TY  - JOUR
AU  - Kočović, Dušica M.
AU  - Bajuk-Bogdanović, Danica
AU  - Pećinar, Ilinka
AU  - Božić Nedeljković, Biljana
AU  - Daković, Marko
AU  - Andjus, Pavle R.
PY  - 2021
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/5949
AB  - The objective of the study was to describe cellular and molecular markers of radioprotection by anisomycin, focusing on the changes in rat brain tissue. Two-month-old Wistar rats were exposed to a 60Co radiation source at a dose of 6 Gy, with or without radioprotection with anisomycin (150 mg/kg) administered subcutaneously 30 min before or 3 or 6 h after irradiation. Survivors were analyzed 30 days after treatment. Astroglial and microglial responses were investigated based on the expression of glial markers assessed with immunohistochemistry, and quantitative changes in brain biomolecules were investigated by Raman microspectroscopy. In addition, blood plasma levels of pro-inflammatory (interleukin 6 and tumor necrosis factor α) and anti-inflammatory (interleukin 10) cytokines were assessed. We found that application of anisomycin either before or after irradiation significantly decreased the expression of the microglial marker Iba-1. We also found an increased intensity of Raman spectral bands related to nucleic acids, as well as an increased level of cytokines when anisomycin was applied after irradiation. This suggests that the radioprotective effects of anisomycin are by decreasing Iba-1 expression and stabilizing genetic material by increasing the level of nucleic acids.
PB  - Oxford University Press
T2  - Journal of Radiation Research
T1  - Assessment of cellular and molecular changes in the rat brain after gamma radiation and radioprotection by anisomycin
EP  - 803
IS  - 5
SP  - 793
VL  - 62
DO  - 10.1093/jrr/rrab045
ER  - 

@article{
author = "Kočović, Dušica M. and Bajuk-Bogdanović, Danica and Pećinar, Ilinka and Božić Nedeljković, Biljana and Daković, Marko and Andjus, Pavle R.",
year = "2021",
abstract = "The objective of the study was to describe cellular and molecular markers of radioprotection by anisomycin, focusing on the changes in rat brain tissue. Two-month-old Wistar rats were exposed to a 60Co radiation source at a dose of 6 Gy, with or without radioprotection with anisomycin (150 mg/kg) administered subcutaneously 30 min before or 3 or 6 h after irradiation. Survivors were analyzed 30 days after treatment. Astroglial and microglial responses were investigated based on the expression of glial markers assessed with immunohistochemistry, and quantitative changes in brain biomolecules were investigated by Raman microspectroscopy. In addition, blood plasma levels of pro-inflammatory (interleukin 6 and tumor necrosis factor α) and anti-inflammatory (interleukin 10) cytokines were assessed. We found that application of anisomycin either before or after irradiation significantly decreased the expression of the microglial marker Iba-1. We also found an increased intensity of Raman spectral bands related to nucleic acids, as well as an increased level of cytokines when anisomycin was applied after irradiation. This suggests that the radioprotective effects of anisomycin are by decreasing Iba-1 expression and stabilizing genetic material by increasing the level of nucleic acids.",
publisher = "Oxford University Press",
journal = "Journal of Radiation Research",
title = "Assessment of cellular and molecular changes in the rat brain after gamma radiation and radioprotection by anisomycin",
pages = "803-793",
number = "5",
volume = "62",
doi = "10.1093/jrr/rrab045"
}

Kočović, D. M., Bajuk-Bogdanović, D., Pećinar, I., Božić Nedeljković, B., Daković, M.,& Andjus, P. R.. (2021). Assessment of cellular and molecular changes in the rat brain after gamma radiation and radioprotection by anisomycin. in Journal of Radiation Research
Oxford University Press., 62(5), 793-803.
https://doi.org/10.1093/jrr/rrab045

Kočović DM, Bajuk-Bogdanović D, Pećinar I, Božić Nedeljković B, Daković M, Andjus PR. Assessment of cellular and molecular changes in the rat brain after gamma radiation and radioprotection by anisomycin. in Journal of Radiation Research. 2021;62(5):793-803.
doi:10.1093/jrr/rrab045 .

Kočović, Dušica M., Bajuk-Bogdanović, Danica, Pećinar, Ilinka, Božić Nedeljković, Biljana, Daković, Marko, Andjus, Pavle R., "Assessment of cellular and molecular changes in the rat brain after gamma radiation and radioprotection by anisomycin" in Journal of Radiation Research, 62, no. 5 (2021):793-803,
https://doi.org/10.1093/jrr/rrab045 . .

