Sladić, Dušan M.

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orcid::0000-0002-1000-9813
  • Sladić, Dušan M. (10)

Author's Bibliography

Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction

Filipović, Nenad; Bjelogrlić, Snežana; Marinković, Aleksandar; Verbić, Tatjana Z.; Cvijetić, Ilija N.; Sencanski, Milan; Rodić, Marko; Vujcić, Miroslava; Sladić, Dušan M.; Striković, Zlatko; Todorović, Tamara R.; Muller, Christian D.

(Royal Soc Chemistry, Cambridge, 2015)

TY  - JOUR
AU  - Filipović, Nenad
AU  - Bjelogrlić, Snežana
AU  - Marinković, Aleksandar
AU  - Verbić, Tatjana Z.
AU  - Cvijetić, Ilija N.
AU  - Sencanski, Milan
AU  - Rodić, Marko
AU  - Vujcić, Miroslava
AU  - Sladić, Dušan M.
AU  - Striković, Zlatko
AU  - Todorović, Tamara R.
AU  - Muller, Christian D.
PY  - 2015
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3749
AB  - A new Zn(II)-based potential chemotherapeutic agent was synthesized from the ligand 2-quinolinecarboxaldehyde selenosemicarbazone (Hqasesc). Single crystal X-ray diffraction analysis showed that the Zn(II) complex consists of a cation [Zn(Hqasesc)(2)](2+), two perchlorate anions and one ethanol solvent molecule. The interaction of calf thymus (CT) DNA and human serum albumin (HSA) with the Zn(II) complex was explored using absorption and emission spectral methods, and also has been supported by molecular docking studies. The complex has more affinity to minor DNA groove than major, with no significant intercalation. The HSA interaction studies of the complex revealed the quenching of the intrinsic fluorescence of the HSA through a static quenching mechanism. The antitumor activity of the ligand and the complex against pancreatic adenocarcinoma cell line (AsPC-1) and acute monocytic leukemia (THP-1) cells was evaluated. Both compounds are strong concentration-dependent apoptosis inducers in THP-1 cells. While Hqasesc in AsPC-1 cells induces apoptosis only at the highest concentration, treatment with the Zn complex shows a concentration-dependent apoptotic response, where the treated cells are arrested in the G1-to-S phase accompanied with extensive activation of caspase-8 and -9. These results indicate that the ligand and Zn(II) complex display cell phenotype specific activity.
PB  - Royal Soc Chemistry, Cambridge
T2  - RSC Advances
T1  - Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction
EP  - 95211
IS  - 115
SP  - 95191
VL  - 5
DO  - 10.1039/c5ra19849f
ER  - 
@article{
author = "Filipović, Nenad and Bjelogrlić, Snežana and Marinković, Aleksandar and Verbić, Tatjana Z. and Cvijetić, Ilija N. and Sencanski, Milan and Rodić, Marko and Vujcić, Miroslava and Sladić, Dušan M. and Striković, Zlatko and Todorović, Tamara R. and Muller, Christian D.",
year = "2015",
abstract = "A new Zn(II)-based potential chemotherapeutic agent was synthesized from the ligand 2-quinolinecarboxaldehyde selenosemicarbazone (Hqasesc). Single crystal X-ray diffraction analysis showed that the Zn(II) complex consists of a cation [Zn(Hqasesc)(2)](2+), two perchlorate anions and one ethanol solvent molecule. The interaction of calf thymus (CT) DNA and human serum albumin (HSA) with the Zn(II) complex was explored using absorption and emission spectral methods, and also has been supported by molecular docking studies. The complex has more affinity to minor DNA groove than major, with no significant intercalation. The HSA interaction studies of the complex revealed the quenching of the intrinsic fluorescence of the HSA through a static quenching mechanism. The antitumor activity of the ligand and the complex against pancreatic adenocarcinoma cell line (AsPC-1) and acute monocytic leukemia (THP-1) cells was evaluated. Both compounds are strong concentration-dependent apoptosis inducers in THP-1 cells. While Hqasesc in AsPC-1 cells induces apoptosis only at the highest concentration, treatment with the Zn complex shows a concentration-dependent apoptotic response, where the treated cells are arrested in the G1-to-S phase accompanied with extensive activation of caspase-8 and -9. These results indicate that the ligand and Zn(II) complex display cell phenotype specific activity.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "RSC Advances",
title = "Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction",
pages = "95211-95191",
number = "115",
volume = "5",
doi = "10.1039/c5ra19849f"
}
Filipović, N., Bjelogrlić, S., Marinković, A., Verbić, T. Z., Cvijetić, I. N., Sencanski, M., Rodić, M., Vujcić, M., Sladić, D. M., Striković, Z., Todorović, T. R.,& Muller, C. D.. (2015). Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction. in RSC Advances
Royal Soc Chemistry, Cambridge., 5(115), 95191-95211.
https://doi.org/10.1039/c5ra19849f
Filipović N, Bjelogrlić S, Marinković A, Verbić TZ, Cvijetić IN, Sencanski M, Rodić M, Vujcić M, Sladić DM, Striković Z, Todorović TR, Muller CD. Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction. in RSC Advances. 2015;5(115):95191-95211.
doi:10.1039/c5ra19849f .
Filipović, Nenad, Bjelogrlić, Snežana, Marinković, Aleksandar, Verbić, Tatjana Z., Cvijetić, Ilija N., Sencanski, Milan, Rodić, Marko, Vujcić, Miroslava, Sladić, Dušan M., Striković, Zlatko, Todorović, Tamara R., Muller, Christian D., "Zn(II) complex with 2-quinolinecarboxaldehyde selenosemicarbazone: synthesis, structure, interaction studies with DNA/HSA, molecular docking and caspase-8 and-9 independent apoptose induction" in RSC Advances, 5, no. 115 (2015):95191-95211,
https://doi.org/10.1039/c5ra19849f . .
32
27
33

A Comparative Study of DNA Binding and Cell Cycle Phase Perturbation by the Dinuclear Complex of Cd(II) with the Condensation Product of 2-Acetylpyridine and Malonic Acid Dihydrazide N ',N ' 2-bis[(1E)-1-(2-pyridyl) ethylidene] propanedihydrazide

