TY  - JOUR
AU  - Zmejkovski, Bojana B.
AU  - Pantelić, Nebojša
AU  - Filipović, Lana
AU  - Arandelović, Sandra
AU  - Radulović, Siniša
AU  - Sabo, Tibor J.
AU  - Kaludjerović, Goran N.
PY  - 2017
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4473
AB  - Aims: Platinum(II) and platinum(IV) complexes [PtCln{(S,S)-(i-Am)(2)eddip}] (n = 2, 4: 1, 2, respectively; (S,S)-(i-Am)(2)eddip = O,O'-diisoamyl-(S,S)-ethylenediamine-N,N'-di-2-propanoate) were synthesized and characterized by elemental analysis, IR, H-1 and C-13 NMR spectroscopy and mass spectrometry. Method: Quantum chemical calculations were used to predict formed isomers of 1 and 2. Furthermore, reduction of 2 with ascorbic acid was followed by time-dependant C-13 NMR spectroscopy in order to enable assignation of the formed isomers for complex 1. In vitro cytotoxic activity was determined for 1 and 2 on a panel of five human tumor cell lines derived from cervix adenocarcinoma (HeLa), alveolar basal adenocarcinoma (A549), breast adenocarcinoma (MDA-453), colorectal cancer (LS 174), erythromyeloblastoid leukemia (K562), as well as one non-malignant human lung fibroblast cell line (MRC-5), using MTT assay. Result: Both complexes exhibited high (2 against K562: IC50 = 5.4 mu M), more active than cisplatin, to moderate activity (1). Both complexes caused considerable decrease of cell number in K562 cells in G1, S and G2 phases, concordantly increasing subpopulation in sub-G1 fraction. Morphological analysis of K562 cell death induced by platinum(II/IV) complexes indicate apoptosis.
PB  - Bentham Science Publ Ltd, Sharjah
T2  - Anti-Cancer Agents in Medicinal Chemistry
T1  - In Vitro Anticancer Evaluation of Platinum(II/IV) Complexes with Diisoamyl Ester of (S,S)-ethylenediamine-N,N'-di-2-propanoic Acid
EP  - 1143
IS  - 8
SP  - 1136
VL  - 17
DO  - 10.2174/1871520616666161207155634
ER  - 

@article{
author = "Zmejkovski, Bojana B. and Pantelić, Nebojša and Filipović, Lana and Arandelović, Sandra and Radulović, Siniša and Sabo, Tibor J. and Kaludjerović, Goran N.",
year = "2017",
abstract = "Aims: Platinum(II) and platinum(IV) complexes [PtCln{(S,S)-(i-Am)(2)eddip}] (n = 2, 4: 1, 2, respectively; (S,S)-(i-Am)(2)eddip = O,O'-diisoamyl-(S,S)-ethylenediamine-N,N'-di-2-propanoate) were synthesized and characterized by elemental analysis, IR, H-1 and C-13 NMR spectroscopy and mass spectrometry. Method: Quantum chemical calculations were used to predict formed isomers of 1 and 2. Furthermore, reduction of 2 with ascorbic acid was followed by time-dependant C-13 NMR spectroscopy in order to enable assignation of the formed isomers for complex 1. In vitro cytotoxic activity was determined for 1 and 2 on a panel of five human tumor cell lines derived from cervix adenocarcinoma (HeLa), alveolar basal adenocarcinoma (A549), breast adenocarcinoma (MDA-453), colorectal cancer (LS 174), erythromyeloblastoid leukemia (K562), as well as one non-malignant human lung fibroblast cell line (MRC-5), using MTT assay. Result: Both complexes exhibited high (2 against K562: IC50 = 5.4 mu M), more active than cisplatin, to moderate activity (1). Both complexes caused considerable decrease of cell number in K562 cells in G1, S and G2 phases, concordantly increasing subpopulation in sub-G1 fraction. Morphological analysis of K562 cell death induced by platinum(II/IV) complexes indicate apoptosis.",
publisher = "Bentham Science Publ Ltd, Sharjah",
journal = "Anti-Cancer Agents in Medicinal Chemistry",
title = "In Vitro Anticancer Evaluation of Platinum(II/IV) Complexes with Diisoamyl Ester of (S,S)-ethylenediamine-N,N'-di-2-propanoic Acid",
pages = "1143-1136",
number = "8",
volume = "17",
doi = "10.2174/1871520616666161207155634"
}

Zmejkovski, B. B., Pantelić, N., Filipović, L., Arandelović, S., Radulović, S., Sabo, T. J.,& Kaludjerović, G. N.. (2017). In Vitro Anticancer Evaluation of Platinum(II/IV) Complexes with Diisoamyl Ester of (S,S)-ethylenediamine-N,N'-di-2-propanoic Acid. in Anti-Cancer Agents in Medicinal Chemistry
Bentham Science Publ Ltd, Sharjah., 17(8), 1136-1143.
https://doi.org/10.2174/1871520616666161207155634

Zmejkovski BB, Pantelić N, Filipović L, Arandelović S, Radulović S, Sabo TJ, Kaludjerović GN. In Vitro Anticancer Evaluation of Platinum(II/IV) Complexes with Diisoamyl Ester of (S,S)-ethylenediamine-N,N'-di-2-propanoic Acid. in Anti-Cancer Agents in Medicinal Chemistry. 2017;17(8):1136-1143.
doi:10.2174/1871520616666161207155634 .

Zmejkovski, Bojana B., Pantelić, Nebojša, Filipović, Lana, Arandelović, Sandra, Radulović, Siniša, Sabo, Tibor J., Kaludjerović, Goran N., "In Vitro Anticancer Evaluation of Platinum(II/IV) Complexes with Diisoamyl Ester of (S,S)-ethylenediamine-N,N'-di-2-propanoic Acid" in Anti-Cancer Agents in Medicinal Chemistry, 17, no. 8 (2017):1136-1143,
https://doi.org/10.2174/1871520616666161207155634 . .

