Katanić Stanković, Jelena S.

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76345473-4f25-4539-8e5b-b3ce1ae7951b
  • Katanić Stanković, Jelena S. (5)
  • Katanić Stanković, Jelena (1)
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Author's Bibliography

Allium Species in the Balkan Region—Major Metabolites, Antioxidant and Antimicrobial Properties

Vuković, Sandra; Popović-Djordjević, Jelena B.; Kostić, Aleksandar Ž.; Pantelić, Nebojša D.; Srećković, Nikola; Akram, Muhammad; Laila, Umme; Katanić Stanković, Jelena S.

(2023)

TY  - JOUR
AU  - Vuković, Sandra
AU  - Popović-Djordjević, Jelena B.
AU  - Kostić, Aleksandar Ž.
AU  - Pantelić, Nebojša D.
AU  - Srećković, Nikola
AU  - Akram, Muhammad
AU  - Laila, Umme
AU  - Katanić Stanković, Jelena S.
PY  - 2023
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6317
AB  - Ever since ancient times, Allium species have played a significant role in the human diet, in traditional medicine for the treatment of many ailments, and in officinal medicine as a supplemental ingredient. The major metabolites of alliums, as well as their antioxidant and antimicrobial properties, with an emphasis on the species most represented in the Balkan region, are discussed in this review. Due to its richness in endemic species, the Balkan region is considered the genocenter of alliums. There are 56 recorded Allium species in the Balkans, and 17 of them are endemic. The most common and well-studied Allium species in the Balkans are A. cepa (onion), A. sativum (garlic), A. ampeloprasum (leek), A. schoenoprasum (chives), A. fistulosum (Welsh onion), and A. ursinum (wild garlic or bear’s garlic), which are known for their pungent taste and smell, especially noticeable in garlic and onion, and attributed to various organosulfur compounds. These plants are valued for their macronutrients and are used as desirable vegetables and spices. Additionally, phytochemicals such as organosulfur compounds, phenolics, fatty acids, and saponins are associated with the antioxidant and antimicrobial properties of these species, among many other bioactivities. All parts of the plant including the bulb, peel, clove, leaf, pseudostem, root, flower, and seed exhibit antioxidant properties in different in vitro assays. The characteristic phytocompounds that contribute to the antimicrobial activity of alliums include allicin, ajoene, allyl alcohol, and some diallyl sulfides. Nanoparticles synthesized using Allium species are also recognized for their notable antimicrobial properties. © 2023 by the authors.
T2  - Horticulturae
T2  - Horticulturae
T1  - Allium Species in the Balkan Region—Major Metabolites, Antioxidant and Antimicrobial Properties
IS  - 3
VL  - 9
DO  - 10.3390/horticulturae9030408
ER  - 
@article{
author = "Vuković, Sandra and Popović-Djordjević, Jelena B. and Kostić, Aleksandar Ž. and Pantelić, Nebojša D. and Srećković, Nikola and Akram, Muhammad and Laila, Umme and Katanić Stanković, Jelena S.",
year = "2023",
abstract = "Ever since ancient times, Allium species have played a significant role in the human diet, in traditional medicine for the treatment of many ailments, and in officinal medicine as a supplemental ingredient. The major metabolites of alliums, as well as their antioxidant and antimicrobial properties, with an emphasis on the species most represented in the Balkan region, are discussed in this review. Due to its richness in endemic species, the Balkan region is considered the genocenter of alliums. There are 56 recorded Allium species in the Balkans, and 17 of them are endemic. The most common and well-studied Allium species in the Balkans are A. cepa (onion), A. sativum (garlic), A. ampeloprasum (leek), A. schoenoprasum (chives), A. fistulosum (Welsh onion), and A. ursinum (wild garlic or bear’s garlic), which are known for their pungent taste and smell, especially noticeable in garlic and onion, and attributed to various organosulfur compounds. These plants are valued for their macronutrients and are used as desirable vegetables and spices. Additionally, phytochemicals such as organosulfur compounds, phenolics, fatty acids, and saponins are associated with the antioxidant and antimicrobial properties of these species, among many other bioactivities. All parts of the plant including the bulb, peel, clove, leaf, pseudostem, root, flower, and seed exhibit antioxidant properties in different in vitro assays. The characteristic phytocompounds that contribute to the antimicrobial activity of alliums include allicin, ajoene, allyl alcohol, and some diallyl sulfides. Nanoparticles synthesized using Allium species are also recognized for their notable antimicrobial properties. © 2023 by the authors.",
journal = "Horticulturae, Horticulturae",
title = "Allium Species in the Balkan Region—Major Metabolites, Antioxidant and Antimicrobial Properties",
number = "3",
volume = "9",
doi = "10.3390/horticulturae9030408"
}
Vuković, S., Popović-Djordjević, J. B., Kostić, A. Ž., Pantelić, N. D., Srećković, N., Akram, M., Laila, U.,& Katanić Stanković, J. S.. (2023). Allium Species in the Balkan Region—Major Metabolites, Antioxidant and Antimicrobial Properties. in Horticulturae, 9(3).
https://doi.org/10.3390/horticulturae9030408
Vuković S, Popović-Djordjević JB, Kostić AŽ, Pantelić ND, Srećković N, Akram M, Laila U, Katanić Stanković JS. Allium Species in the Balkan Region—Major Metabolites, Antioxidant and Antimicrobial Properties. in Horticulturae. 2023;9(3).
doi:10.3390/horticulturae9030408 .
Vuković, Sandra, Popović-Djordjević, Jelena B., Kostić, Aleksandar Ž., Pantelić, Nebojša D., Srećković, Nikola, Akram, Muhammad, Laila, Umme, Katanić Stanković, Jelena S., "Allium Species in the Balkan Region—Major Metabolites, Antioxidant and Antimicrobial Properties" in Horticulturae, 9, no. 3 (2023),
https://doi.org/10.3390/horticulturae9030408 . .
1
8

