TY  - JOUR
AU  - Popović-Djordjević, Jelena
AU  - Kostić, Aleksandar Ž.
AU  - Kamiloglu, Senem
AU  - Tomas, Merve
AU  - Mićanović, Nenad
AU  - Capanoglu, Esra
PY  - 2023
UR  - https://doi.org/10.1007/s11101-023-09883-y
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6396
AB  - The common medlar (Mespilus germanica L.) is one of two species within the Mespilus genus (Maloideae subfamily). Its use can be traced back almost 30 centuries, from ancient Assyrians and Babylonians to Greeks and Romans and through modern times. During the Middle Ages it was a popular fruit tree and a highly appreciated ornamental tree in gardens across Europe. However, in modern times, the medlar is often considered an underestimated and underutilized fruit from the Rosaceae family. Nevertheless, it is slowly regaining its ‘medieval glory’ and commercial importance as a food-stuff for human consumption. The medlar plant has a wide array of traditional uses in both gastronomy and medicine. Ripe medlar fruits can be consumed fresh or processed into different products such as juice, concentrate, jam, cheese, leather, and honey. Meanwhile, unripe fruits can be used to prepare pickles or beverages such as cider. The nutritional potential of medlar fruits is attributed to sugars, organic acids, fatty acids, carotenoids, amino acids and proteins, vitamins, and essential elements. Scarce literature describes the richness of medlar fruit in bioactive phenolic compounds such as flavonoids and phenolic acids, which contribute to its antioxidant and antidiabetic properties. Additionally, a few studies describe other biological properties of the medlar plant including antimicrobial, cytotoxic and neurodegenerative effects of medlar fruits and leaves, while reports on the clinical studies are lacking. This review paper summarizes the chemical and nutritional properties of medlar fruit, traditional medicinal uses and biological activity of the medlar plant, relying on the most relevant and up to date scientific literature in the field.
T2  - Phytochemistry Reviews
T2  - Phytochemistry ReviewsPhytochem Rev
T1  - Chemical composition, nutritional and health related properties of the medlar (Mespilus germanica L.): from medieval glory to underutilized fruit
DO  - 10.1007/s11101-023-09883-y
ER  - 

@article{
author = "Popović-Djordjević, Jelena and Kostić, Aleksandar Ž. and Kamiloglu, Senem and Tomas, Merve and Mićanović, Nenad and Capanoglu, Esra",
year = "2023",
abstract = "The common medlar (Mespilus germanica L.) is one of two species within the Mespilus genus (Maloideae subfamily). Its use can be traced back almost 30 centuries, from ancient Assyrians and Babylonians to Greeks and Romans and through modern times. During the Middle Ages it was a popular fruit tree and a highly appreciated ornamental tree in gardens across Europe. However, in modern times, the medlar is often considered an underestimated and underutilized fruit from the Rosaceae family. Nevertheless, it is slowly regaining its ‘medieval glory’ and commercial importance as a food-stuff for human consumption. The medlar plant has a wide array of traditional uses in both gastronomy and medicine. Ripe medlar fruits can be consumed fresh or processed into different products such as juice, concentrate, jam, cheese, leather, and honey. Meanwhile, unripe fruits can be used to prepare pickles or beverages such as cider. The nutritional potential of medlar fruits is attributed to sugars, organic acids, fatty acids, carotenoids, amino acids and proteins, vitamins, and essential elements. Scarce literature describes the richness of medlar fruit in bioactive phenolic compounds such as flavonoids and phenolic acids, which contribute to its antioxidant and antidiabetic properties. Additionally, a few studies describe other biological properties of the medlar plant including antimicrobial, cytotoxic and neurodegenerative effects of medlar fruits and leaves, while reports on the clinical studies are lacking. This review paper summarizes the chemical and nutritional properties of medlar fruit, traditional medicinal uses and biological activity of the medlar plant, relying on the most relevant and up to date scientific literature in the field.",
journal = "Phytochemistry Reviews, Phytochemistry ReviewsPhytochem Rev",
title = "Chemical composition, nutritional and health related properties of the medlar (Mespilus germanica L.): from medieval glory to underutilized fruit",
doi = "10.1007/s11101-023-09883-y"
}

Popović-Djordjević, J., Kostić, A. Ž., Kamiloglu, S., Tomas, M., Mićanović, N.,& Capanoglu, E.. (2023). Chemical composition, nutritional and health related properties of the medlar (Mespilus germanica L.): from medieval glory to underutilized fruit. in Phytochemistry Reviews.
https://doi.org/10.1007/s11101-023-09883-y

Popović-Djordjević J, Kostić AŽ, Kamiloglu S, Tomas M, Mićanović N, Capanoglu E. Chemical composition, nutritional and health related properties of the medlar (Mespilus germanica L.): from medieval glory to underutilized fruit. in Phytochemistry Reviews. 2023;.
doi:10.1007/s11101-023-09883-y .

Popović-Djordjević, Jelena, Kostić, Aleksandar Ž., Kamiloglu, Senem, Tomas, Merve, Mićanović, Nenad, Capanoglu, Esra, "Chemical composition, nutritional and health related properties of the medlar (Mespilus germanica L.): from medieval glory to underutilized fruit" in Phytochemistry Reviews (2023),
https://doi.org/10.1007/s11101-023-09883-y . .

