TY  - JOUR
AU  - Filipović, Nenad
AU  - Stevanović, Magdalena
AU  - Radulović, Aleksandra
AU  - Pavlović, Vladimir
AU  - Uskoković, Dragan
PY  - 2013
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/3298
AB  - Poly(epsilon-caprolactone) (PCL) particles were prepared by physicochemical method with solvent/non-solvent systems. The synthetic polymer polyvinylpyrrolidone (PVP) and natural polymer poly(alpha,gamma,L-glutamic acid) (PGA), were used as stabilizers and their influence on size and morphology of the particles was examined. The results were compared with those obtained without the use of stabilizers. This study evaluated, for the first time, PGA as stabilizer of PCL particles and demonstrated that PGA is more efficient stabilizer of PCL particles than most commonly used PVP. The particles obtained by using PGA as stabilizer were spherical, with smooth surfaces and dimensions below 1 mu m. The drying conditions were also varied in order to examine their influence on the formation of PCL particles. The samples were characterized by Fourier-transform infrared spectroscopy, scanning electron microscopy, particle size distribution (DLS) and zeta potential measurements.
PB  - Elsevier Sci Ltd, Oxford
T2  - Composites Part B-Engineering
T1  - Facile synthesis of poly(epsilon-caprolactone) micro and nanospheres using different types of polyelectrolytes as stabilizers under ambient and elevated temperature
EP  - 1479
IS  - 1
SP  - 1471
VL  - 45
DO  - 10.1016/j.compositesb.2012.07.008
ER  - 

@article{
author = "Filipović, Nenad and Stevanović, Magdalena and Radulović, Aleksandra and Pavlović, Vladimir and Uskoković, Dragan",
year = "2013",
abstract = "Poly(epsilon-caprolactone) (PCL) particles were prepared by physicochemical method with solvent/non-solvent systems. The synthetic polymer polyvinylpyrrolidone (PVP) and natural polymer poly(alpha,gamma,L-glutamic acid) (PGA), were used as stabilizers and their influence on size and morphology of the particles was examined. The results were compared with those obtained without the use of stabilizers. This study evaluated, for the first time, PGA as stabilizer of PCL particles and demonstrated that PGA is more efficient stabilizer of PCL particles than most commonly used PVP. The particles obtained by using PGA as stabilizer were spherical, with smooth surfaces and dimensions below 1 mu m. The drying conditions were also varied in order to examine their influence on the formation of PCL particles. The samples were characterized by Fourier-transform infrared spectroscopy, scanning electron microscopy, particle size distribution (DLS) and zeta potential measurements.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Composites Part B-Engineering",
title = "Facile synthesis of poly(epsilon-caprolactone) micro and nanospheres using different types of polyelectrolytes as stabilizers under ambient and elevated temperature",
pages = "1479-1471",
number = "1",
volume = "45",
doi = "10.1016/j.compositesb.2012.07.008"
}

Filipović, N., Stevanović, M., Radulović, A., Pavlović, V.,& Uskoković, D.. (2013). Facile synthesis of poly(epsilon-caprolactone) micro and nanospheres using different types of polyelectrolytes as stabilizers under ambient and elevated temperature. in Composites Part B-Engineering
Elsevier Sci Ltd, Oxford., 45(1), 1471-1479.
https://doi.org/10.1016/j.compositesb.2012.07.008

Filipović N, Stevanović M, Radulović A, Pavlović V, Uskoković D. Facile synthesis of poly(epsilon-caprolactone) micro and nanospheres using different types of polyelectrolytes as stabilizers under ambient and elevated temperature. in Composites Part B-Engineering. 2013;45(1):1471-1479.
doi:10.1016/j.compositesb.2012.07.008 .

Filipović, Nenad, Stevanović, Magdalena, Radulović, Aleksandra, Pavlović, Vladimir, Uskoković, Dragan, "Facile synthesis of poly(epsilon-caprolactone) micro and nanospheres using different types of polyelectrolytes as stabilizers under ambient and elevated temperature" in Composites Part B-Engineering, 45, no. 1 (2013):1471-1479,
https://doi.org/10.1016/j.compositesb.2012.07.008 . .

