Evaluation of Antimicrobial Activity of Kitaibelia vitifolia Extract against Proven Antibiotic-Susceptible and Multidrug-Resistant (MDR) Strains of Bacteria of Clinical Origin
Аутори
Kurćubić, Vladimir S.Raketić, Svetlana V.
Mašković, Jelena M.
Mašković, Pavle Z.
Kurćubić, Luka V.
Heinz, Volker
Tomasevic, Igor B.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The goal of the present research was to screen the antimicrobial activity of an ethanolic extract of Kitaibelia vitifolia against 30 multidrug-resistant (MDR) bacterial strains isolated from healthcare-associated infections. Minimum inhibitory concentrations (MICs) of the samples against the tested bacteria were determined using the microdilution method. MDR bacterial strains were characterized using standard biochemical tests and the commercial identification systems API 20 NE and API 20 E as: Klebsiella spp. (18 isolates-I); methicillin-resistant Staphylococcus aureus (MRSA)-3; Acinetobacter spp.-3; Pseudomonas aeruginosa-5; vancomycin-resistant Enterococcus (VRE)-1. The sensitivity of isolated bacterial strains was determined using the disc diffusion method against 25 commonly used antibiotics. The highest level of sensitivity to K. vitifolia extract was confirmed in 88.89% of Klebsiella spp. isolates, E. coli ATCC 25922, two strains of MRSA (1726, 1063), Acinetobacter spp. strain 1...578, and VRE strain 30, like Enterococcus faecalis ATCC 29212 (MIC =< 2.44 μg/mL). The lowest sensitivity was exhibited by 75.00% of Acinetobacter spp. (strains 1577 and 6401), where the highest values for MICs were noted (1250 μg/mL). The results indicate that the extract of K. vitifolia could be a possible source for creating new, efficient, and effective natural medicines for combat against MDR strains of bacteria.
Кључне речи:
antibacterial activity / disc diffusion method / Kitaibelia vitifolia / minimum inhibitory concentration / multidrug resistant bacteriaИзвор:
Plants (Basel, Switzerland), 2023, 12, 18, 3236-Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200088 (Универзитет у Крагујевцу, Агрономски факултет, Чачак) (RS-MESTD-inst-2020-200088)
Институција/група
Poljoprivredni fakultetTY - JOUR AU - Kurćubić, Vladimir S. AU - Raketić, Svetlana V. AU - Mašković, Jelena M. AU - Mašković, Pavle Z. AU - Kurćubić, Luka V. AU - Heinz, Volker AU - Tomasevic, Igor B. PY - 2023 UR - http://www.ncbi.nlm.nih.gov/pubmed/37765400 UR - http://aspace.agrif.bg.ac.rs/handle/123456789/6465 AB - The goal of the present research was to screen the antimicrobial activity of an ethanolic extract of Kitaibelia vitifolia against 30 multidrug-resistant (MDR) bacterial strains isolated from healthcare-associated infections. Minimum inhibitory concentrations (MICs) of the samples against the tested bacteria were determined using the microdilution method. MDR bacterial strains were characterized using standard biochemical tests and the commercial identification systems API 20 NE and API 20 E as: Klebsiella spp. (18 isolates-I); methicillin-resistant Staphylococcus aureus (MRSA)-3; Acinetobacter spp.-3; Pseudomonas aeruginosa-5; vancomycin-resistant Enterococcus (VRE)-1. The sensitivity of isolated bacterial strains was determined using the disc diffusion method against 25 commonly used antibiotics. The highest level of sensitivity to K. vitifolia extract was confirmed in 88.89% of Klebsiella spp. isolates, E. coli ATCC 25922, two strains of MRSA (1726, 1063), Acinetobacter spp. strain 1578, and VRE strain 30, like Enterococcus faecalis ATCC 29212 (MIC =< 2.44 μg/mL). The lowest sensitivity was exhibited by 75.00% of Acinetobacter spp. (strains 1577 and 6401), where the highest values for MICs were noted (1250 μg/mL). The results indicate that the extract of K. vitifolia could be a possible source for creating new, efficient, and effective natural medicines for combat against MDR strains of bacteria. T2 - Plants (Basel, Switzerland) T2 - Plants (Basel, Switzerland)Plants (Basel) T1 - Evaluation of Antimicrobial Activity of Kitaibelia vitifolia Extract against Proven Antibiotic-Susceptible and Multidrug-Resistant (MDR) Strains of Bacteria of Clinical Origin IS - 18 SP - 3236 VL - 12 DO - 10.3390/plants12183236 ER -