TY  - JOUR
AU  - Sharifi-Rad, Javad
AU  - Kobarfard, Farzad
AU  - Ata, Athar
AU  - Ayatollahi, Seyed Abdulmajid
AU  - Khosravi-Dehaghi, Nafiseh
AU  - Jugran, Arun Kumar
AU  - Tomas, Merve
AU  - Capanoglu, Esra
AU  - Matthews, Karl R.
AU  - Popović-Djordjević, Jelena
AU  - Kostić, Aleksandar
AU  - Kamiloglu, Senem
AU  - Sharopov, Farukh
AU  - Choudhary, Muhammad Iqbal
AU  - Martins, Natalia
PY  - 2019
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4978
AB  - Members of the Prosopis genus are native to America, Africa and Asia, and have long been used in traditional medicine. The Prosopis species most commonly used for medicinal purposes are P. africana, P. alba, P. cineraria, P. farcta, P. glandulosa, P. juliflora, P. nigra, P. ruscifolia and P. spicigera, which are highly effective in asthma, birth/postpartum pains, callouses, conjunctivitis, diabetes, diarrhea, expectorant, fever, flu, lactation, liver infection, malaria, otitis, pains, pediculosis, rheumatism, scabies, skin inflammations, spasm, stomach ache, bladder and pancreas stone removal. Flour, syrup, and beverages from Prosopis pods have also been potentially used for foods and food supplement formulation in many regions of the world. In addition, various in vitro and in vivo studies have revealed interesting antiplasmodial, antipyretic, anti-inflammatory, antimicrobial, anticancer, antidiabetic and wound healing effects. The phytochemical composition of Prosopis plants, namely their content of C-glycosyl flavones (such as schaftoside, isoschaftoside, vicenin II, vitexin and isovitexin) has been increasingly correlated with the observed biological effects. Thus, given the literature reports, Prosopis plants have positive impact on the human diet and general health. In this sense, the present review provides an in-depth overview of the literature data regarding Prosopis plants' chemical composition, pharmacological and food applications, covering from pre-clinical data to upcoming clinical studies.
PB  - MDPI, BASEL
T2  - Biomolecules
T1  - Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence
IS  - 12
VL  - 9
DO  - 10.3390/biom9120777
ER  - 

@article{
author = "Sharifi-Rad, Javad and Kobarfard, Farzad and Ata, Athar and Ayatollahi, Seyed Abdulmajid and Khosravi-Dehaghi, Nafiseh and Jugran, Arun Kumar and Tomas, Merve and Capanoglu, Esra and Matthews, Karl R. and Popović-Djordjević, Jelena and Kostić, Aleksandar and Kamiloglu, Senem and Sharopov, Farukh and Choudhary, Muhammad Iqbal and Martins, Natalia",
year = "2019",
abstract = "Members of the Prosopis genus are native to America, Africa and Asia, and have long been used in traditional medicine. The Prosopis species most commonly used for medicinal purposes are P. africana, P. alba, P. cineraria, P. farcta, P. glandulosa, P. juliflora, P. nigra, P. ruscifolia and P. spicigera, which are highly effective in asthma, birth/postpartum pains, callouses, conjunctivitis, diabetes, diarrhea, expectorant, fever, flu, lactation, liver infection, malaria, otitis, pains, pediculosis, rheumatism, scabies, skin inflammations, spasm, stomach ache, bladder and pancreas stone removal. Flour, syrup, and beverages from Prosopis pods have also been potentially used for foods and food supplement formulation in many regions of the world. In addition, various in vitro and in vivo studies have revealed interesting antiplasmodial, antipyretic, anti-inflammatory, antimicrobial, anticancer, antidiabetic and wound healing effects. The phytochemical composition of Prosopis plants, namely their content of C-glycosyl flavones (such as schaftoside, isoschaftoside, vicenin II, vitexin and isovitexin) has been increasingly correlated with the observed biological effects. Thus, given the literature reports, Prosopis plants have positive impact on the human diet and general health. In this sense, the present review provides an in-depth overview of the literature data regarding Prosopis plants' chemical composition, pharmacological and food applications, covering from pre-clinical data to upcoming clinical studies.",
publisher = "MDPI, BASEL",
journal = "Biomolecules",
title = "Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence",
number = "12",
volume = "9",
doi = "10.3390/biom9120777"
}

Sharifi-Rad, J., Kobarfard, F., Ata, A., Ayatollahi, S. A., Khosravi-Dehaghi, N., Jugran, A. K., Tomas, M., Capanoglu, E., Matthews, K. R., Popović-Djordjević, J., Kostić, A., Kamiloglu, S., Sharopov, F., Choudhary, M. I.,& Martins, N.. (2019). Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence. in Biomolecules
MDPI, BASEL., 9(12).
https://doi.org/10.3390/biom9120777

Sharifi-Rad J, Kobarfard F, Ata A, Ayatollahi SA, Khosravi-Dehaghi N, Jugran AK, Tomas M, Capanoglu E, Matthews KR, Popović-Djordjević J, Kostić A, Kamiloglu S, Sharopov F, Choudhary MI, Martins N. Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence. in Biomolecules. 2019;9(12).
doi:10.3390/biom9120777 .

Sharifi-Rad, Javad, Kobarfard, Farzad, Ata, Athar, Ayatollahi, Seyed Abdulmajid, Khosravi-Dehaghi, Nafiseh, Jugran, Arun Kumar, Tomas, Merve, Capanoglu, Esra, Matthews, Karl R., Popović-Djordjević, Jelena, Kostić, Aleksandar, Kamiloglu, Senem, Sharopov, Farukh, Choudhary, Muhammad Iqbal, Martins, Natalia, "Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence" in Biomolecules, 9, no. 12 (2019),
https://doi.org/10.3390/biom9120777 . .