulated polyphenols: Water sorption and release properties",
pages = "631-618",
number = "5",
volume = "30",
doi = "10.1177/0885328215598940"
}

Trifković, K., Milasinović, N., Djordjević, V. B., Zdunić, G., Kalagasidis-Krusić, M. T., Knežević-Jugović, Z., Savikin, K., Nedović, V.,& Bugarski, B.. (2015). Chitosan crosslinked microparticles with encapsulated polyphenols: Water sorption and release properties. in Journal of Biomaterials Applications
Sage Publications Ltd, London., 30(5), 618-631.
https://doi.org/10.1177/0885328215598940

Trifković K, Milasinović N, Djordjević VB, Zdunić G, Kalagasidis-Krusić MT, Knežević-Jugović Z, Savikin K, Nedović V, Bugarski B. Chitosan crosslinked microparticles with encapsulated polyphenols: Water sorption and release properties. in Journal of Biomaterials Applications. 2015;30(5):618-631.
doi:10.1177/0885328215598940 .

Trifković, Kata, Milasinović, Nikola, Djordjević, Verica B., Zdunić, Gordana, Kalagasidis-Krusić, Melina T., Knežević-Jugović, Zorica, Savikin, Katarina, Nedović, Viktor, Bugarski, Branko, "Chitosan crosslinked microparticles with encapsulated polyphenols: Water sorption and release properties" in Journal of Biomaterials Applications, 30, no. 5 (2015):618-631,
https://doi.org/10.1177/0885328215598940 . .

TY  - JOUR
AU  - Miladinović, Bojana
AU  - Kostić, Milica
AU  - Savikin, Katarina
AU  - Djordjević, Boban
AU  - Mihajilov-Krstev, Tatjana
AU  - Zivanović, Slavoljub
AU  - Kitić, Dušanka
PY  - 2014
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3529
AB  - The aim of this article was to determine the chemical composition (anthocyanin and ascorbic acid contents, total phenols, and tannins), and the antioxidative, and antimicrobial activities of the juices and methanol extracts of 4 varieties-Tenah, Triton, Ben Sarek, and Ometa. The juices were made during 2008, 2009, and 2010 from the berries grown on the same location. Statistically significant differences were found in all the tested parameters of each variety for every year. Ometa variety exhibited the best antioxidative activity. The highest ascorbic acid value had Tenah juice from 2010 (211 mg/100 g) and Ben Sarek methanol extract (656 mg/100 g). Delphinidin-3-ruthenoside was the dominant anthocyanin in Triton, Tenah, and Ben Sarek variety during all 3 y and Ometa in 2010 where Ometa in 2008 and 2009 had slightly higher content of cyanidin-3-ruthenoside. The minimum inhibitory and microbicidal concentrations ranged from MIC/MBC(MFC) = 62.5 to 500 mg/mL for juices and 0.4 to 500 mg/mL for extracts. There was no significant difference in the effect of the juices against Gram(+) and Gram(-) bacteria. All the extracts acted in lower concentrations than juices. Practical Application Data contained in this article provide an insight into the effects the weather condition has on the content of the bioactive compounds in genetically different types of black currants, during the 3-y observation period. This article is relevant to the commercial application of black currants-based dietary supplements.
PB  - Wiley, Hoboken
T2  - Journal of Food Science
T1  - Chemical Profile and Antioxidative and Antimicrobial Activity of Juices and Extracts of 4 Black Currants Varieties (Ribes nigrum L.)
EP  - C309
IS  - 3
SP  - C301
VL  - 79
DO  - 10.1111/1750-3841.12364
ER  - 

@article{
author = "Miladinović, Bojana and Kostić, Milica and Savikin, Katarina and Djordjević, Boban and Mihajilov-Krstev, Tatjana and Zivanović, Slavoljub and Kitić, Dušanka",
year = "2014",
abstract = "The aim of this article was to determine the chemical composition (anthocyanin and ascorbic acid contents, total phenols, and tannins), and the antioxidative, and antimicrobial activities of the juices and methanol extracts of 4 varieties-Tenah, Triton, Ben Sarek, and Ometa. The juices were made during 2008, 2009, and 2010 from the berries grown on the same location. Statistically significant differences were found in all the tested parameters of each variety for every year. Ometa variety exhibited the best antioxidative activity. The highest ascorbic acid value had Tenah juice from 2010 (211 mg/100 g) and Ben Sarek methanol extract (656 mg/100 g). Delphinidin-3-ruthenoside was the dominant anthocyanin in Triton, Tenah, and Ben Sarek variety during all 3 y and Ometa in 2010 where Ometa in 2008 and 2009 had slightly higher content of cyanidin-3-ruthenoside. The minimum inhibitory and microbicidal concentrations ranged from MIC/MBC(MFC) = 62.5 to 500 mg/mL for juices and 0.4 to 500 mg/mL for extracts. There was no significant difference in the effect of the juices against Gram(+) and Gram(-) bacteria. All the extracts acted in lower concentrations than juices. Practical Application Data contained in this article provide an insight into the effects the weather condition has on the content of the bioactive compounds in genetically different types of black currants, during the 3-y observation period. This article is relevant to the commercial application of black currants-based dietary supplements.",
publisher = "Wiley, Hoboken",
journal = "Journal of Food Science",
title = "Chemical Profile and Antioxidative and Antimicrobial Activity of Juices and Extracts of 4 Black Currants Varieties (Ribes nigrum L.)",
pages = "C309-C301",
number = "3",
volume = "79",
doi = "10.1111/1750-3841.12364"
}

Miladinović, B., Kostić, M., Savikin, K., Djordjević, B., Mihajilov-Krstev, T., Zivanović, S.,& Kitić, D.. (2014). Chemical Profile and Antioxidative and Antimicrobial Activity of Juices and Extracts of 4 Black Currants Varieties (Ribes nigrum L.). in Journal of Food Science
Wiley, Hoboken., 79(3), C301-C309.
https://doi.org/10.1111/1750-3841.12364

Miladinović B, Kostić M, Savikin K, Djordjević B, Mihajilov-Krstev T, Zivanović S, Kitić D. Chemical Profile and Antioxidative and Antimicrobial Activity of Juices and Extracts of 4 Black Currants Varieties (Ribes nigrum L.). in Journal of Food Science. 2014;79(3):C301-C309.
doi:10.1111/1750-3841.12364 .