Natural Products: What can Nature Offer for the Promotion of Health?

Popović-Djordjević, Jelena B.; Katanić Stanković, Jelena S.

(2023)

TY  - JOUR
AU  - Popović-Djordjević, Jelena B.
AU  - Katanić Stanković, Jelena S.
PY  - 2023
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6373
T2  - Current Topics in Medicinal Chemistry
T2  - Current Topics in Medicinal Chemistry
T1  - Natural Products: What can Nature Offer for the Promotion of Health?
EP  - 628
IS  - 8
SP  - 627
VL  - 23
DO  - 10.2174/156802662308230522111136
ER  - 
@article{
author = "Popović-Djordjević, Jelena B. and Katanić Stanković, Jelena S.",
year = "2023",
journal = "Current Topics in Medicinal Chemistry, Current Topics in Medicinal Chemistry",
title = "Natural Products: What can Nature Offer for the Promotion of Health?",
pages = "628-627",
number = "8",
volume = "23",
doi = "10.2174/156802662308230522111136"
}
Popović-Djordjević, J. B.,& Katanić Stanković, J. S.. (2023). Natural Products: What can Nature Offer for the Promotion of Health?. in Current Topics in Medicinal Chemistry, 23(8), 627-628.
https://doi.org/10.2174/156802662308230522111136
Popović-Djordjević JB, Katanić Stanković JS. Natural Products: What can Nature Offer for the Promotion of Health?. in Current Topics in Medicinal Chemistry. 2023;23(8):627-628.
doi:10.2174/156802662308230522111136 .
Popović-Djordjević, Jelena B., Katanić Stanković, Jelena S., "Natural Products: What can Nature Offer for the Promotion of Health?" in Current Topics in Medicinal Chemistry, 23, no. 8 (2023):627-628,
https://doi.org/10.2174/156802662308230522111136 . .

