TY  - JOUR
AU  - Volić, Mina
AU  - Pajić-Lijaković, Ivana
AU  - Djordjević, Verica B.
AU  - Knežević-Jugović, Zorica
AU  - Pećinar, Ilinka
AU  - Dajić-Stevanović, Zora
AU  - Veljović, Djordje
AU  - Hadnadjev, Miroslav
AU  - Bugarski, Branko
PY  - 2018
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4665
AB  - Preparation of alginate-soy protein isolate (AL/SPI) complex beads containing essential oil of thyme was carried out by emulsification of thyme oil in aqueous sodium alginate solution blended with SPI solution, followed by atomization via electrostatic extrusion and gelification with calcium ions. The process parameters were optimized by variation of the alginate (1-2.5 wt.%) and SPI (0-1.5 wt.%) concentrations. Dry alginate-SPI particles exhibited wrinkle surface while shape distortion of hydrogel beads occurred with >= 1.5 wt.% alginate concentration, whereas SPI induced reduction of the particle size. Encapsulation efficiency of 72-80 % based on total polyphenols was achieved. In SGF the samples exhibited oil release of 42-55 % (due to matrix shrinkage and proteins degradation by pepsin activity), while the rest was delivered in SIF within 2.5 h simultaneously with swelling and degradation of the matrix.
PB  - Elsevier Sci Ltd, Oxford
T2  - Carbohydrate Polymers
T1  - Alginate/soy protein system for essential oil encapsulation with intestinal delivery
EP  - 24
SP  - 15
VL  - 200
DO  - 10.1016/j.carbpol.2018.07.033
ER  - 

@article{
author = "Volić, Mina and Pajić-Lijaković, Ivana and Djordjević, Verica B. and Knežević-Jugović, Zorica and Pećinar, Ilinka and Dajić-Stevanović, Zora and Veljović, Djordje and Hadnadjev, Miroslav and Bugarski, Branko",
year = "2018",
abstract = "Preparation of alginate-soy protein isolate (AL/SPI) complex beads containing essential oil of thyme was carried out by emulsification of thyme oil in aqueous sodium alginate solution blended with SPI solution, followed by atomization via electrostatic extrusion and gelification with calcium ions. The process parameters were optimized by variation of the alginate (1-2.5 wt.%) and SPI (0-1.5 wt.%) concentrations. Dry alginate-SPI particles exhibited wrinkle surface while shape distortion of hydrogel beads occurred with >= 1.5 wt.% alginate concentration, whereas SPI induced reduction of the particle size. Encapsulation efficiency of 72-80 % based on total polyphenols was achieved. In SGF the samples exhibited oil release of 42-55 % (due to matrix shrinkage and proteins degradation by pepsin activity), while the rest was delivered in SIF within 2.5 h simultaneously with swelling and degradation of the matrix.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Carbohydrate Polymers",
title = "Alginate/soy protein system for essential oil encapsulation with intestinal delivery",
pages = "24-15",
volume = "200",
doi = "10.1016/j.carbpol.2018.07.033"
}

Volić, M., Pajić-Lijaković, I., Djordjević, V. B., Knežević-Jugović, Z., Pećinar, I., Dajić-Stevanović, Z., Veljović, D., Hadnadjev, M.,& Bugarski, B.. (2018). Alginate/soy protein system for essential oil encapsulation with intestinal delivery. in Carbohydrate Polymers
Elsevier Sci Ltd, Oxford., 200, 15-24.
https://doi.org/10.1016/j.carbpol.2018.07.033

Volić M, Pajić-Lijaković I, Djordjević VB, Knežević-Jugović Z, Pećinar I, Dajić-Stevanović Z, Veljović D, Hadnadjev M, Bugarski B. Alginate/soy protein system for essential oil encapsulation with intestinal delivery. in Carbohydrate Polymers. 2018;200:15-24.
doi:10.1016/j.carbpol.2018.07.033 .