Miladinović, Bojana, Kostić, Milica, Savikin, Katarina, Djordjević, Boban, Mihajilov-Krstev, Tatjana, Zivanović, Slavoljub, Kitić, Dušanka, "Chemical Profile and Antioxidative and Antimicrobial Activity of Juices and Extracts of 4 Black Currants Varieties (Ribes nigrum L.)" in Journal of Food Science, 79, no. 3 (2014):C301-C309,
https://doi.org/10.1111/1750-3841.12364 . .

TY  - JOUR
AU  - Djordjević, Boban
AU  - Rakonjac, Vera
AU  - Fotirić-Akšić, Milica
AU  - Savikin, Katarina
AU  - Vulić, Todor
PY  - 2014
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3499
AB  - Descriptive and multivariate statistic analysis was used to determine phenotypical diversity among 29 European currant cultivars. Variation in 39 traits related to phenology, vegetative and reproductive potential, fruit quality, content of antioxidants in berries, and oils in seeds indicated a high diversity of currant cultivars. PCA analysis showed high discrimination capabilities of variables measured. The most important traits for cultivars grouping were related to yield efficiency, fruit quality, and content of bioactive compounds. These traits should be taken into account in the further currant cultivars characterization and analysis of breeding material. Both, cluster (CA) and principal component analysis (PCA), showed an adequate grouping of cultivars in two groups of cultivars, one consisting of black and the second group comprising the red and white currant cultivars. By PCA, within each of these two major groups dispersed layout of cultivars was obtained, while using CA a larger number of sub-clusters was separated indicating phenotypic and thus genotypic heterogeneity of studied cultivars. Great diversity in this currant collection showed its good potential for fresh and processing usage, and further breeding programs.
PB  - Elsevier, Amsterdam
T2  - Scientia Horticulturae
T1  - Pomological and biochemical characterization of European currant berry (Ribes sp.) cultivars
EP  - 162
SP  - 156
VL  - 165
DO  - 10.1016/j.scienta.2013.11.014
ER  - 

@article{
author = "Djordjević, Boban and Rakonjac, Vera and Fotirić-Akšić, Milica and Savikin, Katarina and Vulić, Todor",
year = "2014",
abstract = "Descriptive and multivariate statistic analysis was used to determine phenotypical diversity among 29 European currant cultivars. Variation in 39 traits related to phenology, vegetative and reproductive potential, fruit quality, content of antioxidants in berries, and oils in seeds indicated a high diversity of currant cultivars. PCA analysis showed high discrimination capabilities of variables measured. The most important traits for cultivars grouping were related to yield efficiency, fruit quality, and content of bioactive compounds. These traits should be taken into account in the further currant cultivars characterization and analysis of breeding material. Both, cluster (CA) and principal component analysis (PCA), showed an adequate grouping of cultivars in two groups of cultivars, one consisting of black and the second group comprising the red and white currant cultivars. By PCA, within each of these two major groups dispersed layout of cultivars was obtained, while using CA a larger number of sub-clusters was separated indicating phenotypic and thus genotypic heterogeneity of studied cultivars. Great diversity in this currant collection showed its good potential for fresh and processing usage, and further breeding programs.",
publisher = "Elsevier, Amsterdam",
journal = "Scientia Horticulturae",
title = "Pomological and biochemical characterization of European currant berry (Ribes sp.) cultivars",
pages = "162-156",
volume = "165",
doi = "10.1016/j.scienta.2013.11.014"
}

Djordjević, B., Rakonjac, V., Fotirić-Akšić, M., Savikin, K.,& Vulić, T.. (2014). Pomological and biochemical characterization of European currant berry (Ribes sp.) cultivars. in Scientia Horticulturae
Elsevier, Amsterdam., 165, 156-162.
https://doi.org/10.1016/j.scienta.2013.11.014

Djordjević B, Rakonjac V, Fotirić-Akšić M, Savikin K, Vulić T. Pomological and biochemical characterization of European currant berry (Ribes sp.) cultivars. in Scientia Horticulturae. 2014;165:156-162.
doi:10.1016/j.scienta.2013.11.014 .

Djordjević, Boban, Rakonjac, Vera, Fotirić-Akšić, Milica, Savikin, Katarina, Vulić, Todor, "Pomological and biochemical characterization of European currant berry (Ribes sp.) cultivars" in Scientia Horticulturae, 165 (2014):156-162,
https://doi.org/10.1016/j.scienta.2013.11.014 . .

TY  - JOUR
AU  - Savikin, Katarina
AU  - Zivković, Jelena
AU  - Zdunić, Gordana
AU  - Godjevac, Dejan
AU  - Djordjević, Boban
AU  - Dojčinović, Biljana
AU  - Djordjević, Neda
PY  - 2014
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3456
AB  - Some primary and secondary metabolites, as well as mineral nutrients in pulp, peel and juice obtained from four Serbian indigenous apple cultivars (Kozara, Kolacara, Budimka and.Sumatovka) collected at two different developmental stages were studied. With advanced maturation soluble solids content, total and reducing sugars increased, while L-ascorbic acid content and titratable acidity decreased. Thirteen phenolic compounds were quantified using LC-MS/MS. The total phenolic content (TPC) ranged from 9.37 to 1440 mg/100 g fw, and 0.83 to 7.84 mg/100 g fw in peel and pulp samples, respectively. Quercetin derivatives were the major detected polyphenolic group. Majority of determined phenolic compounds were influenced by cultivar and the best sources were cultivars Kolgara and Budimka. The content of flavonols (with the exception of quercitrin) varied significantly depending on maturity at harvest. With regard to mineral analysis, K was the most abundant ranging from 104 to 158 mg/100 g fw in peel, 74.4 to 93.3 mg/100 g fw in pulp, and 77.1 to 91.5 mg/100 g fw in juice samples. Obtained results provide detailed information on nutritional potential and chemical composition of tested apple cultivars and thereby could encourage their wider cultivation and consumption
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Journal of Food Composition and Analysis
T1  - Phenolic and mineral profiles of four Balkan indigenous apple cultivars monitored at two different maturity stages
EP  - 111
IS  - 2
SP  - 101
VL  - 35
DO  - 10.1016/j.jfca.2014.05.004
ER  - 

