Exposure assessment and risk characterization of aflatoxins intake through consumption of maize products in the adult populations of Serbia, Croatia and Greece

Abstract

The main objective of this research was to perform an exposure assessment of aflatoxins intake through consumption of maize products in Serbia, Croatia, and Greece. Food consumption survey of maize-based products has been performed during 2017 in the three countries with at least 1,000 interviewees per country covering their dietary habits and body weight. Values for the concentration of aflatoxins were extracted from available research published in the last ten years. Finally, a Monte Carlo analysis of 100,000 iterations was performed to estimate the intake of aflatoxins from consumption of maize-based products. Results revealed that the estimated average exposure of adults to aflatoxins, from maize consumption, in each of the three countries was between 0.44ng kg(-1) bw day(-1) and 5.59ng kg(-1) bw day(-1). Margin of exposure values for the mean exposure levels, in all three countries, were between 30 and 389. Estimations for hepatocellular carcinoma cases/year/10(5) individuals, depending on the HBsAg+ prevalence, were 0.075-0.098, 0.006-0.008 and 0.020-0.026 for Serbia, Croatia and Greece, respectively.