Keskic, Tanja

Link to this page

http://aspace.agrif.bg.ac.rs/APP/faces/author.xhtml?author_id=8d0688c8-8898-4271-ab81-e1e4277fbce3&item_offset=0&project_offset=0&sort_by=dc.date.issued
Authority KeyName Variants
8d0688c8-8898-4271-ab81-e1e4277fbce3
  • Keskic, Tanja (1)
Projects
No records found.

Author's Bibliography

Second order probabilistic assessment of chronic dietary exposure to aflatoxin M1 in Serbia

Udovicki, Bozidar; Keskic, Tanja; Aleksic, Biljana; Smigic, Nada; Rajkovic, Andreja

(2023) 

TY  - JOUR
AU  - Udovicki, Bozidar
AU  - Keskic, Tanja
AU  - Aleksic, Biljana
AU  - Smigic, Nada
AU  - Rajkovic, Andreja
PY  - 2023
UR  - http://www.ncbi.nlm.nih.gov/pubmed/37343714
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6407
AB  - Considering the genotoxic and cancerogenic nature of aflatoxin M1 (AFM1), its presence in milk and dairy products may pose health risks for consumers. The chronic exposure was calculated using a two-dimensional (second order) Monte Carlo model. Results of 13 722 milk and dairy product samples analysed in the 2015-2022 period were used. Milk and dairy products intake information was collected with a Food Frequency Questionnaire (FFQ) validated by a 24-h recall-based method. Risk characterization was done by calculation of the Margin of Exposure (MOE) and by calculation of AFM1 induced number of hepatocellular carcinoma (HCC) cases. Mean AFM1 Estimated Daily Intake (EDI) was highest in children at 0.336 (CI: 0.294-0.385) ng kg-1 bw day-1, followed by adolescents with 0.183 (CI: 0.164-0.204), then adult females with 0.161 (CI: 0.146-0.179) and finally adult males with lowest EDI of 0.126 (CI: 0.115-0.139) ng kg-1 bw day-1. MOE values based on mean EDI for all population groups were above risk associated threshold and the number of possible HCC cases was in the range of 0.0002-0.0021 cases per year for 105 individuals. The results suggest low health risks due to AFM1 exposure for the whole population. Still, this risk is not non-existent, especially for children as they have a higher ratio of the population exposed to risk associated AFM1 levels, with MOE values below risk indicating threshold starting at 77.5th percentile.
T2  - Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association
T2  - Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research AssociationFood Chem Toxicol
T1  - Second order probabilistic assessment of chronic dietary exposure to aflatoxin M1 in Serbia
SP  - 113906
VL  - 178
DO  - 10.1016/j.fct.2023.113906
ER  - 
@article{
author = "Udovicki, Bozidar and Keskic, Tanja and Aleksic, Biljana and Smigic, Nada and Rajkovic, Andreja",
year = "2023",
abstract = "Considering the genotoxic and cancerogenic nature of aflatoxin M1 (AFM1), its presence in milk and dairy products may pose health risks for consumers. The chronic exposure was calculated using a two-dimensional (second order) Monte Carlo model. Results of 13 722 milk and dairy product samples analysed in the 2015-2022 period were used. Milk and dairy products intake information was collected with a Food Frequency Questionnaire (FFQ) validated by a 24-h recall-based method. Risk characterization was done by calculation of the Margin of Exposure (MOE) and by calculation of AFM1 induced number of hepatocellular carcinoma (HCC) cases. Mean AFM1 Estimated Daily Intake (EDI) was highest in children at 0.336 (CI: 0.294-0.385) ng kg-1 bw day-1, followed by adolescents with 0.183 (CI: 0.164-0.204), then adult females with 0.161 (CI: 0.146-0.179) and finally adult males with lowest EDI of 0.126 (CI: 0.115-0.139) ng kg-1 bw day-1. MOE values based on mean EDI for all population groups were above risk associated threshold and the number of possible HCC cases was in the range of 0.0002-0.0021 cases per year for 105 individuals. The results suggest low health risks due to AFM1 exposure for the whole population. Still, this risk is not non-existent, especially for children as they have a higher ratio of the population exposed to risk associated AFM1 levels, with MOE values below risk indicating threshold starting at 77.5th percentile.",
journal = "Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association, Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research AssociationFood Chem Toxicol",
title = "Second order probabilistic assessment of chronic dietary exposure to aflatoxin M1 in Serbia",
pages = "113906",
volume = "178",
doi = "10.1016/j.fct.2023.113906"
}
Udovicki, B., Keskic, T., Aleksic, B., Smigic, N.,& Rajkovic, A.. (2023). Second order probabilistic assessment of chronic dietary exposure to aflatoxin M1 in Serbia. in Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association, 178, 113906.
https://doi.org/10.1016/j.fct.2023.113906
Udovicki B, Keskic T, Aleksic B, Smigic N, Rajkovic A. Second order probabilistic assessment of chronic dietary exposure to aflatoxin M1 in Serbia. in Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association. 2023;178:113906.
doi:10.1016/j.fct.2023.113906 .
Udovicki, Bozidar, Keskic, Tanja, Aleksic, Biljana, Smigic, Nada, Rajkovic, Andreja, "Second order probabilistic assessment of chronic dietary exposure to aflatoxin M1 in Serbia" in Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association, 178 (2023):113906,
https://doi.org/10.1016/j.fct.2023.113906 . .
4