TY  - JOUR
AU  - Tanić, Milan N.
AU  - Cujić, Mirjana R.
AU  - Gajić, Boško
AU  - Daković, Marko Z.
AU  - Dragović, Snežana
PY  - 2018
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4736
AB  - The concentrations and spatial distribution of nine potentially harmful elements (PHEs), namely Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb and Zn, and their relation to soil properties were investigated in thirty soil profiles (0-50 cm depth) sampled around the largest Serbian coal-fired power plant (CFPP) "Nikola Tesla A." Soil properties were determined following standard procedures, and total contents of PHEs were analyzed by atomic absorption spectrometer. Concentrations of Cd, Co, Fe, Mn, Pb and Zn were the highest in soil profiles sampled 1 km away from the CFPP, concentrations of Ni and Cu gradually increased up to 4 km, and the highest Cr concentrations were measured in samples taken 6 km away from the CFPP. The highest concentration of PHEs analyzed, except Mn, corresponded with predominant wind directions. Depth did not show significant impact on distribution of any PHEs investigated. Among soil properties, the total organic carbon showed the closest relationship with the PHEs. Data were processed by a principal component analysis which enabled distinguishing anthropogenic from natural influences on soil properties and PHE contents. Although the impact of CFPP operations is obvious, assets of principal component analysis did not allow clear distinction of CFPP's contribution from parent material in enrichment of PHE contents in the soil in the study area.
PB  - Springer, New York
T2  - Environmental Earth Sciences
T1  - Content of the potentially harmful elements in soil around the major coal-fired power plant in Serbia: relation to soil characteristics, evaluation of spatial distribution and source apportionment
IS  - 1
VL  - 77
DO  - 10.1007/s12665-017-7214-4
ER  - 

@article{
author = "Tanić, Milan N. and Cujić, Mirjana R. and Gajić, Boško and Daković, Marko Z. and Dragović, Snežana",
year = "2018",
abstract = "The concentrations and spatial distribution of nine potentially harmful elements (PHEs), namely Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb and Zn, and their relation to soil properties were investigated in thirty soil profiles (0-50 cm depth) sampled around the largest Serbian coal-fired power plant (CFPP) "Nikola Tesla A." Soil properties were determined following standard procedures, and total contents of PHEs were analyzed by atomic absorption spectrometer. Concentrations of Cd, Co, Fe, Mn, Pb and Zn were the highest in soil profiles sampled 1 km away from the CFPP, concentrations of Ni and Cu gradually increased up to 4 km, and the highest Cr concentrations were measured in samples taken 6 km away from the CFPP. The highest concentration of PHEs analyzed, except Mn, corresponded with predominant wind directions. Depth did not show significant impact on distribution of any PHEs investigated. Among soil properties, the total organic carbon showed the closest relationship with the PHEs. Data were processed by a principal component analysis which enabled distinguishing anthropogenic from natural influences on soil properties and PHE contents. Although the impact of CFPP operations is obvious, assets of principal component analysis did not allow clear distinction of CFPP's contribution from parent material in enrichment of PHE contents in the soil in the study area.",
publisher = "Springer, New York",
journal = "Environmental Earth Sciences",
title = "Content of the potentially harmful elements in soil around the major coal-fired power plant in Serbia: relation to soil characteristics, evaluation of spatial distribution and source apportionment",
number = "1",
volume = "77",
doi = "10.1007/s12665-017-7214-4"
}

Tanić, M. N., Cujić, M. R., Gajić, B., Daković, M. Z.,& Dragović, S.. (2018). Content of the potentially harmful elements in soil around the major coal-fired power plant in Serbia: relation to soil characteristics, evaluation of spatial distribution and source apportionment. in Environmental Earth Sciences
Springer, New York., 77(1).
https://doi.org/10.1007/s12665-017-7214-4

Tanić MN, Cujić MR, Gajić B, Daković MZ, Dragović S. Content of the potentially harmful elements in soil around the major coal-fired power plant in Serbia: relation to soil characteristics, evaluation of spatial distribution and source apportionment. in Environmental Earth Sciences. 2018;77(1).
doi:10.1007/s12665-017-7214-4 .

Tanić, Milan N., Cujić, Mirjana R., Gajić, Boško, Daković, Marko Z., Dragović, Snežana, "Content of the potentially harmful elements in soil around the major coal-fired power plant in Serbia: relation to soil characteristics, evaluation of spatial distribution and source apportionment" in Environmental Earth Sciences, 77, no. 1 (2018),
https://doi.org/10.1007/s12665-017-7214-4 . .