TY  - JOUR
AU  - Pantelić, Nebojša
AU  - Stanojković, Tatjana P.
AU  - Zmejkovski, Bojana B.
AU  - Kaludjerović, Goran N.
AU  - Sabo, Tibor J.
PY  - 2017
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4606
AB  - Six gold(III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N'-diacetate, general formula [AuCl2{(S,S)-R2eddch}]PF6, [(S,S)-eddch = (S,S)-ethylenediamine- N,N'-di-2-(3-cyclohexyl)propanoate, R = Me, Et, n-Pr, n-Bu, i-Bu, i-Am, 1-6, respectively], were tested against cancer cell lines such as human melanoma Fem-x, human colon carcinoma LS174T and non-small cell lung carcinoma A549 as well as a non-cancerous human embryonic lung fi broblasts MRC-5 using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) assay with the aim of assessing in vitro antitumoral activity and selectivity. All investigated complexes showed lower cytotoxicity and better or similar selectivity in comparison to cisplatin, used as reference compound. Complex [AuCl2{(S,S)-(i-Am)2eddch}]PF6 (6) demonstrated the highest activity against Fem-x (IC50 = 14.98 ± 0.34 μM). Additionally, the same complex expressed 4.5 times higher selectivity than cisplatin.
AB  - Šest kompleksa zlata(III) sa cikloheksil-funkcionalizovanim estrima etilendiamin-N,N'-diacetata, opšte formule [AuCl2{(S,S)-R2eddch}]PF6, ((S,S)-eddch = (S,S)-etilendiamin- N,N'-di-2-(3-cicloheksil)propanoat, R = Me, Et, n-Pr, n-Bu, i-Bu, i-Am, 1-6), ispitivano je na humanim ćelijskim linijama malignog melanoma Fem-x, karcinoma debelog creva LS174T, karcinoma pluća A549 kao i normalnim ćelijama MRC-5 (fetalni plućni fi broblast) korišćenjem 3-(4,5-dimetiltiazol- 2-yl)-2,5-difeniltetrazolium bromid (MTT) testa u cilju procene in vitro antitumorske aktivnosti i selektivnosti. Svi ispitivani kompleksi pokazali su manju citotoksičnost i bolju ili sličnu selektivnost u odnosu na cisplatinu koja je korišćena kao referentna supstanca. Kompleks 6 je pokazao najveću aktivnost sa IC50 (Fem-x) vrednošću od 14,98 ± 0,34 μM. Takođe, isti kompleks pokazuje 4,5 puta veću selektivnost od cisplatine.
PB  - Univerzitet u Kragujevcu - Fakultet medicinskih nauka, Kragujevac
T2  - Serbian Journal of Experimental and Clinical Research
T1  - Antiproliferative activity of gold (III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N'-diacetate
T1  - Antiproliferativna aktivnost zlato (III) kompleksa sa cikloheksil-funkcionalizovanim estrima etilendiamin-N,N'-diacetata
EP  - 294
IS  - 4
SP  - 289
VL  - 18
DO  - 10.1515/SJECR-2017-0067
ER  - 

@article{
author = "Pantelić, Nebojša and Stanojković, Tatjana P. and Zmejkovski, Bojana B. and Kaludjerović, Goran N. and Sabo, Tibor J.",
year = "2017",
abstract = "Six gold(III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N'-diacetate, general formula [AuCl2{(S,S)-R2eddch}]PF6, [(S,S)-eddch = (S,S)-ethylenediamine- N,N'-di-2-(3-cyclohexyl)propanoate, R = Me, Et, n-Pr, n-Bu, i-Bu, i-Am, 1-6, respectively], were tested against cancer cell lines such as human melanoma Fem-x, human colon carcinoma LS174T and non-small cell lung carcinoma A549 as well as a non-cancerous human embryonic lung fi broblasts MRC-5 using 3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide (MTT) assay with the aim of assessing in vitro antitumoral activity and selectivity. All investigated complexes showed lower cytotoxicity and better or similar selectivity in comparison to cisplatin, used as reference compound. Complex [AuCl2{(S,S)-(i-Am)2eddch}]PF6 (6) demonstrated the highest activity against Fem-x (IC50 = 14.98 ± 0.34 μM). Additionally, the same complex expressed 4.5 times higher selectivity than cisplatin., Šest kompleksa zlata(III) sa cikloheksil-funkcionalizovanim estrima etilendiamin-N,N'-diacetata, opšte formule [AuCl2{(S,S)-R2eddch}]PF6, ((S,S)-eddch = (S,S)-etilendiamin- N,N'-di-2-(3-cicloheksil)propanoat, R = Me, Et, n-Pr, n-Bu, i-Bu, i-Am, 1-6), ispitivano je na humanim ćelijskim linijama malignog melanoma Fem-x, karcinoma debelog creva LS174T, karcinoma pluća A549 kao i normalnim ćelijama MRC-5 (fetalni plućni fi broblast) korišćenjem 3-(4,5-dimetiltiazol- 2-yl)-2,5-difeniltetrazolium bromid (MTT) testa u cilju procene in vitro antitumorske aktivnosti i selektivnosti. Svi ispitivani kompleksi pokazali su manju citotoksičnost i bolju ili sličnu selektivnost u odnosu na cisplatinu koja je korišćena kao referentna supstanca. Kompleks 6 je pokazao najveću aktivnost sa IC50 (Fem-x) vrednošću od 14,98 ± 0,34 μM. Takođe, isti kompleks pokazuje 4,5 puta veću selektivnost od cisplatine.",
publisher = "Univerzitet u Kragujevcu - Fakultet medicinskih nauka, Kragujevac",
journal = "Serbian Journal of Experimental and Clinical Research",
title = "Antiproliferative activity of gold (III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N'-diacetate, Antiproliferativna aktivnost zlato (III) kompleksa sa cikloheksil-funkcionalizovanim estrima etilendiamin-N,N'-diacetata",
pages = "294-289",
number = "4",
volume = "18",
doi = "10.1515/SJECR-2017-0067"
}

Pantelić, N., Stanojković, T. P., Zmejkovski, B. B., Kaludjerović, G. N.,& Sabo, T. J.. (2017). Antiproliferative activity of gold (III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N'-diacetate. in Serbian Journal of Experimental and Clinical Research
Univerzitet u Kragujevcu - Fakultet medicinskih nauka, Kragujevac., 18(4), 289-294.
https://doi.org/10.1515/SJECR-2017-0067

Pantelić N, Stanojković TP, Zmejkovski BB, Kaludjerović GN, Sabo TJ. Antiproliferative activity of gold (III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N'-diacetate. in Serbian Journal of Experimental and Clinical Research. 2017;18(4):289-294.
doi:10.1515/SJECR-2017-0067 .