@article{
author = "Savikin, Katarina and Zivković, Jelena and Zdunić, Gordana and Godjevac, Dejan and Djordjević, Boban and Dojčinović, Biljana and Djordjević, Neda",
year = "2014",
abstract = "Some primary and secondary metabolites, as well as mineral nutrients in pulp, peel and juice obtained from four Serbian indigenous apple cultivars (Kozara, Kolacara, Budimka and.Sumatovka) collected at two different developmental stages were studied. With advanced maturation soluble solids content, total and reducing sugars increased, while L-ascorbic acid content and titratable acidity decreased. Thirteen phenolic compounds were quantified using LC-MS/MS. The total phenolic content (TPC) ranged from 9.37 to 1440 mg/100 g fw, and 0.83 to 7.84 mg/100 g fw in peel and pulp samples, respectively. Quercetin derivatives were the major detected polyphenolic group. Majority of determined phenolic compounds were influenced by cultivar and the best sources were cultivars Kolgara and Budimka. The content of flavonols (with the exception of quercitrin) varied significantly depending on maturity at harvest. With regard to mineral analysis, K was the most abundant ranging from 104 to 158 mg/100 g fw in peel, 74.4 to 93.3 mg/100 g fw in pulp, and 77.1 to 91.5 mg/100 g fw in juice samples. Obtained results provide detailed information on nutritional potential and chemical composition of tested apple cultivars and thereby could encourage their wider cultivation and consumption",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Journal of Food Composition and Analysis",
title = "Phenolic and mineral profiles of four Balkan indigenous apple cultivars monitored at two different maturity stages",
pages = "111-101",
number = "2",
volume = "35",
doi = "10.1016/j.jfca.2014.05.004"
}

Savikin, K., Zivković, J., Zdunić, G., Godjevac, D., Djordjević, B., Dojčinović, B.,& Djordjević, N.. (2014). Phenolic and mineral profiles of four Balkan indigenous apple cultivars monitored at two different maturity stages. in Journal of Food Composition and Analysis
Academic Press Inc Elsevier Science, San Diego., 35(2), 101-111.
https://doi.org/10.1016/j.jfca.2014.05.004

Savikin K, Zivković J, Zdunić G, Godjevac D, Djordjević B, Dojčinović B, Djordjević N. Phenolic and mineral profiles of four Balkan indigenous apple cultivars monitored at two different maturity stages. in Journal of Food Composition and Analysis. 2014;35(2):101-111.
doi:10.1016/j.jfca.2014.05.004 .

Savikin, Katarina, Zivković, Jelena, Zdunić, Gordana, Godjevac, Dejan, Djordjević, Boban, Dojčinović, Biljana, Djordjević, Neda, "Phenolic and mineral profiles of four Balkan indigenous apple cultivars monitored at two different maturity stages" in Journal of Food Composition and Analysis, 35, no. 2 (2014):101-111,
https://doi.org/10.1016/j.jfca.2014.05.004 . .

TY  - JOUR
AU  - Djordjević, Boban
AU  - Pljevljakusić, Dejan
AU  - Savikin, Katarina
AU  - Stević, Tatjana R.
AU  - Bigović, Dubravka
PY  - 2014
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3401
AB  - Dormant buds are recognized as valuable side product of the blackcurrant cultivation. Four blackcurrant varieties cultivated in Serbia, i.e., Ben Sarek, Ometa, Ben Lomond, and Ben Nevis, were evaluated for the content, chemical composition, and antimicrobial activity of their bud essential oils. The oil yields of buds harvested during two different growth periods ranged from 1.2-2.0%, and the variety Ometa had the highest yield among the tested varieties. GC-FID and GC/MS analysis of the oils allowed the identification of eight main components, i.e., -pinene (1.6-5.4%), sabinene (1.9-38.4%), -car-3-ene (13.0-50.7%), -phellandrene (2.9-18.0%), terpinolene (6.6-11.9%), terpinen-4-ol (0.9-6.6%), -caryophyllene (3.8-10.4%), and -humulene (0.2-4.1%). In addition, the similarity degree of the essential-oil compositions of buds harvested from the upper and lower parts of the shrubs was investigated by hierarchical clustering. All essential oils originating from the same genotype were grouped in the same cluster, indicating the reliability of essential oils as chemotaxonomic markers. For more detailed chemotaxonomic investigations, the three compounds with the greatest variance were chosen, i.e., sabinene, -car-3-ene, and -phellandrene, which proved to be efficient for the variety distinction. Factor analysis showed that the essential-oil composition as chemotaxonomic marker in blackcurrants was more reliable for variety Ben Sarek than for variety Ben Nevis. Moreover, it was demonstrated that the essential oils had very strong inhibitory activity against all tested microorganisms. Fungi were more sensitive than bacteria; indeed their growth was completely inhibited at much lower concentrations. In comparison to commercial antibiotics, significantly lower concentrations of the oils were necessary for the complete inhibition of fungal growth.
PB  - Wiley-V C H Verlag Gmbh, Weinheim
T2  - Chemistry & Biodiversity
T1  - Essential Oil from Blackcurrant Buds as Chemotaxonomy Marker and Antimicrobial Agent
EP  - 1240
IS  - 8
SP  - 1228
VL  - 11
DO  - 10.1002/cbdv.201400039
ER  - 