TY  - CONF
AU  - Filipović, Nenad
AU  - Stevanović, Magdalena
AU  - Pavlović, Vladimir B.
AU  - Radulović, Aleksandra
AU  - Stojanović, Zoran S.
AU  - Uskoković, Dragan
PY  - 2011
UR  - http://dais.sanu.ac.rs/123456789/692
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/5705
AB  - Poly-ε-caprolactone (PCL) is a semicrystalline, biodegradable and biocompatible polymer. Its advantages, as high permeability to small drug molecules, failure to generate an acidic environment during degradation (as compared to polylactides and polyglycolides) and a slow degradation rate, make this aliphatic polyester suitable for extended long-term delivery over a period of more than one year. In this study PCL particles were prepared by physicochemical method with solvent/nonsolvent systems. The synthetic polymer polyvinylpyrrolidone (PVP) and natural polymer poly (α, γ, L-glutamic acid) (PGA), were used as stabilizers and their influence on size and morphology of the particles was examined. The results were compared with those obtained without the use of stabilizers. Characterization of obtained particles was performed by Fourier transform infrared spectroscopy. The morphology and size distribution were determined using SEM and particle analyzer.
PB  - Belgrade : Institute of Technical Sciences of the Serbian Academy of Sciences and Arts
C3  - Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia
T1  - Synthesis and the effect of processing parameters on characteristics of poly-ε-caprolactone micro- and nanospheres
EP  - 2
SP  - 2
UR  - https://hdl.handle.net/21.15107/rcub_dais_692
ER  - 

@conference{
author = "Filipović, Nenad and Stevanović, Magdalena and Pavlović, Vladimir B. and Radulović, Aleksandra and Stojanović, Zoran S. and Uskoković, Dragan",
year = "2011",
abstract = "Poly-ε-caprolactone (PCL) is a semicrystalline, biodegradable and biocompatible polymer. Its advantages, as high permeability to small drug molecules, failure to generate an acidic environment during degradation (as compared to polylactides and polyglycolides) and a slow degradation rate, make this aliphatic polyester suitable for extended long-term delivery over a period of more than one year. In this study PCL particles were prepared by physicochemical method with solvent/nonsolvent systems. The synthetic polymer polyvinylpyrrolidone (PVP) and natural polymer poly (α, γ, L-glutamic acid) (PGA), were used as stabilizers and their influence on size and morphology of the particles was examined. The results were compared with those obtained without the use of stabilizers. Characterization of obtained particles was performed by Fourier transform infrared spectroscopy. The morphology and size distribution were determined using SEM and particle analyzer.",
publisher = "Belgrade : Institute of Technical Sciences of the Serbian Academy of Sciences and Arts",
journal = "Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia",
title = "Synthesis and the effect of processing parameters on characteristics of poly-ε-caprolactone micro- and nanospheres",
pages = "2-2",
url = "https://hdl.handle.net/21.15107/rcub_dais_692"
}

Filipović, N., Stevanović, M., Pavlović, V. B., Radulović, A., Stojanović, Z. S.,& Uskoković, D.. (2011). Synthesis and the effect of processing parameters on characteristics of poly-ε-caprolactone micro- and nanospheres. in Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia
Belgrade : Institute of Technical Sciences of the Serbian Academy of Sciences and Arts., 2-2.
https://hdl.handle.net/21.15107/rcub_dais_692

Filipović N, Stevanović M, Pavlović VB, Radulović A, Stojanović ZS, Uskoković D. Synthesis and the effect of processing parameters on characteristics of poly-ε-caprolactone micro- and nanospheres. in Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia. 2011;:2-2.
https://hdl.handle.net/21.15107/rcub_dais_692 .

Filipović, Nenad, Stevanović, Magdalena, Pavlović, Vladimir B., Radulović, Aleksandra, Stojanović, Zoran S., Uskoković, Dragan, "Synthesis and the effect of processing parameters on characteristics of poly-ε-caprolactone micro- and nanospheres" in Program and the Book of Abstracts / Tenth Young Researchers' Conference Materials Science and Engineering, December 21-23, 2011, Belgrade, Serbia (2011):2-2,
https://hdl.handle.net/21.15107/rcub_dais_692 .