TY  - JOUR
AU  - Božić, Aleksandra R.
AU  - Filipović, Nenad
AU  - Novaković, Irena
AU  - Bjelogrlić, Snežana
AU  - Nikolić, Jasmina B.
AU  - Drmanić, Sasa Z.
AU  - Marinković, Aleksandar D.
PY  - 2017
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4456
AB  - Fourteen mono- and bis-carbohydrazone ligands have been synthesized and characterized. Antioxidant activity of the substances was investigated together with possible (E)/(Z) isomerization, and explained on the most active antioxidant compound 4 in various dimethyl sulphoxide-water mixtures. The addition of water to the system was involved in the formation of hydrated molecules which was confirmed in NMR after the addition of D2O. The ligands were tested in vitro against Gram-positive and Gram-negative bacteria and fungi, and their activity was discussed in relation to the structure of investigated carbohydrazone.
PB  - Srpsko hemijsko društvo, Beograd
T2  - JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
T1  - Synthesis, antioxidant and antimicrobial activity of carbohydrazones
EP  - 508
IS  - 5
SP  - 495
VL  - 82
DO  - 10.2298/JSC161220045B
ER  - 

@article{
author = "Božić, Aleksandra R. and Filipović, Nenad and Novaković, Irena and Bjelogrlić, Snežana and Nikolić, Jasmina B. and Drmanić, Sasa Z. and Marinković, Aleksandar D.",
year = "2017",
abstract = "Fourteen mono- and bis-carbohydrazone ligands have been synthesized and characterized. Antioxidant activity of the substances was investigated together with possible (E)/(Z) isomerization, and explained on the most active antioxidant compound 4 in various dimethyl sulphoxide-water mixtures. The addition of water to the system was involved in the formation of hydrated molecules which was confirmed in NMR after the addition of D2O. The ligands were tested in vitro against Gram-positive and Gram-negative bacteria and fungi, and their activity was discussed in relation to the structure of investigated carbohydrazone.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "JOURNAL OF THE SERBIAN CHEMICAL SOCIETY",
title = "Synthesis, antioxidant and antimicrobial activity of carbohydrazones",
pages = "508-495",
number = "5",
volume = "82",
doi = "10.2298/JSC161220045B"
}

Božić, A. R., Filipović, N., Novaković, I., Bjelogrlić, S., Nikolić, J. B., Drmanić, S. Z.,& Marinković, A. D.. (2017). Synthesis, antioxidant and antimicrobial activity of carbohydrazones. in JOURNAL OF THE SERBIAN CHEMICAL SOCIETY
Srpsko hemijsko društvo, Beograd., 82(5), 495-508.
https://doi.org/10.2298/JSC161220045B

Božić AR, Filipović N, Novaković I, Bjelogrlić S, Nikolić JB, Drmanić SZ, Marinković AD. Synthesis, antioxidant and antimicrobial activity of carbohydrazones. in JOURNAL OF THE SERBIAN CHEMICAL SOCIETY. 2017;82(5):495-508.
doi:10.2298/JSC161220045B .

Božić, Aleksandra R., Filipović, Nenad, Novaković, Irena, Bjelogrlić, Snežana, Nikolić, Jasmina B., Drmanić, Sasa Z., Marinković, Aleksandar D., "Synthesis, antioxidant and antimicrobial activity of carbohydrazones" in JOURNAL OF THE SERBIAN CHEMICAL SOCIETY, 82, no. 5 (2017):495-508,
https://doi.org/10.2298/JSC161220045B . .

TY  - JOUR
AU  - Tasić, Ana
AU  - Rusmirović, Jelena D.
AU  - Nikolić, Jovana
AU  - Božić, Aleksandra
AU  - Pavlović, Vladimir
AU  - Marinković, Aleksandar D.
AU  - Uskoković, Petar S.
PY  - 2017
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4381
AB  - Production of high-performance nanocomposite materials obtained from unsaturated polyester resin, based on products of the waste poly(ethylene terephthalate) recycling, and modified multi-walled carbon nanotubes is presented. Di-hydroxy functional glycolysates, synthesized by catalytic depolymerization of poly(ethylene terephthalate) with propylene glycol, were used for the unsaturated polyester resin synthesis. The structure of the obtained glycolysis product and unsaturated polyester resin were characterized by using FTIR and NMR spectroscopy, and by acid, iodine, and hydroxyl value. Nanofillers were prepared by direct and two-step amidation of oxidized multi-walled carbon nanotubes. Direct amidation with diallylamine produced multi-walled carbon nanotube-diallylamine reactive nanofiller. Two-step modification with diamines: hexamethylenediamine and p-phenylenediamine gave multi-walled carbon nanotubehexamethylenediamine and multi-walled carbon nanotube-p-phenylenediamine nanofiller, respectively, whose amidation with methyl ester of linseed oil fatty acids gave multi-walled carbon nanotube-hexamethylenediamine/methyl ester of linseed oil fatty acid and multi-walled carbon nanotube-p-phenylenediamine/methyl ester of linseed oil fatty acid nanofiller, respectively. Influences of vinyl functionalities on mechanical properties of nanocomposite were analyzed from tensile strength (sigma(b)), elongation (epsilon(b)) and Young's modulus (E) determination. An increase of 97.4, 119 and 139% of sigma(b) was obtained for nanocomposites with addition of 0.25 wt.% of diallylamine, p-phenylenediamine/methyl ester of linseed oil fatty acid and hexamethylenediamine/methyl ester of linseed oil fatty acid multi-walled carbon nanotubes, respectively. Short techno-economic analysis, performed on the basis of fixed and variable unsaturated polyester resin production costs, showed satisfactory potential profit, which could be realized by the implementation of the presented technology.
PB  - Sage Publications Ltd, London
T2  - Journal of Composite Materials
T1  - Effect of the vinyl modification of multi-walled carbon nanotubes on the performances of waste poly(ethylene terephthalate)-based nanocomposites
EP  - 505
IS  - 4
SP  - 491
VL  - 51
DO  - 10.1177/0021998316648757
ER  - 