@article{
author = "Djordjević, Boban and Pljevljakusić, Dejan and Savikin, Katarina and Stević, Tatjana R. and Bigović, Dubravka",
year = "2014",
abstract = "Dormant buds are recognized as valuable side product of the blackcurrant cultivation. Four blackcurrant varieties cultivated in Serbia, i.e., Ben Sarek, Ometa, Ben Lomond, and Ben Nevis, were evaluated for the content, chemical composition, and antimicrobial activity of their bud essential oils. The oil yields of buds harvested during two different growth periods ranged from 1.2-2.0%, and the variety Ometa had the highest yield among the tested varieties. GC-FID and GC/MS analysis of the oils allowed the identification of eight main components, i.e., -pinene (1.6-5.4%), sabinene (1.9-38.4%), -car-3-ene (13.0-50.7%), -phellandrene (2.9-18.0%), terpinolene (6.6-11.9%), terpinen-4-ol (0.9-6.6%), -caryophyllene (3.8-10.4%), and -humulene (0.2-4.1%). In addition, the similarity degree of the essential-oil compositions of buds harvested from the upper and lower parts of the shrubs was investigated by hierarchical clustering. All essential oils originating from the same genotype were grouped in the same cluster, indicating the reliability of essential oils as chemotaxonomic markers. For more detailed chemotaxonomic investigations, the three compounds with the greatest variance were chosen, i.e., sabinene, -car-3-ene, and -phellandrene, which proved to be efficient for the variety distinction. Factor analysis showed that the essential-oil composition as chemotaxonomic marker in blackcurrants was more reliable for variety Ben Sarek than for variety Ben Nevis. Moreover, it was demonstrated that the essential oils had very strong inhibitory activity against all tested microorganisms. Fungi were more sensitive than bacteria; indeed their growth was completely inhibited at much lower concentrations. In comparison to commercial antibiotics, significantly lower concentrations of the oils were necessary for the complete inhibition of fungal growth.",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "Chemistry & Biodiversity",
title = "Essential Oil from Blackcurrant Buds as Chemotaxonomy Marker and Antimicrobial Agent",
pages = "1240-1228",
number = "8",
volume = "11",
doi = "10.1002/cbdv.201400039"
}

Djordjević, B., Pljevljakusić, D., Savikin, K., Stević, T. R.,& Bigović, D.. (2014). Essential Oil from Blackcurrant Buds as Chemotaxonomy Marker and Antimicrobial Agent. in Chemistry & Biodiversity
Wiley-V C H Verlag Gmbh, Weinheim., 11(8), 1228-1240.
https://doi.org/10.1002/cbdv.201400039

Djordjević B, Pljevljakusić D, Savikin K, Stević TR, Bigović D. Essential Oil from Blackcurrant Buds as Chemotaxonomy Marker and Antimicrobial Agent. in Chemistry & Biodiversity. 2014;11(8):1228-1240.
doi:10.1002/cbdv.201400039 .

Djordjević, Boban, Pljevljakusić, Dejan, Savikin, Katarina, Stević, Tatjana R., Bigović, Dubravka, "Essential Oil from Blackcurrant Buds as Chemotaxonomy Marker and Antimicrobial Agent" in Chemistry & Biodiversity, 11, no. 8 (2014):1228-1240,
https://doi.org/10.1002/cbdv.201400039 . .

TY  - JOUR
AU  - Savikin, Katarina
AU  - Mikulić-Petkovsek, Maja
AU  - Djordjević, Boban
AU  - Zdunić, Gordana
AU  - Janković, Teodora
AU  - Djurović, Dejan
AU  - Veberić, Robert
PY  - 2013
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3317
AB  - Changes of environmental factors, created under influence of various shading nets, could significantly affect some pomological and organoleptic characteristics of plants grown in such conditions as well as biosynthesis of phenolic compounds. Five black currant cultivars Ben Sarek, Ben Nevis, Ben Lomond, Ometa, and Cacanska crna were cultivated either in the shade of green polyethylene nets or exposed to direct sunlight during two experimental seasons. All berries in the control treatment (without shading nets) contained higher amounts of total phenolics in both experimental seasons: 474-520 mg GAE/100 g in 2010, and in 2011 it ranged from 401 to 501 mg GAE/100 g. Similar but less expressed trend was noticed regarding anthocyanins content. Growing in shade generally led to a lower content of flavonoid, phenolic acid and anthocyanin compounds, determined by HPLC/MS. Despite the reduction of phenolic compounds content, all tested varieties expressed significant radical scavenging activity against DPPH radical, and differences in antiradical activity were statistically significant only between varieties.
PB  - Elsevier, Amsterdam
T2  - Scientia Horticulturae
T1  - Influence of shading net on polyphenol profile and radical scavenging activity in different varieties of black currant berries
EP  - 28
SP  - 20
VL  - 160
DO  - 10.1016/j.scienta.2013.05.007
ER  - 

@article{
author = "Savikin, Katarina and Mikulić-Petkovsek, Maja and Djordjević, Boban and Zdunić, Gordana and Janković, Teodora and Djurović, Dejan and Veberić, Robert",
year = "2013",
abstract = "Changes of environmental factors, created under influence of various shading nets, could significantly affect some pomological and organoleptic characteristics of plants grown in such conditions as well as biosynthesis of phenolic compounds. Five black currant cultivars Ben Sarek, Ben Nevis, Ben Lomond, Ometa, and Cacanska crna were cultivated either in the shade of green polyethylene nets or exposed to direct sunlight during two experimental seasons. All berries in the control treatment (without shading nets) contained higher amounts of total phenolics in both experimental seasons: 474-520 mg GAE/100 g in 2010, and in 2011 it ranged from 401 to 501 mg GAE/100 g. Similar but less expressed trend was noticed regarding anthocyanins content. Growing in shade generally led to a lower content of flavonoid, phenolic acid and anthocyanin compounds, determined by HPLC/MS. Despite the reduction of phenolic compounds content, all tested varieties expressed significant radical scavenging activity against DPPH radical, and differences in antiradical activity were statistically significant only between varieties.",
publisher = "Elsevier, Amsterdam",
journal = "Scientia Horticulturae",
title = "Influence of shading net on polyphenol profile and radical scavenging activity in different varieties of black currant berries",
pages = "28-20",
volume = "160",
doi = "10.1016/j.scienta.2013.05.007"
}

Savikin, K., Mikulić-Petkovsek, M., Djordjević, B., Zdunić, G., Janković, T., Djurović, D.,& Veberić, R.. (2013). Influence of shading net on polyphenol profile and radical scavenging activity in different varieties of black currant berries. in Scientia Horticulturae
Elsevier, Amsterdam., 160, 20-28.
https://doi.org/10.1016/j.scienta.2013.05.007

Savikin K, Mikulić-Petkovsek M, Djordjević B, Zdunić G, Janković T, Djurović D, Veberić R. Influence of shading net on polyphenol profile and radical scavenging activity in different varieties of black currant berries. in Scientia Horticulturae. 2013;160:20-28.
doi:10.1016/j.scienta.2013.05.007 .

