Occupational and environmental aspects of organophosphorus compounds
Abstract
Besides being a potential risk to humans and other living organisms, organophosphorus (OP) compounds also poses a risk to the environment. Production and placing pesticides on the market are under national and international legislative framework, although in many developing countries the regulation is still inadequate or not properly enforced. Occupational exposure to OPs includes any job which involves either direct or indirect contact with OP compounds, while public exposure to OPs may occur through contaminated food or from hand-to-mouth contact with contaminated surfaces, inhalation and dermal contact. The aim of this chapter is to present a comprehensive review of control and regulation measures, risk assessment methods, types and modality of occupational and environmental exposure to OPs, and ecotoxicology of these compounds. Review of the literature on OP exposure in electronic bibliographic databases, textbooks, and Internet sources was done. The acute high-dose effects of OPs ...are well known and include neurological dysfunction due to the inhibition of acetylcholinesterase (AChE), while effects of low-level exposure are still a matter of controversy. Advances in analytical methods help scientists to find new biomarkers of exposure and tools for biological monitoring and regulations of occupational exposure.
Keywords:
Butyrylcholinesterase / Chemical weapons convention / Dialkyl phosphate / Diethyldithiophosphate / Diethylphosphate / Diethylthiophosphate / Dimethyldithiophosphate / Dimethylphosphate / DimethylthiophosSource:
Basic and Clinical Toxicology of Organophosphorus Compounds, 2014, 213-244Publisher:
- Springer-Verlag London Ltd
Funding / projects:
- Development of integrated management of harmful organisms in plant production in order to overcome resistance and to improve food quality and safety (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46008)
- Improvement and development of hygienic and technological procedures in production of animal originating foodstuffs with the aim of producing high-quality and safe products competetive on the global market (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46009)
- Geologic and ecotoxicologic research in identification of geopathogen zones of toxic elements in drinking water reservoirs- research into methods and procedures for reduction of biochemical anomalies (RS-MESTD-Basic Research (BR or ON)-176018)
Collections
Institution/Community
Poljoprivredni fakultetTY - CHAP AU - Vučinić, S. AU - Antonijević, B. AU - Brkić, Dragica PY - 2014 UR - http://aspace.agrif.bg.ac.rs/handle/123456789/3471 AB - Besides being a potential risk to humans and other living organisms, organophosphorus (OP) compounds also poses a risk to the environment. Production and placing pesticides on the market are under national and international legislative framework, although in many developing countries the regulation is still inadequate or not properly enforced. Occupational exposure to OPs includes any job which involves either direct or indirect contact with OP compounds, while public exposure to OPs may occur through contaminated food or from hand-to-mouth contact with contaminated surfaces, inhalation and dermal contact. The aim of this chapter is to present a comprehensive review of control and regulation measures, risk assessment methods, types and modality of occupational and environmental exposure to OPs, and ecotoxicology of these compounds. Review of the literature on OP exposure in electronic bibliographic databases, textbooks, and Internet sources was done. The acute high-dose effects of OPs are well known and include neurological dysfunction due to the inhibition of acetylcholinesterase (AChE), while effects of low-level exposure are still a matter of controversy. Advances in analytical methods help scientists to find new biomarkers of exposure and tools for biological monitoring and regulations of occupational exposure. PB - Springer-Verlag London Ltd T2 - Basic and Clinical Toxicology of Organophosphorus Compounds T1 - Occupational and environmental aspects of organophosphorus compounds EP - 244 SP - 213 DO - 10.1007/978-1-4471-5625-3_8 ER -
@inbook{ author = "Vučinić, S. and Antonijević, B. and Brkić, Dragica", year = "2014", abstract = "Besides being a potential risk to humans and other living organisms, organophosphorus (OP) compounds also poses a risk to the environment. Production and placing pesticides on the market are under national and international legislative framework, although in many developing countries the regulation is still inadequate or not properly enforced. Occupational exposure to OPs includes any job which involves either direct or indirect contact with OP compounds, while public exposure to OPs may occur through contaminated food or from hand-to-mouth contact with contaminated surfaces, inhalation and dermal contact. The aim of this chapter is to present a comprehensive review of control and regulation measures, risk assessment methods, types and modality of occupational and environmental exposure to OPs, and ecotoxicology of these compounds. Review of the literature on OP exposure in electronic bibliographic databases, textbooks, and Internet sources was done. The acute high-dose effects of OPs are well known and include neurological dysfunction due to the inhibition of acetylcholinesterase (AChE), while effects of low-level exposure are still a matter of controversy. Advances in analytical methods help scientists to find new biomarkers of exposure and tools for biological monitoring and regulations of occupational exposure.", publisher = "Springer-Verlag London Ltd", journal = "Basic and Clinical Toxicology of Organophosphorus Compounds", booktitle = "Occupational and environmental aspects of organophosphorus compounds", pages = "244-213", doi = "10.1007/978-1-4471-5625-3_8" }
Vučinić, S., Antonijević, B.,& Brkić, D.. (2014). Occupational and environmental aspects of organophosphorus compounds. in Basic and Clinical Toxicology of Organophosphorus Compounds Springer-Verlag London Ltd., 213-244. https://doi.org/10.1007/978-1-4471-5625-3_8
Vučinić S, Antonijević B, Brkić D. Occupational and environmental aspects of organophosphorus compounds. in Basic and Clinical Toxicology of Organophosphorus Compounds. 2014;:213-244. doi:10.1007/978-1-4471-5625-3_8 .
Vučinić, S., Antonijević, B., Brkić, Dragica, "Occupational and environmental aspects of organophosphorus compounds" in Basic and Clinical Toxicology of Organophosphorus Compounds (2014):213-244, https://doi.org/10.1007/978-1-4471-5625-3_8 . .