TY  - JOUR
AU  - Petrović, Danijela
AU  - Seke, Mariana
AU  - Labudović-Borović, Milica
AU  - Jović, Danica
AU  - Borisev, Ivana
AU  - Srdjenović, Branislava
AU  - Rakocević, Zlatko
AU  - Pavlović, Vladimir
AU  - Djordjević, Aleksandar
PY  - 2018
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4794
AB  - In our recent studies we have designed fullerenol/doxorubicin nanocomposite (FNP/DOX) as the new drug nanocarrier. This research has demonstrated that this novel nanocomposite has had better implications on the liver tissue in vivo (Wistar rats treated intraperitoneally), than treatment based only on DOX. FNP/DOX has been characterised by DLS, TEM and AFM measurements which have shown that DOX loaded onto FNP did not influence fullerenol nanoparticle's size. FNP/DOX affected oxidative status in blood causing a significant decrease of catalase and SOD activity in comparison to DOX, implicating the reduction in oxidative stress. qRT-PCR results on the mRNA level of antioxidative enzymes (catalase and MnSOD) revealed that the effect of oxidative stress is significantly reduced by the treatment with FNP/DOX (p lt .05). The ultrastructural analysis of the liver tissue has revealed that FNP/DOX nanocomposite generated considerably less damage in the liver tissue, than DOX applied at the same dose. Hence, our results have indicated that FNP, within FNP/DOX nanocomposite, exhibits protective effects to the liver tissue of the healthy rats.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Experimental and Molecular Pathology
T1  - Hepatoprotective effect of fullerenol/doxorubicin nanocomposite in acute treatment of healthy rats
EP  - 211
IS  - 3
SP  - 199
VL  - 104
DO  - 10.1016/j.yexmp.2018.04.005
ER  - 

@article{
author = "Petrović, Danijela and Seke, Mariana and Labudović-Borović, Milica and Jović, Danica and Borisev, Ivana and Srdjenović, Branislava and Rakocević, Zlatko and Pavlović, Vladimir and Djordjević, Aleksandar",
year = "2018",
abstract = "In our recent studies we have designed fullerenol/doxorubicin nanocomposite (FNP/DOX) as the new drug nanocarrier. This research has demonstrated that this novel nanocomposite has had better implications on the liver tissue in vivo (Wistar rats treated intraperitoneally), than treatment based only on DOX. FNP/DOX has been characterised by DLS, TEM and AFM measurements which have shown that DOX loaded onto FNP did not influence fullerenol nanoparticle's size. FNP/DOX affected oxidative status in blood causing a significant decrease of catalase and SOD activity in comparison to DOX, implicating the reduction in oxidative stress. qRT-PCR results on the mRNA level of antioxidative enzymes (catalase and MnSOD) revealed that the effect of oxidative stress is significantly reduced by the treatment with FNP/DOX (p lt .05). The ultrastructural analysis of the liver tissue has revealed that FNP/DOX nanocomposite generated considerably less damage in the liver tissue, than DOX applied at the same dose. Hence, our results have indicated that FNP, within FNP/DOX nanocomposite, exhibits protective effects to the liver tissue of the healthy rats.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Experimental and Molecular Pathology",
title = "Hepatoprotective effect of fullerenol/doxorubicin nanocomposite in acute treatment of healthy rats",
pages = "211-199",
number = "3",
volume = "104",
doi = "10.1016/j.yexmp.2018.04.005"
}

Petrović, D., Seke, M., Labudović-Borović, M., Jović, D., Borisev, I., Srdjenović, B., Rakocević, Z., Pavlović, V.,& Djordjević, A.. (2018). Hepatoprotective effect of fullerenol/doxorubicin nanocomposite in acute treatment of healthy rats. in Experimental and Molecular Pathology
Academic Press Inc Elsevier Science, San Diego., 104(3), 199-211.
https://doi.org/10.1016/j.yexmp.2018.04.005

Petrović D, Seke M, Labudović-Borović M, Jović D, Borisev I, Srdjenović B, Rakocević Z, Pavlović V, Djordjević A. Hepatoprotective effect of fullerenol/doxorubicin nanocomposite in acute treatment of healthy rats. in Experimental and Molecular Pathology. 2018;104(3):199-211.
doi:10.1016/j.yexmp.2018.04.005 .

Petrović, Danijela, Seke, Mariana, Labudović-Borović, Milica, Jović, Danica, Borisev, Ivana, Srdjenović, Branislava, Rakocević, Zlatko, Pavlović, Vladimir, Djordjević, Aleksandar, "Hepatoprotective effect of fullerenol/doxorubicin nanocomposite in acute treatment of healthy rats" in Experimental and Molecular Pathology, 104, no. 3 (2018):199-211,
https://doi.org/10.1016/j.yexmp.2018.04.005 . .