Bioaccumulation potential of 'Meeker' and 'Willamette' raspberry (Rubus idaeus L.) fruits towards macro- and microelements and their nutritional evaluation

Jevremović, Stefan; Milivojević, Jasminka; Katanić Stanković, Jelena; Popović Đorđević, Jelena

(Kragujevac University, Institute for Information Technologies, 2023)

TY  - JOUR
AU  - Jevremović, Stefan
AU  - Milivojević, Jasminka
AU  - Katanić Stanković, Jelena
AU  - Popović Đorđević, Jelena
PY  - 2023
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6537
AB  - Raspberry (Rubus idaeus L.) is the most important type of berry fruit in the Republic of Serbia. The bioaccumulation factor (BF) for the elements detected in the fruits of the raspberry cultivars 'Willamette' and 'Meeker' was calculated to determine their bioaccumulation potential. In addition, the nutritional quality of fruits in relation to nutritionally essential elements was evaluated and compared with the recommended daily intake. For determining the concentrations of 19 macro- and microelements in fruits and the soil, the analytical technique of optical emission spectrometry with inductively coupled plasma was used. Among the analyzed elements, As, Cd, Co, Cr, Li and Mo were below the limit of detection in the fruits of both raspberry cultivars, whereas Na and Ni were detected only in fruits of the 'Meeker' cultivar. All analyzed elements were detected in the soil. The results of the work indicated the high potential of the studied cultivars to accumulate nutritional elements K and Ca. In both raspberry cultivars, there were no substantial differences in the bioaccumulation of most elements. However, two elements (B and Mn) can be singled out; the BF for B in the 'Willamette' fruit was 3 times lower compared to the BF in the 'Meeker' fruit, whereas, the BF value for Mn in the 'Willamette' fruit was almost 8 times higher compared to the BF value for the 'Meeker' fruit. Furthermore, the cultivars did not tend to accumulate potentially toxic elements such as Ba, Co, Cu and Ni. The nutritional evaluation revealed that the studied raspberry fruits are a good source of K, Ca, Mg, Fe, Mn and Cu. Based on the BF values, differences observed in the accumulation of B, Ba, Na, Ni and Mn may be attributed to the characteristics of the cultivars.
PB  - Kragujevac University, Institute for Information Technologies
T2  - Book of Proceedings of 2nd International Conference on Chemo and Bioinformatics
T1  - Bioaccumulation potential of 'Meeker' and 'Willamette' raspberry (Rubus idaeus L.) fruits towards macro- and microelements and their nutritional evaluation
EP  - 155
SP  - 152
DO  - 10.46793/ICCBI23.152J
ER  - 
@article{
author = "Jevremović, Stefan and Milivojević, Jasminka and Katanić Stanković, Jelena and Popović Đorđević, Jelena",
year = "2023",
abstract = "Raspberry (Rubus idaeus L.) is the most important type of berry fruit in the Republic of Serbia. The bioaccumulation factor (BF) for the elements detected in the fruits of the raspberry cultivars 'Willamette' and 'Meeker' was calculated to determine their bioaccumulation potential. In addition, the nutritional quality of fruits in relation to nutritionally essential elements was evaluated and compared with the recommended daily intake. For determining the concentrations of 19 macro- and microelements in fruits and the soil, the analytical technique of optical emission spectrometry with inductively coupled plasma was used. Among the analyzed elements, As, Cd, Co, Cr, Li and Mo were below the limit of detection in the fruits of both raspberry cultivars, whereas Na and Ni were detected only in fruits of the 'Meeker' cultivar. All analyzed elements were detected in the soil. The results of the work indicated the high potential of the studied cultivars to accumulate nutritional elements K and Ca. In both raspberry cultivars, there were no substantial differences in the bioaccumulation of most elements. However, two elements (B and Mn) can be singled out; the BF for B in the 'Willamette' fruit was 3 times lower compared to the BF in the 'Meeker' fruit, whereas, the BF value for Mn in the 'Willamette' fruit was almost 8 times higher compared to the BF value for the 'Meeker' fruit. Furthermore, the cultivars did not tend to accumulate potentially toxic elements such as Ba, Co, Cu and Ni. The nutritional evaluation revealed that the studied raspberry fruits are a good source of K, Ca, Mg, Fe, Mn and Cu. Based on the BF values, differences observed in the accumulation of B, Ba, Na, Ni and Mn may be attributed to the characteristics of the cultivars.",
publisher = "Kragujevac University, Institute for Information Technologies",
journal = "Book of Proceedings of 2nd International Conference on Chemo and Bioinformatics",
title = "Bioaccumulation potential of 'Meeker' and 'Willamette' raspberry (Rubus idaeus L.) fruits towards macro- and microelements and their nutritional evaluation",
pages = "155-152",
doi = "10.46793/ICCBI23.152J"
}
Jevremović, S., Milivojević, J., Katanić Stanković, J.,& Popović Đorđević, J.. (2023). Bioaccumulation potential of 'Meeker' and 'Willamette' raspberry (Rubus idaeus L.) fruits towards macro- and microelements and their nutritional evaluation. in Book of Proceedings of 2nd International Conference on Chemo and Bioinformatics
Kragujevac University, Institute for Information Technologies., 152-155.
https://doi.org/10.46793/ICCBI23.152J
Jevremović S, Milivojević J, Katanić Stanković J, Popović Đorđević J. Bioaccumulation potential of 'Meeker' and 'Willamette' raspberry (Rubus idaeus L.) fruits towards macro- and microelements and their nutritional evaluation. in Book of Proceedings of 2nd International Conference on Chemo and Bioinformatics. 2023;:152-155.
doi:10.46793/ICCBI23.152J .
Jevremović, Stefan, Milivojević, Jasminka, Katanić Stanković, Jelena, Popović Đorđević, Jelena, "Bioaccumulation potential of 'Meeker' and 'Willamette' raspberry (Rubus idaeus L.) fruits towards macro- and microelements and their nutritional evaluation" in Book of Proceedings of 2nd International Conference on Chemo and Bioinformatics (2023):152-155,
https://doi.org/10.46793/ICCBI23.152J . .

