Pseudo-blend model of hydrogel immobilized living cellst

Abstract

Living cell organization in clusters is considered in terms of cell-cells and cells-microenvironment interactions as important factor in fundamental understanding of cell behavior in formation and grow of living tissues, wound heeling and development some serious illness, but also in present tissue engineering, immobilization of cells in polymer matrices and culture grow. Significant importance of parameters as compacivity and compressibility for quantification of cell behavior is found as well as possibility for modeling cell organization in terms of classical models of polymer structure as blends. The theory of Karasz and coworkers on miscibility widows in polymer blends is used for interpretation of some polymer-cell relations.