Total polyphenols from Solanum retroflexum Dun. fruit: extraction and optimization by response surface methodology
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2018
Authors
Karabegović, IvanaMancić, Danijela
Nikolić, Nada
Vukosavljević, Predrag
Stamenković, Sandra
Dajić-Stevanović, Zora
Lazić, Miodrag L.
Article (Published version)
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Total phenolic (TPC), flavonoid (TFC) content and antioxidant activity (AOA) of Solanum retroflexum fruit extracts obtained by conventional extraction with different aqueous ethanol solution (25, 50, 75% v/v), temperatures (20, 40, 60 A degrees C) and extraction time (15, 30 and 45 min) were investigated. The extract obtained by 75% aqueous ethanol at 60 A degrees C after 45 min shows the highest AOA determined by DPPH (EC50 = 60.67 mg/ml) and FRAP (1.55 A mu mol Fe2+/mg) methods. TPC and TFC were in ranges from 63.50 +/- 0.43 to 92.07 +/- 1.07 mg of gallic acid/g of dry extract and from 29.17 +/- 0.35 to 48.22 +/- 0.43 mg of rutin/g of dry extract, respectively. In order to commercialize the extraction of polyphenolic compounds, as the most important group of the plant bioactive compounds, the extraction conditions were optimized by response surface methodology. Under proposed optimum extraction conditions (60 A degrees C, 40.3 min and ethanol concentration of 74.7%) extract with the ...maximal TPC (92.29 mg gallic acid/g of dry extract) could be obtained. The set of the extraction conditions which gave the maximum TPC while simultaneously minimizing the time, energy and ethanol consumption were also proposed (economic extraction conditions). The results confirm that this insufficiently tested fruit represent a good source of polyphenolic compounds and are worthy of further investigation.
Keywords:
Solanum retroflexum / Antioxidant activity / Total phenolic / Optimization / Response surface methodologySource:
Journal of Food Measurement and Characterization, 2018, 12, 3, 1772-1778Publisher:
- Springer, New York
Funding / projects:
- Natural products of plants and lichens: isolation, identification, biological activity and application (RS-MESTD-Basic Research (BR or ON)-172047)
DOI: 10.1007/s11694-018-9792-6
ISSN: 2193-4126
WoS: 000439976200034
Scopus: 2-s2.0-85044538564
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Poljoprivredni fakultetTY - JOUR AU - Karabegović, Ivana AU - Mancić, Danijela AU - Nikolić, Nada AU - Vukosavljević, Predrag AU - Stamenković, Sandra AU - Dajić-Stevanović, Zora AU - Lazić, Miodrag L. PY - 2018 UR - http://aspace.agrif.bg.ac.rs/handle/123456789/4636 AB - Total phenolic (TPC), flavonoid (TFC) content and antioxidant activity (AOA) of Solanum retroflexum fruit extracts obtained by conventional extraction with different aqueous ethanol solution (25, 50, 75% v/v), temperatures (20, 40, 60 A degrees C) and extraction time (15, 30 and 45 min) were investigated. The extract obtained by 75% aqueous ethanol at 60 A degrees C after 45 min shows the highest AOA determined by DPPH (EC50 = 60.67 mg/ml) and FRAP (1.55 A mu mol Fe2+/mg) methods. TPC and TFC were in ranges from 63.50 +/- 0.43 to 92.07 +/- 1.07 mg of gallic acid/g of dry extract and from 29.17 +/- 0.35 to 48.22 +/- 0.43 mg of rutin/g of dry extract, respectively. In order to commercialize the extraction of polyphenolic compounds, as the most important group of the plant bioactive compounds, the extraction conditions were optimized by response surface methodology. Under proposed optimum extraction conditions (60 A degrees C, 40.3 min and ethanol concentration of 74.7%) extract with the maximal TPC (92.29 mg gallic acid/g of dry extract) could be obtained. The set of the extraction conditions which gave the maximum TPC while simultaneously minimizing the time, energy and ethanol consumption were also proposed (economic extraction conditions). The results confirm that this insufficiently tested fruit represent a good source of polyphenolic compounds and are worthy of further investigation. PB - Springer, New York T2 - Journal of Food Measurement and Characterization T1 - Total polyphenols from Solanum retroflexum Dun. fruit: extraction and optimization by response surface methodology EP - 1778 IS - 3 SP - 1772 VL - 12 DO - 10.1007/s11694-018-9792-6 ER -
@article{ author = "Karabegović, Ivana and Mancić, Danijela and Nikolić, Nada and Vukosavljević, Predrag and Stamenković, Sandra and Dajić-Stevanović, Zora and Lazić, Miodrag L.", year = "2018", abstract = "Total phenolic (TPC), flavonoid (TFC) content and antioxidant activity (AOA) of Solanum retroflexum fruit extracts obtained by conventional extraction with different aqueous ethanol solution (25, 50, 75% v/v), temperatures (20, 40, 60 A degrees C) and extraction time (15, 30 and 45 min) were investigated. The extract obtained by 75% aqueous ethanol at 60 A degrees C after 45 min shows the highest AOA determined by DPPH (EC50 = 60.67 mg/ml) and FRAP (1.55 A mu mol Fe2+/mg) methods. TPC and TFC were in ranges from 63.50 +/- 0.43 to 92.07 +/- 1.07 mg of gallic acid/g of dry extract and from 29.17 +/- 0.35 to 48.22 +/- 0.43 mg of rutin/g of dry extract, respectively. In order to commercialize the extraction of polyphenolic compounds, as the most important group of the plant bioactive compounds, the extraction conditions were optimized by response surface methodology. Under proposed optimum extraction conditions (60 A degrees C, 40.3 min and ethanol concentration of 74.7%) extract with the maximal TPC (92.29 mg gallic acid/g of dry extract) could be obtained. The set of the extraction conditions which gave the maximum TPC while simultaneously minimizing the time, energy and ethanol consumption were also proposed (economic extraction conditions). The results confirm that this insufficiently tested fruit represent a good source of polyphenolic compounds and are worthy of further investigation.", publisher = "Springer, New York", journal = "Journal of Food Measurement and Characterization", title = "Total polyphenols from Solanum retroflexum Dun. fruit: extraction and optimization by response surface methodology", pages = "1778-1772", number = "3", volume = "12", doi = "10.1007/s11694-018-9792-6" }
Karabegović, I., Mancić, D., Nikolić, N., Vukosavljević, P., Stamenković, S., Dajić-Stevanović, Z.,& Lazić, M. L.. (2018). Total polyphenols from Solanum retroflexum Dun. fruit: extraction and optimization by response surface methodology. in Journal of Food Measurement and Characterization Springer, New York., 12(3), 1772-1778. https://doi.org/10.1007/s11694-018-9792-6
Karabegović I, Mancić D, Nikolić N, Vukosavljević P, Stamenković S, Dajić-Stevanović Z, Lazić ML. Total polyphenols from Solanum retroflexum Dun. fruit: extraction and optimization by response surface methodology. in Journal of Food Measurement and Characterization. 2018;12(3):1772-1778. doi:10.1007/s11694-018-9792-6 .
Karabegović, Ivana, Mancić, Danijela, Nikolić, Nada, Vukosavljević, Predrag, Stamenković, Sandra, Dajić-Stevanović, Zora, Lazić, Miodrag L., "Total polyphenols from Solanum retroflexum Dun. fruit: extraction and optimization by response surface methodology" in Journal of Food Measurement and Characterization, 12, no. 3 (2018):1772-1778, https://doi.org/10.1007/s11694-018-9792-6 . .