Savikin, Katarina, Mikulić-Petkovsek, Maja, Djordjević, Boban, Zdunić, Gordana, Janković, Teodora, Djurović, Dejan, Veberić, Robert, "Influence of shading net on polyphenol profile and radical scavenging activity in different varieties of black currant berries" in Scientia Horticulturae, 160 (2013):20-28,
https://doi.org/10.1016/j.scienta.2013.05.007 . .

TY  - JOUR
AU  - Djordjević, Boban
AU  - Savikin, Katarina
AU  - Zdunić, Gordana
AU  - Janković, Teodora
AU  - Vulić, Todor
AU  - Pljevljakusić, Dejan
AU  - Oparnica, Čedo
PY  - 2013
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3301
AB  - Thirteen black currant varieties (Ribes nigrum L.) cultured in Serbia were characterized for their pomological properties and chemical composition (total phenolics, total anthocyanins, anthocyanin aglycones, sugars, and vitamin C). The average amount of vitamin C varied from 122.4 to 193.2 mg/100 g fresh weight (FW), while concentration of invert sugars ranged from 6.3% to 11.1%. The highest amounts of total phenolics and anthocyanins were detected in variety Ometa (278.9 mg of gallic acid equivalents per 100 g of FW [mg GAE/100 g FW] and 135.4 mg/100 g, respectively). Quantitative analyses of anthocyanin aglycones in berries were performed using high-performance liquid chromatography, and delphinidin was found to be dominant compound in 11 varieties. Total phenolics and anthocyanins contents decreased during the processing of berry fruits to juices, and the reduction of anthocyanins was more pronounced, 12%-80%. The radical scavenging activity of black currant juices was investigated by 1,1-diphenyl-2-picrylhydrazyl, and the IC50 value ranged from 1.9 to 4.0 mg/mL. Our results also showed that freezing as a way of preservation and storage could save important phytochemicals and health benefits of berries and berry juices. The amount of total phenolics in berries increased during 1 year of storage by 46.09%-171.76% and in juices by even 107.58%, while the amount of total anthocyanins in berries and juices decrease by 5.63%-52.76% and 13.04%-36.82%, respectively.
PB  - Mary Ann Liebert, Inc, New Rochelle
T2  - Journal of Medicinal Food
T1  - Biochemical Properties of the Fresh and Frozen Black Currants and Juices
EP  - 81
IS  - 1
SP  - 73
VL  - 16
DO  - 10.1089/jmf.2011.0256
ER  - 

@article{
author = "Djordjević, Boban and Savikin, Katarina and Zdunić, Gordana and Janković, Teodora and Vulić, Todor and Pljevljakusić, Dejan and Oparnica, Čedo",
year = "2013",
abstract = "Thirteen black currant varieties (Ribes nigrum L.) cultured in Serbia were characterized for their pomological properties and chemical composition (total phenolics, total anthocyanins, anthocyanin aglycones, sugars, and vitamin C). The average amount of vitamin C varied from 122.4 to 193.2 mg/100 g fresh weight (FW), while concentration of invert sugars ranged from 6.3% to 11.1%. The highest amounts of total phenolics and anthocyanins were detected in variety Ometa (278.9 mg of gallic acid equivalents per 100 g of FW [mg GAE/100 g FW] and 135.4 mg/100 g, respectively). Quantitative analyses of anthocyanin aglycones in berries were performed using high-performance liquid chromatography, and delphinidin was found to be dominant compound in 11 varieties. Total phenolics and anthocyanins contents decreased during the processing of berry fruits to juices, and the reduction of anthocyanins was more pronounced, 12%-80%. The radical scavenging activity of black currant juices was investigated by 1,1-diphenyl-2-picrylhydrazyl, and the IC50 value ranged from 1.9 to 4.0 mg/mL. Our results also showed that freezing as a way of preservation and storage could save important phytochemicals and health benefits of berries and berry juices. The amount of total phenolics in berries increased during 1 year of storage by 46.09%-171.76% and in juices by even 107.58%, while the amount of total anthocyanins in berries and juices decrease by 5.63%-52.76% and 13.04%-36.82%, respectively.",
publisher = "Mary Ann Liebert, Inc, New Rochelle",
journal = "Journal of Medicinal Food",
title = "Biochemical Properties of the Fresh and Frozen Black Currants and Juices",
pages = "81-73",
number = "1",
volume = "16",
doi = "10.1089/jmf.2011.0256"
}

Djordjević, B., Savikin, K., Zdunić, G., Janković, T., Vulić, T., Pljevljakusić, D.,& Oparnica, Č.. (2013). Biochemical Properties of the Fresh and Frozen Black Currants and Juices. in Journal of Medicinal Food
Mary Ann Liebert, Inc, New Rochelle., 16(1), 73-81.
https://doi.org/10.1089/jmf.2011.0256

Djordjević B, Savikin K, Zdunić G, Janković T, Vulić T, Pljevljakusić D, Oparnica Č. Biochemical Properties of the Fresh and Frozen Black Currants and Juices. in Journal of Medicinal Food. 2013;16(1):73-81.
doi:10.1089/jmf.2011.0256 .

Djordjević, Boban, Savikin, Katarina, Zdunić, Gordana, Janković, Teodora, Vulić, Todor, Pljevljakusić, Dejan, Oparnica, Čedo, "Biochemical Properties of the Fresh and Frozen Black Currants and Juices" in Journal of Medicinal Food, 16, no. 1 (2013):73-81,
https://doi.org/10.1089/jmf.2011.0256 . .

