TY  - JOUR
AU  - Petrović, Danijela
AU  - Seke, Mariana
AU  - Labudović-Borović, Milica
AU  - Jović, Danica
AU  - Borisev, Ivana
AU  - Srdjenović, Branislava
AU  - Rakocević, Zlatko
AU  - Pavlović, Vladimir
AU  - Djordjević, Aleksandar
PY  - 2018
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4794
AB  - In our recent studies we have designed fullerenol/doxorubicin nanocomposite (FNP/DOX) as the new drug nanocarrier. This research has demonstrated that this novel nanocomposite has had better implications on the liver tissue in vivo (Wistar rats treated intraperitoneally), than treatment based only on DOX. FNP/DOX has been characterised by DLS, TEM and AFM measurements which have shown that DOX loaded onto FNP did not influence fullerenol nanoparticle's size. FNP/DOX affected oxidative status in blood causing a significant decrease of catalase and SOD activity in comparison to DOX, implicating the reduction in oxidative stress. qRT-PCR results on the mRNA level of antioxidative enzymes (catalase and MnSOD) revealed that the effect of oxidative stress is significantly reduced by the treatment with FNP/DOX (p lt .05). The ultrastructural analysis of the liver tissue has revealed that FNP/DOX nanocomposite generated considerably less damage in the liver tissue, than DOX applied at the same dose. Hence, our results have indicated that FNP, within FNP/DOX nanocomposite, exhibits protective effects to the liver tissue of the healthy rats.
PB  - Academic Press Inc Elsevier Science, San Diego
T2  - Experimental and Molecular Pathology
T1  - Hepatoprotective effect of fullerenol/doxorubicin nanocomposite in acute treatment of healthy rats
EP  - 211
IS  - 3
SP  - 199
VL  - 104
DO  - 10.1016/j.yexmp.2018.04.005
ER  - 

@article{
author = "Petrović, Danijela and Seke, Mariana and Labudović-Borović, Milica and Jović, Danica and Borisev, Ivana and Srdjenović, Branislava and Rakocević, Zlatko and Pavlović, Vladimir and Djordjević, Aleksandar",
year = "2018",
abstract = "In our recent studies we have designed fullerenol/doxorubicin nanocomposite (FNP/DOX) as the new drug nanocarrier. This research has demonstrated that this novel nanocomposite has had better implications on the liver tissue in vivo (Wistar rats treated intraperitoneally), than treatment based only on DOX. FNP/DOX has been characterised by DLS, TEM and AFM measurements which have shown that DOX loaded onto FNP did not influence fullerenol nanoparticle's size. FNP/DOX affected oxidative status in blood causing a significant decrease of catalase and SOD activity in comparison to DOX, implicating the reduction in oxidative stress. qRT-PCR results on the mRNA level of antioxidative enzymes (catalase and MnSOD) revealed that the effect of oxidative stress is significantly reduced by the treatment with FNP/DOX (p lt .05). The ultrastructural analysis of the liver tissue has revealed that FNP/DOX nanocomposite generated considerably less damage in the liver tissue, than DOX applied at the same dose. Hence, our results have indicated that FNP, within FNP/DOX nanocomposite, exhibits protective effects to the liver tissue of the healthy rats.",
publisher = "Academic Press Inc Elsevier Science, San Diego",
journal = "Experimental and Molecular Pathology",
title = "Hepatoprotective effect of fullerenol/doxorubicin nanocomposite in acute treatment of healthy rats",
pages = "211-199",
number = "3",
volume = "104",
doi = "10.1016/j.yexmp.2018.04.005"
}

Petrović, D., Seke, M., Labudović-Borović, M., Jović, D., Borisev, I., Srdjenović, B., Rakocević, Z., Pavlović, V.,& Djordjević, A.. (2018). Hepatoprotective effect of fullerenol/doxorubicin nanocomposite in acute treatment of healthy rats. in Experimental and Molecular Pathology
Academic Press Inc Elsevier Science, San Diego., 104(3), 199-211.
https://doi.org/10.1016/j.yexmp.2018.04.005

Petrović D, Seke M, Labudović-Borović M, Jović D, Borisev I, Srdjenović B, Rakocević Z, Pavlović V, Djordjević A. Hepatoprotective effect of fullerenol/doxorubicin nanocomposite in acute treatment of healthy rats. in Experimental and Molecular Pathology. 2018;104(3):199-211.
doi:10.1016/j.yexmp.2018.04.005 .