TY  - JOUR
AU  - Sarap, Nataša B.
AU  - Rajacić, Milica M.
AU  - Dalović, Ivica G.
AU  - Šeremešić, Srdjan
AU  - Djordjević, Aleksandar
AU  - Janković, Marija M.
AU  - Daković, Marko Z.
PY  - 2016
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3999
AB  - n The present paper focuses on the determination of radiological characteristics of cultivated chernozem soil and crops from long-term field experiments, taking into account the importance of distribution and transfer of radionuclides in the soil-plant system, especially in agricultural cropland. The investigation was performed on the experimental fields where maize, winter wheat, and rapeseed were cultivated. Analysis of radioactivity included determination of the gross alpha and beta activity as a screening method, as well as the activities of the following radiouclides: natural (Pb-210, U-235, U-238, Ra-226, Th-232, K-40, Be-7) and artificial (Sr-90 and Cs-137). The activities of natural and artificial (Cs-137) radionuclides were determined by gamma spectrometry, while the artificial radionuclide Sr-90 was determined by a radiochemical analytical method. Based on the obtained results for the specific activity of K-40, Cs-137, and Sr-90, accumulation factors for these radionuclides were calculated in order to estimate transfer of radionuclides from soil to crops. The results of performed analyses showed that there is no increase of radioactivity that could endanger the food production through the grown crops.
PB  - Springer Heidelberg, Heidelberg
T2  - Environmental Science and Pollution Research
T1  - Distribution of natural and artificial radionuclides in chernozem soil/crop system from stationary experiments
EP  - 17773
IS  - 17
SP  - 17761
VL  - 23
DO  - 10.1007/s11356-016-6938-0
ER  - 

@article{
author = "Sarap, Nataša B. and Rajacić, Milica M. and Dalović, Ivica G. and Šeremešić, Srdjan and Djordjević, Aleksandar and Janković, Marija M. and Daković, Marko Z.",
year = "2016",
abstract = "n The present paper focuses on the determination of radiological characteristics of cultivated chernozem soil and crops from long-term field experiments, taking into account the importance of distribution and transfer of radionuclides in the soil-plant system, especially in agricultural cropland. The investigation was performed on the experimental fields where maize, winter wheat, and rapeseed were cultivated. Analysis of radioactivity included determination of the gross alpha and beta activity as a screening method, as well as the activities of the following radiouclides: natural (Pb-210, U-235, U-238, Ra-226, Th-232, K-40, Be-7) and artificial (Sr-90 and Cs-137). The activities of natural and artificial (Cs-137) radionuclides were determined by gamma spectrometry, while the artificial radionuclide Sr-90 was determined by a radiochemical analytical method. Based on the obtained results for the specific activity of K-40, Cs-137, and Sr-90, accumulation factors for these radionuclides were calculated in order to estimate transfer of radionuclides from soil to crops. The results of performed analyses showed that there is no increase of radioactivity that could endanger the food production through the grown crops.",
publisher = "Springer Heidelberg, Heidelberg",
journal = "Environmental Science and Pollution Research",
title = "Distribution of natural and artificial radionuclides in chernozem soil/crop system from stationary experiments",
pages = "17773-17761",
number = "17",
volume = "23",
doi = "10.1007/s11356-016-6938-0"
}

Sarap, N. B., Rajacić, M. M., Dalović, I. G., Šeremešić, S., Djordjević, A., Janković, M. M.,& Daković, M. Z.. (2016). Distribution of natural and artificial radionuclides in chernozem soil/crop system from stationary experiments. in Environmental Science and Pollution Research
Springer Heidelberg, Heidelberg., 23(17), 17761-17773.
https://doi.org/10.1007/s11356-016-6938-0

Sarap NB, Rajacić MM, Dalović IG, Šeremešić S, Djordjević A, Janković MM, Daković MZ. Distribution of natural and artificial radionuclides in chernozem soil/crop system from stationary experiments. in Environmental Science and Pollution Research. 2016;23(17):17761-17773.
doi:10.1007/s11356-016-6938-0 .

Sarap, Nataša B., Rajacić, Milica M., Dalović, Ivica G., Šeremešić, Srdjan, Djordjević, Aleksandar, Janković, Marija M., Daković, Marko Z., "Distribution of natural and artificial radionuclides in chernozem soil/crop system from stationary experiments" in Environmental Science and Pollution Research, 23, no. 17 (2016):17761-17773,
https://doi.org/10.1007/s11356-016-6938-0 . .

