TY  - JOUR
AU  - Milutinović, Nađa
AU  - Stević, Milan
AU  - Špirović Trifunović, Bojana
AU  - Brkić, Dragica
PY  - 2023
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6897
AB  - Mefentriflukonazol je nova aktivna supstanca sa fungicidnim delovanjem, koja pripada izopropanol azolima, novoj podgrupi u okviru hemijske grupe triazola. Inhibira biosintezu sterola i odlikuje se veoma selektivnim delovanjem. Sistemični je fungicid sa protektivnim, kurativnim i eradikativnim delovanjem i koristi se za suzbijanje značajnih patogena strnih žita (Septoria spp., Puccinia spp., Ramularia collo-cygni, Rhynchosporium secalis). Za razliku od većine triazola, povučenih iz primene u poslednje 2-3 godine, uglavnom zbog repro-toksičnog i karcinogenog delovanja, mefentriflukonazol ne deluje karcinogeno, genotoksično ni reprotoksično. Takođe, nije akutno toksičan, ne iritira kožu i oči i ne izaziva specifičnu toksičnost za ciljne organe posle jednokratne ili višekratne izloženosti. U dodiru sa kožom može izazvati senzibilizaciju i to je jedino toksikološko svojstvo na osnovu koga je klasifikovan i obeležen. Akutna i hronična dijetarna izloženost svih populacionih grupa ovoj aktivnoj supstanci je niska, sa velikom marginom bezbednosti. Mefentriflukonazol nije akutno oralno i kontakt-no toksičan za pčele i nije toksičan za kišne gliste. Za akvatične organizme, ribe, beskičmenjake i alge je veoma toksičan akutno i hronično, dok je za organizme sedimenta i akvatične makrofite toksičan. Povoljna toksikološka svojstva mefen-triflukonazola i dobra efikasnost preporučuju ovu aktivnu supstancu kao dobru zamenu za triazole povučene iz primene.
AB  - Mefentrifluconazole is a new fungicidal active substance from the isopropanol-azoles, a new sub-class of triazoles. It inhibits sterols biosynthesis and is a
very selective fungicide. It is a systemic fungicide with protective, curative, and
eradicative activity. Its spectrum includes important pathogens of cereals (Septoria spp., Puccinia spp., Ramularia collo-cygni, Rhynchosporium secalis). Unlike
most triazoles, withdrawn from use in the last 2-3 years, mainly due to reprotoxic
and carcinogenic effects, mefentrifluconazole is neither carcinogenic, nor genotoxic or reprotoxic. In adition, it is not acutely toxic, is not irritant to skin or
eyes and does not cause specific toxicity to target organs after single or repeated
exposure. In contact with the skin, it can cause sensitization, and this is the only
toxicological property on the basis of which it is classified and labeled. Acute and
chronic dietary exposure of all population groups to this active substance is low,
with a large margin of safety. Mefentrifluconazole is not acutely toxic to bees
and earthworms. It is very toxic acutely and chronically for aquatic organisms,
fish, invertebrates, and algae, while it is toxic for sediment organisms and aquatic macrophytes. The favourable toxicological properties of mefentrifluconazole,
and good efficacy in control of important pathogens, recommend this active substance as a good substitute for withdrawn triazoles.
PB  - Univerzitet u Novom Sadu - Poljoprivredni fakultet - Departman za fitomedicinu i zaštitu životne sredine, Novi Sad
T2  - Biljni lekar
T1  - Mefentriflukonazol - novi fungicid iz grupe triazola
EP  - 612
IS  - 4
SP  - 594
VL  - 51
DO  - 10.5937/BiljLek2304594M
ER  - 

