Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites
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2017
Authors
Malagurski, IvanaLević, Steva

Pantić, Milena

Matijasević, Danka
Mitrić, Miodrag

Pavlović, Vladimir

Dimitrijević-Branković, Suzana

Article (Published version)

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New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents a'good strategy for designing multifunctional biomaterials for potential biomedical applications.
Keywords:
Zinc / Alginate / Nanocomposite / Biomineralization / Antimicrobial activitySource:
Carbohydrate Polymers, 2017, 165, 313-321Publisher:
- Elsevier Sci Ltd, Oxford
Funding / projects:
- Synthesis, processing and applications of nanostructured multifunctional materials with defined properties (RS-45019)
- Directed synthesis, structure and properties of multifunctional materials (RS-172057)
DOI: 10.1016/j.carbpol.2017.02.064
ISSN: 0144-8617
PubMed: 28363555
WoS: 000399261900035
Scopus: 2-s2.0-85013763459
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Poljoprivredni fakultetTY - JOUR AU - Malagurski, Ivana AU - Lević, Steva AU - Pantić, Milena AU - Matijasević, Danka AU - Mitrić, Miodrag AU - Pavlović, Vladimir AU - Dimitrijević-Branković, Suzana PY - 2017 UR - http://aspace.agrif.bg.ac.rs/handle/123456789/4336 AB - New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents a'good strategy for designing multifunctional biomaterials for potential biomedical applications. PB - Elsevier Sci Ltd, Oxford T2 - Carbohydrate Polymers T1 - Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites EP - 321 SP - 313 VL - 165 DO - 10.1016/j.carbpol.2017.02.064 ER -
@article{ author = "Malagurski, Ivana and Lević, Steva and Pantić, Milena and Matijasević, Danka and Mitrić, Miodrag and Pavlović, Vladimir and Dimitrijević-Branković, Suzana", year = "2017", abstract = "New bioactive and antimicrobial biomaterials were produced by alginate-mediated biomineralization with Zn-mineral phase. The synthesis procedure is simple, cost-effective and resulted in. two different Zn-mineralized alginate nanocomposites, Zn-carbonate/Zn-alginate and Zn-phosphate/Zn-alginate. The presence of Zn-mineral phase and its type, have significantly affected nanocomposite morphology, stability, total metallic loading and potential to release Zn(II) in physiological environment. Antimicrobial experiments showed that both types of Zn-mineralized nanocomposites exhibit strong antimicrobial effect against Escherichia coli, Staphylococcus aureus and Candida albicans. These results suggest that alginate biomineralization, where minerals are salts of essential metallic ions like Zn(II), represents a'good strategy for designing multifunctional biomaterials for potential biomedical applications.", publisher = "Elsevier Sci Ltd, Oxford", journal = "Carbohydrate Polymers", title = "Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites", pages = "321-313", volume = "165", doi = "10.1016/j.carbpol.2017.02.064" }
Malagurski, I., Lević, S., Pantić, M., Matijasević, D., Mitrić, M., Pavlović, V.,& Dimitrijević-Branković, S.. (2017). Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites. in Carbohydrate Polymers Elsevier Sci Ltd, Oxford., 165, 313-321. https://doi.org/10.1016/j.carbpol.2017.02.064
Malagurski I, Lević S, Pantić M, Matijasević D, Mitrić M, Pavlović V, Dimitrijević-Branković S. Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites. in Carbohydrate Polymers. 2017;165:313-321. doi:10.1016/j.carbpol.2017.02.064 .
Malagurski, Ivana, Lević, Steva, Pantić, Milena, Matijasević, Danka, Mitrić, Miodrag, Pavlović, Vladimir, Dimitrijević-Branković, Suzana, "Synthesis and antimicrobial properties of Zn-mineralized alginate nanocomposites" in Carbohydrate Polymers, 165 (2017):313-321, https://doi.org/10.1016/j.carbpol.2017.02.064 . .