TY  - JOUR
AU  - Savikin, Katarina
AU  - Djordjević, Boban
AU  - Ristić, Mihailo S.
AU  - Krivokuća-Djokić, Dragana
AU  - Pljevljakusić, Dejan
AU  - Vulić, Todor
PY  - 2013
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3300
AB  - Currant seeds, a by-product of juice production, are recognized as a valuable source of oil rich in polyunsaturated fatty acids. We have evaluated 28 currant varieties for their oil content and fatty-acid composition. The oil content in the seeds ranged from 18.227.7%, and no statistical difference between varieties of different fruit color were recorded. Furthermore, the estimated oil yields in the field production ranged from 26.4212.4 kg/ha. The GC and GC/MS chemical profiles of the seed oils extracted from all examined varieties were common for currants. Linoleic acid (LA) was the major component, with contents ranging from 32.746.9% of total fatty acids, followed by a-linolenic acid (ALA; 2.932.0 %), oleic acid (OA; 9.819.9%), ?-linolenic acid (GLA; 3.318.5%), palmitic acid (PA; 4.48.1%), stearidonic acid (SDA; 2.24.7%), and stearic acid (SA; 1.22.4%). Quantitative differences in the fatty-acid profiles between varieties of different fruit color were observed. Blackcurrant varieties showed significantly higher contents of LA, GLA, and PA than red and white currant varieties, whereas significantly higher amounts of ALA and OL were detected in the red and white varieties. Cluster analysis based on the chemical oil profiles joined the blackcurrants in one group, while most of the red and white cultivars joined in a second group at the same linkage distance.
PB  - Wiley-V C H Verlag Gmbh, Weinheim
T2  - Chemistry & Biodiversity
T1  - Variation in the Fatty-Acid Content in Seeds of Various Black, Red, and White Currant Varieties
EP  - 165
IS  - 1
SP  - 157
VL  - 10
DO  - 10.1002/cbdv.201200223
ER  - 

@article{
author = "Savikin, Katarina and Djordjević, Boban and Ristić, Mihailo S. and Krivokuća-Djokić, Dragana and Pljevljakusić, Dejan and Vulić, Todor",
year = "2013",
abstract = "Currant seeds, a by-product of juice production, are recognized as a valuable source of oil rich in polyunsaturated fatty acids. We have evaluated 28 currant varieties for their oil content and fatty-acid composition. The oil content in the seeds ranged from 18.227.7%, and no statistical difference between varieties of different fruit color were recorded. Furthermore, the estimated oil yields in the field production ranged from 26.4212.4 kg/ha. The GC and GC/MS chemical profiles of the seed oils extracted from all examined varieties were common for currants. Linoleic acid (LA) was the major component, with contents ranging from 32.746.9% of total fatty acids, followed by a-linolenic acid (ALA; 2.932.0 %), oleic acid (OA; 9.819.9%), ?-linolenic acid (GLA; 3.318.5%), palmitic acid (PA; 4.48.1%), stearidonic acid (SDA; 2.24.7%), and stearic acid (SA; 1.22.4%). Quantitative differences in the fatty-acid profiles between varieties of different fruit color were observed. Blackcurrant varieties showed significantly higher contents of LA, GLA, and PA than red and white currant varieties, whereas significantly higher amounts of ALA and OL were detected in the red and white varieties. Cluster analysis based on the chemical oil profiles joined the blackcurrants in one group, while most of the red and white cultivars joined in a second group at the same linkage distance.",
publisher = "Wiley-V C H Verlag Gmbh, Weinheim",
journal = "Chemistry & Biodiversity",
title = "Variation in the Fatty-Acid Content in Seeds of Various Black, Red, and White Currant Varieties",
pages = "165-157",
number = "1",
volume = "10",
doi = "10.1002/cbdv.201200223"
}

Savikin, K., Djordjević, B., Ristić, M. S., Krivokuća-Djokić, D., Pljevljakusić, D.,& Vulić, T.. (2013). Variation in the Fatty-Acid Content in Seeds of Various Black, Red, and White Currant Varieties. in Chemistry & Biodiversity
Wiley-V C H Verlag Gmbh, Weinheim., 10(1), 157-165.
https://doi.org/10.1002/cbdv.201200223

Savikin K, Djordjević B, Ristić MS, Krivokuća-Djokić D, Pljevljakusić D, Vulić T. Variation in the Fatty-Acid Content in Seeds of Various Black, Red, and White Currant Varieties. in Chemistry & Biodiversity. 2013;10(1):157-165.
doi:10.1002/cbdv.201200223 .

Savikin, Katarina, Djordjević, Boban, Ristić, Mihailo S., Krivokuća-Djokić, Dragana, Pljevljakusić, Dejan, Vulić, Todor, "Variation in the Fatty-Acid Content in Seeds of Various Black, Red, and White Currant Varieties" in Chemistry & Biodiversity, 10, no. 1 (2013):157-165,
https://doi.org/10.1002/cbdv.201200223 . .

TY  - CONF
AU  - Djordjević, Boban
AU  - Vulić, Todor
AU  - Oparnica, Čedo
AU  - Savikin, Katarina
AU  - Janković, Teodora
AU  - Zdunić, Gordana
AU  - Zec, Gordan
PY  - 2012
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/2831
AB  - This paper presents the results of research conducted on five cultivars of white currant ('Primus', 'White Champagne', 'Witte aus Juteborg', 'Witte Parel' and 'Viktoria'), in the 2007-2009. In addition to biological and production characteristics, indicators of dietary-therapeutic values of the observed cultivars fruits were examined too. The results showed that 'Primus' and 'Victoria' cultivars have significantly higher production value than other cultivars, which recommends them for further expansion in similar agro-ecological conditions. After one year of storage at temperature of -18 degrees C, content of total phenolics in the fruits was examined, while the antiradical activity was tested in the corresponding juices. Cultivar 'Primus' significantly differs in both its total phenolic content and antiradical activity.
C3  - Acta Horticulturae
T1  - Biological and Biochemical Properties of White Currant (Ribes rubrum L.) Cultivars
EP  - 426
SP  - 423
VL  - 946
DO  - 10.17660/ActaHortic.2012.946.70
ER  - 

