TY  - JOUR
AU  - Glavinić, Uroš
AU  - Stevanović, Jevrosima
AU  - Ristanić, Marko
AU  - Rajković, Milan
AU  - Davitkov, Dajana
AU  - Lakić, Nada
AU  - Stanimirović, Zoran
PY  - 2021
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/5832
AB  - Depending on the infection level and colony strength, Nosema ceranae, a microsporidian endoparasite of the honey bee may have significant consequences on the health, reproduction and productivity of bee colonies. Despite exerting some side effects, fumagillin is most often used for Nosema control. In this study, in a cage experiment, N. ceranae infected bees were treated with fumagillin or the extract of Agaricus blazei mushroom, a possible alternative for Nosema control. Bee survival, Nosema spore loads, the expression levels of immune-related genes and parameters of oxidative stress were observed. Fumagillin treatment showed a negative effect on monitored parameters when applied preventively to non-infected bees, while a noticeable anti-Nosema effect and protection from Nosema-induced immunosuppression and oxidative stress were proven in Nosema-infected bees. However, a protective effect of the natural A. blazei extract was detected, without any side effects but with immunostimulatory activity in the preventive application. The results of this research suggest the potential of A. blazei extract for Nosema control, which needs to be further investigated.
PB  - MDPI AG
T2  - Insects
T1  - Potential of Fumagillin and Agaricus blazei Mushroom Extract to Reduce Nosema ceranae in Honey Bees
IS  - 4
SP  - 282
VL  - 12
DO  - 10.3390/insects12040282
ER  - 

@article{
author = "Glavinić, Uroš and Stevanović, Jevrosima and Ristanić, Marko and Rajković, Milan and Davitkov, Dajana and Lakić, Nada and Stanimirović, Zoran",
year = "2021",
abstract = "Depending on the infection level and colony strength, Nosema ceranae, a microsporidian endoparasite of the honey bee may have significant consequences on the health, reproduction and productivity of bee colonies. Despite exerting some side effects, fumagillin is most often used for Nosema control. In this study, in a cage experiment, N. ceranae infected bees were treated with fumagillin or the extract of Agaricus blazei mushroom, a possible alternative for Nosema control. Bee survival, Nosema spore loads, the expression levels of immune-related genes and parameters of oxidative stress were observed. Fumagillin treatment showed a negative effect on monitored parameters when applied preventively to non-infected bees, while a noticeable anti-Nosema effect and protection from Nosema-induced immunosuppression and oxidative stress were proven in Nosema-infected bees. However, a protective effect of the natural A. blazei extract was detected, without any side effects but with immunostimulatory activity in the preventive application. The results of this research suggest the potential of A. blazei extract for Nosema control, which needs to be further investigated.",
publisher = "MDPI AG",
journal = "Insects",
title = "Potential of Fumagillin and Agaricus blazei Mushroom Extract to Reduce Nosema ceranae in Honey Bees",
number = "4",
pages = "282",
volume = "12",
doi = "10.3390/insects12040282"
}

Glavinić, U., Stevanović, J., Ristanić, M., Rajković, M., Davitkov, D., Lakić, N.,& Stanimirović, Z.. (2021). Potential of Fumagillin and Agaricus blazei Mushroom Extract to Reduce Nosema ceranae in Honey Bees. in Insects
MDPI AG., 12(4), 282.
https://doi.org/10.3390/insects12040282

Glavinić U, Stevanović J, Ristanić M, Rajković M, Davitkov D, Lakić N, Stanimirović Z. Potential of Fumagillin and Agaricus blazei Mushroom Extract to Reduce Nosema ceranae in Honey Bees. in Insects. 2021;12(4):282.
doi:10.3390/insects12040282 .

Glavinić, Uroš, Stevanović, Jevrosima, Ristanić, Marko, Rajković, Milan, Davitkov, Dajana, Lakić, Nada, Stanimirović, Zoran, "Potential of Fumagillin and Agaricus blazei Mushroom Extract to Reduce Nosema ceranae in Honey Bees" in Insects, 12, no. 4 (2021):282,
https://doi.org/10.3390/insects12040282 . .