Polyphenolic Profile, Antioxidant and Antidiabetic Potential of Medlar (Mespilus germanica L.), Blackthorn (Prunus spinosa L.) and Common Hawthorn (Crataegus monogyna Jacq.) Fruit Extracts from Serbia

Katanić Stanković, Jelena S.; Mićanović, Nenad; Grozdanić, Nadja; Kostić, Aleksandar Ž; Gašić, Uroš; Stanojković, Tatjana; Popović-Djordjević, Jelena B.

(2022)

TY  - JOUR
AU  - Katanić Stanković, Jelena S.
AU  - Mićanović, Nenad
AU  - Grozdanić, Nadja
AU  - Kostić, Aleksandar Ž
AU  - Gašić, Uroš
AU  - Stanojković, Tatjana
AU  - Popović-Djordjević, Jelena B.
PY  - 2022
UR  - https://www.mdpi.com/2311-7524/8/11/1053
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6387
AB  - Plant-based food represents an excellent source of different nutrients and bioactive compounds, such as phenolics, carotenoids, vitamins, etc., with proven health benefits for humans. The content of selected phytochemicals, polyphenolic profile, and biological activity (antioxidant potential and α-glucosidase inhibitory activity) of fruit extracts of medlar (Mespilus germanica L.), blackthorn (Prunus spinosa L.), and common hawthorn (Crataegus monogyna Jacq.), the neglected Rosaceae species originated from Serbia were studied. Targeted UHPLC/(−)HESI–MS/MS quantitative analysis of phenolic compounds revealed pinocembrin only in medlar fruit extract, and it is the first report of this flavanone in medlar fruits. Total phenolic content did not differ between extracts, whereas significant differences were observed for the contents of total flavonoids, total phenolic acids, and total gallotannins. Monomeric anthocyanins and total anthocyanins were significantly higher in blackthorn compared to medlar and hawthorn fruit extracts (p < 0.05). DPPH· and ABTS·+ scavenging activities for examined fruits were modest compared to other natural antioxidants and BHT. The most potent inhibitory activity toward α-glucosidase expressed medlar and blackthorn extracts with IC50 values of 129.46 and 199.84 μg/mL, respectively, which was higher compared to the standard drug acarbose.
T2  - Horticulturae
T2  - Horticulturae
T1  - Polyphenolic Profile, Antioxidant and Antidiabetic Potential of Medlar (Mespilus germanica L.), Blackthorn (Prunus spinosa L.) and Common Hawthorn (Crataegus monogyna Jacq.) Fruit Extracts from Serbia
IS  - 11
SP  - 1053
VL  - 8
DO  - 10.3390/horticulturae8111053
ER  - 
@article{
author = "Katanić Stanković, Jelena S. and Mićanović, Nenad and Grozdanić, Nadja and Kostić, Aleksandar Ž and Gašić, Uroš and Stanojković, Tatjana and Popović-Djordjević, Jelena B.",
year = "2022",