Volić, Mina, Pajić-Lijaković, Ivana, Djordjević, Verica B., Knežević-Jugović, Zorica, Pećinar, Ilinka, Dajić-Stevanović, Zora, Veljović, Djordje, Hadnadjev, Miroslav, Bugarski, Branko, "Alginate/soy protein system for essential oil encapsulation with intestinal delivery" in Carbohydrate Polymers, 200 (2018):15-24,
https://doi.org/10.1016/j.carbpol.2018.07.033 . .

TY  - JOUR
AU  - Tomić, Nataša Z.
AU  - Marinković, Aleksandar D.
AU  - Veljović, Djordje
AU  - Trifković, Kata
AU  - Lević, Steva
AU  - Radojević, Vesna
AU  - Jancić-Heinemann, Radmila
PY  - 2018
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4749
AB  - Mechanical, morphological and thermal properties of optical fiber adhesives, based on poly(ethylene-co-vinyl acetate) (EVA) with 18 and 40% of vinyl acetate, polymer blend of EVA/poly(methyl methacrylate) (PMMA), and graft polymer, raw EVA-g-PMMA, prepared via in situ free radical polymerization, were studied. Extraction of PMMA homopolymer from raw EVA-g-PMMA produced purified EVA-g-PMMA, which enable quantitative determination of graft initiating centers by NMR spectroscopy. FTIR and image analysis allowed determination of the graft content/level in purified EVA-g-PMMA. Grafting effect to compatibilization efficiency in EVA-g-PMMA was monitored by image analysis of gelation processes and determination of wetting angle. Single lap joint of adhesives/optical fibers were subjected to adhesive testing before and after aging on 60 degrees C for 60 h and 120 h. Thermogravimetry coupled with mass spectrometry showed different thermal stability and degradation pathways of adhesives, and reduced the degree of deacetylation of thermally treated EVA-g-PMMA adhesive. DSC analysis showed higher thermal stability of EVA-g-PMMA adhesive. Better mechanical properties of EVA-g-PMMA, i.e. 62.4% higher Charpy impact strength value in relation to EVA, was obtained.
PB  - Elsevier Sci Ltd, Oxford
T2  - International Journal of Adhesion and Adhesives
T1  - A new approach to compatibilization study of EVA/PMMA polymer blend used as an optical fibers adhesive: Mechanical, morphological and thermal properties
EP  - 20
SP  - 11
VL  - 81
DO  - 10.1016/j.ijadhadh.2017.11.002
ER  - 

@article{
author = "Tomić, Nataša Z. and Marinković, Aleksandar D. and Veljović, Djordje and Trifković, Kata and Lević, Steva and Radojević, Vesna and Jancić-Heinemann, Radmila",
year = "2018",
abstract = "Mechanical, morphological and thermal properties of optical fiber adhesives, based on poly(ethylene-co-vinyl acetate) (EVA) with 18 and 40% of vinyl acetate, polymer blend of EVA/poly(methyl methacrylate) (PMMA), and graft polymer, raw EVA-g-PMMA, prepared via in situ free radical polymerization, were studied. Extraction of PMMA homopolymer from raw EVA-g-PMMA produced purified EVA-g-PMMA, which enable quantitative determination of graft initiating centers by NMR spectroscopy. FTIR and image analysis allowed determination of the graft content/level in purified EVA-g-PMMA. Grafting effect to compatibilization efficiency in EVA-g-PMMA was monitored by image analysis of gelation processes and determination of wetting angle. Single lap joint of adhesives/optical fibers were subjected to adhesive testing before and after aging on 60 degrees C for 60 h and 120 h. Thermogravimetry coupled with mass spectrometry showed different thermal stability and degradation pathways of adhesives, and reduced the degree of deacetylation of thermally treated EVA-g-PMMA adhesive. DSC analysis showed higher thermal stability of EVA-g-PMMA adhesive. Better mechanical properties of EVA-g-PMMA, i.e. 62.4% higher Charpy impact strength value in relation to EVA, was obtained.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "International Journal of Adhesion and Adhesives",
title = "A new approach to compatibilization study of EVA/PMMA polymer blend used as an optical fibers adhesive: Mechanical, morphological and thermal properties",
pages = "20-11",
volume = "81",
doi = "10.1016/j.ijadhadh.2017.11.002"
}

