Приказ основних података о документу

dc.creatorAraškov, Jovana B.
dc.creatorNikolić, Milan
dc.creatorArmaković, Stevan
dc.creatorArmaković, Sanja
dc.creatorRodić, Marko
dc.creatorVušnjevac, Aleksandar
dc.creatorPadrón, José M.
dc.creatorTodorović, Tamara R.
dc.creatorFilipović, Nenad R.
dc.date.accessioned2021-05-25T10:59:14Z
dc.date.available2021-05-25T10:59:14Z
dc.date.issued2021
dc.identifier.issn0022-2860
dc.identifier.urihttp://aspace.agrif.bg.ac.rs/handle/123456789/5849
dc.description.abstractTo evaluate the impact of chalcogen atom type, we performed a comparative study of antioxidant capacity and antiproliferative activity of a focused library of three pyridine-based hydrazonyl-1,3-selenazoles and their sulfur isosteres in five antioxidant assays and in six human solid tumor cell lines, respectively. In-silico calculations were further used to check pharmacokinetic profiles of investigated compounds such as drug-likeness parameters and interaction with water. Generally, selenium compounds appear to be more potent in comparison to sulfur isosteres in the performed essays.sr
dc.language.isoensr
dc.publisherElsevier B.V.sr
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200168/RS//sr
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200288/RS//sr
dc.rightsrestrictedAccesssr
dc.sourceJournal of Molecular Structuresr
dc.subjectAntioxidant activitysr
dc.subjectAntiproliferative activitysr
dc.subjectDFTsr
dc.subjectDrug likeness parameterssr
dc.subjectHydrazonyl‒thiazolessr
dc.subjectSingle crystal X-ray analysissr
dc.titleStructural, antioxidant, antiproliferative and in‒silico study of pyridine-based hydrazonyl‒selenazoles and their sulphur isosteressr
dc.typearticlesr
dc.rights.licenseARRsr
dc.citation.rankM22
dc.citation.spage130512
dc.citation.volume1240
dc.identifier.doi10.1016/j.molstruc.2021.130512
dc.identifier.scopus2-s2.0-85105531083
dc.identifier.wos000664244900012
dc.type.versionpublishedVersionsr


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