abstract = "Plant-based food represents an excellent source of different nutrients and bioactive compounds, such as phenolics, carotenoids, vitamins, etc., with proven health benefits for humans. The content of selected phytochemicals, polyphenolic profile, and biological activity (antioxidant potential and α-glucosidase inhibitory activity) of fruit extracts of medlar (Mespilus germanica L.), blackthorn (Prunus spinosa L.), and common hawthorn (Crataegus monogyna Jacq.), the neglected Rosaceae species originated from Serbia were studied. Targeted UHPLC/(−)HESI–MS/MS quantitative analysis of phenolic compounds revealed pinocembrin only in medlar fruit extract, and it is the first report of this flavanone in medlar fruits. Total phenolic content did not differ between extracts, whereas significant differences were observed for the contents of total flavonoids, total phenolic acids, and total gallotannins. Monomeric anthocyanins and total anthocyanins were significantly higher in blackthorn compared to medlar and hawthorn fruit extracts (p < 0.05). DPPH· and ABTS·+ scavenging activities for examined fruits were modest compared to other natural antioxidants and BHT. The most potent inhibitory activity toward α-glucosidase expressed medlar and blackthorn extracts with IC50 values of 129.46 and 199.84 μg/mL, respectively, which was higher compared to the standard drug acarbose.",
journal = "Horticulturae, Horticulturae",
title = "Polyphenolic Profile, Antioxidant and Antidiabetic Potential of Medlar (Mespilus germanica L.), Blackthorn (Prunus spinosa L.) and Common Hawthorn (Crataegus monogyna Jacq.) Fruit Extracts from Serbia",
number = "11",
pages = "1053",
volume = "8",
doi = "10.3390/horticulturae8111053"
}
Katanić Stanković, J. S., Mićanović, N., Grozdanić, N., Kostić, A. Ž., Gašić, U., Stanojković, T.,& Popović-Djordjević, J. B.. (2022). Polyphenolic Profile, Antioxidant and Antidiabetic Potential of Medlar (Mespilus germanica L.), Blackthorn (Prunus spinosa L.) and Common Hawthorn (Crataegus monogyna Jacq.) Fruit Extracts from Serbia. in Horticulturae, 8(11), 1053.
https://doi.org/10.3390/horticulturae8111053
Katanić Stanković JS, Mićanović N, Grozdanić N, Kostić AŽ, Gašić U, Stanojković T, Popović-Djordjević JB. Polyphenolic Profile, Antioxidant and Antidiabetic Potential of Medlar (Mespilus germanica L.), Blackthorn (Prunus spinosa L.) and Common Hawthorn (Crataegus monogyna Jacq.) Fruit Extracts from Serbia. in Horticulturae. 2022;8(11):1053.
doi:10.3390/horticulturae8111053 .
Katanić Stanković, Jelena S., Mićanović, Nenad, Grozdanić, Nadja, Kostić, Aleksandar Ž, Gašić, Uroš, Stanojković, Tatjana, Popović-Djordjević, Jelena B., "Polyphenolic Profile, Antioxidant and Antidiabetic Potential of Medlar (Mespilus germanica L.), Blackthorn (Prunus spinosa L.) and Common Hawthorn (Crataegus monogyna Jacq.) Fruit Extracts from Serbia" in Horticulturae, 8, no. 11 (2022):1053,
https://doi.org/10.3390/horticulturae8111053 . .
1
12