Tomić, N. Z., Marinković, A. D., Veljović, D., Trifković, K., Lević, S., Radojević, V.,& Jancić-Heinemann, R.. (2018). A new approach to compatibilization study of EVA/PMMA polymer blend used as an optical fibers adhesive: Mechanical, morphological and thermal properties. in International Journal of Adhesion and Adhesives
Elsevier Sci Ltd, Oxford., 81, 11-20.
https://doi.org/10.1016/j.ijadhadh.2017.11.002

Tomić NZ, Marinković AD, Veljović D, Trifković K, Lević S, Radojević V, Jancić-Heinemann R. A new approach to compatibilization study of EVA/PMMA polymer blend used as an optical fibers adhesive: Mechanical, morphological and thermal properties. in International Journal of Adhesion and Adhesives. 2018;81:11-20.
doi:10.1016/j.ijadhadh.2017.11.002 .

Tomić, Nataša Z., Marinković, Aleksandar D., Veljović, Djordje, Trifković, Kata, Lević, Steva, Radojević, Vesna, Jancić-Heinemann, Radmila, "A new approach to compatibilization study of EVA/PMMA polymer blend used as an optical fibers adhesive: Mechanical, morphological and thermal properties" in International Journal of Adhesion and Adhesives, 81 (2018):11-20,
https://doi.org/10.1016/j.ijadhadh.2017.11.002 . .

TY  - JOUR
AU  - Kostić, Ivana T.
AU  - Ilić, Vesna Lj.
AU  - Djordjević, Verica
AU  - Bukara, Katarina M.
AU  - Mojsilović, Slavko B.
AU  - Nedović, Viktor
AU  - Bugarski, Diana S.
AU  - Veljović, Djordje
AU  - Misić, Danijela M.
AU  - Bugarski, Branko
PY  - 2014
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3454
AB  - The present study was aimed at investigating the effect of isolation process-gradual hypotonic hemolysis on chosen parameters of the erythrocyte membranes (ghosts) originating from bovine and porcine slaughterhouse blood. The estimation of the gradual hypotonic hemolysis as a drug loading procedure for the erythrocyte ghosts was performed as well. Based on the results derived from analysis of the osmotic properties of the erythrocytes, the gradual hemolysis was performed with high volume of erythrocytes and 35 mM hypotonic sodium-phosphate/NaCl, enabling >90% of hemolysis for both types of erythrocytes. Detailed insight into ghosts' morphology by field emission-scanning electron microscopy revealed a distortion from erythrocyte shape and an altered surface texture with increased bilayer curvature for both samples. Compared to erythrocytes, an average diameter of ghosts from both type of erythrocytes decreased for only about 10%. The reported unidispersity of the isolated ghosts is of great importance for their potential application as vehicles of active compounds. Gradual hemolysis did not lead to substantial loss of cholesterol and membrane/cytoskeleton proteins. This result indicated the ghosts' possibility to mimic the chemical and structural anisotropic environment of in vivo cell membranes, which is of significance for drug diffusion and partition coefficients. Induced shift of phosphatidylserine to external surface of the ghosts demonstrated their potential application as vehicles for targeted drug delivery to cells of reticuloendothelial system. Ultra high-performance liquid chromatography and Fourier transform infrared spectroscopy revealed the presence of a drug model - dexamethasone-sodium phosphate, and its interaction with structural components in both types of erythrocyte ghosts.
PB  - Elsevier, Amsterdam
T2  - Colloids and Surfaces B-Biointerfaces
T1  - Erythrocyte membranes from slaughterhouse blood as potential drug vehicles: Isolation by gradual hypotonic hemolysis and biochemical and morphological characterization
EP  - 259
SP  - 250
VL  - 122
DO  - 10.1016/j.colsurfb.2014.06.043
ER  - 