Pantelić, Nebojša, Stanojković, Tatjana P., Zmejkovski, Bojana B., Kaludjerović, Goran N., Sabo, Tibor J., "Antiproliferative activity of gold (III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N'-diacetate" in Serbian Journal of Experimental and Clinical Research, 18, no. 4 (2017):289-294,
https://doi.org/10.1515/SJECR-2017-0067 . .

TY  - JOUR
AU  - Pantelić, Nebojša
AU  - Zmejkovski, Bojana B.
AU  - Kolundzija, Branka
AU  - Dordić-Crnogorac, Marija
AU  - Vujić, Jelena M.
AU  - Dojčinović, Biljana
AU  - Trifunović, Srecko R.
AU  - Stanojković, Tatjana P.
AU  - Sabo, Tibor J.
AU  - Kaludjerović, Goran N.
PY  - 2017
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4340
AB  - Four novel gold(III) complexes of general formulae [AuCl2{(S,S)-R(2)eddl}]PF6 (R(2)eddl = O,O'-dialkyl-(S,S)-ethylenediamine-N,N'-di-2-(4-methyl)pentanoate, R= n-Pr, n-Bu, n-Pe, i-Bu; 1-4, respectively), were synthesized and characterized by elemental analysis, UV/Vis, IR, and NMR spectroscopy, as well as high resolution mass spectrometry. Density functional theory calculations pointed out that (R,R)-N,N'-configuration diastereoisomers were energetically the most favorable. Duo to high cytotoxic activity complex 3 was chosen for stability study in DMSO, no decomposition occurs within 24 h, and for the reaction with ascorbic acid in which was reduced immediately. Additionally, 3 interacts with bovine serum albumin (BSA) as proven by UV/Vis spectroscopy. In vitro antitumor activity was determined against human cervix adenocarcinoma (HeLa), human myelogenous leukemia (K562), and human melanoma (Fem-x) cancer cell lines, as well as against non-cancerous human embryonic lung fibroblast cells MRC-5. The highest activity was observed against K562 cells (IC50: 5.04-6.51 mu M). Selectivity indices showed that these complexes are less toxic than cisplatin. 3 had a similar viability kinetics on HeLa cells as cisplatin. Drug accumulation studies in HeLa cells showed that the total gold uptake increased much faster than that of cisplatin pointing out that 3 more efficiently enters the cells than cisplatin. Furthermore, morphological and cell cycle analysis reveal that gold(III) complexes induced apoptosis in time- and dose-dependent manner.
PB  - Elsevier Science Inc, New York
T2  - Journal of Inorganic Biochemistry
T1  - In vitro antitumor activity, metal uptake and reactivity with ascorbic acid and BSA of some gold(III) complexes with N,N '-ethylenediamine bidentate ester ligands
EP  - 66
SP  - 55
VL  - 172
DO  - 10.1016/j.jinorgbio.2017.04.001
ER  - 

@article{
author = "Pantelić, Nebojša and Zmejkovski, Bojana B. and Kolundzija, Branka and Dordić-Crnogorac, Marija and Vujić, Jelena M. and Dojčinović, Biljana and Trifunović, Srecko R. and Stanojković, Tatjana P. and Sabo, Tibor J. and Kaludjerović, Goran N.",
year = "2017",
abstract = "Four novel gold(III) complexes of general formulae [AuCl2{(S,S)-R(2)eddl}]PF6 (R(2)eddl = O,O'-dialkyl-(S,S)-ethylenediamine-N,N'-di-2-(4-methyl)pentanoate, R= n-Pr, n-Bu, n-Pe, i-Bu; 1-4, respectively), were synthesized and characterized by elemental analysis, UV/Vis, IR, and NMR spectroscopy, as well as high resolution mass spectrometry. Density functional theory calculations pointed out that (R,R)-N,N'-configuration diastereoisomers were energetically the most favorable. Duo to high cytotoxic activity complex 3 was chosen for stability study in DMSO, no decomposition occurs within 24 h, and for the reaction with ascorbic acid in which was reduced immediately. Additionally, 3 interacts with bovine serum albumin (BSA) as proven by UV/Vis spectroscopy. In vitro antitumor activity was determined against human cervix adenocarcinoma (HeLa), human myelogenous leukemia (K562), and human melanoma (Fem-x) cancer cell lines, as well as against non-cancerous human embryonic lung fibroblast cells MRC-5. The highest activity was observed against K562 cells (IC50: 5.04-6.51 mu M). Selectivity indices showed that these complexes are less toxic than cisplatin. 3 had a similar viability kinetics on HeLa cells as cisplatin. Drug accumulation studies in HeLa cells showed that the total gold uptake increased much faster than that of cisplatin pointing out that 3 more efficiently enters the cells than cisplatin. Furthermore, morphological and cell cycle analysis reveal that gold(III) complexes induced apoptosis in time- and dose-dependent manner.",
publisher = "Elsevier Science Inc, New York",
journal = "Journal of Inorganic Biochemistry",
title = "In vitro antitumor activity, metal uptake and reactivity with ascorbic acid and BSA of some gold(III) complexes with N,N '-ethylenediamine bidentate ester ligands",
pages = "66-55",
volume = "172",
doi = "10.1016/j.jinorgbio.2017.04.001"
}

Pantelić, N., Zmejkovski, B. B., Kolundzija, B., Dordić-Crnogorac, M., Vujić, J. M., Dojčinović, B., Trifunović, S. R., Stanojković, T. P., Sabo, T. J.,& Kaludjerović, G. N.. (2017). In vitro antitumor activity, metal uptake and reactivity with ascorbic acid and BSA of some gold(III) complexes with N,N '-ethylenediamine bidentate ester ligands. in Journal of Inorganic Biochemistry
Elsevier Science Inc, New York., 172, 55-66.
https://doi.org/10.1016/j.jinorgbio.2017.04.001

Pantelić N, Zmejkovski BB, Kolundzija B, Dordić-Crnogorac M, Vujić JM, Dojčinović B, Trifunović SR, Stanojković TP, Sabo TJ, Kaludjerović GN. In vitro antitumor activity, metal uptake and reactivity with ascorbic acid and BSA of some gold(III) complexes with N,N '-ethylenediamine bidentate ester ligands. in Journal of Inorganic Biochemistry. 2017;172:55-66.
doi:10.1016/j.jinorgbio.2017.04.001 .

