Curcumin and its derivates are well-known for their different biological activities including antibacterial. On the other hand there are controversial reports concerning the antibacterial potential of graphene and, in particular, graphene oxide. In this study we have reported for the first time the antibacterial activity of curcumin/graphene nanomesh hybrids under ambient light conditions. The graphene nanomesh was synthesized by electrochemical exfoliation of highly oriented pyrolytic graphite in 1 M solution of ammonium persulfate and further functionalized by curcumin. Identical values of minimum inhibitory concentration (1 mg mL(-1)) were determined for pure curcumin and curcumin/graphene nanomesh hybrids toward Staphylococcus aureus. All tested samples had more pronounced antibacterial activity against Gram positive bacteria, Staphylococcus aureus compared to Escherichia coli as a representative of Gram negative strains. The poor antibacterial potential of exfoliated graphene impr...oves significantly by the functionalization with curcumin, which allows for its usage as a antibacterial coating.
Source:
RSC Advances, 2017, 7, 57, 36081-36092
Publisher:
Royal Soc Chemistry, Cambridge
Funding / projects:
multilateral scientific and technological cooperation in the Danube region [DS021]
TY - JOUR
AU - Marković, Z.M.
AU - Kepić, Dejan P.
AU - Matijašević, Danka
AU - Pavlović, Vladimir
AU - Jovanović, S.P.
AU - Stanković, N.K.
AU - Milivojević, Dušan D.
AU - Spitalsky, Z.
AU - Holclajtner-Antunović, Ivanka
AU - Bajuk-Bogdanović, Danica
AU - Nikšić, Miomir
AU - Todorović-Marković, Biljana
PY - 2017
UR - http://aspace.agrif.bg.ac.rs/handle/123456789/4467
AB - Curcumin and its derivates are well-known for their different biological activities including antibacterial. On the other hand there are controversial reports concerning the antibacterial potential of graphene and, in particular, graphene oxide. In this study we have reported for the first time the antibacterial activity of curcumin/graphene nanomesh hybrids under ambient light conditions. The graphene nanomesh was synthesized by electrochemical exfoliation of highly oriented pyrolytic graphite in 1 M solution of ammonium persulfate and further functionalized by curcumin. Identical values of minimum inhibitory concentration (1 mg mL(-1)) were determined for pure curcumin and curcumin/graphene nanomesh hybrids toward Staphylococcus aureus. All tested samples had more pronounced antibacterial activity against Gram positive bacteria, Staphylococcus aureus compared to Escherichia coli as a representative of Gram negative strains. The poor antibacterial potential of exfoliated graphene improves significantly by the functionalization with curcumin, which allows for its usage as a antibacterial coating.
PB - Royal Soc Chemistry, Cambridge
T2 - RSC Advances
T1 - Ambient light induced antibacterial action of curcumin/graphene nanomesh hybrids
EP - 36092
IS - 57
SP - 36081
VL - 7
DO - 10.1039/c7ra05027e
ER -
@article{
author = "Marković, Z.M. and Kepić, Dejan P. and Matijašević, Danka and Pavlović, Vladimir and Jovanović, S.P. and Stanković, N.K. and Milivojević, Dušan D. and Spitalsky, Z. and Holclajtner-Antunović, Ivanka and Bajuk-Bogdanović, Danica and Nikšić, Miomir and Todorović-Marković, Biljana",
year = "2017",
abstract = "Curcumin and its derivates are well-known for their different biological activities including antibacterial. On the other hand there are controversial reports concerning the antibacterial potential of graphene and, in particular, graphene oxide. In this study we have reported for the first time the antibacterial activity of curcumin/graphene nanomesh hybrids under ambient light conditions. The graphene nanomesh was synthesized by electrochemical exfoliation of highly oriented pyrolytic graphite in 1 M solution of ammonium persulfate and further functionalized by curcumin. Identical values of minimum inhibitory concentration (1 mg mL(-1)) were determined for pure curcumin and curcumin/graphene nanomesh hybrids toward Staphylococcus aureus. All tested samples had more pronounced antibacterial activity against Gram positive bacteria, Staphylococcus aureus compared to Escherichia coli as a representative of Gram negative strains. The poor antibacterial potential of exfoliated graphene improves significantly by the functionalization with curcumin, which allows for its usage as a antibacterial coating.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "RSC Advances",
title = "Ambient light induced antibacterial action of curcumin/graphene nanomesh hybrids",
pages = "36092-36081",
number = "57",
volume = "7",
doi = "10.1039/c7ra05027e"
}
Marković, Z.M., Kepić, D. P., Matijašević, D., Pavlović, V., Jovanović, S.P., Stanković, N.K., Milivojević, D. D., Spitalsky, Z., Holclajtner-Antunović, I., Bajuk-Bogdanović, D., Nikšić, M.,& Todorović-Marković, B.. (2017). Ambient light induced antibacterial action of curcumin/graphene nanomesh hybrids. in RSC Advances
Royal Soc Chemistry, Cambridge., 7(57), 36081-36092.
https://doi.org/10.1039/c7ra05027e
Marković Z, Kepić DP, Matijašević D, Pavlović V, Jovanović S, Stanković N, Milivojević DD, Spitalsky Z, Holclajtner-Antunović I, Bajuk-Bogdanović D, Nikšić M, Todorović-Marković B. Ambient light induced antibacterial action of curcumin/graphene nanomesh hybrids. in RSC Advances. 2017;7(57):36081-36092.
doi:10.1039/c7ra05027e .