@article{
author = "Milutinović, Nađa and Stević, Milan and Špirović Trifunović, Bojana and Brkić, Dragica",
year = "2023",
abstract = "Mefentriflukonazol je nova aktivna supstanca sa fungicidnim delovanjem, koja pripada izopropanol azolima, novoj podgrupi u okviru hemijske grupe triazola. Inhibira biosintezu sterola i odlikuje se veoma selektivnim delovanjem. Sistemični je fungicid sa protektivnim, kurativnim i eradikativnim delovanjem i koristi se za suzbijanje značajnih patogena strnih žita (Septoria spp., Puccinia spp., Ramularia collo-cygni, Rhynchosporium secalis). Za razliku od većine triazola, povučenih iz primene u poslednje 2-3 godine, uglavnom zbog repro-toksičnog i karcinogenog delovanja, mefentriflukonazol ne deluje karcinogeno, genotoksično ni reprotoksično. Takođe, nije akutno toksičan, ne iritira kožu i oči i ne izaziva specifičnu toksičnost za ciljne organe posle jednokratne ili višekratne izloženosti. U dodiru sa kožom može izazvati senzibilizaciju i to je jedino toksikološko svojstvo na osnovu koga je klasifikovan i obeležen. Akutna i hronična dijetarna izloženost svih populacionih grupa ovoj aktivnoj supstanci je niska, sa velikom marginom bezbednosti. Mefentriflukonazol nije akutno oralno i kontakt-no toksičan za pčele i nije toksičan za kišne gliste. Za akvatične organizme, ribe, beskičmenjake i alge je veoma toksičan akutno i hronično, dok je za organizme sedimenta i akvatične makrofite toksičan. Povoljna toksikološka svojstva mefen-triflukonazola i dobra efikasnost preporučuju ovu aktivnu supstancu kao dobru zamenu za triazole povučene iz primene., Mefentrifluconazole is a new fungicidal active substance from the isopropanol-azoles, a new sub-class of triazoles. It inhibits sterols biosynthesis and is a
very selective fungicide. It is a systemic fungicide with protective, curative, and
eradicative activity. Its spectrum includes important pathogens of cereals (Septoria spp., Puccinia spp., Ramularia collo-cygni, Rhynchosporium secalis). Unlike
most triazoles, withdrawn from use in the last 2-3 years, mainly due to reprotoxic
and carcinogenic effects, mefentrifluconazole is neither carcinogenic, nor genotoxic or reprotoxic. In adition, it is not acutely toxic, is not irritant to skin or
eyes and does not cause specific toxicity to target organs after single or repeated
exposure. In contact with the skin, it can cause sensitization, and this is the only
toxicological property on the basis of which it is classified and labeled. Acute and
chronic dietary exposure of all population groups to this active substance is low,
with a large margin of safety. Mefentrifluconazole is not acutely toxic to bees
and earthworms. It is very toxic acutely and chronically for aquatic organisms,
fish, invertebrates, and algae, while it is toxic for sediment organisms and aquatic macrophytes. The favourable toxicological properties of mefentrifluconazole,
and good efficacy in control of important pathogens, recommend this active substance as a good substitute for withdrawn triazoles.",
publisher = "Univerzitet u Novom Sadu - Poljoprivredni fakultet - Departman za fitomedicinu i zaštitu životne sredine, Novi Sad",
journal = "Biljni lekar",
title = "Mefentriflukonazol - novi fungicid iz grupe triazola",
pages = "612-594",
number = "4",
volume = "51",
doi = "10.5937/BiljLek2304594M"
}

Milutinović, N., Stević, M., Špirović Trifunović, B.,& Brkić, D.. (2023). Mefentriflukonazol - novi fungicid iz grupe triazola. in Biljni lekar
Univerzitet u Novom Sadu - Poljoprivredni fakultet - Departman za fitomedicinu i zaštitu životne sredine, Novi Sad., 51(4), 594-612.
https://doi.org/10.5937/BiljLek2304594M

Milutinović N, Stević M, Špirović Trifunović B, Brkić D. Mefentriflukonazol - novi fungicid iz grupe triazola. in Biljni lekar. 2023;51(4):594-612.
doi:10.5937/BiljLek2304594M .

Milutinović, Nađa, Stević, Milan, Špirović Trifunović, Bojana, Brkić, Dragica, "Mefentriflukonazol - novi fungicid iz grupe triazola" in Biljni lekar, 51, no. 4 (2023):594-612,
https://doi.org/10.5937/BiljLek2304594M . .

