TY  - JOUR
AU  - Veljković, Bojana
AU  - Djordjević, Nataša
AU  - Dolicanin, Zana
AU  - Licina, Braho
AU  - Topuzović, Marina
AU  - Stanković, Milan
AU  - Zlatić, Nenad
AU  - Dajić-Stevanović, Zora
PY  - 2019
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/5130
AB  - In this study the leaves and fruits of wild raspberry (Rubus idaeus L.) populations from the central Balkan region were examined to determine the level of secondary metabolites and related antioxidant activity, as well as biological activity, upon existing ethnobotanical evidence, primarily linked to gastrointestinal disorders. The values obtained for total phenols ranged from 59.68 to 96.83 mg GA g(-1) and 24.29 to 38.71 mg GA g(-1) in leaf and fruit extracts, respectively. The highest values of tannins and anthocyanins were determined for leaf extracts from a population of east Serbia at a level of 1.27 mg mL(-1) and 9.00 mg mL(-1). Antioxidant activity was evaluated by measuring the scavenging capacity of the extracts on DPPH. Higher antioxidant activity was detected in the leaf extracts than in the fruit extracts. Leaf and fruit extract were the most effective against Escherichia coli (ATCC 8739). Anticancer activity was studied on a human colorectal cancer cell line HCT-116. Leaf extracts exhibited anticancer activity with IC50/24 h 162.38 mu g mL(-1) and IC50/48 h 95.69 mu g mL(-1). Wild raspberry leaf and fruit extracts contain numerous secondary metabolites providing marked antioxidant, antimicrobial and anticancer activity.
PB  - Academic Press
T2  - Notulae Botanicae Horti Agrobotanici Cluj-Napoca
T1  - Antioxidant and Anticancer Properties of Leaf and Fruit Extracts of the Wild Raspberry (Rubus idaeus L.)
EP  - 367
IS  - 2
SP  - 359
VL  - 47
DO  - 10.15835/nbha47111274
ER  - 

@article{
author = "Veljković, Bojana and Djordjević, Nataša and Dolicanin, Zana and Licina, Braho and Topuzović, Marina and Stanković, Milan and Zlatić, Nenad and Dajić-Stevanović, Zora",
year = "2019",
abstract = "In this study the leaves and fruits of wild raspberry (Rubus idaeus L.) populations from the central Balkan region were examined to determine the level of secondary metabolites and related antioxidant activity, as well as biological activity, upon existing ethnobotanical evidence, primarily linked to gastrointestinal disorders. The values obtained for total phenols ranged from 59.68 to 96.83 mg GA g(-1) and 24.29 to 38.71 mg GA g(-1) in leaf and fruit extracts, respectively. The highest values of tannins and anthocyanins were determined for leaf extracts from a population of east Serbia at a level of 1.27 mg mL(-1) and 9.00 mg mL(-1). Antioxidant activity was evaluated by measuring the scavenging capacity of the extracts on DPPH. Higher antioxidant activity was detected in the leaf extracts than in the fruit extracts. Leaf and fruit extract were the most effective against Escherichia coli (ATCC 8739). Anticancer activity was studied on a human colorectal cancer cell line HCT-116. Leaf extracts exhibited anticancer activity with IC50/24 h 162.38 mu g mL(-1) and IC50/48 h 95.69 mu g mL(-1). Wild raspberry leaf and fruit extracts contain numerous secondary metabolites providing marked antioxidant, antimicrobial and anticancer activity.",
publisher = "Academic Press",
journal = "Notulae Botanicae Horti Agrobotanici Cluj-Napoca",
title = "Antioxidant and Anticancer Properties of Leaf and Fruit Extracts of the Wild Raspberry (Rubus idaeus L.)",
pages = "367-359",
number = "2",
volume = "47",
doi = "10.15835/nbha47111274"
}

Veljković, B., Djordjević, N., Dolicanin, Z., Licina, B., Topuzović, M., Stanković, M., Zlatić, N.,& Dajić-Stevanović, Z.. (2019). Antioxidant and Anticancer Properties of Leaf and Fruit Extracts of the Wild Raspberry (Rubus idaeus L.). in Notulae Botanicae Horti Agrobotanici Cluj-Napoca
Academic Press., 47(2), 359-367.
https://doi.org/10.15835/nbha47111274

Veljković B, Djordjević N, Dolicanin Z, Licina B, Topuzović M, Stanković M, Zlatić N, Dajić-Stevanović Z. Antioxidant and Anticancer Properties of Leaf and Fruit Extracts of the Wild Raspberry (Rubus idaeus L.). in Notulae Botanicae Horti Agrobotanici Cluj-Napoca. 2019;47(2):359-367.
doi:10.15835/nbha47111274 .

Veljković, Bojana, Djordjević, Nataša, Dolicanin, Zana, Licina, Braho, Topuzović, Marina, Stanković, Milan, Zlatić, Nenad, Dajić-Stevanović, Zora, "Antioxidant and Anticancer Properties of Leaf and Fruit Extracts of the Wild Raspberry (Rubus idaeus L.)" in Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 47, no. 2 (2019):359-367,
https://doi.org/10.15835/nbha47111274 . .