@article{ author = "Kurćubić, Vladimir S. and Raketić, Svetlana V. and Mašković, Jelena M. and Mašković, Pavle Z. and Kurćubić, Luka V. and Heinz, Volker and Tomasevic, Igor B.", year = "2023", abstract = "The goal of the present research was to screen the antimicrobial activity of an ethanolic extract of Kitaibelia vitifolia against 30 multidrug-resistant (MDR) bacterial strains isolated from healthcare-associated infections. Minimum inhibitory concentrations (MICs) of the samples against the tested bacteria were determined using the microdilution method. MDR bacterial strains were characterized using standard biochemical tests and the commercial identification systems API 20 NE and API 20 E as: Klebsiella spp. (18 isolates-I); methicillin-resistant Staphylococcus aureus (MRSA)-3; Acinetobacter spp.-3; Pseudomonas aeruginosa-5; vancomycin-resistant Enterococcus (VRE)-1. The sensitivity of isolated bacterial strains was determined using the disc diffusion method against 25 commonly used antibiotics. The highest level of sensitivity to K. vitifolia extract was confirmed in 88.89% of Klebsiella spp. isolates, E. coli ATCC 25922, two strains of MRSA (1726, 1063), Acinetobacter spp. strain 1578, and VRE strain 30, like Enterococcus faecalis ATCC 29212 (MIC =< 2.44 μg/mL). The lowest sensitivity was exhibited by 75.00% of Acinetobacter spp. (strains 1577 and 6401), where the highest values for MICs were noted (1250 μg/mL). The results indicate that the extract of K. vitifolia could be a possible source for creating new, efficient, and effective natural medicines for combat against MDR strains of bacteria.", journal = "Plants (Basel, Switzerland), Plants (Basel, Switzerland)Plants (Basel)", title = "Evaluation of Antimicrobial Activity of Kitaibelia vitifolia Extract against Proven Antibiotic-Susceptible and Multidrug-Resistant (MDR) Strains of Bacteria of Clinical Origin", number = "18", pages = "3236", volume = "12", doi = "10.3390/plants12183236" }
Kurćubić, V. S., Raketić, S. V., Mašković, J. M., Mašković, P. Z., Kurćubić, L. V., Heinz, V.,& Tomasevic, I. B.. (2023). Evaluation of Antimicrobial Activity of Kitaibelia vitifolia Extract against Proven Antibiotic-Susceptible and Multidrug-Resistant (MDR) Strains of Bacteria of Clinical Origin. in Plants (Basel, Switzerland), 12(18), 3236. https://doi.org/10.3390/plants12183236
Kurćubić VS, Raketić SV, Mašković JM, Mašković PZ, Kurćubić LV, Heinz V, Tomasevic IB. Evaluation of Antimicrobial Activity of Kitaibelia vitifolia Extract against Proven Antibiotic-Susceptible and Multidrug-Resistant (MDR) Strains of Bacteria of Clinical Origin. in Plants (Basel, Switzerland). 2023;12(18):3236. doi:10.3390/plants12183236 .
Kurćubić, Vladimir S., Raketić, Svetlana V., Mašković, Jelena M., Mašković, Pavle Z., Kurćubić, Luka V., Heinz, Volker, Tomasevic, Igor B., "Evaluation of Antimicrobial Activity of Kitaibelia vitifolia Extract against Proven Antibiotic-Susceptible and Multidrug-Resistant (MDR) Strains of Bacteria of Clinical Origin" in Plants (Basel, Switzerland), 12, no. 18 (2023):3236, https://doi.org/10.3390/plants12183236 . .