@article{
author = "Tasić, Ana and Rusmirović, Jelena D. and Nikolić, Jovana and Božić, Aleksandra and Pavlović, Vladimir and Marinković, Aleksandar D. and Uskoković, Petar S.",
year = "2017",
abstract = "Production of high-performance nanocomposite materials obtained from unsaturated polyester resin, based on products of the waste poly(ethylene terephthalate) recycling, and modified multi-walled carbon nanotubes is presented. Di-hydroxy functional glycolysates, synthesized by catalytic depolymerization of poly(ethylene terephthalate) with propylene glycol, were used for the unsaturated polyester resin synthesis. The structure of the obtained glycolysis product and unsaturated polyester resin were characterized by using FTIR and NMR spectroscopy, and by acid, iodine, and hydroxyl value. Nanofillers were prepared by direct and two-step amidation of oxidized multi-walled carbon nanotubes. Direct amidation with diallylamine produced multi-walled carbon nanotube-diallylamine reactive nanofiller. Two-step modification with diamines: hexamethylenediamine and p-phenylenediamine gave multi-walled carbon nanotubehexamethylenediamine and multi-walled carbon nanotube-p-phenylenediamine nanofiller, respectively, whose amidation with methyl ester of linseed oil fatty acids gave multi-walled carbon nanotube-hexamethylenediamine/methyl ester of linseed oil fatty acid and multi-walled carbon nanotube-p-phenylenediamine/methyl ester of linseed oil fatty acid nanofiller, respectively. Influences of vinyl functionalities on mechanical properties of nanocomposite were analyzed from tensile strength (sigma(b)), elongation (epsilon(b)) and Young's modulus (E) determination. An increase of 97.4, 119 and 139% of sigma(b) was obtained for nanocomposites with addition of 0.25 wt.% of diallylamine, p-phenylenediamine/methyl ester of linseed oil fatty acid and hexamethylenediamine/methyl ester of linseed oil fatty acid multi-walled carbon nanotubes, respectively. Short techno-economic analysis, performed on the basis of fixed and variable unsaturated polyester resin production costs, showed satisfactory potential profit, which could be realized by the implementation of the presented technology.",
publisher = "Sage Publications Ltd, London",
journal = "Journal of Composite Materials",
title = "Effect of the vinyl modification of multi-walled carbon nanotubes on the performances of waste poly(ethylene terephthalate)-based nanocomposites",
pages = "505-491",
number = "4",
volume = "51",
doi = "10.1177/0021998316648757"
}

Tasić, A., Rusmirović, J. D., Nikolić, J., Božić, A., Pavlović, V., Marinković, A. D.,& Uskoković, P. S.. (2017). Effect of the vinyl modification of multi-walled carbon nanotubes on the performances of waste poly(ethylene terephthalate)-based nanocomposites. in Journal of Composite Materials
Sage Publications Ltd, London., 51(4), 491-505.
https://doi.org/10.1177/0021998316648757

Tasić A, Rusmirović JD, Nikolić J, Božić A, Pavlović V, Marinković AD, Uskoković PS. Effect of the vinyl modification of multi-walled carbon nanotubes on the performances of waste poly(ethylene terephthalate)-based nanocomposites. in Journal of Composite Materials. 2017;51(4):491-505.
doi:10.1177/0021998316648757 .

Tasić, Ana, Rusmirović, Jelena D., Nikolić, Jovana, Božić, Aleksandra, Pavlović, Vladimir, Marinković, Aleksandar D., Uskoković, Petar S., "Effect of the vinyl modification of multi-walled carbon nanotubes on the performances of waste poly(ethylene terephthalate)-based nanocomposites" in Journal of Composite Materials, 51, no. 4 (2017):491-505,
https://doi.org/10.1177/0021998316648757 . .