Wild-Growing Species in the Service of Medicine: Environmental Challenges and Sustainable Production

Popović-Djordjević, Jelena B.; Fotirić Akšić, Milica; Katanić Stanković, Jelena S.; Pantelić, Nebojša Đ.; Mihailović, Vladimir; Aftab, Tariq

(Springer International Publishing, 2022)


                                            

                                            
Popović-Djordjević, J. B., Fotirić Akšić, M., Katanić Stanković, J. S., Pantelić, N. Đ., Mihailović, V.,& Aftab, T.. (2022). Wild-Growing Species in the Service of Medicine: Environmental Challenges and Sustainable Production. in Environmental Challenges and Medicinal Plants: Sustainable Production Solutions under Adverse Conditions
Springer International Publishing., 49-104.
https://hdl.handle.net/21.15107/rcub_agrospace_6409
Popović-Djordjević JB, Fotirić Akšić M, Katanić Stanković JS, Pantelić NĐ, Mihailović V, Aftab T. Wild-Growing Species in the Service of Medicine: Environmental Challenges and Sustainable Production. in Environmental Challenges and Medicinal Plants: Sustainable Production Solutions under Adverse Conditions. 2022;:49-104.
https://hdl.handle.net/21.15107/rcub_agrospace_6409 .
Popović-Djordjević, Jelena B., Fotirić Akšić, Milica, Katanić Stanković, Jelena S., Pantelić, Nebojša Đ., Mihailović, Vladimir, Aftab, Tariq, "Wild-Growing Species in the Service of Medicine: Environmental Challenges and Sustainable Production" in Environmental Challenges and Medicinal Plants: Sustainable Production Solutions under Adverse Conditions (2022):49-104,
https://hdl.handle.net/21.15107/rcub_agrospace_6409 .

Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs

Popović-Djordjević, Jelena; Quispe, Cristina; Giordo, Roberta; Kostić, Aleksandar; Katanić Stanković, Jelena S.; Tsouh Fokoue, Patrick Valere; Carbone, Katya; Martorell, Miquel; Kumar, Manoj; Pintus, Gianfranco; Sharifi-Rad, Javad; Docea, Anca Oana; Calina, Daniela

(Elsevier Masson s.r.l., 2022)

