TY  - JOUR
AU  - Ribani, A.
AU  - Utzeri, Valerio J.
AU  - Geraci, Claudia
AU  - Tinarelli, S.
AU  - Djan, M.
AU  - Velicković, N.
AU  - Doneva, R.
AU  - Dall'Olio, S.
AU  - Costa, L.Nanni
AU  - Schiavo, Giuseppina
AU  - Bovo, Samuele
AU  - Usai, Graziano
AU  - Gallo, Maurizio
AU  - Radović, Čedomir
AU  - Savić, Radomir
AU  - Karolyi, Danijel
AU  - Salajpal, K.
AU  - Gvozdanović, K.
AU  - Djurkin-Kusec, Ivona
AU  - Skrlep, Martin
AU  - Čandek-Potokar, Marjeta
AU  - Ovilo, Cristina
AU  - Fontanesi, Luca
PY  - 2019
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/5109
AB  - Autochthonous pig breeds are usually reared in extensive or semi-extensive production systems that might facilitate contact with wild boars and, thus, reciprocal genetic exchanges. In this study, we analysed variants in the melanocortin 1 receptor (MC1R) gene (which cause different coat colour phenotypes) and in the nuclear receptor subfamily 6 group A member 1 (NR6A1) gene (associated with increased vertebral number) in 712 pigs of 12 local pig breeds raised in Italy (Apulo-Calabrese, Casertana, Cinta Senese, Mora Romagnola, Nero Siciliano and Sarda) and south-eastern European countries (Krskopolje from Slovenia, Black Slavonian and Turopolje from Croatia, Mangalitsa and Moravka from Serbia and East Balkan Swine from Bulgaria) and compared the data with the genetic variability at these loci investigated in 229 wild boars from populations spread in the same macro-geographic areas. None of the autochthonous pig breeds or wild boar populations were fixed for one allele at both loci. Domestic and wild-type alleles at these two genes were present in both domestic and wild populations. Findings of the distribution of MC1R alleles might be useful for tracing back the complex genetic history of autochthonous breeds. Altogether, these results indirectly demonstrate that bidirectional introgression of wild and domestic alleles is derived and affected by the human and naturally driven evolutionary forces that are shaping the Sus scrofa genome: autochthonous breeds are experiencing a sort of 'de-domestication' process, and wild resources are challenged by a 'domestication' drift. Both need to be further investigated and managed.
PB  - Wiley, Hoboken
T2  - Animal Genetics
T1  - Signatures of de-domestication in autochthonous pig breeds and of domestication in wild boar populations from MC1R and NR6A1 allele distribution
EP  - 171
IS  - 2
SP  - 166
VL  - 50
DO  - 10.1111/age.12771
ER  - 

@article{
author = "Ribani, A. and Utzeri, Valerio J. and Geraci, Claudia and Tinarelli, S. and Djan, M. and Velicković, N. and Doneva, R. and Dall'Olio, S. and Costa, L.Nanni and Schiavo, Giuseppina and Bovo, Samuele and Usai, Graziano and Gallo, Maurizio and Radović, Čedomir and Savić, Radomir and Karolyi, Danijel and Salajpal, K. and Gvozdanović, K. and Djurkin-Kusec, Ivona and Skrlep, Martin and Čandek-Potokar, Marjeta and Ovilo, Cristina and Fontanesi, Luca",
year = "2019",
abstract = "Autochthonous pig breeds are usually reared in extensive or semi-extensive production systems that might facilitate contact with wild boars and, thus, reciprocal genetic exchanges. In this study, we analysed variants in the melanocortin 1 receptor (MC1R) gene (which cause different coat colour phenotypes) and in the nuclear receptor subfamily 6 group A member 1 (NR6A1) gene (associated with increased vertebral number) in 712 pigs of 12 local pig breeds raised in Italy (Apulo-Calabrese, Casertana, Cinta Senese, Mora Romagnola, Nero Siciliano and Sarda) and south-eastern European countries (Krskopolje from Slovenia, Black Slavonian and Turopolje from Croatia, Mangalitsa and Moravka from Serbia and East Balkan Swine from Bulgaria) and compared the data with the genetic variability at these loci investigated in 229 wild boars from populations spread in the same macro-geographic areas. None of the autochthonous pig breeds or wild boar populations were fixed for one allele at both loci. Domestic and wild-type alleles at these two genes were present in both domestic and wild populations. Findings of the distribution of MC1R alleles might be useful for tracing back the complex genetic history of autochthonous breeds. Altogether, these results indirectly demonstrate that bidirectional introgression of wild and domestic alleles is derived and affected by the human and naturally driven evolutionary forces that are shaping the Sus scrofa genome: autochthonous breeds are experiencing a sort of 'de-domestication' process, and wild resources are challenged by a 'domestication' drift. Both need to be further investigated and managed.",
publisher = "Wiley, Hoboken",
journal = "Animal Genetics",
title = "Signatures of de-domestication in autochthonous pig breeds and of domestication in wild boar populations from MC1R and NR6A1 allele distribution",
pages = "171-166",
number = "2",
volume = "50",
doi = "10.1111/age.12771"
}

Ribani, A., Utzeri, V. J., Geraci, C., Tinarelli, S., Djan, M., Velicković, N., Doneva, R., Dall'Olio, S., Costa, L.Nanni, Schiavo, G., Bovo, S., Usai, G., Gallo, M., Radović, Č., Savić, R., Karolyi, D., Salajpal, K., Gvozdanović, K., Djurkin-Kusec, I., Skrlep, M., Čandek-Potokar, M., Ovilo, C.,& Fontanesi, L.. (2019). Signatures of de-domestication in autochthonous pig breeds and of domestication in wild boar populations from MC1R and NR6A1 allele distribution. in Animal Genetics
Wiley, Hoboken., 50(2), 166-171.
https://doi.org/10.1111/age.12771

Ribani A, Utzeri VJ, Geraci C, Tinarelli S, Djan M, Velicković N, Doneva R, Dall'Olio S, Costa L, Schiavo G, Bovo S, Usai G, Gallo M, Radović Č, Savić R, Karolyi D, Salajpal K, Gvozdanović K, Djurkin-Kusec I, Skrlep M, Čandek-Potokar M, Ovilo C, Fontanesi L. Signatures of de-domestication in autochthonous pig breeds and of domestication in wild boar populations from MC1R and NR6A1 allele distribution. in Animal Genetics. 2019;50(2):166-171.
doi:10.1111/age.12771 .

Ribani, A., Utzeri, Valerio J., Geraci, Claudia, Tinarelli, S., Djan, M., Velicković, N., Doneva, R., Dall'Olio, S., Costa, L.Nanni, Schiavo, Giuseppina, Bovo, Samuele, Usai, Graziano, Gallo, Maurizio, Radović, Čedomir, Savić, Radomir, Karolyi, Danijel, Salajpal, K., Gvozdanović, K., Djurkin-Kusec, Ivona, Skrlep, Martin, Čandek-Potokar, Marjeta, Ovilo, Cristina, Fontanesi, Luca, "Signatures of de-domestication in autochthonous pig breeds and of domestication in wild boar populations from MC1R and NR6A1 allele distribution" in Animal Genetics, 50, no. 2 (2019):166-171,
https://doi.org/10.1111/age.12771 . .