Vujcić, Miroslava; Lazić, Milan; Milenković, Milica; Sladić, Dušan M.; Radulović, Siniša; Filipović, Nenad; Andjelković, Katarina

(Wiley-Blackwell, Malden, 2011)

TY  - JOUR
AU  - Vujcić, Miroslava
AU  - Lazić, Milan
AU  - Milenković, Milica
AU  - Sladić, Dušan M.
AU  - Radulović, Siniša
AU  - Filipović, Nenad
AU  - Andjelković, Katarina
PY  - 2011
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/2641
AB  - Organometallic Cd(II) compounds have recently attracted attention for their anticancer activity. The interaction of the dinuclear complex of Cd(II) with the condensation product of 2-acetylpyridine and malonic acid dihydrazide, N',N'(2)-bis[(1E)-1-(2pyridyl) ethylidene] propanedihydrazide (Cd(II)H(2)L), with calf thymus DNA (CT-DNA) was monitored by blue shift in UV-vis spectra of the complex. The binding constant of Cd(II) H2L complex with CT-DNA was determined (K(B) = 1.8 x 10(4) M(-1)) and was indicative of minor groove binding. Agarose gel electrophoretic changes in mobility of supercoiled and circular forms of pBR322 and pUC18 plasmids in the presence of the complex suggest that conformational changes in the plasmids occur upon binding of the Cd(II) H2L complex. The Cd(II) H2L complex induced perturbation of the cell cycle phase distribution and an increase in the percentage of cells in the sub-G1 phase of human cervical cancer HeLa cell line and murine melanoma B16 cell line. Immunoblotting analysis showed the overexpression of Bcl-2 protein with the Cd(II)H(2)L complex.
PB  - Wiley-Blackwell, Malden
T2  - Journal of Biochemical and Molecular Toxicology
T1  - A Comparative Study of DNA Binding and Cell Cycle Phase Perturbation by the Dinuclear Complex of Cd(II) with the Condensation Product of 2-Acetylpyridine and Malonic Acid Dihydrazide N ',N ' 2-bis[(1E)-1-(2-pyridyl) ethylidene] propanedihydrazide
EP  - 182
IS  - 3
SP  - 175
VL  - 25
DO  - 10.1002/jbt.20374
ER  - 
@article{
author = "Vujcić, Miroslava and Lazić, Milan and Milenković, Milica and Sladić, Dušan M. and Radulović, Siniša and Filipović, Nenad and Andjelković, Katarina",
year = "2011",
abstract = "Organometallic Cd(II) compounds have recently attracted attention for their anticancer activity. The interaction of the dinuclear complex of Cd(II) with the condensation product of 2-acetylpyridine and malonic acid dihydrazide, N',N'(2)-bis[(1E)-1-(2pyridyl) ethylidene] propanedihydrazide (Cd(II)H(2)L), with calf thymus DNA (CT-DNA) was monitored by blue shift in UV-vis spectra of the complex. The binding constant of Cd(II) H2L complex with CT-DNA was determined (K(B) = 1.8 x 10(4) M(-1)) and was indicative of minor groove binding. Agarose gel electrophoretic changes in mobility of supercoiled and circular forms of pBR322 and pUC18 plasmids in the presence of the complex suggest that conformational changes in the plasmids occur upon binding of the Cd(II) H2L complex. The Cd(II) H2L complex induced perturbation of the cell cycle phase distribution and an increase in the percentage of cells in the sub-G1 phase of human cervical cancer HeLa cell line and murine melanoma B16 cell line. Immunoblotting analysis showed the overexpression of Bcl-2 protein with the Cd(II)H(2)L complex.",
publisher = "Wiley-Blackwell, Malden",
journal = "Journal of Biochemical and Molecular Toxicology",
title = "A Comparative Study of DNA Binding and Cell Cycle Phase Perturbation by the Dinuclear Complex of Cd(II) with the Condensation Product of 2-Acetylpyridine and Malonic Acid Dihydrazide N ',N ' 2-bis[(1E)-1-(2-pyridyl) ethylidene] propanedihydrazide",
pages = "182-175",
number = "3",
volume = "25",
doi = "10.1002/jbt.20374"
}
Vujcić, M., Lazić, M., Milenković, M., Sladić, D. M., Radulović, S., Filipović, N.,& Andjelković, K.. (2011). A Comparative Study of DNA Binding and Cell Cycle Phase Perturbation by the Dinuclear Complex of Cd(II) with the Condensation Product of 2-Acetylpyridine and Malonic Acid Dihydrazide N ',N ' 2-bis[(1E)-1-(2-pyridyl) ethylidene] propanedihydrazide. in Journal of Biochemical and Molecular Toxicology
Wiley-Blackwell, Malden., 25(3), 175-182.
https://doi.org/10.1002/jbt.20374
Vujcić M, Lazić M, Milenković M, Sladić DM, Radulović S, Filipović N, Andjelković K. A Comparative Study of DNA Binding and Cell Cycle Phase Perturbation by the Dinuclear Complex of Cd(II) with the Condensation Product of 2-Acetylpyridine and Malonic Acid Dihydrazide N ',N ' 2-bis[(1E)-1-(2-pyridyl) ethylidene] propanedihydrazide. in Journal of Biochemical and Molecular Toxicology. 2011;25(3):175-182.
doi:10.1002/jbt.20374 .
Vujcić, Miroslava, Lazić, Milan, Milenković, Milica, Sladić, Dušan M., Radulović, Siniša, Filipović, Nenad, Andjelković, Katarina, "A Comparative Study of DNA Binding and Cell Cycle Phase Perturbation by the Dinuclear Complex of Cd(II) with the Condensation Product of 2-Acetylpyridine and Malonic Acid Dihydrazide N ',N ' 2-bis[(1E)-1-(2-pyridyl) ethylidene] propanedihydrazide" in Journal of Biochemical and Molecular Toxicology, 25, no. 3 (2011):175-182,
https://doi.org/10.1002/jbt.20374 . .
16
14
17

Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity

Filipović, Nenad; Borrmann, Horst; Todorović, Tamara; Borna, Marija; Spasojević, Vojislav; Sladić, Dušan M.; Novaković, Irena; Andjelković, Katarina

(Elsevier Science Sa, Lausanne, 2009)