TY  - JOUR
AU  - Milutinović, Nađa G.
AU  - Vojinović, Uroš D.
AU  - Koprivica, Staša Lj.
AU  - Živanović, Maja D.
AU  - Vasić, Tanja P.
AU  - Stević, Milan Ž.
PY  - 2022
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6174
AB  - The objective of this study was to determine the Colletotrichum acutatum isolates sensitivity to several chemical compounds in vitro and to find their possibilities as a potential control agents for anthracnose disease on strawberry. C. acutatum J.H. Simmonds, a causing agent of anthracnose, is a very important pathogen of strawberry, which leads to devastating losses in its production. The pathogen is effectively controlled by the fungicides. Thus their application is necessary for achieving high yield and fruit quality. The sensitivity of 14 isolates of C. acutatum, collected from commercial strawberry plantations in Serbia, to four fungicides, was examined by an in vitro sensitivity assay. Based on the results of morphological, pathogenic and molecular characterization (up to the complex level), all 14 isolates were determined as C. acutatum. The commercial formulation of tebuconazole, fludioxonil, prochloraz and thiophanate-methyl were used for the sensitivity test. The mycelial growth assay method was used to investigate isolates sensitivity to fungicides. The tested isolates were very sensitive to prochloraz and fludioxonil, with mean EC50 values of 0.067±0.062 mg L-1 and 0.093±0.043 mg L-1, respectively. Significantly higher mean EC50 values were observed for tebuconazole (1.473±0.878 mg L-1) and thiophanate-methyl (1.718±1.592 mg L-1). The toxicity of tested fungicides in the mycelial growth assay of C. acutatum isolates indicates the potential implementation of these fungicides in the protection programs against strawberry anthracnose disease. © Journal of Agricultural Sciences (Belgrade).All rights reserved.
T2  - Journal of Agricultural Sciences (Belgrade)
T2  - Journal of Agricultural Sciences (Belgrade)
T1  - IN VITRO SENSITIVITY OF COLLETOTRICHUM ACUTATUM ISOLATES FROM STRAWBERRY TO TEBUCONAZOLE, PROCHLORAZ, FLUDIOXONIL AND THIOPHANATE-METHYL
EP  - 201
IS  - 2
SP  - 191
VL  - 67
DO  - 10.2298/JAS2202191M
ER  - 

@article{
author = "Milutinović, Nađa G. and Vojinović, Uroš D. and Koprivica, Staša Lj. and Živanović, Maja D. and Vasić, Tanja P. and Stević, Milan Ž.",
year = "2022",
abstract = "The objective of this study was to determine the Colletotrichum acutatum isolates sensitivity to several chemical compounds in vitro and to find their possibilities as a potential control agents for anthracnose disease on strawberry. C. acutatum J.H. Simmonds, a causing agent of anthracnose, is a very important pathogen of strawberry, which leads to devastating losses in its production. The pathogen is effectively controlled by the fungicides. Thus their application is necessary for achieving high yield and fruit quality. The sensitivity of 14 isolates of C. acutatum, collected from commercial strawberry plantations in Serbia, to four fungicides, was examined by an in vitro sensitivity assay. Based on the results of morphological, pathogenic and molecular characterization (up to the complex level), all 14 isolates were determined as C. acutatum. The commercial formulation of tebuconazole, fludioxonil, prochloraz and thiophanate-methyl were used for the sensitivity test. The mycelial growth assay method was used to investigate isolates sensitivity to fungicides. The tested isolates were very sensitive to prochloraz and fludioxonil, with mean EC50 values of 0.067±0.062 mg L-1 and 0.093±0.043 mg L-1, respectively. Significantly higher mean EC50 values were observed for tebuconazole (1.473±0.878 mg L-1) and thiophanate-methyl (1.718±1.592 mg L-1). The toxicity of tested fungicides in the mycelial growth assay of C. acutatum isolates indicates the potential implementation of these fungicides in the protection programs against strawberry anthracnose disease. © Journal of Agricultural Sciences (Belgrade).All rights reserved.",
journal = "Journal of Agricultural Sciences (Belgrade), Journal of Agricultural Sciences (Belgrade)",
title = "IN VITRO SENSITIVITY OF COLLETOTRICHUM ACUTATUM ISOLATES FROM STRAWBERRY TO TEBUCONAZOLE, PROCHLORAZ, FLUDIOXONIL AND THIOPHANATE-METHYL",
pages = "201-191",
number = "2",
volume = "67",
doi = "10.2298/JAS2202191M"
}

Milutinović, N. G., Vojinović, U. D., Koprivica, S. Lj., Živanović, M. D., Vasić, T. P.,& Stević, M. Ž.. (2022). IN VITRO SENSITIVITY OF COLLETOTRICHUM ACUTATUM ISOLATES FROM STRAWBERRY TO TEBUCONAZOLE, PROCHLORAZ, FLUDIOXONIL AND THIOPHANATE-METHYL. in Journal of Agricultural Sciences (Belgrade), 67(2), 191-201.
https://doi.org/10.2298/JAS2202191M

Milutinović NG, Vojinović UD, Koprivica SL, Živanović MD, Vasić TP, Stević MŽ. IN VITRO SENSITIVITY OF COLLETOTRICHUM ACUTATUM ISOLATES FROM STRAWBERRY TO TEBUCONAZOLE, PROCHLORAZ, FLUDIOXONIL AND THIOPHANATE-METHYL. in Journal of Agricultural Sciences (Belgrade). 2022;67(2):191-201.
doi:10.2298/JAS2202191M .

