Investigation of Antioxidative Mechanisams of Kaempferol with Hydroxyl Radical and Superoxide Radical Anion

Jeremić, S; Djorović, J; Milenković, D; Marković, Zoran; Dimitrić-Marković, Jasmina

Ispitivanje antioksidativnih mehanizama kempferola sa hidroksi radikalom i superoksid radikal anjonom

2014

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Authors

Jeremić, S
Djorović, J
Milenković, D
Marković, Zoran
Dimitrić-Marković, Jasmina

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Abstract

Kaempferol, one of the most bioactive plant flavonoids was theoretically (at M05-2X/6-311G(d,p) level of theory) investigated for its ability scavange potentially highly damaging hydroxyl and superoxide anion radicals. Theoretical calculations point to HAT and SPLET mechanisms as operative for kaempferol in all solvents under investigations.

Teoretski (na M05-2X/6-311G(d,p) nivou teorije) je ispitivana sposobnost kempferola, važnog bioaktivnog biljnog jedinjenja flavonoida, da reaguje sa potencijalno veoma štetnim hidroksi radikalom i superoksid radikal anjonom. Proračuni su pokazali da su HAT i SPLET mogući mehanizmi u svim rastvaračima.

Keywords:

hyrdoxyl radical / superoxide anion radical / AT and SPLET mechanisms / kaempferol / hidroksi radikal / superoksid radikal anjon / HAT i SPLET mehanizmi

Source:
19. Savetovanje o biotehnologiji sa međunarodnim učešćem, Čačak, 07.- 08. 03. 2014., 2014