TY  - JOUR
AU  - Tanić, Milan N.
AU  - Jankovic Mandić, Ljiljana J.
AU  - Gajić, Boško
AU  - Daković, Marko Z.
AU  - Dragović, Snežana
AU  - Bacić, Goran G.
PY  - 2016
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/4063
AB  - This study evaluates the influence of the largest Serbian coal-fired power plant on radionuclide concentrations in soil profiles up to 50 cm in depth. Thirty soil profiles were sampled from the plant surroundings (up to 10 km distance) and analyzed using standard methods for soil physicochemical properties and gamma ray spectrometry for specific activities of natural radionuclides (K-40, Ra-226 and Th-232) Spatial and vertical distribution of radionuclides was determined and analyzed to show the relations between the specific activities in the soil and soil properties and the most influential factors of natural radionuclide variability were identified. The radiological indices for surface soil were calculated and radiological risk assessment was performed. The measured specific activities were similar to values of BACKGROUND:  levels for Serbia. The sampling depth did not show any significant influence on specific activities of natural radionuclides. The strongest predictor of specific activities of the investigated radionuclides was soil granulometry. All parameters of radiological risk assessment were below the recommended values and adopted limits. It appears that the coal-fired power plant does not have a significant impact on the spatial and vertical distribution of natural radionuclides in the area of interest, but technologically enhanced natural radioactivity as a consequence of the plant operations was identified within the first 1.5 km from the power plant.
PB  - Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd
T2  - Nuclear Technology & Radiation Protection
T1  - Natural radionuclides in soil profiles surrounding the largest coal-fired power plant in Serbia
EP  - 259
IS  - 3
SP  - 247
VL  - 31
DO  - 10.2298/NTRP1603247T
ER  - 

@article{
author = "Tanić, Milan N. and Jankovic Mandić, Ljiljana J. and Gajić, Boško and Daković, Marko Z. and Dragović, Snežana and Bacić, Goran G.",
year = "2016",
abstract = "This study evaluates the influence of the largest Serbian coal-fired power plant on radionuclide concentrations in soil profiles up to 50 cm in depth. Thirty soil profiles were sampled from the plant surroundings (up to 10 km distance) and analyzed using standard methods for soil physicochemical properties and gamma ray spectrometry for specific activities of natural radionuclides (K-40, Ra-226 and Th-232) Spatial and vertical distribution of radionuclides was determined and analyzed to show the relations between the specific activities in the soil and soil properties and the most influential factors of natural radionuclide variability were identified. The radiological indices for surface soil were calculated and radiological risk assessment was performed. The measured specific activities were similar to values of BACKGROUND:  levels for Serbia. The sampling depth did not show any significant influence on specific activities of natural radionuclides. The strongest predictor of specific activities of the investigated radionuclides was soil granulometry. All parameters of radiological risk assessment were below the recommended values and adopted limits. It appears that the coal-fired power plant does not have a significant impact on the spatial and vertical distribution of natural radionuclides in the area of interest, but technologically enhanced natural radioactivity as a consequence of the plant operations was identified within the first 1.5 km from the power plant.",
publisher = "Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd",
journal = "Nuclear Technology & Radiation Protection",
title = "Natural radionuclides in soil profiles surrounding the largest coal-fired power plant in Serbia",
pages = "259-247",
number = "3",
volume = "31",
doi = "10.2298/NTRP1603247T"
}

Tanić, M. N., Jankovic Mandić, L. J., Gajić, B., Daković, M. Z., Dragović, S.,& Bacić, G. G.. (2016). Natural radionuclides in soil profiles surrounding the largest coal-fired power plant in Serbia. in Nuclear Technology & Radiation Protection
Univerzitet u Beogradu - Institut za nuklearne nauke Vinča, Beograd., 31(3), 247-259.
https://doi.org/10.2298/NTRP1603247T

Tanić MN, Jankovic Mandić LJ, Gajić B, Daković MZ, Dragović S, Bacić GG. Natural radionuclides in soil profiles surrounding the largest coal-fired power plant in Serbia. in Nuclear Technology & Radiation Protection. 2016;31(3):247-259.
doi:10.2298/NTRP1603247T .

Tanić, Milan N., Jankovic Mandić, Ljiljana J., Gajić, Boško, Daković, Marko Z., Dragović, Snežana, Bacić, Goran G., "Natural radionuclides in soil profiles surrounding the largest coal-fired power plant in Serbia" in Nuclear Technology & Radiation Protection, 31, no. 3 (2016):247-259,
https://doi.org/10.2298/NTRP1603247T . .