Fourteen mono- and bis-carbohydrazone ligands have been synthesized and characterized. Antioxidant activity of the substances was investigated together with possible (E)/(Z) isomerization, and explained on the most active antioxidant compound 4 in various dimethyl sulphoxide-water mixtures. The addition of water to the system was involved in the formation of hydrated molecules which was confirmed in NMR after the addition of D2O. The ligands were tested in vitro against Gram-positive and Gram-negative bacteria and fungi, and their activity was discussed in relation to the structure of investigated carbohydrazone.
TY - JOUR
AU - Božić, Aleksandra R.
AU - Filipović, Nenad
AU - Novaković, Irena
AU - Bjelogrlić, Snežana
AU - Nikolić, Jasmina B.
AU - Drmanić, Sasa Z.
AU - Marinković, Aleksandar D.
PY - 2017
UR - http://aspace.agrif.bg.ac.rs/handle/123456789/4456
AB - Fourteen mono- and bis-carbohydrazone ligands have been synthesized and characterized. Antioxidant activity of the substances was investigated together with possible (E)/(Z) isomerization, and explained on the most active antioxidant compound 4 in various dimethyl sulphoxide-water mixtures. The addition of water to the system was involved in the formation of hydrated molecules which was confirmed in NMR after the addition of D2O. The ligands were tested in vitro against Gram-positive and Gram-negative bacteria and fungi, and their activity was discussed in relation to the structure of investigated carbohydrazone.
PB - Srpsko hemijsko društvo, Beograd
T2 - JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
T1 - Synthesis, antioxidant and antimicrobial activity of carbohydrazones
EP - 508
IS - 5
SP - 495
VL - 82
DO - 10.2298/JSC161220045B
ER -
@article{
author = "Božić, Aleksandra R. and Filipović, Nenad and Novaković, Irena and Bjelogrlić, Snežana and Nikolić, Jasmina B. and Drmanić, Sasa Z. and Marinković, Aleksandar D.",
year = "2017",
abstract = "Fourteen mono- and bis-carbohydrazone ligands have been synthesized and characterized. Antioxidant activity of the substances was investigated together with possible (E)/(Z) isomerization, and explained on the most active antioxidant compound 4 in various dimethyl sulphoxide-water mixtures. The addition of water to the system was involved in the formation of hydrated molecules which was confirmed in NMR after the addition of D2O. The ligands were tested in vitro against Gram-positive and Gram-negative bacteria and fungi, and their activity was discussed in relation to the structure of investigated carbohydrazone.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "JOURNAL OF THE SERBIAN CHEMICAL SOCIETY",
title = "Synthesis, antioxidant and antimicrobial activity of carbohydrazones",
pages = "508-495",
number = "5",
volume = "82",
doi = "10.2298/JSC161220045B"
}
Božić, A. R., Filipović, N., Novaković, I., Bjelogrlić, S., Nikolić, J. B., Drmanić, S. Z.,& Marinković, A. D.. (2017). Synthesis, antioxidant and antimicrobial activity of carbohydrazones. in JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
Srpsko hemijsko društvo, Beograd., 82(5), 495-508.
https://doi.org/10.2298/JSC161220045B
Božić AR, Filipović N, Novaković I, Bjelogrlić S, Nikolić JB, Drmanić SZ, Marinković AD. Synthesis, antioxidant and antimicrobial activity of carbohydrazones. in JOURNAL OF THE SERBIAN CHEMICAL SOCIETY. 2017;82(5):495-508.
doi:10.2298/JSC161220045B .
Božić, Aleksandra R., Filipović, Nenad, Novaković, Irena, Bjelogrlić, Snežana, Nikolić, Jasmina B., Drmanić, Sasa Z., Marinković, Aleksandar D., "Synthesis, antioxidant and antimicrobial activity of carbohydrazones" in JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 82, no. 5 (2017):495-508,
https://doi.org/10.2298/JSC161220045B . .