TY  - JOUR
AU  - Božić, Aleksandra
AU  - Marinković, Aleksandar
AU  - Bjelogrlić, Snežana
AU  - Todorović, Tamara R.
AU  - Cvijetić, Ilija N.
AU  - Novaković, Irena
AU  - Muller, Christian D.
AU  - Filipović, Nenad
PY  - 2016
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4065
AB  - A comparative study of antitumor activity of mono- and bis-quinoline based (thio) carbohydrazones was investigated by a series of tests on two human malignant cell lines: acute monocytic leukemia (THP-1) and pancreatic adenocarcinoma cancer stem cells (AsPC-1). Thiocarbohydrazones (TCHs) revealed superior pro-apoptotic activity over carbohydrazones (CHs) on both tested cell phenotypes, also displaying multi-target profile activities. Programmed cell death triggered by TCHs was partially caspase-dependent, mainly caspase-8 related. Activity against cancer stem cells (CSCs) was evaluated on 2D monolayers and 3D spheroidal models, where two out of three tested bis-TCHs successfully stimulated apoptosis accompanied by a reduction in size of treated spheres. Additionally, all bis-TCHs induced significant decrease in percentage of CD44-expressing AsPC-1 cells that indicate on their ability to induce reprogramming of CSC phenotype. Current results highly support further assessment of bis-TCHs in order to specify their specific targets in cancer cells and particularly in the CSCs subpopulation.
PB  - Royal Soc Chemistry, Cambridge
T2  - RSC Advances
T1  - Quinoline based mono- and bis-(thio) carbohydrazones: synthesis, anticancer activity in 2D and 3D cancer and cancer stem cell models
EP  - 104781
IS  - 106
SP  - 104763
VL  - 6
DO  - 10.1039/c6ra23940d
ER  - 

@article{
author = "Božić, Aleksandra and Marinković, Aleksandar and Bjelogrlić, Snežana and Todorović, Tamara R. and Cvijetić, Ilija N. and Novaković, Irena and Muller, Christian D. and Filipović, Nenad",
year = "2016",
abstract = "A comparative study of antitumor activity of mono- and bis-quinoline based (thio) carbohydrazones was investigated by a series of tests on two human malignant cell lines: acute monocytic leukemia (THP-1) and pancreatic adenocarcinoma cancer stem cells (AsPC-1). Thiocarbohydrazones (TCHs) revealed superior pro-apoptotic activity over carbohydrazones (CHs) on both tested cell phenotypes, also displaying multi-target profile activities. Programmed cell death triggered by TCHs was partially caspase-dependent, mainly caspase-8 related. Activity against cancer stem cells (CSCs) was evaluated on 2D monolayers and 3D spheroidal models, where two out of three tested bis-TCHs successfully stimulated apoptosis accompanied by a reduction in size of treated spheres. Additionally, all bis-TCHs induced significant decrease in percentage of CD44-expressing AsPC-1 cells that indicate on their ability to induce reprogramming of CSC phenotype. Current results highly support further assessment of bis-TCHs in order to specify their specific targets in cancer cells and particularly in the CSCs subpopulation.",
publisher = "Royal Soc Chemistry, Cambridge",
journal = "RSC Advances",
title = "Quinoline based mono- and bis-(thio) carbohydrazones: synthesis, anticancer activity in 2D and 3D cancer and cancer stem cell models",
pages = "104781-104763",
number = "106",
volume = "6",
doi = "10.1039/c6ra23940d"
}

Božić, A., Marinković, A., Bjelogrlić, S., Todorović, T. R., Cvijetić, I. N., Novaković, I., Muller, C. D.,& Filipović, N.. (2016). Quinoline based mono- and bis-(thio) carbohydrazones: synthesis, anticancer activity in 2D and 3D cancer and cancer stem cell models. in RSC Advances
Royal Soc Chemistry, Cambridge., 6(106), 104763-104781.
https://doi.org/10.1039/c6ra23940d

Božić A, Marinković A, Bjelogrlić S, Todorović TR, Cvijetić IN, Novaković I, Muller CD, Filipović N. Quinoline based mono- and bis-(thio) carbohydrazones: synthesis, anticancer activity in 2D and 3D cancer and cancer stem cell models. in RSC Advances. 2016;6(106):104763-104781.
doi:10.1039/c6ra23940d .

Božić, Aleksandra, Marinković, Aleksandar, Bjelogrlić, Snežana, Todorović, Tamara R., Cvijetić, Ilija N., Novaković, Irena, Muller, Christian D., Filipović, Nenad, "Quinoline based mono- and bis-(thio) carbohydrazones: synthesis, anticancer activity in 2D and 3D cancer and cancer stem cell models" in RSC Advances, 6, no. 106 (2016):104763-104781,
https://doi.org/10.1039/c6ra23940d . .