TY  - JOUR
AU  - Stojanova, Monika
AU  - Pantić, Milena
AU  - Karadelev, Mitko
AU  - Ivanovski, Vladimir
AU  - Nikšić, Miomir
PY  - 2022
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6157
AB  - In the last decade, in addition to the study of the nutritional composition of mushrooms, the study of biologically active
compounds occupies an important place. However, there is a need to fnd new and lesser known mushrooms species that
have biological activity and potential for application in industrial conditions. The aim of this research is to determine the
biological activity of aqueous and ethanolic extracts of Suillus granulatus wild mushroom through the determination of
the content of total carbohydrates, total, α and β-glucans, as bioactive compounds, as well as determination of cytotoxic
activity. Total carbohydrate content was determined using spectroscopic method, total, α and β-glucans were analysed
using specifc kits, and MTT test (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) was used for cytotoxic
activity. IR-ATR (infrared spectroscopy - attenuated total refection) spectra of mushroom extracts were performed, too.
Aqueous extracts had a higher content of total carbohydrates as well as glucan and had better cytotoxic activity against
HeLa cells, while ethanolic extract of Suillus granulatus was characterized with better cytotoxic activity against HepG2
cells. Based on IR-ATR, the presence of diferent types of carbohydrates, glucans, proteins, phenols and favonoids can
be observed in aqueous and ethanolic, which is one of the reasons for the diferences in their anticancer activity. The
analysed extracts are an excellent basis for their further application in various products in order to obtain functional food
with enriched biological value. Thus, using natural dietary supplements can signifcantly afect the positive changes in
the health of consumers.
PB  - Springer
T2  - Journal of Food Measurement and Characterization
T1  - Determination of biological activity of suillus granulatus mushroom extracts
VL  - 1
DO  - 10.1007/s11694-022-01525-9
ER  - 

@article{
author = "Stojanova, Monika and Pantić, Milena and Karadelev, Mitko and Ivanovski, Vladimir and Nikšić, Miomir",
year = "2022",
abstract = "In the last decade, in addition to the study of the nutritional composition of mushrooms, the study of biologically active
compounds occupies an important place. However, there is a need to fnd new and lesser known mushrooms species that
have biological activity and potential for application in industrial conditions. The aim of this research is to determine the
biological activity of aqueous and ethanolic extracts of Suillus granulatus wild mushroom through the determination of
the content of total carbohydrates, total, α and β-glucans, as bioactive compounds, as well as determination of cytotoxic
activity. Total carbohydrate content was determined using spectroscopic method, total, α and β-glucans were analysed
using specifc kits, and MTT test (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) was used for cytotoxic
activity. IR-ATR (infrared spectroscopy - attenuated total refection) spectra of mushroom extracts were performed, too.
Aqueous extracts had a higher content of total carbohydrates as well as glucan and had better cytotoxic activity against
HeLa cells, while ethanolic extract of Suillus granulatus was characterized with better cytotoxic activity against HepG2
cells. Based on IR-ATR, the presence of diferent types of carbohydrates, glucans, proteins, phenols and favonoids can
be observed in aqueous and ethanolic, which is one of the reasons for the diferences in their anticancer activity. The
analysed extracts are an excellent basis for their further application in various products in order to obtain functional food
with enriched biological value. Thus, using natural dietary supplements can signifcantly afect the positive changes in
the health of consumers.",
publisher = "Springer",
journal = "Journal of Food Measurement and Characterization",
title = "Determination of biological activity of suillus granulatus mushroom extracts",
volume = "1",
doi = "10.1007/s11694-022-01525-9"
}

Stojanova, M., Pantić, M., Karadelev, M., Ivanovski, V.,& Nikšić, M.. (2022). Determination of biological activity of suillus granulatus mushroom extracts. in Journal of Food Measurement and Characterization
Springer., 1.
https://doi.org/10.1007/s11694-022-01525-9

Stojanova M, Pantić M, Karadelev M, Ivanovski V, Nikšić M. Determination of biological activity of suillus granulatus mushroom extracts. in Journal of Food Measurement and Characterization. 2022;1.
doi:10.1007/s11694-022-01525-9 .

Stojanova, Monika, Pantić, Milena, Karadelev, Mitko, Ivanovski, Vladimir, Nikšić, Miomir, "Determination of biological activity of suillus granulatus mushroom extracts" in Journal of Food Measurement and Characterization, 1 (2022),
https://doi.org/10.1007/s11694-022-01525-9 . .