TY  - JOUR
AU  - Jaksić, Zoran
AU  - Pantelić, Dejan
AU  - Sarajlić, Milija
AU  - Savić-Sević, Svetlana
AU  - Matović, Jovan
AU  - Jelenković, Branislav
AU  - Vasiljević-Radović, Dana
AU  - Curcić, Srecko
AU  - Vuković, Slobodan
AU  - Pavlović, Vladimir
AU  - Buha, Jelena
AU  - Lacković, Vesna
AU  - Labudović-Borović, Milica
AU  - Curcić, Bozidar
PY  - 2013
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3322
AB  - In this paper we propose a possible use of butterfly scales as templates for ordered 2D or 3D nanophotonic materials, with complexity not easily reproducible by conventional micro/nanofabrication methods. Functionalization through laminar nanocompositing is utilized to impart novel properties to the biological scaffold. An extremely wide variability of butterfly scale forms, shapes, sizes and fine structures is observed in nature, many of them already possessing peculiar optical properties. Their nanophotonic functionalization ensures a large choice of forms and functions, including enhanced light localization, light and plasmon waveguiding and general metamaterial behavior, to mention a few. We show that one is able to achieve a combination of plasmonics and bionics, resulting in functionalities seldom if ever met in nature. As an illustration we have analyzed the photonic properties of the nanostructured scales on the wings of Purple Emperor butterflies Apatura ilia, Apatura iris and Sasakia charonda. Their intricate nanometer-sized structures produce remarkable ultraviolet-blue iridescence, spectrally and directionally narrow. We present our analysis of their plasmonic/nanophotonic functionalization including preliminary calculations and initial experimental results. As a simple example, we used radiofrequent sputtering to produce nanoaperture-based plasmonic structures at a fraction of the cost and necessary engineering efforts compared to the conventional top-down methods. We conclude that the described pathway to biomimetic plasmonics offers potentials for significant expansion of the nanophotonic and nanoplasmonic material toolbox.
PB  - Elsevier Science Bv, Amsterdam
T2  - Optical Materials
T1  - Butterfly scales as bionic templates for complex ordered nanophotonic materials: A pathway to biomimetic plasmonics
EP  - 1875
IS  - 10
SP  - 1869
VL  - 35
DO  - 10.1016/j.optmat.2013.04.004
ER  - 

@article{
author = "Jaksić, Zoran and Pantelić, Dejan and Sarajlić, Milija and Savić-Sević, Svetlana and Matović, Jovan and Jelenković, Branislav and Vasiljević-Radović, Dana and Curcić, Srecko and Vuković, Slobodan and Pavlović, Vladimir and Buha, Jelena and Lacković, Vesna and Labudović-Borović, Milica and Curcić, Bozidar",
year = "2013",
abstract = "In this paper we propose a possible use of butterfly scales as templates for ordered 2D or 3D nanophotonic materials, with complexity not easily reproducible by conventional micro/nanofabrication methods. Functionalization through laminar nanocompositing is utilized to impart novel properties to the biological scaffold. An extremely wide variability of butterfly scale forms, shapes, sizes and fine structures is observed in nature, many of them already possessing peculiar optical properties. Their nanophotonic functionalization ensures a large choice of forms and functions, including enhanced light localization, light and plasmon waveguiding and general metamaterial behavior, to mention a few. We show that one is able to achieve a combination of plasmonics and bionics, resulting in functionalities seldom if ever met in nature. As an illustration we have analyzed the photonic properties of the nanostructured scales on the wings of Purple Emperor butterflies Apatura ilia, Apatura iris and Sasakia charonda. Their intricate nanometer-sized structures produce remarkable ultraviolet-blue iridescence, spectrally and directionally narrow. We present our analysis of their plasmonic/nanophotonic functionalization including preliminary calculations and initial experimental results. As a simple example, we used radiofrequent sputtering to produce nanoaperture-based plasmonic structures at a fraction of the cost and necessary engineering efforts compared to the conventional top-down methods. We conclude that the described pathway to biomimetic plasmonics offers potentials for significant expansion of the nanophotonic and nanoplasmonic material toolbox.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Optical Materials",
title = "Butterfly scales as bionic templates for complex ordered nanophotonic materials: A pathway to biomimetic plasmonics",
pages = "1875-1869",
number = "10",
volume = "35",
doi = "10.1016/j.optmat.2013.04.004"
}

Jaksić, Z., Pantelić, D., Sarajlić, M., Savić-Sević, S., Matović, J., Jelenković, B., Vasiljević-Radović, D., Curcić, S., Vuković, S., Pavlović, V., Buha, J., Lacković, V., Labudović-Borović, M.,& Curcić, B.. (2013). Butterfly scales as bionic templates for complex ordered nanophotonic materials: A pathway to biomimetic plasmonics. in Optical Materials
Elsevier Science Bv, Amsterdam., 35(10), 1869-1875.
https://doi.org/10.1016/j.optmat.2013.04.004

Jaksić Z, Pantelić D, Sarajlić M, Savić-Sević S, Matović J, Jelenković B, Vasiljević-Radović D, Curcić S, Vuković S, Pavlović V, Buha J, Lacković V, Labudović-Borović M, Curcić B. Butterfly scales as bionic templates for complex ordered nanophotonic materials: A pathway to biomimetic plasmonics. in Optical Materials. 2013;35(10):1869-1875.
doi:10.1016/j.optmat.2013.04.004 .

Jaksić, Zoran, Pantelić, Dejan, Sarajlić, Milija, Savić-Sević, Svetlana, Matović, Jovan, Jelenković, Branislav, Vasiljević-Radović, Dana, Curcić, Srecko, Vuković, Slobodan, Pavlović, Vladimir, Buha, Jelena, Lacković, Vesna, Labudović-Borović, Milica, Curcić, Bozidar, "Butterfly scales as bionic templates for complex ordered nanophotonic materials: A pathway to biomimetic plasmonics" in Optical Materials, 35, no. 10 (2013):1869-1875,
https://doi.org/10.1016/j.optmat.2013.04.004 . .