Milutinović, Nađa G., Vojinović, Uroš D., Koprivica, Staša Lj., Živanović, Maja D., Vasić, Tanja P., Stević, Milan Ž., "IN VITRO SENSITIVITY OF COLLETOTRICHUM ACUTATUM ISOLATES FROM STRAWBERRY TO TEBUCONAZOLE, PROCHLORAZ, FLUDIOXONIL AND THIOPHANATE-METHYL" in Journal of Agricultural Sciences (Belgrade), 67, no. 2 (2022):191-201,
https://doi.org/10.2298/JAS2202191M . .

TY  - JOUR
AU  - Milutinović, Nađa
AU  - Vojinović, Uroš
AU  - Stević, Milan
PY  - 2021
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6898
AB  - U toku 2020. godine, vršeno je ispitivanje biološke efikasnosti fungicida propamokarb – hidrohlorid + fluopikolid, cimoksanil, mandipropamid + difenokonazol
i dimetomorf + mankozeb u suzbijanju prouzrokovača plamenjače (Phytophthora
infestans) u usevu paradajza.
 Ogledi su izvedeni na lokalitetima Sovljak (Ub), Belosavci (Topola) i Garaši
(Aranđelovac), po tipu potpuno slučajnog blok sistema u četiri ponavljanja (EPPO,
1996). Na svakom lokalitetu izvršeno je po pet tretiranja, a ocene efekata vršene su
u dva navrata. Povoljni agrometeorološki uslovi rezultirali su značajnom pojavom
oboljenja u kontroli, koja je iznosila 17,5-41,3% u prvoj, odnosno, 28,8-95,0% u
vreme druge ocene efekata.
Primenom kombinacije fungicida propamokarb-hidrohlorid+fluopikolid ostvarena je efikasnost u iznosu od 94,5-99,4% u prvoj, odnosno, 92,3-97,9% u drugoj
oceni. Cimoksanil je ispoljio efikasnost koja je iznosila 83,0-92,9% u prvoj, i 80,0-
89,5% u drugoj oceni. Kombinacijom fungicida mandipropamid+difenokonazol
postignuta je efikasnost od 89,1 do 99,7% u prvoj, odnosno 88,2-98,5% u vreme
druge ocene efekata. Sa kombinacijom fungicida dimetomorf+mankozeb ostvarena
efkasnost iznosila je 94,1-97,8% u prvoj, odnosno 90,7-97,7% u drugoj oceni.
AB  - During the season 2020, the biological efficacy of fungicides propamocarb
hydrochloride + fluopicolide, cymoxanil, mandipropamide + difenoconazole and
dimothomorph + mancozeb in the control of late blight (Phytophthora infestans)
in tomato, was investigated. The experiments were conducted in the localities of
Sovljak (Ub), Belosavci (Topola) and Garaši (Aranđelovac). The experiments were
carried out as a randomized block system in four replication (EPPO, 1996). A total
of five treatments and two assessments were performed at each location. Favorable
conditions resulted in a significant disease intensity on untreated plots, which amounted from 17,5-41,3% in the first, and 28,8-95,0% during the second assessment.
Fungicide mixture propamocarb-hydrochloride+fluopicolide, showed the efficacy from 94,5-99,4% at the first, and 92,3-97,9% at the second assessment. Fungicide cymoxanil, showed the efficacy of 83,0-92,9% at the first, and 80,0-89,5%
at the second assessment. Fungicide mixture mandipropamide+difenoconazole
achieved the efficacy from 89,1-99,7% at the first, and 88,2-98,5% during the second assessment. By a combination of dimothomorph+mancozeb the efficacy was
ranged from 94,1-97,8% at the first and from 90,7-97,7% at the second assessment.
PB  - Univerzitet u Novom Sadu - Poljoprivredni fakultet - Departman za fitomedicinu i zaštitu životne sredine, Novi Sad
T2  - Biljni lekar
T1  - Efikasnost fungicida u suzbijanju prouzrokovača plamenjače paradajza (Phytophthora infestans (Mont.) de Bary) u uslovima jake pojave oboljenja
EP  - 200
IS  - 2
SP  - 188
VL  - 49
DO  - 10.5937/BiljLek2102188M
ER  - 