@article{
author = "Kostić, Ivana T. and Ilić, Vesna Lj. and Djordjević, Verica and Bukara, Katarina M. and Mojsilović, Slavko B. and Nedović, Viktor and Bugarski, Diana S. and Veljović, Djordje and Misić, Danijela M. and Bugarski, Branko",
year = "2014",
abstract = "The present study was aimed at investigating the effect of isolation process-gradual hypotonic hemolysis on chosen parameters of the erythrocyte membranes (ghosts) originating from bovine and porcine slaughterhouse blood. The estimation of the gradual hypotonic hemolysis as a drug loading procedure for the erythrocyte ghosts was performed as well. Based on the results derived from analysis of the osmotic properties of the erythrocytes, the gradual hemolysis was performed with high volume of erythrocytes and 35 mM hypotonic sodium-phosphate/NaCl, enabling >90% of hemolysis for both types of erythrocytes. Detailed insight into ghosts' morphology by field emission-scanning electron microscopy revealed a distortion from erythrocyte shape and an altered surface texture with increased bilayer curvature for both samples. Compared to erythrocytes, an average diameter of ghosts from both type of erythrocytes decreased for only about 10%. The reported unidispersity of the isolated ghosts is of great importance for their potential application as vehicles of active compounds. Gradual hemolysis did not lead to substantial loss of cholesterol and membrane/cytoskeleton proteins. This result indicated the ghosts' possibility to mimic the chemical and structural anisotropic environment of in vivo cell membranes, which is of significance for drug diffusion and partition coefficients. Induced shift of phosphatidylserine to external surface of the ghosts demonstrated their potential application as vehicles for targeted drug delivery to cells of reticuloendothelial system. Ultra high-performance liquid chromatography and Fourier transform infrared spectroscopy revealed the presence of a drug model - dexamethasone-sodium phosphate, and its interaction with structural components in both types of erythrocyte ghosts.",
publisher = "Elsevier, Amsterdam",
journal = "Colloids and Surfaces B-Biointerfaces",
title = "Erythrocyte membranes from slaughterhouse blood as potential drug vehicles: Isolation by gradual hypotonic hemolysis and biochemical and morphological characterization",
pages = "259-250",
volume = "122",
doi = "10.1016/j.colsurfb.2014.06.043"
}

Kostić, I. T., Ilić, V. Lj., Djordjević, V., Bukara, K. M., Mojsilović, S. B., Nedović, V., Bugarski, D. S., Veljović, D., Misić, D. M.,& Bugarski, B.. (2014). Erythrocyte membranes from slaughterhouse blood as potential drug vehicles: Isolation by gradual hypotonic hemolysis and biochemical and morphological characterization. in Colloids and Surfaces B-Biointerfaces
Elsevier, Amsterdam., 122, 250-259.
https://doi.org/10.1016/j.colsurfb.2014.06.043

Kostić IT, Ilić VL, Djordjević V, Bukara KM, Mojsilović SB, Nedović V, Bugarski DS, Veljović D, Misić DM, Bugarski B. Erythrocyte membranes from slaughterhouse blood as potential drug vehicles: Isolation by gradual hypotonic hemolysis and biochemical and morphological characterization. in Colloids and Surfaces B-Biointerfaces. 2014;122:250-259.
doi:10.1016/j.colsurfb.2014.06.043 .

Kostić, Ivana T., Ilić, Vesna Lj., Djordjević, Verica, Bukara, Katarina M., Mojsilović, Slavko B., Nedović, Viktor, Bugarski, Diana S., Veljović, Djordje, Misić, Danijela M., Bugarski, Branko, "Erythrocyte membranes from slaughterhouse blood as potential drug vehicles: Isolation by gradual hypotonic hemolysis and biochemical and morphological characterization" in Colloids and Surfaces B-Biointerfaces, 122 (2014):250-259,
https://doi.org/10.1016/j.colsurfb.2014.06.043 . .