Potential of Fumagillin and Agaricus blazei Mushroom Extract to Reduce Nosema ceranae in Honey Bees
Autori
Glavinić, UrošStevanović, Jevrosima
Ristanić, Marko
Rajković, Milan
Davitkov, Dajana
Lakić, Nada
Stanimirović, Zoran
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
Depending on the infection level and colony strength, Nosema ceranae, a microsporidian endoparasite of the honey bee may have significant consequences on the health, reproduction and productivity of bee colonies. Despite exerting some side effects, fumagillin is most often used for Nosema control. In this study, in a cage experiment, N. ceranae infected bees were treated with fumagillin or the extract of Agaricus blazei mushroom, a possible alternative for Nosema control. Bee survival, Nosema spore loads, the expression levels of immune-related genes and parameters of oxidative stress were observed. Fumagillin treatment showed a negative effect on monitored parameters when applied preventively to non-infected bees, while a noticeable anti-Nosema effect and protection from Nosema-induced immunosuppression and oxidative stress were proven in Nosema-infected bees. However, a protective effect of the natural A. blazei extract was detected, without any side effects but with immunostimulator...y activity in the preventive application. The results of this research suggest the potential of A. blazei extract for Nosema control, which needs to be further investigated.
Ključne reči:
Agaricus blazei / Antioxidative protection / Fumagillin / Honey bee / Immune-related gene expression / Immunostimu-lation / Mushroom extract / Nosema ceranaeIzvor:
Insects, 2021, 12, 4, 282-Izdavač:
- MDPI AG
Finansiranje / projekti:
DOI: 10.3390/insects12040282
ISSN: 2075-4450
WoS: 000643087400001
Scopus: 2-s2.0-85103840355
Institucija/grupa
Poljoprivredni fakultetTY - JOUR AU - Glavinić, Uroš AU - Stevanović, Jevrosima AU - Ristanić, Marko AU - Rajković, Milan AU - Davitkov, Dajana AU - Lakić, Nada AU - Stanimirović, Zoran PY - 2021 UR - http://aspace.agrif.bg.ac.rs/handle/123456789/5832 AB - Depending on the infection level and colony strength, Nosema ceranae, a microsporidian endoparasite of the honey bee may have significant consequences on the health, reproduction and productivity of bee colonies. Despite exerting some side effects, fumagillin is most often used for Nosema control. In this study, in a cage experiment, N. ceranae infected bees were treated with fumagillin or the extract of Agaricus blazei mushroom, a possible alternative for Nosema control. Bee survival, Nosema spore loads, the expression levels of immune-related genes and parameters of oxidative stress were observed. Fumagillin treatment showed a negative effect on monitored parameters when applied preventively to non-infected bees, while a noticeable anti-Nosema effect and protection from Nosema-induced immunosuppression and oxidative stress were proven in Nosema-infected bees. However, a protective effect of the natural A. blazei extract was detected, without any side effects but with immunostimulatory activity in the preventive application. The results of this research suggest the potential of A. blazei extract for Nosema control, which needs to be further investigated. PB - MDPI AG T2 - Insects T1 - Potential of Fumagillin and Agaricus blazei Mushroom Extract to Reduce Nosema ceranae in Honey Bees IS - 4 SP - 282 VL - 12 DO - 10.3390/insects12040282 ER -
@article{ author = "Glavinić, Uroš and Stevanović, Jevrosima and Ristanić, Marko and Rajković, Milan and Davitkov, Dajana and Lakić, Nada and Stanimirović, Zoran", year = "2021", abstract = "Depending on the infection level and colony strength, Nosema ceranae, a microsporidian endoparasite of the honey bee may have significant consequences on the health, reproduction and productivity of bee colonies. Despite exerting some side effects, fumagillin is most often used for Nosema control. In this study, in a cage experiment, N. ceranae infected bees were treated with fumagillin or the extract of Agaricus blazei mushroom, a possible alternative for Nosema control. Bee survival, Nosema spore loads, the expression levels of immune-related genes and parameters of oxidative stress were observed. Fumagillin treatment showed a negative effect on monitored parameters when applied preventively to non-infected bees, while a noticeable anti-Nosema effect and protection from Nosema-induced immunosuppression and oxidative stress were proven in Nosema-infected bees. However, a protective effect of the natural A. blazei extract was detected, without any side effects but with immunostimulatory activity in the preventive application. The results of this research suggest the potential of A. blazei extract for Nosema control, which needs to be further investigated.", publisher = "MDPI AG", journal = "Insects", title = "Potential of Fumagillin and Agaricus blazei Mushroom Extract to Reduce Nosema ceranae in Honey Bees", number = "4", pages = "282", volume = "12", doi = "10.3390/insects12040282" }
Glavinić, U., Stevanović, J., Ristanić, M., Rajković, M., Davitkov, D., Lakić, N.,& Stanimirović, Z.. (2021). Potential of Fumagillin and Agaricus blazei Mushroom Extract to Reduce Nosema ceranae in Honey Bees. in Insects MDPI AG., 12(4), 282. https://doi.org/10.3390/insects12040282
Glavinić U, Stevanović J, Ristanić M, Rajković M, Davitkov D, Lakić N, Stanimirović Z. Potential of Fumagillin and Agaricus blazei Mushroom Extract to Reduce Nosema ceranae in Honey Bees. in Insects. 2021;12(4):282. doi:10.3390/insects12040282 .
Glavinić, Uroš, Stevanović, Jevrosima, Ristanić, Marko, Rajković, Milan, Davitkov, Dajana, Lakić, Nada, Stanimirović, Zoran, "Potential of Fumagillin and Agaricus blazei Mushroom Extract to Reduce Nosema ceranae in Honey Bees" in Insects, 12, no. 4 (2021):282, https://doi.org/10.3390/insects12040282 . .