Cyprinid herpesvirus diseases

Abstract

Cyprinidae, the largest known fish family including carp and minnows, has worldwide distribution with many species that are economically important in aquaculture. As would be expected, many viral pathogens can affect this group. The most pathogenic of these are the rhabdoviruses, a reovirus and three herpesviruses. Cyprinid herpesviruses can cause significant economic losses in aquaculture, and some of these viruses are oncogenic. The three herpesviruses are closely related but cause distinctly different diseases. Fish pox, caused by cyprinid herpesvirus 1 (CyHV-1), is one of the oldest known fish diseases, being recorded as early as 1563. It takes the form of a hyperplastic, epidermal papilloma on common carp. Cyprinid herpesvirus 2 (CyHV-2) is causative agent of herpesviral hematopoietic necrosis (HVHN). The herpesvirus was first isolated from cultured goldfish in Japan. It causes a severe epizootic but no external clinical signs were apparent on affected fish. One of the most economically important and researched viral diseases of carp is koi herpesviral disease caused by cyprinid herpesvirus 3 (CyHV-3). The aim of this paper is to present the current knowledge on herpesvirus diseases of the cyprinids.

Ciprinide, najveća poznata familija riba, koja obuhvata šaranske vrste riba, je rasprostranjena širom sveta, sa mnogim vrstama koje imaju veliki ekonomski značaj u akvakulturi. Kao što bi se moglo očekivati, mnogi virusi mogu delovati na ovu grupu, među kojima su od najvećeg značaja pripadnici familija rabdovirusa, reovirusa i herpesvirusa. Herpesvirusi ciprinida mogu izazvati značajne ekonomske gubitke u akvakulturi, a neki od njih virusa su onkogeni. Iako su veoma srodni herpesvirusi ciprinida izazivaju različite bolesti sa veoma različitim karakteristikama. Boginje riba, koje izaziva herpesvirus 1 (CyHV-1), je jedno od najstarijih poznatih bolesti riba, utvrđeno još 1563. godine. Ovo oboljenje se po pravilu ispoljava u vidu hiperplastičnih papilomatoznih promena epiderma šarana. Herpesvirus 2 (CyHV-2) je uzročnik herpesvirusne hematopoezne nekroze (HVHN). Ovaj virus je prvi put izolovan iz zlatnih ribica u Japanu. Kao posledica delovanja uzročnika dolazi do pojave značajnih epizootija bez izraženih kliničkih znakova kod obolelih riba. Jedno od ekonomski najznačajnijih virusnih oboljenja šarana je koi herpesviroza izazvana ciprinim herpesvirusom 3 (CyHV-3). Cilj ovog rada je da se predstave aktuelna saznanja o oboljenjima ciprinida izazvanih herpesvirusima.