University of Belgrade - Faculty of Agriculture
AgroSpace - Faculty of Agriculture Repository
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   AgroSpace
  • Poljoprivredni fakultet
  • Radovi istraživača / Researchers’ publications
  • View Item
  •   AgroSpace
  • Poljoprivredni fakultet
  • Radovi istraživača / Researchers’ publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Fermentation characteristics of novel Coriolus versicolor and Lentinus edodes kombucha beverages and immunomodulatory potential of their polysaccharide extracts

Authorized Users Only
2021
Authors
Sknepnek, Aleksandra
Tomić, Sergej
Miletić, Dunja
Lević, Steva
Čolić, Miodrag
Nedović, Viktor
Nikšić, Miomir
Article (Published version)
Metadata
Show full item record
Abstract
Medicinal mushrooms, Coriolus versicolor and Lentinus edodes are extremely attractive as nutraceuticals. Here we used fruiting bodies to prepare novel kombucha beverage. Microbiological, physicochemical and chemical properties were monitored for eleven days, while the immunological properties of kombucha polysaccharide extracts were determined in peripheral blood mononuclear cell (PBMC) cultures. FTIR analysis of polysaccharide extracts showed dominant presence of polysaccharides, in addition to phenols, lipids and proteins. C. versicolor kombucha extract displayed more complex polysaccharides, and a higher content of total polysaccharides, phenols and flavonoids compared to L. edodes kombucha extract. The extracts were not cytotoxic for PBMC in vitro up to 500 µg/ml, while immunomodulatory effects depended on their chemical compositions. The most prominent effect was on the reduction of Th2 cytokines and IL-10 in PBMC cultures. Based on these results, novel kombucha products could be ...recommended as functional beverages or nutraceuticals with potentially beneficial immunomodulatory effects in allergies.

Keywords:
Cytokines / Immunomodulation / Kombucha / Medicinal mushrooms
Source:
Food Chemistry, 2021, 342, 128344-
Publisher:
  • Elsevier
Funding / projects:
  • Ministry of Education, Science and Technological Development, Republic of Serbia, Grant no. 200116 (University of Belgrade, Faculty of Agriculture) (RS-200116)
  • Application of functionalyzed carbon nanotubes and gold nanoparticles for preparation of dendritic cells for tumor therapy (RS-175102)
Note:
  • The peer-reviewed version: http://aspace.agrif.bg.ac.rs/handle/123456789/5771
  • Supplementary material: http://aspace.agrif.bg.ac.rs/handle/123456789/5996
Related info:
  • Referenced by
    http://aspace.agrif.bg.ac.rs/handle/123456789/5996

DOI: 10.1016/j.foodchem.2020.128344

ISSN: 0308-8146

WoS: 000617936400015

Scopus: 2-s2.0-85094559035
[ Google Scholar ]
URI
http://aspace.agrif.bg.ac.rs/handle/123456789/5771
Collections
  • Radovi istraživača / Researchers’ publications
Institution/Community
Poljoprivredni fakultet

DSpace software copyright © 2002-2015  DuraSpace
About the AgroSpace Repository | Send Feedback

re3dataOpenAIRERCUB
 

 

All of DSpaceCommunitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About the AgroSpace Repository | Send Feedback

re3dataOpenAIRERCUB