TY  - JOUR
AU  - Popović-Djordjević, Jelena
AU  - Quispe, Cristina
AU  - Giordo, Roberta
AU  - Kostić, Aleksandar
AU  - Katanić Stanković, Jelena S.
AU  - Tsouh Fokoue, Patrick Valere
AU  - Carbone, Katya
AU  - Martorell, Miquel
AU  - Kumar, Manoj
AU  - Pintus, Gianfranco
AU  - Sharifi-Rad, Javad
AU  - Docea, Anca Oana
AU  - Calina, Daniela
PY  - 2022
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6044
AB  - The human immunodeficiency virus (HIV) is responsible for acquired immune deficiency syndrome (AIDS), one of the major pandemic diseases. Highly active antiretroviral therapy (HAART) is the standard HIV-treatment regimen that usually comprises a combination of three or more antiretroviral drugs. HIV reverse transcriptase inhibitors are the main HAART target, which involves the use of both nucleoside reverse transcriptase inhibitors (NRTIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs). However, compounds affecting other aspects of HIV replication, such as virus entry and fusion or important viral enzymes, such as integrases and proteases, have also been developed. Natural compounds from different sources, like plants, microbial and marine organisms, showed promising anti-HIV activities to the point of establishing the basis for developing new drugs. Indeed, natural compounds-based therapies have the potential to become more efficient than conventional HAART, with less or no side effects. This review aims to gather and discuss the current information about the anti-HIV activity of natural and synthetic compounds, their history and mechanism of action as well as the role of plants and their bioactive compounds as a source of new anti-HIV drugs.
PB  - Elsevier Masson s.r.l.
T2  - European Journal of Medicinal Chemistry
T1  - Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs
SP  - 114217
VL  - 233
DO  - 10.1016/j.ejmech.2022.114217
ER  - 
@article{
author = "Popović-Djordjević, Jelena and Quispe, Cristina and Giordo, Roberta and Kostić, Aleksandar and Katanić Stanković, Jelena S. and Tsouh Fokoue, Patrick Valere and Carbone, Katya and Martorell, Miquel and Kumar, Manoj and Pintus, Gianfranco and Sharifi-Rad, Javad and Docea, Anca Oana and Calina, Daniela",
year = "2022",
abstract = "The human immunodeficiency virus (HIV) is responsible for acquired immune deficiency syndrome (AIDS), one of the major pandemic diseases. Highly active antiretroviral therapy (HAART) is the standard HIV-treatment regimen that usually comprises a combination of three or more antiretroviral drugs. HIV reverse transcriptase inhibitors are the main HAART target, which involves the use of both nucleoside reverse transcriptase inhibitors (NRTIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs). However, compounds affecting other aspects of HIV replication, such as virus entry and fusion or important viral enzymes, such as integrases and proteases, have also been developed. Natural compounds from different sources, like plants, microbial and marine organisms, showed promising anti-HIV activities to the point of establishing the basis for developing new drugs. Indeed, natural compounds-based therapies have the potential to become more efficient than conventional HAART, with less or no side effects. This review aims to gather and discuss the current information about the anti-HIV activity of natural and synthetic compounds, their history and mechanism of action as well as the role of plants and their bioactive compounds as a source of new anti-HIV drugs.",
publisher = "Elsevier Masson s.r.l.",
journal = "European Journal of Medicinal Chemistry",
title = "Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs",
pages = "114217",
volume = "233",
doi = "10.1016/j.ejmech.2022.114217"
}
Popović-Djordjević, J., Quispe, C., Giordo, R., Kostić, A., Katanić Stanković, J. S., Tsouh Fokoue, P. V., Carbone, K., Martorell, M., Kumar, M., Pintus, G., Sharifi-Rad, J., Docea, A. O.,& Calina, D.. (2022). Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs. in European Journal of Medicinal Chemistry
Elsevier Masson s.r.l.., 233, 114217.
https://doi.org/10.1016/j.ejmech.2022.114217
Popović-Djordjević J, Quispe C, Giordo R, Kostić A, Katanić Stanković JS, Tsouh Fokoue PV, Carbone K, Martorell M, Kumar M, Pintus G, Sharifi-Rad J, Docea AO, Calina D. Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs. in European Journal of Medicinal Chemistry. 2022;233:114217.
doi:10.1016/j.ejmech.2022.114217 .
Popović-Djordjević, Jelena, Quispe, Cristina, Giordo, Roberta, Kostić, Aleksandar, Katanić Stanković, Jelena S., Tsouh Fokoue, Patrick Valere, Carbone, Katya, Martorell, Miquel, Kumar, Manoj, Pintus, Gianfranco, Sharifi-Rad, Javad, Docea, Anca Oana, Calina, Daniela, "Natural products and synthetic analogues against HIV: A perspective to develop new potential anti-HIV drugs" in European Journal of Medicinal Chemistry, 233 (2022):114217,
https://doi.org/10.1016/j.ejmech.2022.114217 . .
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