Pantelić, Nebojša, Zmejkovski, Bojana B., Kolundzija, Branka, Dordić-Crnogorac, Marija, Vujić, Jelena M., Dojčinović, Biljana, Trifunović, Srecko R., Stanojković, Tatjana P., Sabo, Tibor J., Kaludjerović, Goran N., "In vitro antitumor activity, metal uptake and reactivity with ascorbic acid and BSA of some gold(III) complexes with N,N '-ethylenediamine bidentate ester ligands" in Journal of Inorganic Biochemistry, 172 (2017):55-66,
https://doi.org/10.1016/j.jinorgbio.2017.04.001 . .

TY  - JOUR
AU  - Pantelić, Nebojša
AU  - Stanković, Dalibor
AU  - Zmejkovski, Bojana B.
AU  - Kaludjerović, Goran N.
AU  - Sabo, Tibor J.
PY  - 2016
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4154
AB  - Oxidation-reduction properties of eleven gold(III) complexes with (S,S)-R(2)edda-type ligands was studied by cyclic and differential pulse voltammetry in DMSO. Series I: [AuCl2{(S,S)-R(2)eddip}]PF6, (S,S)-eddip = (S,S)-ethylenediamine-N,N'-di-2-propanoate, R = n-butyl, n-pentyl, isobutyl, isoamyl, cyclopentyl, 1-5; II: [AuCl2{(S,S)-R(2)eddch}]PF6, (S,S)-eddch = (S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate, R = methyl, ethyl, n-propyl, n-butyl, isobutyl, isoamyl, 6-11. Voltammograms in DMSO showed two successive irreversible reduction steps, where Au-I species were the final reduction product. Reduction potential values are in range from 116 to 156 mV (Ep(1)) and -520 to -572 mV (Ep(2)) for Series I and from 148 to 228 mV (Ep(1)) and -569 to -638 mV (Ep(2)) for Series II. In general, slightly easier reduction of complexes belonging to Series I (higher cytotoxicity) could be due to less steric hindrance around the gold center. Reduction potentials and anticancer activity are not in correlation.
PB  - Electrochemical Science Group, Beograd
T2  - International Journal of Electrochemical Science
T1  - Electrochemical properties of some gold(III) complexes with (S,S)-R(2)edda-type ligands
EP  - 1171
IS  - 2
SP  - 1162
VL  - 11
UR  - https://hdl.handle.net/21.15107/rcub_cherry_2060
ER  - 

@article{
author = "Pantelić, Nebojša and Stanković, Dalibor and Zmejkovski, Bojana B. and Kaludjerović, Goran N. and Sabo, Tibor J.",
year = "2016",
abstract = "Oxidation-reduction properties of eleven gold(III) complexes with (S,S)-R(2)edda-type ligands was studied by cyclic and differential pulse voltammetry in DMSO. Series I: [AuCl2{(S,S)-R(2)eddip}]PF6, (S,S)-eddip = (S,S)-ethylenediamine-N,N'-di-2-propanoate, R = n-butyl, n-pentyl, isobutyl, isoamyl, cyclopentyl, 1-5; II: [AuCl2{(S,S)-R(2)eddch}]PF6, (S,S)-eddch = (S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate, R = methyl, ethyl, n-propyl, n-butyl, isobutyl, isoamyl, 6-11. Voltammograms in DMSO showed two successive irreversible reduction steps, where Au-I species were the final reduction product. Reduction potential values are in range from 116 to 156 mV (Ep(1)) and -520 to -572 mV (Ep(2)) for Series I and from 148 to 228 mV (Ep(1)) and -569 to -638 mV (Ep(2)) for Series II. In general, slightly easier reduction of complexes belonging to Series I (higher cytotoxicity) could be due to less steric hindrance around the gold center. Reduction potentials and anticancer activity are not in correlation.",
publisher = "Electrochemical Science Group, Beograd",
journal = "International Journal of Electrochemical Science",
title = "Electrochemical properties of some gold(III) complexes with (S,S)-R(2)edda-type ligands",
pages = "1171-1162",
number = "2",
volume = "11",
url = "https://hdl.handle.net/21.15107/rcub_cherry_2060"
}

Pantelić, N., Stanković, D., Zmejkovski, B. B., Kaludjerović, G. N.,& Sabo, T. J.. (2016). Electrochemical properties of some gold(III) complexes with (S,S)-R(2)edda-type ligands. in International Journal of Electrochemical Science
Electrochemical Science Group, Beograd., 11(2), 1162-1171.
https://hdl.handle.net/21.15107/rcub_cherry_2060

Pantelić N, Stanković D, Zmejkovski BB, Kaludjerović GN, Sabo TJ. Electrochemical properties of some gold(III) complexes with (S,S)-R(2)edda-type ligands. in International Journal of Electrochemical Science. 2016;11(2):1162-1171.
https://hdl.handle.net/21.15107/rcub_cherry_2060 .

Pantelić, Nebojša, Stanković, Dalibor, Zmejkovski, Bojana B., Kaludjerović, Goran N., Sabo, Tibor J., "Electrochemical properties of some gold(III) complexes with (S,S)-R(2)edda-type ligands" in International Journal of Electrochemical Science, 11, no. 2 (2016):1162-1171,
https://hdl.handle.net/21.15107/rcub_cherry_2060 .