@article{
author = "Milutinović, Nađa and Vojinović, Uroš and Stević, Milan",
year = "2021",
abstract = "U toku 2020. godine, vršeno je ispitivanje biološke efikasnosti fungicida propamokarb – hidrohlorid + fluopikolid, cimoksanil, mandipropamid + difenokonazol
i dimetomorf + mankozeb u suzbijanju prouzrokovača plamenjače (Phytophthora
infestans) u usevu paradajza.
 Ogledi su izvedeni na lokalitetima Sovljak (Ub), Belosavci (Topola) i Garaši
(Aranđelovac), po tipu potpuno slučajnog blok sistema u četiri ponavljanja (EPPO,
1996). Na svakom lokalitetu izvršeno je po pet tretiranja, a ocene efekata vršene su
u dva navrata. Povoljni agrometeorološki uslovi rezultirali su značajnom pojavom
oboljenja u kontroli, koja je iznosila 17,5-41,3% u prvoj, odnosno, 28,8-95,0% u
vreme druge ocene efekata.
Primenom kombinacije fungicida propamokarb-hidrohlorid+fluopikolid ostvarena je efikasnost u iznosu od 94,5-99,4% u prvoj, odnosno, 92,3-97,9% u drugoj
oceni. Cimoksanil je ispoljio efikasnost koja je iznosila 83,0-92,9% u prvoj, i 80,0-
89,5% u drugoj oceni. Kombinacijom fungicida mandipropamid+difenokonazol
postignuta je efikasnost od 89,1 do 99,7% u prvoj, odnosno 88,2-98,5% u vreme
druge ocene efekata. Sa kombinacijom fungicida dimetomorf+mankozeb ostvarena
efkasnost iznosila je 94,1-97,8% u prvoj, odnosno 90,7-97,7% u drugoj oceni., During the season 2020, the biological efficacy of fungicides propamocarb
hydrochloride + fluopicolide, cymoxanil, mandipropamide + difenoconazole and
dimothomorph + mancozeb in the control of late blight (Phytophthora infestans)
in tomato, was investigated. The experiments were conducted in the localities of
Sovljak (Ub), Belosavci (Topola) and Garaši (Aranđelovac). The experiments were
carried out as a randomized block system in four replication (EPPO, 1996). A total
of five treatments and two assessments were performed at each location. Favorable
conditions resulted in a significant disease intensity on untreated plots, which amounted from 17,5-41,3% in the first, and 28,8-95,0% during the second assessment.
Fungicide mixture propamocarb-hydrochloride+fluopicolide, showed the efficacy from 94,5-99,4% at the first, and 92,3-97,9% at the second assessment. Fungicide cymoxanil, showed the efficacy of 83,0-92,9% at the first, and 80,0-89,5%
at the second assessment. Fungicide mixture mandipropamide+difenoconazole
achieved the efficacy from 89,1-99,7% at the first, and 88,2-98,5% during the second assessment. By a combination of dimothomorph+mancozeb the efficacy was
ranged from 94,1-97,8% at the first and from 90,7-97,7% at the second assessment.",
publisher = "Univerzitet u Novom Sadu - Poljoprivredni fakultet - Departman za fitomedicinu i zaštitu životne sredine, Novi Sad",
journal = "Biljni lekar",
title = "Efikasnost fungicida u suzbijanju prouzrokovača plamenjače paradajza (Phytophthora infestans (Mont.) de Bary) u uslovima jake pojave oboljenja",
pages = "200-188",
number = "2",
volume = "49",
doi = "10.5937/BiljLek2102188M"
}

Milutinović, N., Vojinović, U.,& Stević, M.. (2021). Efikasnost fungicida u suzbijanju prouzrokovača plamenjače paradajza (Phytophthora infestans (Mont.) de Bary) u uslovima jake pojave oboljenja. in Biljni lekar
Univerzitet u Novom Sadu - Poljoprivredni fakultet - Departman za fitomedicinu i zaštitu životne sredine, Novi Sad., 49(2), 188-200.
https://doi.org/10.5937/BiljLek2102188M

Milutinović N, Vojinović U, Stević M. Efikasnost fungicida u suzbijanju prouzrokovača plamenjače paradajza (Phytophthora infestans (Mont.) de Bary) u uslovima jake pojave oboljenja. in Biljni lekar. 2021;49(2):188-200.
doi:10.5937/BiljLek2102188M .

Milutinović, Nađa, Vojinović, Uroš, Stević, Milan, "Efikasnost fungicida u suzbijanju prouzrokovača plamenjače paradajza (Phytophthora infestans (Mont.) de Bary) u uslovima jake pojave oboljenja" in Biljni lekar, 49, no. 2 (2021):188-200,
https://doi.org/10.5937/BiljLek2102188M . .