TY  - JOUR
AU  - Kokanov, Sanja B.
AU  - Filipović, Nenad R.
AU  - Višnjevac, Aleksandar
AU  - Nikolić, Milan
AU  - Novaković, Irena
AU  - Janjić, Goran
AU  - Holló, Berta Barta
AU  - Ramotowska, Sandra
AU  - Nowicka, Paulina
AU  - Makowski, Mariusz
AU  - Uğuz, Özlem
AU  - Koca, Atıf
AU  - Todorović, Tamara R.
PY  - 2022
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/6221
AB  - Interest in Cd complexes has been growing in recent years. Cd complexes are considered a potential solution in the search for novel antibiotics that can fight antimicrobial resistance. In addition, Cd complexes draw attention to material chemistry. The main objective of this work was to prepare the first Cd(II) complexes with anionic forms of pyridine-based thiazolyl hydrazone (THs) ligands HLS2 [(E)-4-(4-methoxyphenyl)-2-(2-[pyridine-2-ylmethylene]hydrazinyl)thiazole] and HLS3 [(E)-2-(2-[pyridine-2-ylmethylene]hydrazinyl)-4-(p-tolyl)thiazole] and perform their structural and spectroscopic characterization, as well as stability in solution and upon heating. Studies related to their biological activities and possible electrochromic applications are also being conducted. Complexes [Cd(HLS2)2] (1) and [Cd(HLS3)2] (2) have been characterized by a single-crystal X-ray diffraction and computational analysis of intermolecular interactions responsible for their solid-state structures was performed. Thermal stability of 1 and 2 in the solid-state was analyzed by TGA/MS, where as their solution stability was determined by the spectrophotometric titration method. Electrochemical and in situ UV–Vis spectroelectrochemical analyses of 1 and 2 were carried out to determine redox mechanisms and the influence of the substituents and electrolytes on their redox responses. The antioxidant capacity of both complexes was tested in antioxidant assays, while their antimicrobial activity was tested against five Gram-positive and four Gram-negative bacteria, as well as against three fungi. The obtained results indicate their potent antioxidant capacity. The antimicrobial activity of investigated compounds on almost all tested bacterial strains was stronger than that of the standard antibiotic erythromycin. The results of docking studies indicate that the minor groove DNA is the possible biological target of 1 and 2. © 2022 John Wiley & Sons Ltd.
T2  - Applied Organometallic Chemistry
T2  - Applied Organometallic Chemistry
T1  - A detailed experimental and computational study of Cd complexes with pyridyl-based thiazolyl hydrazones
DO  - 10.1002/aoc.6942
ER  - 

@article{
author = "Kokanov, Sanja B. and Filipović, Nenad R. and Višnjevac, Aleksandar and Nikolić, Milan and Novaković, Irena and Janjić, Goran and Holló, Berta Barta and Ramotowska, Sandra and Nowicka, Paulina and Makowski, Mariusz and Uğuz, Özlem and Koca, Atıf and Todorović, Tamara R.",
year = "2022",
abstract = "Interest in Cd complexes has been growing in recent years. Cd complexes are considered a potential solution in the search for novel antibiotics that can fight antimicrobial resistance. In addition, Cd complexes draw attention to material chemistry. The main objective of this work was to prepare the first Cd(II) complexes with anionic forms of pyridine-based thiazolyl hydrazone (THs) ligands HLS2 [(E)-4-(4-methoxyphenyl)-2-(2-[pyridine-2-ylmethylene]hydrazinyl)thiazole] and HLS3 [(E)-2-(2-[pyridine-2-ylmethylene]hydrazinyl)-4-(p-tolyl)thiazole] and perform their structural and spectroscopic characterization, as well as stability in solution and upon heating. Studies related to their biological activities and possible electrochromic applications are also being conducted. Complexes [Cd(HLS2)2] (1) and [Cd(HLS3)2] (2) have been characterized by a single-crystal X-ray diffraction and computational analysis of intermolecular interactions responsible for their solid-state structures was performed. Thermal stability of 1 and 2 in the solid-state was analyzed by TGA/MS, where as their solution stability was determined by the spectrophotometric titration method. Electrochemical and in situ UV–Vis spectroelectrochemical analyses of 1 and 2 were carried out to determine redox mechanisms and the influence of the substituents and electrolytes on their redox responses. The antioxidant capacity of both complexes was tested in antioxidant assays, while their antimicrobial activity was tested against five Gram-positive and four Gram-negative bacteria, as well as against three fungi. The obtained results indicate their potent antioxidant capacity. The antimicrobial activity of investigated compounds on almost all tested bacterial strains was stronger than that of the standard antibiotic erythromycin. The results of docking studies indicate that the minor groove DNA is the possible biological target of 1 and 2. © 2022 John Wiley & Sons Ltd.",
journal = "Applied Organometallic Chemistry, Applied Organometallic Chemistry",
title = "A detailed experimental and computational study of Cd complexes with pyridyl-based thiazolyl hydrazones",
doi = "10.1002/aoc.6942"
}