TY  - JOUR
AU  - Filipović, Nenad
AU  - Borrmann, Horst
AU  - Todorović, Tamara
AU  - Borna, Marija
AU  - Spasojević, Vojislav
AU  - Sladić, Dušan M.
AU  - Novaković, Irena
AU  - Andjelković, Katarina
PY  - 2009
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/1998
AB  - Three novel copper(II) complexes as condensation derivatives of 2-pyridinecarboxaldehyde, 2-acetylpyridine or 2-quinolinecarboxaldehyde with ethyl hydrazinoacetate hydrochloride were synthesized. X-ray crystal structures of all three complexes were determined. Crystallographic data indicate a common basis of the structures with some major differences. Both pyridine derivatives form complexes of the type [CuCl2L] with distorted square-planar geometry around copper(II), but show a decisive difference in the side chain orientation. The quinoline derivative forms a dimeric complex of type [Cu2Cl4L2] with distorted trigonal bipyramidal geometry around copper(II), but a rather short Cu center dot center dot center dot Cu contact, which is reflected in its magnetic properties. All three complexes showed antibacterial activity.
PB  - Elsevier Science Sa, Lausanne
T2  - Inorganica Chimica Acta
T1  - Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity
EP  - 2000
IS  - 6
SP  - 1996
VL  - 362
DO  - 10.1016/j.ica.2008.09.019
ER  - 
@article{
author = "Filipović, Nenad and Borrmann, Horst and Todorović, Tamara and Borna, Marija and Spasojević, Vojislav and Sladić, Dušan M. and Novaković, Irena and Andjelković, Katarina",
year = "2009",
abstract = "Three novel copper(II) complexes as condensation derivatives of 2-pyridinecarboxaldehyde, 2-acetylpyridine or 2-quinolinecarboxaldehyde with ethyl hydrazinoacetate hydrochloride were synthesized. X-ray crystal structures of all three complexes were determined. Crystallographic data indicate a common basis of the structures with some major differences. Both pyridine derivatives form complexes of the type [CuCl2L] with distorted square-planar geometry around copper(II), but show a decisive difference in the side chain orientation. The quinoline derivative forms a dimeric complex of type [Cu2Cl4L2] with distorted trigonal bipyramidal geometry around copper(II), but a rather short Cu center dot center dot center dot Cu contact, which is reflected in its magnetic properties. All three complexes showed antibacterial activity.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Inorganica Chimica Acta",
title = "Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity",
pages = "2000-1996",
number = "6",
volume = "362",
doi = "10.1016/j.ica.2008.09.019"
}
Filipović, N., Borrmann, H., Todorović, T., Borna, M., Spasojević, V., Sladić, D. M., Novaković, I.,& Andjelković, K.. (2009). Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity. in Inorganica Chimica Acta
Elsevier Science Sa, Lausanne., 362(6), 1996-2000.
https://doi.org/10.1016/j.ica.2008.09.019
Filipović N, Borrmann H, Todorović T, Borna M, Spasojević V, Sladić DM, Novaković I, Andjelković K. Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity. in Inorganica Chimica Acta. 2009;362(6):1996-2000.
doi:10.1016/j.ica.2008.09.019 .
Filipović, Nenad, Borrmann, Horst, Todorović, Tamara, Borna, Marija, Spasojević, Vojislav, Sladić, Dušan M., Novaković, Irena, Andjelković, Katarina, "Copper(II) complexes of N-heteroaromatic hydrazones: Synthesis, X-ray structure, magnetic behavior, and antibacterial activity" in Inorganica Chimica Acta, 362, no. 6 (2009):1996-2000,
https://doi.org/10.1016/j.ica.2008.09.019 . .
45
38
44

Synthesis, characterization and biological activity evaluation of Pt(II), Pd(II), Co(III) and Ni(II) complexes with N-heteroaromatic selenosemicarbazones

Todorović, Tamara R.; Bacchi, Alessia; Sladić, Dušan M.; Todorović, Nina M.; Božić, Tatjana T.; Radanović, Dušanka; Filipović, Nenad; Pelizzi, Giancarlo; Andjelković, Katarina

(Elsevier Science Sa, Lausanne, 2009)

TY  - JOUR
AU  - Todorović, Tamara R.
AU  - Bacchi, Alessia
AU  - Sladić, Dušan M.
AU  - Todorović, Nina M.
AU  - Božić, Tatjana T.
AU  - Radanović, Dušanka
AU  - Filipović, Nenad
AU  - Pelizzi, Giancarlo
AU  - Andjelković, Katarina
PY  - 2009
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/2011
AB  - Five new complexes of Pt(II), Pd(II), Co(III) and Ni(II) with 2-pyridine(quinoline) carboxaldehyde selenose-micarbazones were synthesized and characterized. Crystal structures of Pt(II) complex with the pyridine derivative and Co(III) complex with the quinoline derivative were determined. In all complexes the ligands were coordinated through N2Se donor atom set forming either square-planar (Pt, Pd) or octahedral (Co, Ni) geometry. All complexes showed biological activity.
PB  - Elsevier Science Sa, Lausanne
T2  - Inorganica Chimica Acta
T1  - Synthesis, characterization and biological activity evaluation of Pt(II), Pd(II), Co(III) and Ni(II) complexes with N-heteroaromatic selenosemicarbazones
EP  - 3820
IS  - 10
SP  - 3813
VL  - 362
DO  - 10.1016/j.ica.2009.04.047
ER  - 
@article{
author = "Todorović, Tamara R. and Bacchi, Alessia and Sladić, Dušan M. and Todorović, Nina M. and Božić, Tatjana T. and Radanović, Dušanka and Filipović, Nenad and Pelizzi, Giancarlo and Andjelković, Katarina",
year = "2009",
abstract = "Five new complexes of Pt(II), Pd(II), Co(III) and Ni(II) with 2-pyridine(quinoline) carboxaldehyde selenose-micarbazones were synthesized and characterized. Crystal structures of Pt(II) complex with the pyridine derivative and Co(III) complex with the quinoline derivative were determined. In all complexes the ligands were coordinated through N2Se donor atom set forming either square-planar (Pt, Pd) or octahedral (Co, Ni) geometry. All complexes showed biological activity.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Inorganica Chimica Acta",
title = "Synthesis, characterization and biological activity evaluation of Pt(II), Pd(II), Co(III) and Ni(II) complexes with N-heteroaromatic selenosemicarbazones",
pages = "3820-3813",
number = "10",
volume = "362",
doi = "10.1016/j.ica.2009.04.047"
}
Todorović, T. R., Bacchi, A., Sladić, D. M., Todorović, N. M., Božić, T. T., Radanović, D., Filipović, N., Pelizzi, G.,& Andjelković, K.. (2009). Synthesis, characterization and biological activity evaluation of Pt(II), Pd(II), Co(III) and Ni(II) complexes with N-heteroaromatic selenosemicarbazones. in Inorganica Chimica Acta
Elsevier Science Sa, Lausanne., 362(10), 3813-3820.
https://doi.org/10.1016/j.ica.2009.04.047
Todorović TR, Bacchi A, Sladić DM, Todorović NM, Božić TT, Radanović D, Filipović N, Pelizzi G, Andjelković K. Synthesis, characterization and biological activity evaluation of Pt(II), Pd(II), Co(III) and Ni(II) complexes with N-heteroaromatic selenosemicarbazones. in Inorganica Chimica Acta. 2009;362(10):3813-3820.
doi:10.1016/j.ica.2009.04.047 .
Todorović, Tamara R., Bacchi, Alessia, Sladić, Dušan M., Todorović, Nina M., Božić, Tatjana T., Radanović, Dušanka, Filipović, Nenad, Pelizzi, Giancarlo, Andjelković, Katarina, "Synthesis, characterization and biological activity evaluation of Pt(II), Pd(II), Co(III) and Ni(II) complexes with N-heteroaromatic selenosemicarbazones" in Inorganica Chimica Acta, 362, no. 10 (2009):3813-3820,
https://doi.org/10.1016/j.ica.2009.04.047 . .
36
30
38

Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones

Gligorijević, Nevenka; Todorović, Tamara; Radulović, Siniša; Sladić, Dušan M.; Filipović, Nenad; Godjevac, Dejan; Jeremić, Dejan; Andjelković, Katarina

(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2009)

TY  - JOUR
AU  - Gligorijević, Nevenka
AU  - Todorović, Tamara
AU  - Radulović, Siniša
AU  - Sladić, Dušan M.
AU  - Filipović, Nenad
AU  - Godjevac, Dejan
AU  - Jeremić, Dejan
AU  - Andjelković, Katarina
PY  - 2009
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/2034
AB  - New complexes of Pt(II) and Pd(II) with 2-quinolinecarboxaldehyde selenosemicarbazone were synthesized and characterized by elemental analysis, NMR and IR spectroscopy and molar conductivity measurements. The assumed geometry of Pt(II) and Pd(II) complexes was square planar where the ligand was tridentately coordinated via the quinoline and imine nitrogen atoms and the selenium atom. The cytotoxic activity of the new Pt(II) and Pd(II) compounds, as well as of some previously synthesized Cd(II), Zn(II) and Ni(II) complexes with the same or analogous ligand, was tested against a panel of three human cancer cell lines: human cervix carcinoma cells (HeLa), human melanoma cells (FemX) and breast cancer cells (MDA-361). All investigated compounds, except Pt(II) complex, possess a strong dose-dependent cytotoxic activity of the same order of magnitude as cisplatin (CDDP). The investigation of potential of these compounds to induce HeLa cell cycle perturbations was also evaluated.
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux
T2  - European Journal of Medicinal Chemistry
T1  - Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones
EP  - 1629
IS  - 4
SP  - 1623
VL  - 44
DO  - 10.1016/j.ejmech.2008.07.033
ER  - 
@article{
author = "Gligorijević, Nevenka and Todorović, Tamara and Radulović, Siniša and Sladić, Dušan M. and Filipović, Nenad and Godjevac, Dejan and Jeremić, Dejan and Andjelković, Katarina",
year = "2009",
abstract = "New complexes of Pt(II) and Pd(II) with 2-quinolinecarboxaldehyde selenosemicarbazone were synthesized and characterized by elemental analysis, NMR and IR spectroscopy and molar conductivity measurements. The assumed geometry of Pt(II) and Pd(II) complexes was square planar where the ligand was tridentately coordinated via the quinoline and imine nitrogen atoms and the selenium atom. The cytotoxic activity of the new Pt(II) and Pd(II) compounds, as well as of some previously synthesized Cd(II), Zn(II) and Ni(II) complexes with the same or analogous ligand, was tested against a panel of three human cancer cell lines: human cervix carcinoma cells (HeLa), human melanoma cells (FemX) and breast cancer cells (MDA-361). All investigated compounds, except Pt(II) complex, possess a strong dose-dependent cytotoxic activity of the same order of magnitude as cisplatin (CDDP). The investigation of potential of these compounds to induce HeLa cell cycle perturbations was also evaluated.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux",
journal = "European Journal of Medicinal Chemistry",
title = "Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones",
pages = "1629-1623",
number = "4",
volume = "44",
doi = "10.1016/j.ejmech.2008.07.033"
}
Gligorijević, N., Todorović, T., Radulović, S., Sladić, D. M., Filipović, N., Godjevac, D., Jeremić, D.,& Andjelković, K.. (2009). Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux., 44(4), 1623-1629.
https://doi.org/10.1016/j.ejmech.2008.07.033
Gligorijević N, Todorović T, Radulović S, Sladić DM, Filipović N, Godjevac D, Jeremić D, Andjelković K. Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones. in European Journal of Medicinal Chemistry. 2009;44(4):1623-1629.
doi:10.1016/j.ejmech.2008.07.033 .
Gligorijević, Nevenka, Todorović, Tamara, Radulović, Siniša, Sladić, Dušan M., Filipović, Nenad, Godjevac, Dejan, Jeremić, Dejan, Andjelković, Katarina, "Synthesis and characterization of new Pt(II) and Pd(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone: Cytotoxic activity evaluation of Cd(II), Zn(II), Ni(II), Pt(II) and Pd(II) complexes with heteroaromatic selenosemicarbazones" in European Journal of Medicinal Chemistry, 44, no. 4 (2009):1623-1629,
https://doi.org/10.1016/j.ejmech.2008.07.033 . .
59
49
57