TY  - JOUR
AU  - Veljković, Bojana
AU  - Jakovljević, Violeta
AU  - Stanković, Milan
AU  - Dajić-Stevanović, Zora
PY  - 2019
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4924
AB  - The current study investigated and compared phytochemical and antioxidant activity of fresh fruit and some traditional products of Rubus idaeus grown in mountain region of Serbia. The total organic acid, total sugar content, total phenolics, flavonoids, tannins, anthocyanins and vitamin C were evaluated. The antioxidant activities were evaluated using two antioxidant systems 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). The fresh fruit contained highest amount of vitamin C (46.62 mg AA g(-1)) and total organic acids (882.22 mg CA g(-1)). The sweet preserve had highest content of total phenolics (200.83 mg GA g(-1)), flavonoids (12.85 mg RU g(-1)) and tannins (39.11 mg g(-1)). The juice had the highest total anthocyanin content (107.22 mu g mL(-1)) and total sugar content (25 degrees Brix). The best antioxidant activity in ABTS assay had juice (IC50 = 4.87 mu mol TE g(-1)), followed by sweet preserve (IC50 = 5.14 mu mol TE g(-1)), almost identical to standard gallic acid. In the DPPH free radical scavenging assay, sweet fruit preserve showed significant better antioxidant activity (IC50 = 41.27 mu g mL(-1)) compared to juice (IC50 = 106.07 mu g mL(-1)) and fresh fruit (IC50 = 294.79 mu g mL(-1)). Our results indicated promising perspectives for usage of R. idaeus fresh fruits and traditional products studied with considerable levels of vitamin C, bioactive compounds and antioxidant activity.
PB  - Univ Agr Sci & Veterinary Med Cluj-Napoca, Cluj-Napoca
T2  - NOTULAE BOTANICAE HORTI AGROBOTANICI CLUJ-NAPOCA
T1  - Phytochemical and Antioxidant Properties of Fresh Fruits and Some Traditional Products of Wild Grown Raspberry (Rubus idaeus L.)
EP  - 573
IS  - 3
SP  - 565
VL  - 47
DO  - 10.15835/nbha47311465
ER  - 

@article{
author = "Veljković, Bojana and Jakovljević, Violeta and Stanković, Milan and Dajić-Stevanović, Zora",
year = "2019",
abstract = "The current study investigated and compared phytochemical and antioxidant activity of fresh fruit and some traditional products of Rubus idaeus grown in mountain region of Serbia. The total organic acid, total sugar content, total phenolics, flavonoids, tannins, anthocyanins and vitamin C were evaluated. The antioxidant activities were evaluated using two antioxidant systems 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). The fresh fruit contained highest amount of vitamin C (46.62 mg AA g(-1)) and total organic acids (882.22 mg CA g(-1)). The sweet preserve had highest content of total phenolics (200.83 mg GA g(-1)), flavonoids (12.85 mg RU g(-1)) and tannins (39.11 mg g(-1)). The juice had the highest total anthocyanin content (107.22 mu g mL(-1)) and total sugar content (25 degrees Brix). The best antioxidant activity in ABTS assay had juice (IC50 = 4.87 mu mol TE g(-1)), followed by sweet preserve (IC50 = 5.14 mu mol TE g(-1)), almost identical to standard gallic acid. In the DPPH free radical scavenging assay, sweet fruit preserve showed significant better antioxidant activity (IC50 = 41.27 mu g mL(-1)) compared to juice (IC50 = 106.07 mu g mL(-1)) and fresh fruit (IC50 = 294.79 mu g mL(-1)). Our results indicated promising perspectives for usage of R. idaeus fresh fruits and traditional products studied with considerable levels of vitamin C, bioactive compounds and antioxidant activity.",
publisher = "Univ Agr Sci & Veterinary Med Cluj-Napoca, Cluj-Napoca",
journal = "NOTULAE BOTANICAE HORTI AGROBOTANICI CLUJ-NAPOCA",
title = "Phytochemical and Antioxidant Properties of Fresh Fruits and Some Traditional Products of Wild Grown Raspberry (Rubus idaeus L.)",
pages = "573-565",
number = "3",
volume = "47",
doi = "10.15835/nbha47311465"
}

Veljković, B., Jakovljević, V., Stanković, M.,& Dajić-Stevanović, Z.. (2019). Phytochemical and Antioxidant Properties of Fresh Fruits and Some Traditional Products of Wild Grown Raspberry (Rubus idaeus L.). in NOTULAE BOTANICAE HORTI AGROBOTANICI CLUJ-NAPOCA
Univ Agr Sci & Veterinary Med Cluj-Napoca, Cluj-Napoca., 47(3), 565-573.
https://doi.org/10.15835/nbha47311465

Veljković B, Jakovljević V, Stanković M, Dajić-Stevanović Z. Phytochemical and Antioxidant Properties of Fresh Fruits and Some Traditional Products of Wild Grown Raspberry (Rubus idaeus L.). in NOTULAE BOTANICAE HORTI AGROBOTANICI CLUJ-NAPOCA. 2019;47(3):565-573.
doi:10.15835/nbha47311465 .

Veljković, Bojana, Jakovljević, Violeta, Stanković, Milan, Dajić-Stevanović, Zora, "Phytochemical and Antioxidant Properties of Fresh Fruits and Some Traditional Products of Wild Grown Raspberry (Rubus idaeus L.)" in NOTULAE BOTANICAE HORTI AGROBOTANICI CLUJ-NAPOCA, 47, no. 3 (2019):565-573,
https://doi.org/10.15835/nbha47311465 . .