TY  - JOUR
AU  - Pantelić, Nebojša
AU  - Zmejkovski, Bojana B.
AU  - Marković, Dragana D.
AU  - Vujić, Jelena M.
AU  - Stanojković, Tatjana P.
AU  - Sabo, Tibor J.
AU  - Kaludjerović, Goran N.
PY  - 2016
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4095
AB  - A novel gold(III) complex, [AuCl2{(S,S)-Et(2)eddl}]PF6, ((S,S)-Et(2)eddl = O,O-diethyl ester of ethylenediamine-N,N-di-2-(4-methyl)pentanoic acid) was synthesized and characterized by IR, 1D (H-1 and C-13), and 2D (H,H-COSY and H,H-NOESY) NMR spectroscopy, mass spectrometry, and elemental analysis. Density functional theory calculations confirmed that (R,R)-N,N diastereoisomer was energetically the most stable isomer. In vitro antitumor action of ligand precursor [(S,S)-H(2)Et(2)eddl]Cl-2 and corresponding gold(III) complex was determined against tumor cell lines: human adenocarcinoma (HeLa), human colon carcinoma (LS174), human breast cancer (MCF7), non-small cell lung carcinoma cell line (A549), and non-cancerous cell line human embryonic lung fibroblast (MRC-5) using microculture tetrazolium test (MTT) assay. The results indicate that both ligand precursor and gold(III) complex have showed very good to moderate cytotoxic activity against all tested malignant cell lines. The highest activity was expressed by [AuCl2{(S,S)-Et(2)eddl}]PF6 against the LS174 cells, with IC50 value of 7.4 +/- 1.2 mu M.
PB  - MDPI, BASEL
T2  - Metals
T1  - Synthesis, Characterization, and Cytotoxicity of a Novel Gold(III) Complex with O,O-Diethyl Ester of Ethylenediamine-N,N-Di-2-(4-Methyl)Pentanoic Acid
IS  - 9
VL  - 6
DO  - 10.3390/met6090226
ER  - 

@article{
author = "Pantelić, Nebojša and Zmejkovski, Bojana B. and Marković, Dragana D. and Vujić, Jelena M. and Stanojković, Tatjana P. and Sabo, Tibor J. and Kaludjerović, Goran N.",
year = "2016",
abstract = "A novel gold(III) complex, [AuCl2{(S,S)-Et(2)eddl}]PF6, ((S,S)-Et(2)eddl = O,O-diethyl ester of ethylenediamine-N,N-di-2-(4-methyl)pentanoic acid) was synthesized and characterized by IR, 1D (H-1 and C-13), and 2D (H,H-COSY and H,H-NOESY) NMR spectroscopy, mass spectrometry, and elemental analysis. Density functional theory calculations confirmed that (R,R)-N,N diastereoisomer was energetically the most stable isomer. In vitro antitumor action of ligand precursor [(S,S)-H(2)Et(2)eddl]Cl-2 and corresponding gold(III) complex was determined against tumor cell lines: human adenocarcinoma (HeLa), human colon carcinoma (LS174), human breast cancer (MCF7), non-small cell lung carcinoma cell line (A549), and non-cancerous cell line human embryonic lung fibroblast (MRC-5) using microculture tetrazolium test (MTT) assay. The results indicate that both ligand precursor and gold(III) complex have showed very good to moderate cytotoxic activity against all tested malignant cell lines. The highest activity was expressed by [AuCl2{(S,S)-Et(2)eddl}]PF6 against the LS174 cells, with IC50 value of 7.4 +/- 1.2 mu M.",
publisher = "MDPI, BASEL",
journal = "Metals",
title = "Synthesis, Characterization, and Cytotoxicity of a Novel Gold(III) Complex with O,O-Diethyl Ester of Ethylenediamine-N,N-Di-2-(4-Methyl)Pentanoic Acid",
number = "9",
volume = "6",
doi = "10.3390/met6090226"
}

Pantelić, N., Zmejkovski, B. B., Marković, D. D., Vujić, J. M., Stanojković, T. P., Sabo, T. J.,& Kaludjerović, G. N.. (2016). Synthesis, Characterization, and Cytotoxicity of a Novel Gold(III) Complex with O,O-Diethyl Ester of Ethylenediamine-N,N-Di-2-(4-Methyl)Pentanoic Acid. in Metals
MDPI, BASEL., 6(9).
https://doi.org/10.3390/met6090226

Pantelić N, Zmejkovski BB, Marković DD, Vujić JM, Stanojković TP, Sabo TJ, Kaludjerović GN. Synthesis, Characterization, and Cytotoxicity of a Novel Gold(III) Complex with O,O-Diethyl Ester of Ethylenediamine-N,N-Di-2-(4-Methyl)Pentanoic Acid. in Metals. 2016;6(9).
doi:10.3390/met6090226 .

Pantelić, Nebojša, Zmejkovski, Bojana B., Marković, Dragana D., Vujić, Jelena M., Stanojković, Tatjana P., Sabo, Tibor J., Kaludjerović, Goran N., "Synthesis, Characterization, and Cytotoxicity of a Novel Gold(III) Complex with O,O-Diethyl Ester of Ethylenediamine-N,N-Di-2-(4-Methyl)Pentanoic Acid" in Metals, 6, no. 9 (2016),
https://doi.org/10.3390/met6090226 . .

TY  - JOUR
AU  - Pantelić, Nebojša
AU  - Stanojković, Tatjana P.
AU  - Zmejkovski, Bojana B.
AU  - Sabo, Tibor J.
AU  - Kaludjerović, Goran N.
PY  - 2015
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3779
AB  - Five novel gold(III) complexes of general formulas [AuCl2{(S,S)-R(2)eddip}]PF6, ((S,S)-eddip = (S,S)-ethylenediamine-N,N'-di-2-propanoate, R = n-Bu, n-Pe, i-Bu, i-Am, cPe; 1-5, respectively) were synthesized and characterized by UV/Vis, IR and NMR spectroscopy and mass spectrometry. DFT calculations indicated that (R,R)-N,N'-configuration diastereoisomers were the most stable for 1-5. 3 is stable in DMSO for at least 24 h, but immediate hydrolysis in PBS occurs. 3 is readily reduced with ascorbic acid and forms adducts with bovine serum albumin (BSA). In vitro anticancer activity of the gold(III) complexes against human cervix adenocarcinoma HeLa, human myelogenous leukemia K562, human melanoma Fem-x tumor cell lines, as well as against non-cancerous human embryonic lung fibroblast cell line MRC5 was determined using MIT assay. Complex 4 showed highest activity and selectivity (IC50(Femx) = 1.3 +/- 0.2; IC50(MRC-5)/IC50(Fem-x) = 72.5 +/- 12.4), 4 times more active and 28 times more selective than cisplatin. Complexes induced apoptotic mode of death in a time-dependent manner in HeLa cells.
PB  - Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux
T2  - European Journal of Medicinal Chemistry
T1  - In vitro anticancer activity of gold(III) complexes with some esters of (S,S)-ethylenediamine-N,N '-di-2-propanoic acid
EP  - 774
SP  - 766
VL  - 90
DO  - 10.1016/j.ejmech.2014.12.019
ER  - 