@conference{
author = "Djordjević, Boban and Vulić, Todor and Oparnica, Čedo and Savikin, Katarina and Janković, Teodora and Zdunić, Gordana and Zec, Gordan",
year = "2012",
abstract = "This paper presents the results of research conducted on five cultivars of white currant ('Primus', 'White Champagne', 'Witte aus Juteborg', 'Witte Parel' and 'Viktoria'), in the 2007-2009. In addition to biological and production characteristics, indicators of dietary-therapeutic values of the observed cultivars fruits were examined too. The results showed that 'Primus' and 'Victoria' cultivars have significantly higher production value than other cultivars, which recommends them for further expansion in similar agro-ecological conditions. After one year of storage at temperature of -18 degrees C, content of total phenolics in the fruits was examined, while the antiradical activity was tested in the corresponding juices. Cultivar 'Primus' significantly differs in both its total phenolic content and antiradical activity.",
journal = "Acta Horticulturae",
title = "Biological and Biochemical Properties of White Currant (Ribes rubrum L.) Cultivars",
pages = "426-423",
volume = "946",
doi = "10.17660/ActaHortic.2012.946.70"
}

Djordjević, B., Vulić, T., Oparnica, Č., Savikin, K., Janković, T., Zdunić, G.,& Zec, G.. (2012). Biological and Biochemical Properties of White Currant (Ribes rubrum L.) Cultivars. in Acta Horticulturae, 946, 423-426.
https://doi.org/10.17660/ActaHortic.2012.946.70

Djordjević B, Vulić T, Oparnica Č, Savikin K, Janković T, Zdunić G, Zec G. Biological and Biochemical Properties of White Currant (Ribes rubrum L.) Cultivars. in Acta Horticulturae. 2012;946:423-426.
doi:10.17660/ActaHortic.2012.946.70 .

Djordjević, Boban, Vulić, Todor, Oparnica, Čedo, Savikin, Katarina, Janković, Teodora, Zdunić, Gordana, Zec, Gordan, "Biological and Biochemical Properties of White Currant (Ribes rubrum L.) Cultivars" in Acta Horticulturae, 946 (2012):423-426,
https://doi.org/10.17660/ActaHortic.2012.946.70 . .

TY  - JOUR
AU  - Djordjević, Boban
AU  - Savikin, Katarina
AU  - Zdunić, Gordana
AU  - Janković, Teodora
AU  - Vulić, Todor
AU  - Oparnica, Čedo
AU  - Radivojević, Dragan
PY  - 2010
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/2388
AB  - Eleven red currant varieties (Ribes rubrum L.) cultured in Serbia were evaluated for some of their biochemical properties such as total phenolics, anthocyanins, ascorbic acid, invert sugar, soluble solid content, and acidity. The average amount of ascorbic acid varied from 50.5-71.6 mg/100 g FW, while concentration of invert sugars ranged from 6.0%-9.0%. The highest amounts of total phenolics and anthocyanins were detected in variety Redpoll (153.4 mg GAE/100 g FW and 19.3 mg/100 g, respectively). Red currants were processed to juice, and the phenolic and anthocyanin contents changed as a result of processing. Berries and juices were long-term stored at -18 A degrees C and changes in phytochemicals were monitored. In berries, storage caused the decrease of ascorbic acid content up to 49%, and a general reduction of total phenolics was also noticed. In juices, total phenolics content increased after one year of storage. In both berries and juices total anthocyanins increased during storage by up to 85% and 50%, respectively. This study demonstrates that certain varieties, namely Redpoll, Jonkheer and London Market are good source of phytochemicals, retaining the nutritional value during processing and storage.
PB  - Springer, Dordrecht
T2  - Plant Foods for Human Nutrition
T1  - Biochemical Properties of Red Currant Varieties in Relation to Storage
EP  - 332
IS  - 4
SP  - 326
VL  - 65
DO  - 10.1007/s11130-010-0195-z
ER  - 

@article{
author = "Djordjević, Boban and Savikin, Katarina and Zdunić, Gordana and Janković, Teodora and Vulić, Todor and Oparnica, Čedo and Radivojević, Dragan",
year = "2010",
abstract = "Eleven red currant varieties (Ribes rubrum L.) cultured in Serbia were evaluated for some of their biochemical properties such as total phenolics, anthocyanins, ascorbic acid, invert sugar, soluble solid content, and acidity. The average amount of ascorbic acid varied from 50.5-71.6 mg/100 g FW, while concentration of invert sugars ranged from 6.0%-9.0%. The highest amounts of total phenolics and anthocyanins were detected in variety Redpoll (153.4 mg GAE/100 g FW and 19.3 mg/100 g, respectively). Red currants were processed to juice, and the phenolic and anthocyanin contents changed as a result of processing. Berries and juices were long-term stored at -18 A degrees C and changes in phytochemicals were monitored. In berries, storage caused the decrease of ascorbic acid content up to 49%, and a general reduction of total phenolics was also noticed. In juices, total phenolics content increased after one year of storage. In both berries and juices total anthocyanins increased during storage by up to 85% and 50%, respectively. This study demonstrates that certain varieties, namely Redpoll, Jonkheer and London Market are good source of phytochemicals, retaining the nutritional value during processing and storage.",
publisher = "Springer, Dordrecht",
journal = "Plant Foods for Human Nutrition",
title = "Biochemical Properties of Red Currant Varieties in Relation to Storage",
pages = "332-326",
number = "4",
volume = "65",
doi = "10.1007/s11130-010-0195-z"
}

Djordjević, B., Savikin, K., Zdunić, G., Janković, T., Vulić, T., Oparnica, Č.,& Radivojević, D.. (2010). Biochemical Properties of Red Currant Varieties in Relation to Storage. in Plant Foods for Human Nutrition
Springer, Dordrecht., 65(4), 326-332.
https://doi.org/10.1007/s11130-010-0195-z

Djordjević B, Savikin K, Zdunić G, Janković T, Vulić T, Oparnica Č, Radivojević D. Biochemical Properties of Red Currant Varieties in Relation to Storage. in Plant Foods for Human Nutrition. 2010;65(4):326-332.
doi:10.1007/s11130-010-0195-z .

