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Immobilization of Chaga extract in alginate beads for modified release: simplicity meets efficiency
dc.creator | Petrović, Predrag | |
dc.creator | Ivanović, Katarina | |
dc.creator | Octrue, Charly | |
dc.creator | Tumara, Mica | |
dc.creator | Jovanović, Aleksandra | |
dc.creator | Vunduk, Jovana | |
dc.creator | Nikšić, Miomir | |
dc.creator | Pjanović, Rada | |
dc.creator | Bugarski, Branko | |
dc.creator | Klaus, Anita | |
dc.date.accessioned | 2020-12-17T22:35:02Z | |
dc.date.available | 2020-12-17T22:35:02Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 0367-598X | |
dc.identifier.uri | http://aspace.agrif.bg.ac.rs/handle/123456789/5015 | |
dc.description.abstract | Chaga (Inonotus obliquus) is a parasitic fungus, which has been used in traditional medicine in Russia and other northern European countries in the treatment of cancer, gastrointestinal andliver diseases. It has been a subject of intensive researchrecently, confirming many of its health-beneficial effects. In order to obtain a product that would allow modified and prolonged release of the Chaga's active metabolites, hot water Chaga extract was immobilized using calcium - alginate. The extract, which was predominantly composed of carbohydrates (57 %), also contained a relatively high amount of antioxidants/phenolic compounds (130 mg gallic acid equivalents per g of dry extract) and exhibited pronounced radical scavenging activity. It showed significant antibacterial activity as well, inhibiting growth of tested bacterial strains at concentrations of 1.25-20 mg/mL. Entrapment efficiency was about 80 %, and the extract-alginate system showed pH-dependant extract release; there was negligible release at pH 1.75 (gastric pH), and the release gradually increased with the increase in pH, reaching similar to 43 % of immobilized extract at pH 8.5 after 90 min. Such a product could be used as a dietary supplement, adjuvant in therapy of gastrointestinal diseases or as a food additive. | en |
dc.publisher | Savez hemijskih inženjera, Beograd | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46010/RS// | |
dc.rights | openAccess | |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | HEMIJSKA INDUSTRIJA | |
dc.subject | mushrooms | en |
dc.subject | natural product | en |
dc.subject | antioxidant | en |
dc.subject | antimicrobial | en |
dc.subject | encapsulation | en |
dc.title | Immobilization of Chaga extract in alginate beads for modified release: simplicity meets efficiency | en |
dc.type | article | |
dc.rights.license | BY-NC-ND | |
dc.citation.epage | 335 | |
dc.citation.issue | 5 | |
dc.citation.other | 73(5): 325-335 | |
dc.citation.rank | M23 | |
dc.citation.spage | 325 | |
dc.citation.volume | 73 | |
dc.identifier.doi | 10.2298/HEMIND190819028P | |
dc.identifier.fulltext | http://aspace.agrif.bg.ac.rs/bitstream/id/3527/5012.pdf | |
dc.identifier.scopus | 2-s2.0-85075240386 | |
dc.identifier.wos | 000496945300005 | |
dc.type.version | publishedVersion |