Petrović, Danijela, Seke, Mariana, Labudović-Borović, Milica, Jović, Danica, Borisev, Ivana, Srdjenović, Branislava, Rakocević, Zlatko, Pavlović, Vladimir, Djordjević, Aleksandar, "Hepatoprotective effect of fullerenol/doxorubicin nanocomposite in acute treatment of healthy rats" in Experimental and Molecular Pathology, 104, no. 3 (2018):199-211,
https://doi.org/10.1016/j.yexmp.2018.04.005 . .

TY  - JOUR
AU  - Momić, Tatjana
AU  - Lazarević-Pasti, Tamara
AU  - Bogdanović, Una
AU  - Vodnik, Vesna
AU  - Mraković, Ana
AU  - Rakocević, Zlatko
AU  - Pavlović, Vladimir
AU  - Vasić, Vesna
PY  - 2016
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4038
AB  - Organophosphorus pesticide dimethoate was adsorbed onto gold nanospheres and nanorods in aqueous solution using batch technique. Adsorption of dimethoate onto gold nanoparticles was confirmed by UV-Vis spectrophotometry, TEM, AFM, and FTIR analysis. The adsorption of nanospheres resulted in aggregation which was not the case with nanorods. Nanoparticles adsorption features were characterized using Langmuir and Freundlich isotherm models. The Langmuir adsorption isotherm was found to have the best fit to the experimental data for both types of nanoparticles. Adsorption capacity detected for nanospheres is 456 mg/g and for nanorods is 57.1 mg/g. Also, nanoparticles were successfully used for dimethoate removal from spiked drinking water while nanospheres were shown to be more efficient than nanorods.
PB  - Hindawi Ltd, London
T2  - Journal of Nanomaterials
T1  - Adsorption of Organophosphate Pesticide Dimethoate on Gold Nanospheres and Nanorods
VL  - 2016
DO  - 10.1155/2016/8910271
ER  - 

@article{
author = "Momić, Tatjana and Lazarević-Pasti, Tamara and Bogdanović, Una and Vodnik, Vesna and Mraković, Ana and Rakocević, Zlatko and Pavlović, Vladimir and Vasić, Vesna",
year = "2016",
abstract = "Organophosphorus pesticide dimethoate was adsorbed onto gold nanospheres and nanorods in aqueous solution using batch technique. Adsorption of dimethoate onto gold nanoparticles was confirmed by UV-Vis spectrophotometry, TEM, AFM, and FTIR analysis. The adsorption of nanospheres resulted in aggregation which was not the case with nanorods. Nanoparticles adsorption features were characterized using Langmuir and Freundlich isotherm models. The Langmuir adsorption isotherm was found to have the best fit to the experimental data for both types of nanoparticles. Adsorption capacity detected for nanospheres is 456 mg/g and for nanorods is 57.1 mg/g. Also, nanoparticles were successfully used for dimethoate removal from spiked drinking water while nanospheres were shown to be more efficient than nanorods.",
publisher = "Hindawi Ltd, London",
journal = "Journal of Nanomaterials",
title = "Adsorption of Organophosphate Pesticide Dimethoate on Gold Nanospheres and Nanorods",
volume = "2016",
doi = "10.1155/2016/8910271"
}

Momić, T., Lazarević-Pasti, T., Bogdanović, U., Vodnik, V., Mraković, A., Rakocević, Z., Pavlović, V.,& Vasić, V.. (2016). Adsorption of Organophosphate Pesticide Dimethoate on Gold Nanospheres and Nanorods. in Journal of Nanomaterials
Hindawi Ltd, London., 2016.
https://doi.org/10.1155/2016/8910271

Momić T, Lazarević-Pasti T, Bogdanović U, Vodnik V, Mraković A, Rakocević Z, Pavlović V, Vasić V. Adsorption of Organophosphate Pesticide Dimethoate on Gold Nanospheres and Nanorods. in Journal of Nanomaterials. 2016;2016.
doi:10.1155/2016/8910271 .

Momić, Tatjana, Lazarević-Pasti, Tamara, Bogdanović, Una, Vodnik, Vesna, Mraković, Ana, Rakocević, Zlatko, Pavlović, Vladimir, Vasić, Vesna, "Adsorption of Organophosphate Pesticide Dimethoate on Gold Nanospheres and Nanorods" in Journal of Nanomaterials, 2016 (2016),
https://doi.org/10.1155/2016/8910271 . .