Synthesis, characterization and antimicrobial activity of Ni(II) and Zn(II) complexes with N ',N '(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide. Crystal structures of two highly solvated bimetallic complexes of Ni(II)

Todorović, Tamara R.; Rychlewska, Urszula; Warzajtis, Beata; Radanović, Dušanka; Filipović, Nenad; Pajić, Ivana A.; Sladić, Dušan M.; Andjelković, Katarina

(Pergamon-Elsevier Science Ltd, Oxford, 2009)

TY  - JOUR
AU  - Todorović, Tamara R.
AU  - Rychlewska, Urszula
AU  - Warzajtis, Beata
AU  - Radanović, Dušanka
AU  - Filipović, Nenad
AU  - Pajić, Ivana A.
AU  - Sladić, Dušan M.
AU  - Andjelković, Katarina
PY  - 2009
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/2105
AB  - The bimetallic [Ni-2(H(2)L2)(2)](ClO4)(4) (1), [Ni-2(HL2)(H(2)L2)](ClO4)(3) (2) and [Zn-2(H(2)L2)(2)](BF4)(4) (3) complexes (H(2)L2 = N',N'(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide) were synthesized and characterized. The structure of complexes (1) and (2) was established by X-ray analysis. NMR spectroscopy was used for the characterization of complex (3). The complexes (1) and (2) were obtained from the same synthetic reaction and two crystal types of these complexes have been isolated during the fractional crystallization process. In complex (1) each Ni(II) ion is coordinated with two NNO donor atom sets from two H(2)L2 ligands forming an octahedral geometry. Similarly, in complex (2) the octahedral geometry of each Ni(II) ion is attained by coordination of two NNO donor atom sets, one from the neutral and the other from the monoanionic form of the ligand. The antimicrobial activity of the ligand and complexes is also presented.
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Polyhedron
T1  - Synthesis, characterization and antimicrobial activity of Ni(II) and Zn(II) complexes with N ',N '(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide. Crystal structures of two highly solvated bimetallic complexes of Ni(II)
EP  - 2402
IS  - 12
SP  - 2397
VL  - 28
DO  - 10.1016/j.poly.2009.05.002
ER  - 
@article{
author = "Todorović, Tamara R. and Rychlewska, Urszula and Warzajtis, Beata and Radanović, Dušanka and Filipović, Nenad and Pajić, Ivana A. and Sladić, Dušan M. and Andjelković, Katarina",
year = "2009",
abstract = "The bimetallic [Ni-2(H(2)L2)(2)](ClO4)(4) (1), [Ni-2(HL2)(H(2)L2)](ClO4)(3) (2) and [Zn-2(H(2)L2)(2)](BF4)(4) (3) complexes (H(2)L2 = N',N'(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide) were synthesized and characterized. The structure of complexes (1) and (2) was established by X-ray analysis. NMR spectroscopy was used for the characterization of complex (3). The complexes (1) and (2) were obtained from the same synthetic reaction and two crystal types of these complexes have been isolated during the fractional crystallization process. In complex (1) each Ni(II) ion is coordinated with two NNO donor atom sets from two H(2)L2 ligands forming an octahedral geometry. Similarly, in complex (2) the octahedral geometry of each Ni(II) ion is attained by coordination of two NNO donor atom sets, one from the neutral and the other from the monoanionic form of the ligand. The antimicrobial activity of the ligand and complexes is also presented.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Polyhedron",
title = "Synthesis, characterization and antimicrobial activity of Ni(II) and Zn(II) complexes with N ',N '(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide. Crystal structures of two highly solvated bimetallic complexes of Ni(II)",
pages = "2402-2397",
number = "12",
volume = "28",
doi = "10.1016/j.poly.2009.05.002"
}
Todorović, T. R., Rychlewska, U., Warzajtis, B., Radanović, D., Filipović, N., Pajić, I. A., Sladić, D. M.,& Andjelković, K.. (2009). Synthesis, characterization and antimicrobial activity of Ni(II) and Zn(II) complexes with N ',N '(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide. Crystal structures of two highly solvated bimetallic complexes of Ni(II). in Polyhedron
Pergamon-Elsevier Science Ltd, Oxford., 28(12), 2397-2402.
https://doi.org/10.1016/j.poly.2009.05.002
Todorović TR, Rychlewska U, Warzajtis B, Radanović D, Filipović N, Pajić IA, Sladić DM, Andjelković K. Synthesis, characterization and antimicrobial activity of Ni(II) and Zn(II) complexes with N ',N '(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide. Crystal structures of two highly solvated bimetallic complexes of Ni(II). in Polyhedron. 2009;28(12):2397-2402.
doi:10.1016/j.poly.2009.05.002 .
Todorović, Tamara R., Rychlewska, Urszula, Warzajtis, Beata, Radanović, Dušanka, Filipović, Nenad, Pajić, Ivana A., Sladić, Dušan M., Andjelković, Katarina, "Synthesis, characterization and antimicrobial activity of Ni(II) and Zn(II) complexes with N ',N '(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide. Crystal structures of two highly solvated bimetallic complexes of Ni(II)" in Polyhedron, 28, no. 12 (2009):2397-2402,
https://doi.org/10.1016/j.poly.2009.05.002 . .
21
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Synthesis, structure and cytotoxic activity evaluation of a dinuclear complex of Cd(II) with N ',N '(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide

Filipović, Nenad; Bacchi, Alessia; Lazić, Milan; Pelizzi, Giancarlo; Radulović, Siniša; Sladić, Dušan M.; Todorović, Tamara R.; Andjelković, Katarina

(Elsevier, Amsterdam, 2008)