Kokanov, S. B., Filipović, N. R., Višnjevac, A., Nikolić, M., Novaković, I., Janjić, G., Holló, B. B., Ramotowska, S., Nowicka, P., Makowski, M., Uğuz, Ö., Koca, A.,& Todorović, T. R.. (2022). A detailed experimental and computational study of Cd complexes with pyridyl-based thiazolyl hydrazones. in Applied Organometallic Chemistry.
https://doi.org/10.1002/aoc.6942

Kokanov SB, Filipović NR, Višnjevac A, Nikolić M, Novaković I, Janjić G, Holló BB, Ramotowska S, Nowicka P, Makowski M, Uğuz Ö, Koca A, Todorović TR. A detailed experimental and computational study of Cd complexes with pyridyl-based thiazolyl hydrazones. in Applied Organometallic Chemistry. 2022;.
doi:10.1002/aoc.6942 .

Kokanov, Sanja B., Filipović, Nenad R., Višnjevac, Aleksandar, Nikolić, Milan, Novaković, Irena, Janjić, Goran, Holló, Berta Barta, Ramotowska, Sandra, Nowicka, Paulina, Makowski, Mariusz, Uğuz, Özlem, Koca, Atıf, Todorović, Tamara R., "A detailed experimental and computational study of Cd complexes with pyridyl-based thiazolyl hydrazones" in Applied Organometallic Chemistry (2022),
https://doi.org/10.1002/aoc.6942 . .

TY  - JOUR
AU  - Rajković, Miloš
AU  - Stanojević, Dušan D.
AU  - Novaković, I.D.
AU  - Tošković, D.V.
AU  - Sudar, M.M.
PY  - 2009
UR  - http://aspace.agrif.bg.ac.rs/handle/123456789/1859
AB  - The amount of total acids in must is in most number of cases between 5 and 8 g/dm3 . Wines in general possess a little fewer acids than must, by Regulation the least acidity, expressed as tartaric acid is for all kinds of wine 4.5 g/dm3 , because a part of tartaric acids sediments as salt (tartar) in the process of the alcohol fermentation. For wines that possess less than 4 g/dm3 of total acids there is a doubt are they of natural BACKGROUND: . Because of that the aim of this work was determination of total acids in diferent sorts of red wines and to determinate their BACKGROUND:  using gained data. For determinating total acids in white wine neutralization method was used. As potentiometric titration for pH 7.00 is precise and accurate method and values of content of total acids in wine, exppressed by tartaric acid, are given by these results. The analisys of differential potentiometric curves indicates that these curves can give the answer to the questions: are there inorganic supstances, amino groups and phenols present in analised samples.
PB  - University of East Sarajevo, Faculty of Technology
T2  - Journal of Engineering & Processing Management
T1  - The determinations of total acids in red wine
EP  - 153
IS  - 2
SP  - 140
VL  - 1
UR  - https://hdl.handle.net/21.15107/rcub_agrospace_1859
ER  - 

@article{
author = "Rajković, Miloš and Stanojević, Dušan D. and Novaković, I.D. and Tošković, D.V. and Sudar, M.M.",
year = "2009",
abstract = "The amount of total acids in must is in most number of cases between 5 and 8 g/dm3 . Wines in general possess a little fewer acids than must, by Regulation the least acidity, expressed as tartaric acid is for all kinds of wine 4.5 g/dm3 , because a part of tartaric acids sediments as salt (tartar) in the process of the alcohol fermentation. For wines that possess less than 4 g/dm3 of total acids there is a doubt are they of natural BACKGROUND: . Because of that the aim of this work was determination of total acids in diferent sorts of red wines and to determinate their BACKGROUND:  using gained data. For determinating total acids in white wine neutralization method was used. As potentiometric titration for pH 7.00 is precise and accurate method and values of content of total acids in wine, exppressed by tartaric acid, are given by these results. The analisys of differential potentiometric curves indicates that these curves can give the answer to the questions: are there inorganic supstances, amino groups and phenols present in analised samples.",
publisher = "University of East Sarajevo, Faculty of Technology",
journal = "Journal of Engineering & Processing Management",
title = "The determinations of total acids in red wine",
pages = "153-140",
number = "2",
volume = "1",
url = "https://hdl.handle.net/21.15107/rcub_agrospace_1859"
}

Rajković, M., Stanojević, D. D., Novaković, I.D., Tošković, D.V.,& Sudar, M.M.. (2009). The determinations of total acids in red wine. in Journal of Engineering & Processing Management
University of East Sarajevo, Faculty of Technology., 1(2), 140-153.
https://hdl.handle.net/21.15107/rcub_agrospace_1859

Rajković M, Stanojević DD, Novaković I, Tošković D, Sudar M. The determinations of total acids in red wine. in Journal of Engineering & Processing Management. 2009;1(2):140-153.
https://hdl.handle.net/21.15107/rcub_agrospace_1859 .

Rajković, Miloš, Stanojević, Dušan D., Novaković, I.D., Tošković, D.V., Sudar, M.M., "The determinations of total acids in red wine" in Journal of Engineering & Processing Management, 1, no. 2 (2009):140-153,
https://hdl.handle.net/21.15107/rcub_agrospace_1859 .