@article{
author = "Pantelić, Nebojša and Stanojković, Tatjana P. and Zmejkovski, Bojana B. and Sabo, Tibor J. and Kaludjerović, Goran N.",
year = "2015",
abstract = "Five novel gold(III) complexes of general formulas [AuCl2{(S,S)-R(2)eddip}]PF6, ((S,S)-eddip = (S,S)-ethylenediamine-N,N'-di-2-propanoate, R = n-Bu, n-Pe, i-Bu, i-Am, cPe; 1-5, respectively) were synthesized and characterized by UV/Vis, IR and NMR spectroscopy and mass spectrometry. DFT calculations indicated that (R,R)-N,N'-configuration diastereoisomers were the most stable for 1-5. 3 is stable in DMSO for at least 24 h, but immediate hydrolysis in PBS occurs. 3 is readily reduced with ascorbic acid and forms adducts with bovine serum albumin (BSA). In vitro anticancer activity of the gold(III) complexes against human cervix adenocarcinoma HeLa, human myelogenous leukemia K562, human melanoma Fem-x tumor cell lines, as well as against non-cancerous human embryonic lung fibroblast cell line MRC5 was determined using MIT assay. Complex 4 showed highest activity and selectivity (IC50(Femx) = 1.3 +/- 0.2; IC50(MRC-5)/IC50(Fem-x) = 72.5 +/- 12.4), 4 times more active and 28 times more selective than cisplatin. Complexes induced apoptotic mode of death in a time-dependent manner in HeLa cells.",
publisher = "Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux",
journal = "European Journal of Medicinal Chemistry",
title = "In vitro anticancer activity of gold(III) complexes with some esters of (S,S)-ethylenediamine-N,N '-di-2-propanoic acid",
pages = "774-766",
volume = "90",
doi = "10.1016/j.ejmech.2014.12.019"
}

Pantelić, N., Stanojković, T. P., Zmejkovski, B. B., Sabo, T. J.,& Kaludjerović, G. N.. (2015). In vitro anticancer activity of gold(III) complexes with some esters of (S,S)-ethylenediamine-N,N '-di-2-propanoic acid. in European Journal of Medicinal Chemistry
Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux., 90, 766-774.
https://doi.org/10.1016/j.ejmech.2014.12.019

Pantelić N, Stanojković TP, Zmejkovski BB, Sabo TJ, Kaludjerović GN. In vitro anticancer activity of gold(III) complexes with some esters of (S,S)-ethylenediamine-N,N '-di-2-propanoic acid. in European Journal of Medicinal Chemistry. 2015;90:766-774.
doi:10.1016/j.ejmech.2014.12.019 .

Pantelić, Nebojša, Stanojković, Tatjana P., Zmejkovski, Bojana B., Sabo, Tibor J., Kaludjerović, Goran N., "In vitro anticancer activity of gold(III) complexes with some esters of (S,S)-ethylenediamine-N,N '-di-2-propanoic acid" in European Journal of Medicinal Chemistry, 90 (2015):766-774,
https://doi.org/10.1016/j.ejmech.2014.12.019 . .

TY  - JOUR
AU  - Zmejkovski, Bojana B.
AU  - Savić, Aleksandar
AU  - Poljarević, Jelena
AU  - Pantelić, Nebojša
AU  - Arandelović, Sandra
AU  - Radulović, Siniša
AU  - Grgurić-Šipka, Sanja
AU  - Kaludjerović, Goran N.
AU  - Sabo, Tibor J.
PY  - 2014
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3400
AB  - Six palladium(II) complexes with (S,S)-R(2)edda-type esters ((S,S)-R2edda-type; (S,S)-eddch = (S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate, R = Me, Et, n-Pr, 1-3; (S,S)-pddch = (S,S)-propylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate, R = Et, n-Pr, 4, 5; and (S,S)-eddip = (S,S)-ethylenediamne-N,N'-di-2-propanoate, R = i-Am, 6) were synthesized, characterized by IR, NMR spectroscopy, ESI-MS and elemental analysis. DFT calculations indicate that in case of 1-4, the most stable isomers are with (S,S)- and (R,S)-configuration of nitrogen atoms, but for complex 6 (R,R)- and (R,S)-N,N'-configured isomers. Furthermore, complex 5 was obtained as (S,S)-N,N' configured isomer. Cytotoxicity study was performed against human cervical adenocarcinoma (HeLa), human alveolar basal adenocarcinoma (A549) and non-cancerous human fetal lung fibroblast (MRC-5) cell lines using colorimetric MTT assay. From the investigated palladium(II) complexes 2, 3 and 5 exhibited highest cytotoxic potential against HeLa (IC50: 28.5 +/- 3.9, 29.5 +/- 1.3 and 34.3 +/- 3.2, respectively).
PB  - Pergamon-Elsevier Science Ltd, Oxford
T2  - Polyhedron
T1  - Synthesis, characterization and in vitro antitumor activity of new palladium(II) complexes with (S,S)-R(2)edda-type esters
EP  - 111
SP  - 106
VL  - 80
DO  - 10.1016/j.poly.2014.02.026
ER  - 