TY  - JOUR
AU  - Filipović, Nenad
AU  - Bacchi, Alessia
AU  - Lazić, Milan
AU  - Pelizzi, Giancarlo
AU  - Radulović, Siniša
AU  - Sladić, Dušan M.
AU  - Todorović, Tamara R.
AU  - Andjelković, Katarina
PY  - 2008
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/1832
AB  - A new dinuclear complex of Cd(II) with N',N'(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide (H2L) was synthesized and its crystal structure determined. The basic structural unit of the complex is the binuclear [Cd-2(H2O)(2)(H2L)(2)](4+) cation, where each cadmium atom is heptacoordinated by two tridentate H2L ligands, by means of the NNO chelating system, and one water molecule. A 12-membered macrocycle is defined at the core of the binuclear cation. The complex showed a pronounced cytotoxic activity to murine melanoma B16 cells and human cervical cancer HeLa cells.
PB  - Elsevier, Amsterdam
T2  - Inorganic Chemistry Communications
T1  - Synthesis, structure and cytotoxic activity evaluation of a dinuclear complex of Cd(II) with N ',N '(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide
EP  - 50
IS  - 1
SP  - 47
VL  - 11
DO  - 10.1016/j.inoche.2007.10.013
ER  - 
@article{
author = "Filipović, Nenad and Bacchi, Alessia and Lazić, Milan and Pelizzi, Giancarlo and Radulović, Siniša and Sladić, Dušan M. and Todorović, Tamara R. and Andjelković, Katarina",
year = "2008",
abstract = "A new dinuclear complex of Cd(II) with N',N'(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide (H2L) was synthesized and its crystal structure determined. The basic structural unit of the complex is the binuclear [Cd-2(H2O)(2)(H2L)(2)](4+) cation, where each cadmium atom is heptacoordinated by two tridentate H2L ligands, by means of the NNO chelating system, and one water molecule. A 12-membered macrocycle is defined at the core of the binuclear cation. The complex showed a pronounced cytotoxic activity to murine melanoma B16 cells and human cervical cancer HeLa cells.",
publisher = "Elsevier, Amsterdam",
journal = "Inorganic Chemistry Communications",
title = "Synthesis, structure and cytotoxic activity evaluation of a dinuclear complex of Cd(II) with N ',N '(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide",
pages = "50-47",
number = "1",
volume = "11",
doi = "10.1016/j.inoche.2007.10.013"
}
Filipović, N., Bacchi, A., Lazić, M., Pelizzi, G., Radulović, S., Sladić, D. M., Todorović, T. R.,& Andjelković, K.. (2008). Synthesis, structure and cytotoxic activity evaluation of a dinuclear complex of Cd(II) with N ',N '(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide. in Inorganic Chemistry Communications
Elsevier, Amsterdam., 11(1), 47-50.
https://doi.org/10.1016/j.inoche.2007.10.013
Filipović N, Bacchi A, Lazić M, Pelizzi G, Radulović S, Sladić DM, Todorović TR, Andjelković K. Synthesis, structure and cytotoxic activity evaluation of a dinuclear complex of Cd(II) with N ',N '(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide. in Inorganic Chemistry Communications. 2008;11(1):47-50.
doi:10.1016/j.inoche.2007.10.013 .
Filipović, Nenad, Bacchi, Alessia, Lazić, Milan, Pelizzi, Giancarlo, Radulović, Siniša, Sladić, Dušan M., Todorović, Tamara R., Andjelković, Katarina, "Synthesis, structure and cytotoxic activity evaluation of a dinuclear complex of Cd(II) with N ',N '(2)-bis[(1E)-1-(2-pyridyl)ethylidene]propanedihydrazide" in Inorganic Chemistry Communications, 11, no. 1 (2008):47-50,
https://doi.org/10.1016/j.inoche.2007.10.013 . .
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Synthesis, characterization and biological activity evaluation of novel Pd(II) and Pt(II) complexes with heterocyclic hydrazone ligands

Filipović, Nenad; Todorović, Tamara; Sladić, Dušan M.; Novaković, Irena; Jeremić, D.A.; Andjelković, K.K.

(8th Conference of the Yugoslav Materials Research Society, 2007)

TY  - CONF
AU  - Filipović, Nenad
AU  - Todorović, Tamara
AU  - Sladić, Dušan M.
AU  - Novaković, Irena
AU  - Jeremić, D.A.
AU  - Andjelković, K.K.
PY  - 2007
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/1361
AB  - New complexes of Pt(II) with condensation derivatives of ethyl hydrazino acetate and either 2-acetylpyridine or 2-quinolinecarboxaldehyde, and of Pd(II) with the condensation derivative of ethyl hydrazinoacetate and 2-quinolinecarboxaldehyde were synthesized and characterized by elemental analysis, IR, H-1- and C-13-NMR spectroscopy, and molar conductivity measurements. The complexes have a square planar geometry, ligands binding as bidentates in the neutral form, and the remaining two coordination sites being occupied by chloride ions. Biological activity of new complexes, and of previously synthesized Pd(II), Cd(II), Co(III) and Zn(II) complexes with this ligand type was evaluated by the brine shrimp test. All the complexes showed a moderate activity.
PB  - 8th Conference of the Yugoslav Materials Research Society
C3  - Materials Science Forum
T1  - Synthesis, characterization and biological activity evaluation of novel Pd(II) and Pt(II) complexes with heterocyclic hydrazone ligands
EP  - 427
SP  - 423
VL  - 555
DO  - 10.4028/0-87849-441-3.423
ER  - 
@conference{
author = "Filipović, Nenad and Todorović, Tamara and Sladić, Dušan M. and Novaković, Irena and Jeremić, D.A. and Andjelković, K.K.",
year = "2007",
abstract = "New complexes of Pt(II) with condensation derivatives of ethyl hydrazino acetate and either 2-acetylpyridine or 2-quinolinecarboxaldehyde, and of Pd(II) with the condensation derivative of ethyl hydrazinoacetate and 2-quinolinecarboxaldehyde were synthesized and characterized by elemental analysis, IR, H-1- and C-13-NMR spectroscopy, and molar conductivity measurements. The complexes have a square planar geometry, ligands binding as bidentates in the neutral form, and the remaining two coordination sites being occupied by chloride ions. Biological activity of new complexes, and of previously synthesized Pd(II), Cd(II), Co(III) and Zn(II) complexes with this ligand type was evaluated by the brine shrimp test. All the complexes showed a moderate activity.",
publisher = "8th Conference of the Yugoslav Materials Research Society",
journal = "Materials Science Forum",
title = "Synthesis, characterization and biological activity evaluation of novel Pd(II) and Pt(II) complexes with heterocyclic hydrazone ligands",
pages = "427-423",
volume = "555",
doi = "10.4028/0-87849-441-3.423"
}
Filipović, N., Todorović, T., Sladić, D. M., Novaković, I., Jeremić, D.A.,& Andjelković, K.K.. (2007). Synthesis, characterization and biological activity evaluation of novel Pd(II) and Pt(II) complexes with heterocyclic hydrazone ligands. in Materials Science Forum
8th Conference of the Yugoslav Materials Research Society., 555, 423-427.
https://doi.org/10.4028/0-87849-441-3.423
Filipović N, Todorović T, Sladić DM, Novaković I, Jeremić D, Andjelković K. Synthesis, characterization and biological activity evaluation of novel Pd(II) and Pt(II) complexes with heterocyclic hydrazone ligands. in Materials Science Forum. 2007;555:423-427.
doi:10.4028/0-87849-441-3.423 .
Filipović, Nenad, Todorović, Tamara, Sladić, Dušan M., Novaković, Irena, Jeremić, D.A., Andjelković, K.K., "Synthesis, characterization and biological activity evaluation of novel Pd(II) and Pt(II) complexes with heterocyclic hydrazone ligands" in Materials Science Forum, 555 (2007):423-427,
https://doi.org/10.4028/0-87849-441-3.423 . .
9
9

Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II)

Todorović, Tamara R.; Bacchi, Alessia; Juranić, Nenad O.; Sladić, Dušan M.; Pelizzi, Giancarlo; Božić, Tatjana T.; Filipović, Nenad; Andjelković, Katarina

(Pergamon-Elsevier Science Ltd, Oxford, 2007)

TY  - JOUR
AU  - Todorović, Tamara R.
AU  - Bacchi, Alessia
AU  - Juranić, Nenad O.
AU  - Sladić, Dušan M.
AU  - Pelizzi, Giancarlo
AU  - Božić, Tatjana T.
AU  - Filipović, Nenad
AU  - Andjelković, Katarina
PY  - 2007
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/1554
AB  - New complexes of Cd(II), Zn(II) and Ni(II) with 2-quinolinecarboxaldehyde selenosernicarbazone (Hqasesc) were synthesized and structurally characterized. The structure of the ligand, Cd(II) and Zn(II) complexes was determined by NMR and IR spectroscopy, elemental microanalysis and molar conductivity measurements. Both complexes occur in solution in two forms, the major tetrahedral and minor octahedral. In the major Cd(II) complex one qasesc(-) ligand is coordinated as a tridentate, the fourth coordination site being occupied by acetate, while in the major Zn(II) complex two qasesc- ligands are coordinated as bidentates. In both minor complexes two qasesc- ligands are coordinated as tridentates forming the octahedral geometry around the central metal ion. The only paramagnetic complex in the series is Ni(II) complex for which X-ray structure analysis was performed. The complex has the angularly distorted octahedral geometry with two qasesc- ligands coordinated as tridentates, in a similar way as in the minor complexes of Cd(11) and Zn(11).
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Polyhedron
T1  - Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II)
EP  - 3436
IS  - 13
SP  - 3428
VL  - 26
DO  - 10.1016/j.poly.2007.03.023
ER  - 
@article{
author = "Todorović, Tamara R. and Bacchi, Alessia and Juranić, Nenad O. and Sladić, Dušan M. and Pelizzi, Giancarlo and Božić, Tatjana T. and Filipović, Nenad and Andjelković, Katarina",
year = "2007",
abstract = "New complexes of Cd(II), Zn(II) and Ni(II) with 2-quinolinecarboxaldehyde selenosernicarbazone (Hqasesc) were synthesized and structurally characterized. The structure of the ligand, Cd(II) and Zn(II) complexes was determined by NMR and IR spectroscopy, elemental microanalysis and molar conductivity measurements. Both complexes occur in solution in two forms, the major tetrahedral and minor octahedral. In the major Cd(II) complex one qasesc(-) ligand is coordinated as a tridentate, the fourth coordination site being occupied by acetate, while in the major Zn(II) complex two qasesc- ligands are coordinated as bidentates. In both minor complexes two qasesc- ligands are coordinated as tridentates forming the octahedral geometry around the central metal ion. The only paramagnetic complex in the series is Ni(II) complex for which X-ray structure analysis was performed. The complex has the angularly distorted octahedral geometry with two qasesc- ligands coordinated as tridentates, in a similar way as in the minor complexes of Cd(11) and Zn(11).",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Polyhedron",
title = "Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II)",
pages = "3436-3428",
number = "13",
volume = "26",
doi = "10.1016/j.poly.2007.03.023"
}
Todorović, T. R., Bacchi, A., Juranić, N. O., Sladić, D. M., Pelizzi, G., Božić, T. T., Filipović, N.,& Andjelković, K.. (2007). Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II). in Polyhedron
Pergamon-Elsevier Science Ltd, Oxford., 26(13), 3428-3436.
https://doi.org/10.1016/j.poly.2007.03.023
Todorović TR, Bacchi A, Juranić NO, Sladić DM, Pelizzi G, Božić TT, Filipović N, Andjelković K. Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II). in Polyhedron. 2007;26(13):3428-3436.
doi:10.1016/j.poly.2007.03.023 .
Todorović, Tamara R., Bacchi, Alessia, Juranić, Nenad O., Sladić, Dušan M., Pelizzi, Giancarlo, Božić, Tatjana T., Filipović, Nenad, Andjelković, Katarina, "Synthesis and characterization of novel Cd(II), Zn(II) and Ni(II) complexes with 2-quinolinecarboxaldehyde selenosemicarbazone. Crystal structure of bis(2-quinolinecarboxaldehyde selenosemicarbazonato)nickel(II)" in Polyhedron, 26, no. 13 (2007):3428-3436,
https://doi.org/10.1016/j.poly.2007.03.023 . .
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Complexes of iron(II), iron(III) and zinc(II) with condensation derivatives of 2-acetylpyridine and oxalic or malonic dihydrazide. Crystal structure of tris[(1-(2-pyridyl)ethylidene)hydrazine]iron(II) perchlorate

Andjelković, K; Sladić, Dušan M.; Bacchi, Alessia; Pelizzi, Giancarlo; Filipović, Nenad; Rajković, M

(Springer, Dordrecht, 2005)