Djordjević, Boban, Savikin, Katarina, Zdunić, Gordana, Janković, Teodora, Vulić, Todor, Oparnica, Čedo, Radivojević, Dragan, "Biochemical Properties of Red Currant Varieties in Relation to Storage" in Plant Foods for Human Nutrition, 65, no. 4 (2010):326-332,
https://doi.org/10.1007/s11130-010-0195-z . .

TY  - JOUR
AU  - Savikin, Katarina
AU  - Menković, Nebojša
AU  - Zdunić, Gordana
AU  - Tasić, Slavoljub R.
AU  - Ristić, Mihailo S.
AU  - Stević, Tatjana R.
AU  - Dajić-Stevanović, Zora
PY  - 2010
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/2371
AB  - Light yellowish, pleasant-smelling essential oils were obtained in 0.3%, 1.3%, and 0.8% yields from the aerial parts of S. cuneifolia Ten., M. thymifolia (Scop.) Fritsch., and M. dalmatica Benth, respectively. Thirty-four compounds were identified in the oil of M. dalmatica representing 98.7% of total oil composition, while in the oil of M. thymifolia, 21 were identified representing 78.2% of total oil composition. The major compounds in the oil of M. thymifolia included pulegone (50.4%), piperitenone (10.3%) and piperitenone oxide (4.3%), while the oil of M. dalmatica was rich in pulegone (26.7%), piperitenone (21.8%) and piperitenone oxide (25.4%). Fifty-five compounds were characterized in the oil of S. cuneifolia, representing 92.1% of total oil composition. Linalool (19.9%) and alpha-pinene (12.3%) were found to be the dominant compounds. Antimicrobial activity was noticed in all examined oils with MIC Values ranging from 5.6-54 mu g/mL. The most active was the oil of S. cuneifolia, which completely inhibited the growth of mostly all tested microorganisms at the lowest supplied concentration. Glandular trichomes (both peltate and capitate) and nonglandular, uniseriate, simple hairs were distributed on abaxial and adaxial surface of the leaves, calyces and stem in all examined species.
PB  - Taylor & Francis Inc, Philadelphia
T2  - Journal of Essential Oil Research
T1  - Chemical Composition and Antimicrobial Activity of the Essential Oils of Micromeria thymifolia (Scop.) Fritsch., M. dalmatica Benth., and Satureja cuneifolia Ten. and Its Secretory Elements
EP  - 96
IS  - 1
SP  - 91
VL  - 22
DO  - 10.1080/10412905.2010.9700271
ER  - 

@article{
author = "Savikin, Katarina and Menković, Nebojša and Zdunić, Gordana and Tasić, Slavoljub R. and Ristić, Mihailo S. and Stević, Tatjana R. and Dajić-Stevanović, Zora",
year = "2010",
abstract = "Light yellowish, pleasant-smelling essential oils were obtained in 0.3%, 1.3%, and 0.8% yields from the aerial parts of S. cuneifolia Ten., M. thymifolia (Scop.) Fritsch., and M. dalmatica Benth, respectively. Thirty-four compounds were identified in the oil of M. dalmatica representing 98.7% of total oil composition, while in the oil of M. thymifolia, 21 were identified representing 78.2% of total oil composition. The major compounds in the oil of M. thymifolia included pulegone (50.4%), piperitenone (10.3%) and piperitenone oxide (4.3%), while the oil of M. dalmatica was rich in pulegone (26.7%), piperitenone (21.8%) and piperitenone oxide (25.4%). Fifty-five compounds were characterized in the oil of S. cuneifolia, representing 92.1% of total oil composition. Linalool (19.9%) and alpha-pinene (12.3%) were found to be the dominant compounds. Antimicrobial activity was noticed in all examined oils with MIC Values ranging from 5.6-54 mu g/mL. The most active was the oil of S. cuneifolia, which completely inhibited the growth of mostly all tested microorganisms at the lowest supplied concentration. Glandular trichomes (both peltate and capitate) and nonglandular, uniseriate, simple hairs were distributed on abaxial and adaxial surface of the leaves, calyces and stem in all examined species.",
publisher = "Taylor & Francis Inc, Philadelphia",
journal = "Journal of Essential Oil Research",
title = "Chemical Composition and Antimicrobial Activity of the Essential Oils of Micromeria thymifolia (Scop.) Fritsch., M. dalmatica Benth., and Satureja cuneifolia Ten. and Its Secretory Elements",
pages = "96-91",
number = "1",
volume = "22",
doi = "10.1080/10412905.2010.9700271"
}

Savikin, K., Menković, N., Zdunić, G., Tasić, S. R., Ristić, M. S., Stević, T. R.,& Dajić-Stevanović, Z.. (2010). Chemical Composition and Antimicrobial Activity of the Essential Oils of Micromeria thymifolia (Scop.) Fritsch., M. dalmatica Benth., and Satureja cuneifolia Ten. and Its Secretory Elements. in Journal of Essential Oil Research
Taylor & Francis Inc, Philadelphia., 22(1), 91-96.
https://doi.org/10.1080/10412905.2010.9700271

Savikin K, Menković N, Zdunić G, Tasić SR, Ristić MS, Stević TR, Dajić-Stevanović Z. Chemical Composition and Antimicrobial Activity of the Essential Oils of Micromeria thymifolia (Scop.) Fritsch., M. dalmatica Benth., and Satureja cuneifolia Ten. and Its Secretory Elements. in Journal of Essential Oil Research. 2010;22(1):91-96.
doi:10.1080/10412905.2010.9700271 .

Savikin, Katarina, Menković, Nebojša, Zdunić, Gordana, Tasić, Slavoljub R., Ristić, Mihailo S., Stević, Tatjana R., Dajić-Stevanović, Zora, "Chemical Composition and Antimicrobial Activity of the Essential Oils of Micromeria thymifolia (Scop.) Fritsch., M. dalmatica Benth., and Satureja cuneifolia Ten. and Its Secretory Elements" in Journal of Essential Oil Research, 22, no. 1 (2010):91-96,
https://doi.org/10.1080/10412905.2010.9700271 . .