@article{
author = "Zmejkovski, Bojana B. and Savić, Aleksandar and Poljarević, Jelena and Pantelić, Nebojša and Arandelović, Sandra and Radulović, Siniša and Grgurić-Šipka, Sanja and Kaludjerović, Goran N. and Sabo, Tibor J.",
year = "2014",
abstract = "Six palladium(II) complexes with (S,S)-R(2)edda-type esters ((S,S)-R2edda-type; (S,S)-eddch = (S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate, R = Me, Et, n-Pr, 1-3; (S,S)-pddch = (S,S)-propylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate, R = Et, n-Pr, 4, 5; and (S,S)-eddip = (S,S)-ethylenediamne-N,N'-di-2-propanoate, R = i-Am, 6) were synthesized, characterized by IR, NMR spectroscopy, ESI-MS and elemental analysis. DFT calculations indicate that in case of 1-4, the most stable isomers are with (S,S)- and (R,S)-configuration of nitrogen atoms, but for complex 6 (R,R)- and (R,S)-N,N'-configured isomers. Furthermore, complex 5 was obtained as (S,S)-N,N' configured isomer. Cytotoxicity study was performed against human cervical adenocarcinoma (HeLa), human alveolar basal adenocarcinoma (A549) and non-cancerous human fetal lung fibroblast (MRC-5) cell lines using colorimetric MTT assay. From the investigated palladium(II) complexes 2, 3 and 5 exhibited highest cytotoxic potential against HeLa (IC50: 28.5 +/- 3.9, 29.5 +/- 1.3 and 34.3 +/- 3.2, respectively).",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Polyhedron",
title = "Synthesis, characterization and in vitro antitumor activity of new palladium(II) complexes with (S,S)-R(2)edda-type esters",
pages = "111-106",
volume = "80",
doi = "10.1016/j.poly.2014.02.026"
}

Zmejkovski, B. B., Savić, A., Poljarević, J., Pantelić, N., Arandelović, S., Radulović, S., Grgurić-Šipka, S., Kaludjerović, G. N.,& Sabo, T. J.. (2014). Synthesis, characterization and in vitro antitumor activity of new palladium(II) complexes with (S,S)-R(2)edda-type esters. in Polyhedron
Pergamon-Elsevier Science Ltd, Oxford., 80, 106-111.
https://doi.org/10.1016/j.poly.2014.02.026

Zmejkovski BB, Savić A, Poljarević J, Pantelić N, Arandelović S, Radulović S, Grgurić-Šipka S, Kaludjerović GN, Sabo TJ. Synthesis, characterization and in vitro antitumor activity of new palladium(II) complexes with (S,S)-R(2)edda-type esters. in Polyhedron. 2014;80:106-111.
doi:10.1016/j.poly.2014.02.026 .

Zmejkovski, Bojana B., Savić, Aleksandar, Poljarević, Jelena, Pantelić, Nebojša, Arandelović, Sandra, Radulović, Siniša, Grgurić-Šipka, Sanja, Kaludjerović, Goran N., Sabo, Tibor J., "Synthesis, characterization and in vitro antitumor activity of new palladium(II) complexes with (S,S)-R(2)edda-type esters" in Polyhedron, 80 (2014):106-111,
https://doi.org/10.1016/j.poly.2014.02.026 . .

TY  - JOUR
AU  - Pantelić, Nebojša
AU  - Zmejkovski, Bojana B.
AU  - Stanojković, Tatjana P.
AU  - Jevtić, Verica V.
AU  - Radić, Gordana P.
AU  - Trifunović, Srecko R.
AU  - Kaludjerović, Goran N.
AU  - Sabo, Tibor J.
PY  - 2014
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3417
AB  - A novel (S,S)-R(2)eddip ester, O,O'-diisopentyl-(S,S)-ethylenediamine-N,N'-di-2-propanoate dihydrochloride (1) was synthesized and characterized by IR, H-1- and C-13-NMR spectroscopy, mass spectroscopy and elemental analysis. In vitro antitumor action of 1, and two more R(2)eddip esters, dialkyl (S,S)-ethylenediamine-N,N'-di-2-propanoate dihydrochlorides, obtained before (alkyl = n-Bu or n-Pe, 2 and 3, respectively), was determined against cervix adenocarcinoma (HeLa), human melanoma (Fem-x), human chronic myelogenous leukemia (K562) cells, and a non-cancerous cell line human embryonic lung fibroblast (MRC-5), using the microculture tetrazolium test MTT assay. Esters 1-3 showed higher cytotoxicity and better selectivity in comparison to cisplatin, used as reference compound. The highest activity was expressed by 1, with IC50(Fem-x) value of 1.51 +/- 0.09 mu M.
PB  - Srpsko hemijsko društvo, Beograd
T2  - JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
T1  - Synthesis and high in vitro cytotoxicity of some (S,S)-ethylenediamine-N,N '-di-2-propanoate dihydrochloride esters
EP  - 658
IS  - 6
SP  - 649
VL  - 79
DO  - 10.2298/JSC130512022P
ER  - 

@article{
author = "Pantelić, Nebojša and Zmejkovski, Bojana B. and Stanojković, Tatjana P. and Jevtić, Verica V. and Radić, Gordana P. and Trifunović, Srecko R. and Kaludjerović, Goran N. and Sabo, Tibor J.",
year = "2014",
abstract = "A novel (S,S)-R(2)eddip ester, O,O'-diisopentyl-(S,S)-ethylenediamine-N,N'-di-2-propanoate dihydrochloride (1) was synthesized and characterized by IR, H-1- and C-13-NMR spectroscopy, mass spectroscopy and elemental analysis. In vitro antitumor action of 1, and two more R(2)eddip esters, dialkyl (S,S)-ethylenediamine-N,N'-di-2-propanoate dihydrochlorides, obtained before (alkyl = n-Bu or n-Pe, 2 and 3, respectively), was determined against cervix adenocarcinoma (HeLa), human melanoma (Fem-x), human chronic myelogenous leukemia (K562) cells, and a non-cancerous cell line human embryonic lung fibroblast (MRC-5), using the microculture tetrazolium test MTT assay. Esters 1-3 showed higher cytotoxicity and better selectivity in comparison to cisplatin, used as reference compound. The highest activity was expressed by 1, with IC50(Fem-x) value of 1.51 +/- 0.09 mu M.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "JOURNAL OF THE SERBIAN CHEMICAL SOCIETY",
title = "Synthesis and high in vitro cytotoxicity of some (S,S)-ethylenediamine-N,N '-di-2-propanoate dihydrochloride esters",
pages = "658-649",
number = "6",
volume = "79",
doi = "10.2298/JSC130512022P"
}

