Synthesis, characterization and in vitro evaluation of divalent ion release from stable NiFe2O4, ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 nanoparticles
Само за регистроване кориснике
2020
Аутори
Andjelković, LjubicaJeremić, Dejan
Milenković, Milica R.
Radosavljević, Jelena
Vulić, Predrag J.
Pavlović, Vladimir
Manojlović, Dragan
Nikolić, Aleksandar S.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
A simple organic-phase synthesis process was used to produce bare NiFe2O4 and ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 ferrite nanoparticles. X-ray powder diffractograms for all investigated powders show characteristic peaks of a spinel cubic structure without a secondary phase. Transmission electron microscopy (TEM) indicated the presence of nanoparticles that are smaller than 20 nm. The release of divalent ions (Ni2+ and Zn2+) from synthesized nanoparticles that were dispersed in saline solution, phosphate-buffered saline (PBS) and human serum, as determined by the inductively coupled plasma mass spectrometry (ICP-MS) method, was lower than 2 wt %. These results demonstrate the stability of the investigated nanoparticles in biologically relevant media and exclude the toxicity of Ni2+ and Zn2+ due to metal ion release, thereby opening a broad range of (bio)medical applications.
Кључне речи:
Ferrites / Bimagnetic core-shell nanoparticles / Ni2+ and Zn2+ leakageИзвор:
Ceramics International, 2020, 46, 3, 3528-3533Издавач:
- Elsevier Sci Ltd, Oxford
Финансирање / пројекти:
- Рационални дизајн и синтеза биолошки активних и координационих једињења и функционалних материјала, релевантних у (био)нанотехнологији (RS-172035)
- Молекуларне особине и модификације неких респираторних и нутритивних алергена (RS-172024)
- Примена унапређених оксидационих процеса и наноструктурисаних оксидних материјала за уклањање загађивача из животне средине, развој и оптимизација инструменталних техника за праћење ефикасности (RS-172030)
- Интеракције природних производа, њихових деривата и комплексних једињења са протеинима и нуклеинским киселинама (RS-172055)
DOI: 10.1016/j.ceramint.2019.10.068
ISSN: 0272-8842
WoS: 000508752000114
Scopus: 2-s2.0-85073150109
Институција/група
Poljoprivredni fakultetTY - JOUR AU - Andjelković, Ljubica AU - Jeremić, Dejan AU - Milenković, Milica R. AU - Radosavljević, Jelena AU - Vulić, Predrag J. AU - Pavlović, Vladimir AU - Manojlović, Dragan AU - Nikolić, Aleksandar S. PY - 2020 UR - http://aspace.agrif.bg.ac.rs/handle/123456789/5327 AB - A simple organic-phase synthesis process was used to produce bare NiFe2O4 and ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 ferrite nanoparticles. X-ray powder diffractograms for all investigated powders show characteristic peaks of a spinel cubic structure without a secondary phase. Transmission electron microscopy (TEM) indicated the presence of nanoparticles that are smaller than 20 nm. The release of divalent ions (Ni2+ and Zn2+) from synthesized nanoparticles that were dispersed in saline solution, phosphate-buffered saline (PBS) and human serum, as determined by the inductively coupled plasma mass spectrometry (ICP-MS) method, was lower than 2 wt %. These results demonstrate the stability of the investigated nanoparticles in biologically relevant media and exclude the toxicity of Ni2+ and Zn2+ due to metal ion release, thereby opening a broad range of (bio)medical applications. PB - Elsevier Sci Ltd, Oxford T2 - Ceramics International T1 - Synthesis, characterization and in vitro evaluation of divalent ion release from stable NiFe2O4, ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 nanoparticles EP - 3533 IS - 3 SP - 3528 VL - 46 DO - 10.1016/j.ceramint.2019.10.068 ER -
@article{ author = "Andjelković, Ljubica and Jeremić, Dejan and Milenković, Milica R. and Radosavljević, Jelena and Vulić, Predrag J. and Pavlović, Vladimir and Manojlović, Dragan and Nikolić, Aleksandar S.", year = "2020", abstract = "A simple organic-phase synthesis process was used to produce bare NiFe2O4 and ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 ferrite nanoparticles. X-ray powder diffractograms for all investigated powders show characteristic peaks of a spinel cubic structure without a secondary phase. Transmission electron microscopy (TEM) indicated the presence of nanoparticles that are smaller than 20 nm. The release of divalent ions (Ni2+ and Zn2+) from synthesized nanoparticles that were dispersed in saline solution, phosphate-buffered saline (PBS) and human serum, as determined by the inductively coupled plasma mass spectrometry (ICP-MS) method, was lower than 2 wt %. These results demonstrate the stability of the investigated nanoparticles in biologically relevant media and exclude the toxicity of Ni2+ and Zn2+ due to metal ion release, thereby opening a broad range of (bio)medical applications.", publisher = "Elsevier Sci Ltd, Oxford", journal = "Ceramics International", title = "Synthesis, characterization and in vitro evaluation of divalent ion release from stable NiFe2O4, ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 nanoparticles", pages = "3533-3528", number = "3", volume = "46", doi = "10.1016/j.ceramint.2019.10.068" }
Andjelković, L., Jeremić, D., Milenković, M. R., Radosavljević, J., Vulić, P. J., Pavlović, V., Manojlović, D.,& Nikolić, A. S.. (2020). Synthesis, characterization and in vitro evaluation of divalent ion release from stable NiFe2O4, ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 nanoparticles. in Ceramics International Elsevier Sci Ltd, Oxford., 46(3), 3528-3533. https://doi.org/10.1016/j.ceramint.2019.10.068
Andjelković L, Jeremić D, Milenković MR, Radosavljević J, Vulić PJ, Pavlović V, Manojlović D, Nikolić AS. Synthesis, characterization and in vitro evaluation of divalent ion release from stable NiFe2O4, ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 nanoparticles. in Ceramics International. 2020;46(3):3528-3533. doi:10.1016/j.ceramint.2019.10.068 .
Andjelković, Ljubica, Jeremić, Dejan, Milenković, Milica R., Radosavljević, Jelena, Vulić, Predrag J., Pavlović, Vladimir, Manojlović, Dragan, Nikolić, Aleksandar S., "Synthesis, characterization and in vitro evaluation of divalent ion release from stable NiFe2O4, ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 nanoparticles" in Ceramics International, 46, no. 3 (2020):3528-3533, https://doi.org/10.1016/j.ceramint.2019.10.068 . .