TY  - JOUR
AU  - Andjelković, K
AU  - Sladić, Dušan M.
AU  - Bacchi, Alessia
AU  - Pelizzi, Giancarlo
AU  - Filipović, Nenad
AU  - Rajković, M
PY  - 2005
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/1024
AB  - Complexes of zinc and iron with N', N'(2)- bis[(1E)-1-(2-pyridyl) ethylidene] ethanedihydrazide (H(2)L1) and N', N'(2)-bis[( 1E)-1-(2-pyridyl) ethylidene] propanedihydrazide (H(2)L2) were prepared. Zn-II complexes with both ligands have an octahedral geometry. In the complex of Zn-II with H(2)L1, the ligand is coordinated as a tridentate species in the monoanionic form, building two five-membered rings around Zn-II. Three remaining coordination sites are occupied by water molecules, and in the outer sphere there is a ClO4- ion. In the other Zn-II complex, the H(2)L2 ligand is coordinated in the enol form as a tetradenate species, forming a five-memebered, a six-membered and a seven-membered ring, the remaining coordination sites being occupied by water molecules, while in the outer sphere there are two ClO4- ions. The Fe-III complex with H(2)L2 is a high-spin octahedral complex. The ligand is coordinated in the enol form, in a tetradentate fashion via pyridine and hydrazone nitrogens. The remaining two coordination sites in the complex are occupied by water molecules and a Cl) ion, and in the outer sphere there are two Cl) anions. The octahedral Fe-III complex obtained from the reaction of FeCl(3)center dot 6H(2)O and H(2)L1 in absolute ethanol has the formula [Fe(HL1) Cl-2(H(2)0)] center dot 1.5H(2)O. However, during coordination of the H(2)L1 ligand to Fe-III in water, oxidative degradation of the side chain ( - CO - CO -) and reduction of Fe-III to Fe-II occurs, affording octahedral tris(1-(2-pyridyl) ethylidenehydrazine] iron(II) perchlorate, as confirmed by X-ray structure analysis.
PB  - Springer, Dordrecht
T2  - Transition Metal Chemistry
T1  - Complexes of iron(II), iron(III) and zinc(II) with condensation derivatives of 2-acetylpyridine and oxalic or malonic dihydrazide. Crystal structure of tris[(1-(2-pyridyl)ethylidene)hydrazine]iron(II) perchlorate
EP  - 250
IS  - 2
SP  - 243
VL  - 30
DO  - 10.1007/s11243-004-3173-1
ER  - 
@article{
author = "Andjelković, K and Sladić, Dušan M. and Bacchi, Alessia and Pelizzi, Giancarlo and Filipović, Nenad and Rajković, M",
year = "2005",
abstract = "Complexes of zinc and iron with N', N'(2)- bis[(1E)-1-(2-pyridyl) ethylidene] ethanedihydrazide (H(2)L1) and N', N'(2)-bis[( 1E)-1-(2-pyridyl) ethylidene] propanedihydrazide (H(2)L2) were prepared. Zn-II complexes with both ligands have an octahedral geometry. In the complex of Zn-II with H(2)L1, the ligand is coordinated as a tridentate species in the monoanionic form, building two five-membered rings around Zn-II. Three remaining coordination sites are occupied by water molecules, and in the outer sphere there is a ClO4- ion. In the other Zn-II complex, the H(2)L2 ligand is coordinated in the enol form as a tetradenate species, forming a five-memebered, a six-membered and a seven-membered ring, the remaining coordination sites being occupied by water molecules, while in the outer sphere there are two ClO4- ions. The Fe-III complex with H(2)L2 is a high-spin octahedral complex. The ligand is coordinated in the enol form, in a tetradentate fashion via pyridine and hydrazone nitrogens. The remaining two coordination sites in the complex are occupied by water molecules and a Cl) ion, and in the outer sphere there are two Cl) anions. The octahedral Fe-III complex obtained from the reaction of FeCl(3)center dot 6H(2)O and H(2)L1 in absolute ethanol has the formula [Fe(HL1) Cl-2(H(2)0)] center dot 1.5H(2)O. However, during coordination of the H(2)L1 ligand to Fe-III in water, oxidative degradation of the side chain ( - CO - CO -) and reduction of Fe-III to Fe-II occurs, affording octahedral tris(1-(2-pyridyl) ethylidenehydrazine] iron(II) perchlorate, as confirmed by X-ray structure analysis.",
publisher = "Springer, Dordrecht",
journal = "Transition Metal Chemistry",
title = "Complexes of iron(II), iron(III) and zinc(II) with condensation derivatives of 2-acetylpyridine and oxalic or malonic dihydrazide. Crystal structure of tris[(1-(2-pyridyl)ethylidene)hydrazine]iron(II) perchlorate",
pages = "250-243",
number = "2",
volume = "30",
doi = "10.1007/s11243-004-3173-1"
}
Andjelković, K., Sladić, D. M., Bacchi, A., Pelizzi, G., Filipović, N.,& Rajković, M.. (2005). Complexes of iron(II), iron(III) and zinc(II) with condensation derivatives of 2-acetylpyridine and oxalic or malonic dihydrazide. Crystal structure of tris[(1-(2-pyridyl)ethylidene)hydrazine]iron(II) perchlorate. in Transition Metal Chemistry
Springer, Dordrecht., 30(2), 243-250.
https://doi.org/10.1007/s11243-004-3173-1
Andjelković K, Sladić DM, Bacchi A, Pelizzi G, Filipović N, Rajković M. Complexes of iron(II), iron(III) and zinc(II) with condensation derivatives of 2-acetylpyridine and oxalic or malonic dihydrazide. Crystal structure of tris[(1-(2-pyridyl)ethylidene)hydrazine]iron(II) perchlorate. in Transition Metal Chemistry. 2005;30(2):243-250.
doi:10.1007/s11243-004-3173-1 .
Andjelković, K, Sladić, Dušan M., Bacchi, Alessia, Pelizzi, Giancarlo, Filipović, Nenad, Rajković, M, "Complexes of iron(II), iron(III) and zinc(II) with condensation derivatives of 2-acetylpyridine and oxalic or malonic dihydrazide. Crystal structure of tris[(1-(2-pyridyl)ethylidene)hydrazine]iron(II) perchlorate" in Transition Metal Chemistry, 30, no. 2 (2005):243-250,
https://doi.org/10.1007/s11243-004-3173-1 . .
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