Pantelić, N., Zmejkovski, B. B., Stanojković, T. P., Jevtić, V. V., Radić, G. P., Trifunović, S. R., Kaludjerović, G. N.,& Sabo, T. J.. (2014). Synthesis and high in vitro cytotoxicity of some (S,S)-ethylenediamine-N,N '-di-2-propanoate dihydrochloride esters. in JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
Srpsko hemijsko društvo, Beograd., 79(6), 649-658.
https://doi.org/10.2298/JSC130512022P

Pantelić N, Zmejkovski BB, Stanojković TP, Jevtić VV, Radić GP, Trifunović SR, Kaludjerović GN, Sabo TJ. Synthesis and high in vitro cytotoxicity of some (S,S)-ethylenediamine-N,N '-di-2-propanoate dihydrochloride esters. in JOURNAL OF THE SERBIAN CHEMICAL SOCIETY. 2014;79(6):649-658.
doi:10.2298/JSC130512022P .

Pantelić, Nebojša, Zmejkovski, Bojana B., Stanojković, Tatjana P., Jevtić, Verica V., Radić, Gordana P., Trifunović, Srecko R., Kaludjerović, Goran N., Sabo, Tibor J., "Synthesis and high in vitro cytotoxicity of some (S,S)-ethylenediamine-N,N '-di-2-propanoate dihydrochloride esters" in JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 79, no. 6 (2014):649-658,
https://doi.org/10.2298/JSC130512022P . .

TY  - JOUR
AU  - Pantelić, Nebojša
AU  - Zmejkovski, Bojana B.
AU  - Trifunović-Macedoljan, Jelena
AU  - Savić, Aleksandar
AU  - Stanković, Dalibor
AU  - Damjanović, Ana
AU  - Juranić, Zorica
AU  - Kaludjerović, Goran N.
AU  - Sabo, Tibor J.
PY  - 2013
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3140
AB  - Six novel gold(III) complexes containing O,O'-dialkyl-(S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate ([AuCl2{(S,S)-R(2)eddch}]PF6, R = Me, Et, n-Pr, n-Bu, i-Bu, i-Am; 1-6, respectively) were synthesized and characterized by elemental analysis, UV/Visible, IR and NMR spectroscopy, mass spectrometry and differential pulse voltammetry. Density functional theory (DFT) calculations confirmed that diastereoisomer with the N,N' atoms configured (S,S) was the most stable. In vitro antiproliferative activity was determined against human cervix adenocarcinoma HeLa and human myelogenous leukemia K562 tumor cell lines, as well as against rested and stimulated normal immunocompetent human peripheral blood mononuclear cells (PBMC) using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Complex 6 expressed the highest activity against K562 cells (IC50 = 3.8 +/- 0.5 mu M). Apoptosis, seen as condensation of HeLa cell nuclei was the mode of cell death induced by complexes 2-6. Complexes 3-6 induced death of K562 cells inhibiting cell entry in mitosis.
PB  - Elsevier Science Inc, New York
T2  - Journal of Inorganic Biochemistry
T1  - Gold(III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N '-diacetate
EP  - 153
SP  - 146
VL  - 128
DO  - 10.1016/j.jinorgbio.2013.08.002
ER  - 

@article{
author = "Pantelić, Nebojša and Zmejkovski, Bojana B. and Trifunović-Macedoljan, Jelena and Savić, Aleksandar and Stanković, Dalibor and Damjanović, Ana and Juranić, Zorica and Kaludjerović, Goran N. and Sabo, Tibor J.",
year = "2013",
abstract = "Six novel gold(III) complexes containing O,O'-dialkyl-(S,S)-ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate ([AuCl2{(S,S)-R(2)eddch}]PF6, R = Me, Et, n-Pr, n-Bu, i-Bu, i-Am; 1-6, respectively) were synthesized and characterized by elemental analysis, UV/Visible, IR and NMR spectroscopy, mass spectrometry and differential pulse voltammetry. Density functional theory (DFT) calculations confirmed that diastereoisomer with the N,N' atoms configured (S,S) was the most stable. In vitro antiproliferative activity was determined against human cervix adenocarcinoma HeLa and human myelogenous leukemia K562 tumor cell lines, as well as against rested and stimulated normal immunocompetent human peripheral blood mononuclear cells (PBMC) using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. Complex 6 expressed the highest activity against K562 cells (IC50 = 3.8 +/- 0.5 mu M). Apoptosis, seen as condensation of HeLa cell nuclei was the mode of cell death induced by complexes 2-6. Complexes 3-6 induced death of K562 cells inhibiting cell entry in mitosis.",
publisher = "Elsevier Science Inc, New York",
journal = "Journal of Inorganic Biochemistry",
title = "Gold(III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N '-diacetate",
pages = "153-146",
volume = "128",
doi = "10.1016/j.jinorgbio.2013.08.002"
}

Pantelić, N., Zmejkovski, B. B., Trifunović-Macedoljan, J., Savić, A., Stanković, D., Damjanović, A., Juranić, Z., Kaludjerović, G. N.,& Sabo, T. J.. (2013). Gold(III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N '-diacetate. in Journal of Inorganic Biochemistry
Elsevier Science Inc, New York., 128, 146-153.
https://doi.org/10.1016/j.jinorgbio.2013.08.002

Pantelić N, Zmejkovski BB, Trifunović-Macedoljan J, Savić A, Stanković D, Damjanović A, Juranić Z, Kaludjerović GN, Sabo TJ. Gold(III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N '-diacetate. in Journal of Inorganic Biochemistry. 2013;128:146-153.
doi:10.1016/j.jinorgbio.2013.08.002 .

Pantelić, Nebojša, Zmejkovski, Bojana B., Trifunović-Macedoljan, Jelena, Savić, Aleksandar, Stanković, Dalibor, Damjanović, Ana, Juranić, Zorica, Kaludjerović, Goran N., Sabo, Tibor J., "Gold(III) complexes with esters of cyclohexyl-functionalized ethylenediamine-N,N '-diacetate" in Journal of Inorganic Biochemistry, 128 (2013):146-153,
https://doi.org/10.1016/j.jinorgbio.2013.08.002 . .